The use of human sewage screening for community surveillance of hepatitis E virus in the UK

Donald B Smith; Julius O Paddy; Peter Simmonds

doi:10.1002/jmv.24403

The use of human sewage screening for community surveillance of hepatitis E virus in the UK

Donald B Smith, Julius O Paddy, Peter Simmonds

Research output: Contribution to journal › Article › peer-review

Abstract

Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-infected hepatitis patients. This article is protected by copyright. All rights reserved.

Original language	English
Pages (from-to)	915-918
Journal	Journal of Medical Virology
Volume	88
Issue number	5
Early online date	4 Nov 2015
DOIs	https://doi.org/10.1002/jmv.24403
Publication status	Published - May 2016

Access to Document

10.1002/jmv.24403

The use of human sewage screening for community surveillance of hepatitis E virus in the UK
Available under Open Access.
Accepted author manuscript, 626 KB

http://onlinelibrary.wiley.com/doi/10.1002/jmv.24403/abstract

Cite this

@article{01cf366f2b4c4e65bf90c3b028102079,

title = "The use of human sewage screening for community surveillance of hepatitis E virus in the UK",

abstract = "Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-infected hepatitis patients. This article is protected by copyright. All rights reserved.",

author = "Smith, {Donald B} and Paddy, {Julius O} and Peter Simmonds",

year = "2016",

month = may,

doi = "10.1002/jmv.24403",

language = "English",

volume = "88",

pages = "915--918",

journal = "Journal of Medical Virology",

issn = "0146-6615",

publisher = "Wiley-Liss Inc.",

number = "5",

}

TY - JOUR

T1 - The use of human sewage screening for community surveillance of hepatitis E virus in the UK

AU - Smith, Donald B

AU - Paddy, Julius O

AU - Simmonds, Peter

PY - 2016/5

Y1 - 2016/5

N2 - Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-infected hepatitis patients. This article is protected by copyright. All rights reserved.

AB - Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-infected hepatitis patients. This article is protected by copyright. All rights reserved.

U2 - 10.1002/jmv.24403

DO - 10.1002/jmv.24403

M3 - Article

C2 - 26461450

SN - 0146-6615

VL - 88

SP - 915

EP - 918

JO - Journal of Medical Virology

JF - Journal of Medical Virology

IS - 5

ER -

The use of human sewage screening for community surveillance of hepatitis E virus in the UK

Abstract

Access to Document

Fingerprint

Cite this