Time-dependent behaviour of demineralised trabecular bone – experimental investigation and development of a constitutive model

Trabecular bone is a cellular composite material comprising primarily of mineral and organic phases and its mechanical response to loads is time-dependent. The contribution of the organic phase to the time-dependent behaviour of bone is not yet understood. We investigated the time-dependent response of demineralised trabecular bone through tensile multiple-load-creep-unload-recovery experiments. We found that demineralised trabecular bone’s time-dependent response is nonlinearly related to the applied stress levels - it stiffens with increased stress levels. Our results also indicated that the time-dependent behaviour is associated with the original bone volume ratio (BV/TV). Irrecoverable strain exists, even at the low strain levels, but are not associated with BV/TV. Furthermore, we found that the nonlinear viscoelastic model can accurately predict the time dependent behaviour of the trabecular bone’s organic phase, which can be incorporated together with the properties of mineral to generate a composite model of bone. This study will help to provide a better understanding of this natural composite material.