Time dependent behaviour of trabecular bone at multiple load levels

Shuqiao Xie; Krishnagoud Manda; Robert Wallace; Francesc Levrero florencio; Hamish Simpson; Pankaj Pankaj

doi:10.1007/s10439-017-1800-1

Time dependent behaviour of trabecular bone at multiple load levels

Shuqiao Xie, Krishnagoud Manda, Robert Wallace, Francesc Levrero florencio, Hamish Simpson, Pankaj Pankaj^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The deformation of bone when subjected to loads is not instantaneous but varies with time. To investigate this time-dependent behaviour sixteen bovine trabecular bone specimens were subjected to compressive loading, creep, unloading and recovery at multiple load levels corresponding to apparent strains of 2000–25,000 με. We found that: the time-dependent response of trabecular bone comprises of both recoverable and irrecoverable strains; the strain response is nonlinearly related to applied load levels; and the response is linked to bone volume fraction. Although majority of strain is recovered after the load-creep-unload-recovery cycle some residual strain always exists. The analysis of results indicates that trabecular bone becomes stiffer initially and then experiences stiffness degradation with the increasing load levels. Steady state creep rate was found to be dependent on applied stress level and bone volume fraction with a power law relationship.

Original language	English
Pages (from-to)	1219-1226
Number of pages	8
Journal	Annals of Biomedical Engineering
Volume	45
Issue number	5
Early online date	27 Jan 2017
DOIs	https://doi.org/10.1007/s10439-017-1800-1
Publication status	Published - 1 May 2017

Keywords / Materials (for Non-textual outputs)

Creep-recovery
Viscoelastic
Bone volume fraction
Steady state creep rate
Creep compliance
HUMAN CANCELLOUS BONE
FATIGUE BEHAVIOR
MECHANICAL-PROPERTIES
VERTEBRAL DEFORMITY
MINERAL DENSITY
CORTICAL BONE
FEMORAL-HEAD
CREEP
STRAINS

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10.1007/s10439-017-1800-1

art%3A10.1007%2Fs10439-017-1800-1Final published version, 1.24 MB

A novel diagnostic tool: from structural health monitoring to tissue quality prediction
Pankaj, P.
Other
1/10/13 → 31/03/17
Project: Research

Characterisation of time-dependent mechanical behaviour of trabecular bone samples
Pankaj, P. (Creator) & Xie, S. (Creator), Edinburgh DataShare, 18 Apr 2018
DOI: 10.7488/ds/2340
Dataset

Cite this

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title = "Time dependent behaviour of trabecular bone at multiple load levels",

abstract = "The deformation of bone when subjected to loads is not instantaneous but varies with time. To investigate this time-dependent behaviour sixteen bovine trabecular bone specimens were subjected to compressive loading, creep, unloading and recovery at multiple load levels corresponding to apparent strains of 2000–25,000 με. We found that: the time-dependent response of trabecular bone comprises of both recoverable and irrecoverable strains; the strain response is nonlinearly related to applied load levels; and the response is linked to bone volume fraction. Although majority of strain is recovered after the load-creep-unload-recovery cycle some residual strain always exists. The analysis of results indicates that trabecular bone becomes stiffer initially and then experiences stiffness degradation with the increasing load levels. Steady state creep rate was found to be dependent on applied stress level and bone volume fraction with a power law relationship.",

keywords = "Creep-recovery, Viscoelastic, Bone volume fraction, Steady state creep rate, Creep compliance, HUMAN CANCELLOUS BONE, FATIGUE BEHAVIOR, MECHANICAL-PROPERTIES, VERTEBRAL DEFORMITY, MINERAL DENSITY, CORTICAL BONE, FEMORAL-HEAD, CREEP, STRAINS",

author = "Shuqiao Xie and Krishnagoud Manda and Robert Wallace and {Levrero florencio}, Francesc and Hamish Simpson and Pankaj Pankaj",

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TY - JOUR

T1 - Time dependent behaviour of trabecular bone at multiple load levels

AU - Xie, Shuqiao

AU - Manda, Krishnagoud

AU - Wallace, Robert

AU - Levrero florencio, Francesc

AU - Simpson, Hamish

AU - Pankaj, Pankaj

N1 - Springer Compact Gold OA

PY - 2017/5/1

Y1 - 2017/5/1

N2 - The deformation of bone when subjected to loads is not instantaneous but varies with time. To investigate this time-dependent behaviour sixteen bovine trabecular bone specimens were subjected to compressive loading, creep, unloading and recovery at multiple load levels corresponding to apparent strains of 2000–25,000 με. We found that: the time-dependent response of trabecular bone comprises of both recoverable and irrecoverable strains; the strain response is nonlinearly related to applied load levels; and the response is linked to bone volume fraction. Although majority of strain is recovered after the load-creep-unload-recovery cycle some residual strain always exists. The analysis of results indicates that trabecular bone becomes stiffer initially and then experiences stiffness degradation with the increasing load levels. Steady state creep rate was found to be dependent on applied stress level and bone volume fraction with a power law relationship.

AB - The deformation of bone when subjected to loads is not instantaneous but varies with time. To investigate this time-dependent behaviour sixteen bovine trabecular bone specimens were subjected to compressive loading, creep, unloading and recovery at multiple load levels corresponding to apparent strains of 2000–25,000 με. We found that: the time-dependent response of trabecular bone comprises of both recoverable and irrecoverable strains; the strain response is nonlinearly related to applied load levels; and the response is linked to bone volume fraction. Although majority of strain is recovered after the load-creep-unload-recovery cycle some residual strain always exists. The analysis of results indicates that trabecular bone becomes stiffer initially and then experiences stiffness degradation with the increasing load levels. Steady state creep rate was found to be dependent on applied stress level and bone volume fraction with a power law relationship.

KW - Creep-recovery

KW - Viscoelastic

KW - Bone volume fraction

KW - Steady state creep rate

KW - Creep compliance

KW - HUMAN CANCELLOUS BONE

KW - FATIGUE BEHAVIOR

KW - MECHANICAL-PROPERTIES

KW - VERTEBRAL DEFORMITY

KW - MINERAL DENSITY

KW - CORTICAL BONE

KW - FEMORAL-HEAD

KW - CREEP

KW - STRAINS

U2 - 10.1007/s10439-017-1800-1

DO - 10.1007/s10439-017-1800-1

M3 - Article

SN - 0090-6964

VL - 45

SP - 1219

EP - 1226

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

IS - 5

ER -

Time dependent behaviour of trabecular bone at multiple load levels

Abstract

Keywords / Materials (for Non-textual outputs)

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A novel diagnostic tool: from structural health monitoring to tissue quality prediction

Datasets

Characterisation of time-dependent mechanical behaviour of trabecular bone samples

Cite this