We present a new program (iHixs) which computes the inclusive Higgs boson cross-section at hadron colliders. It incorporates QCD corrections through NNLO, real and virtual electroweak corrections, mixed QCD-electroweak corrections, quark-mass effects through NLO in QCD, and finite width effects for the Higgs boson and heavy quarks. iHixs can be used to obtain the most precise cross-section values in fixed order perturbation theory in the Standard Model. In addition, it allows for a consistent evaluation of the cross-section in modified Higgs boson sectors with anomalous Yukawa and electroweak interactions as required in extensions of the Standard Model. iHixs is interfaced with the LHAPDF library and can be used with all available NNLO sets of parton distribution functions.