Towards a smartphone-aided electronic ELISA for real-time electrochemical monitoring

Nikolaos G. Pechlivanidis, Konstantinos I. Papadimitriou, Daniel Evans, Nikolaos Vasilakis, Themistoklis Prodromakis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract / Description of output

This paper details the design and fabrication of a portable, smartphone-integrated electronic platform, tailored to read-out electronic ELISA (eELISA) data from printed circuit board (PCB)-based sensors. The instrument features eight independent, re-configurable current input channels, each consisting of a low-noise transimpedance amplifier (TIA) and filtering stage coupled to low-noise switch ICs for automatic current range detection. A bipolar, 16-bit resolution voltage-input analog-to-digital converter (ADC) has been employed for digitisation of converted current values received from the analogue front-end. In addition, a bipolar, 12-bit resolution digital-to-analog converter (DAC) combined with standard three-electrode potentiostats provides wide range biasing voltages to the amperometric sensors. The resulting digital data is transmitted via serial interface to an Android-based smartphone, where an ergonomic user interface guides the operator through the detection process. The customised Android application (App) provides real-time monitoring of the electrochemical cell and stores returned biochemical data on the device once measurement is complete.

Original languageEnglish
Title of host publicationIEEE International Symposium on Circuits and Systems
Subtitle of host publicationFrom Dreams to Innovation, ISCAS 2017 - Conference Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781467368520
DOIs
Publication statusPublished - 28 Sept 2017
Event50th IEEE International Symposium on Circuits and Systems, ISCAS 2017 - Baltimore, United States
Duration: 28 May 201731 May 2017

Publication series

NameProceedings - IEEE International Symposium on Circuits and Systems
ISSN (Print)0271-4310

Conference

Conference50th IEEE International Symposium on Circuits and Systems, ISCAS 2017
Country/TerritoryUnited States
CityBaltimore
Period28/05/1731/05/17

Keywords / Materials (for Non-textual outputs)

  • Amperometry
  • Analog-to-Digital Conversion
  • Bioin-strumentation
  • eELISA
  • Lab-on-PCB
  • Smartphone-Aided

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