Three-dimensional representation software as image enhancement tool in small-bowel capsule endoscopy: A feasibility study

Anastasios Koulaouzidis*, Alexandros Karargyris, Emanuele Rondonotti, Colin L. Noble, Sarah Douglas, Efstratios Alexandridis, Ali M. Zahid, Andrew J. Bathgate, Ken C. Trimble, John N. Plevris

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Three-dimensional imaging in capsule endoscopy is not currently feasible due to hardware limitations. However, software algorithms that enable three-dimensional reconstruction in capsule endoscopy are available.

Methods: Feasibility study. A phantom was designed to test the accuracy of three-dimensional reconstruction. Thereafter, 192 small-bowel capsule endoscopy images (of vascular: 50; inflammatory: 73; protruding structures: 69) were reviewed with the aid of a purpose-built three-dimensional reconstruction software. Seven endoscopists rated visualisation improved or non-improved. Subgroup analyses performed for diagnostic category, diagnosis, image surface morphology and colour and SBCE equipment used (PillCam (R) vs. MiroCam (R)).

Results: Overall, phantom experiments showed that the three-dimensional reconstruction software was accurate at 90% of red, 70% of yellow and 45% of white phantom models. Enhanced visualisation for 56% of vascular, 23% of inflammatory and

Conclusions: Application of a three-dimensional reconstruction software in capsule endoscopy leads to image enhancement for a significant proportion of vascular, but less so for inflammatory and protruding lesions. Until optics technology allows hardware-enabled three-dimensional reconstruction, it seems a plausible alternative. Crown Copyright (C) 2013 Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l. All rights reserved.

Original languageEnglish
Pages (from-to)909-914
Number of pages6
JournalDigestive and Liver Disease
Issue number11
Publication statusPublished - Nov 2013


  • Capsule endoscopy
  • Enhancement
  • Feasibility
  • Inflammatory
  • Polyps
  • Reconstruction
  • Small-bowel
  • Software
  • Three-dimensional
  • Vascular


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