The vasovagal tonus index as a prognostic indicator in dogs with dilated cardiomyopathy

Yolanda Martinez-Pereira, R. Woolley, G. Culshaw, A. French, M. Martin

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: To investigate the prognostic and diagnostic value of heart rate variability (HRV) using the vasovagal tonus index (VVTI) in dogs suffering from idiopathic dilated cardiomyopathy (DCM). METHODS: Electrocardiographic (ECG) recordings of 369 patients presented to a referral centre between 1993 and 2006 were reviewed. RESULTS: VVTI values were calculated from 132 dogs. Lower VVTI values were found in patients in International Small Animal Cardiac Health Council (ISACHC) heart failure (HF) class 2 and 3 compared with class 1. VVTI was found to be positively correlated with survival time (ST) in class 2 and 3 patients. When a cut-off value of 7 center dot 59 for VVTI was used, the test could differentiate patients in ISACHC HF class 1 versus 2 and 3 with a sensitivity of 89 per cent and a specificity of 62 center dot 5 per cent. The ST for patients with VVTI values less than 7 center dot 59 was significantly lower. CLINICAL SIGNIFICANCE: The VVTI is a useful index, obtained from a standard ECG recording that estimates HRV in dogs and does not require any specific equipment for its calculation. It can be useful as a diagnostic tool to assess the severity of HF and is a useful prognostic tool in dogs with DCM.
Original languageEnglish
Pages (from-to)587-592
Number of pages6
JournalJournal of Small Animal Practice
Volume49
Issue number11
DOIs
Publication statusPublished - Nov 2008

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