Methods: We recruited 107 patients with ALS. Normative data were collected on 248 healthy subjects. Participants were administered the ECAS and two standard cognitive screening tools (FAB; MoCA), two psychological questionnaires (BDI; STAI/Y) and an ad-hoc usability questionnaire. The FBI was also carried out with caregivers.
Results: The ECAS Italian version discriminated well between patients and controls. The most prevalent deficit occurred in executive functions and fluency. Correlations were observed between the ECAS and standard cognitive screening tools and between the ECAS carer interview and the FBI, supporting its full convergent validity.
Conclusions: The ECAS Italian version provides clinicians with a rapid, feasible and sensitive tool, useful to identify different profiles of cognitive-behavioural impairment in ALS.
|Journal||Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration|
|Publication status||Published - 24 May 2016|
- Amyotrophic Lateral Sclerosis (ALS)
- cognitive assessment
- behaviour change