The use of human sewage screening for community surveillance of hepatitis E virus in the UK

Donald B Smith, Julius O Paddy, Peter Simmonds

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-infected hepatitis patients. This article is protected by copyright. All rights reserved.

Original languageEnglish
Pages (from-to)915-918
JournalJournal of Medical Virology
Volume88
Issue number5
Early online date4 Nov 2015
DOIs
Publication statusPublished - May 2016

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