Thyroid hormone signaling in human ovarian surface epithelial cells

M T Rae, O Gubbay, A Kostogiannou, D Price, H O D Critchley, S G Hillier

Research output: Contribution to journalArticlepeer-review

Abstract

Ovarian surface epithelial (OSE) cells express multiple nuclear hormone receptor genes, including those encoding thyroid hormone and estrogen receptors (TR and ER, respectively). Ovarian cancer is hormone-dependent, and epidemiological evidence links hyperthyroidism, inflammation of the ovarian surface, and increased risk of ovarian cancer.
Original languageEnglish
Pages (from-to)322-7
Number of pages6
JournalJournal of Clinical Endocrinology & Metabolism
Volume92
Issue number1
DOIs
Publication statusPublished - 2007

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