TY - JOUR
T1 - The vasovagal tonus index as a prognostic indicator in dogs with dilated cardiomyopathy
AU - Martinez-Pereira, Yolanda
AU - Woolley, R.
AU - Culshaw, G.
AU - French, A.
AU - Martin, M.
N1 - WOS:000260539600006
Times Cited: 1
PY - 2008/11
Y1 - 2008/11
N2 - OBJECTIVES: To investigate the prognostic and diagnostic value of heart rate variability (HRV) using the vasovagal tonus index (VVTI) in dogs suffering from idiopathic dilated cardiomyopathy (DCM). METHODS: Electrocardiographic (ECG) recordings of 369 patients presented to a referral centre between 1993 and 2006 were reviewed. RESULTS: VVTI values were calculated from 132 dogs. Lower VVTI values were found in patients in International Small Animal Cardiac Health Council (ISACHC) heart failure (HF) class 2 and 3 compared with class 1. VVTI was found to be positively correlated with survival time (ST) in class 2 and 3 patients. When a cut-off value of 7 center dot 59 for VVTI was used, the test could differentiate patients in ISACHC HF class 1 versus 2 and 3 with a sensitivity of 89 per cent and a specificity of 62 center dot 5 per cent. The ST for patients with VVTI values less than 7 center dot 59 was significantly lower. CLINICAL SIGNIFICANCE: The VVTI is a useful index, obtained from a standard ECG recording that estimates HRV in dogs and does not require any specific equipment for its calculation. It can be useful as a diagnostic tool to assess the severity of HF and is a useful prognostic tool in dogs with DCM.
AB - OBJECTIVES: To investigate the prognostic and diagnostic value of heart rate variability (HRV) using the vasovagal tonus index (VVTI) in dogs suffering from idiopathic dilated cardiomyopathy (DCM). METHODS: Electrocardiographic (ECG) recordings of 369 patients presented to a referral centre between 1993 and 2006 were reviewed. RESULTS: VVTI values were calculated from 132 dogs. Lower VVTI values were found in patients in International Small Animal Cardiac Health Council (ISACHC) heart failure (HF) class 2 and 3 compared with class 1. VVTI was found to be positively correlated with survival time (ST) in class 2 and 3 patients. When a cut-off value of 7 center dot 59 for VVTI was used, the test could differentiate patients in ISACHC HF class 1 versus 2 and 3 with a sensitivity of 89 per cent and a specificity of 62 center dot 5 per cent. The ST for patients with VVTI values less than 7 center dot 59 was significantly lower. CLINICAL SIGNIFICANCE: The VVTI is a useful index, obtained from a standard ECG recording that estimates HRV in dogs and does not require any specific equipment for its calculation. It can be useful as a diagnostic tool to assess the severity of HF and is a useful prognostic tool in dogs with DCM.
UR - http://www.scopus.com/inward/record.url?scp=55349096833&partnerID=8YFLogxK
U2 - 10.1111/j.1748-5827.2008.00654.x
DO - 10.1111/j.1748-5827.2008.00654.x
M3 - Article
C2 - 19006490
SN - 0022-4510
VL - 49
SP - 587
EP - 592
JO - Journal of Small Animal Practice
JF - Journal of Small Animal Practice
IS - 11
ER -