Towards system level modeling of functional modules and regulatory pathways using genome-scale data

Tom Michoel; Anagha Joshi; Eric Bonnet; Vanessa Vermeirssen; Yves Van de Peer

Towards system level modeling of functional modules and regulatory pathways using genome-scale data

Tom Michoel, Anagha Joshi, Eric Bonnet, Vanessa Vermeirssen, Yves Van de Peer

Royal (Dick) School of Veterinary Studies

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract / Description of output

Understanding complex biological processes such as development
and pathology of multicellular organisms at a
system level requires the study of dynamic networks of interacting
molecules. High-throughput methods have generated
large-scale, static networks of physical interactions
which may occur or not depending on spatial, temporal
or context-specific variation, while genome-wide microarray
datasets measure the functional state of a cell precisely
under such varying conditions. Here we present
recent results towards integrative, system level modeling
of functional modules and regulatory pathways using diverse
genome-scale data.

Original language	English
Title of host publication	Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg
Editors	Matti Nykter, Pekka Ruusuvuori, Carsten Carlberg, Olli Yli-Harja
Place of Publication	Tampere
Publisher	Tampere International Center for Signal Processing
Pages	71-74
ISBN (Print)	978-952-15-2384-7
Publication status	Published - 2010
Event	Seventh International Workshop on Computational Systems Biology - Luxembourg, Luxembourg Duration: 16 Jun 2010 → 18 Jun 2010

Publication series

Name	TICSP Series
Publisher	Tampere International Center for Signal Processing
Number	51

Conference

Conference	Seventh International Workshop on Computational Systems Biology
Country/Territory	Luxembourg
City	Luxembourg
Period	16/06/10 → 18/06/10

Access to Document

http://www.cs.tut.fi/wcsb10/index.html

Cite this

Michoel, T., Joshi, A., Bonnet, E., Vermeirssen, V., & Van de Peer, Y. (2010). Towards system level modeling of functional modules and regulatory pathways using genome-scale data. In M. Nykter, P. Ruusuvuori, C. Carlberg, & O. Yli-Harja (Eds.), Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg (pp. 71-74). (TICSP Series; No. 51). Tampere International Center for Signal Processing. http://www.cs.tut.fi/wcsb10/index.html

Michoel, Tom ; Joshi, Anagha ; Bonnet, Eric et al. / Towards system level modeling of functional modules and regulatory pathways using genome-scale data. Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg. editor / Matti Nykter ; Pekka Ruusuvuori ; Carsten Carlberg ; Olli Yli-Harja. Tampere : Tampere International Center for Signal Processing, 2010. pp. 71-74 (TICSP Series; 51).

@inproceedings{68a23dddd94444429d2fc67bcdde434f,

title = "Towards system level modeling of functional modules and regulatory pathways using genome-scale data",

abstract = "Understanding complex biological processes such as development and pathology of multicellular organisms at a system level requires the study of dynamic networks of interacting molecules. High-throughput methods have generated large-scale, static networks of physical interactions which may occur or not depending on spatial, temporal or context-specific variation, while genome-wide microarray datasets measure the functional state of a cell precisely under such varying conditions. Here we present recent results towards integrative, system level modeling of functional modules and regulatory pathways using diverse genome-scale data.",

author = "Tom Michoel and Anagha Joshi and Eric Bonnet and Vanessa Vermeirssen and {Van de Peer}, Yves",

year = "2010",

language = "English",

isbn = "978-952-15-2384-7",

series = "TICSP Series",

publisher = "Tampere International Center for Signal Processing",

number = "51",

pages = "71--74",

editor = "Nykter, {Matti } and Ruusuvuori, {Pekka } and Carlberg, {Carsten } and Yli-Harja, {Olli }",

booktitle = "Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg",

note = "Seventh International Workshop on Computational Systems Biology ; Conference date: 16-06-2010 Through 18-06-2010",

}

Michoel, T, Joshi, A, Bonnet, E, Vermeirssen, V & Van de Peer, Y 2010, Towards system level modeling of functional modules and regulatory pathways using genome-scale data. in M Nykter, P Ruusuvuori, C Carlberg & O Yli-Harja (eds), Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg. TICSP Series, no. 51, Tampere International Center for Signal Processing, Tampere, pp. 71-74, Seventh International Workshop on Computational Systems Biology, Luxembourg, Luxembourg, 16/06/10. <http://www.cs.tut.fi/wcsb10/index.html>

Towards system level modeling of functional modules and regulatory pathways using genome-scale data. / Michoel, Tom; Joshi, Anagha; Bonnet, Eric et al.
Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg. ed. / Matti Nykter; Pekka Ruusuvuori; Carsten Carlberg; Olli Yli-Harja. Tampere: Tampere International Center for Signal Processing, 2010. p. 71-74 (TICSP Series; No. 51).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Towards system level modeling of functional modules and regulatory pathways using genome-scale data

AU - Michoel, Tom

AU - Joshi, Anagha

AU - Bonnet, Eric

AU - Vermeirssen, Vanessa

AU - Van de Peer, Yves

PY - 2010

Y1 - 2010

N2 - Understanding complex biological processes such as development and pathology of multicellular organisms at a system level requires the study of dynamic networks of interacting molecules. High-throughput methods have generated large-scale, static networks of physical interactions which may occur or not depending on spatial, temporal or context-specific variation, while genome-wide microarray datasets measure the functional state of a cell precisely under such varying conditions. Here we present recent results towards integrative, system level modeling of functional modules and regulatory pathways using diverse genome-scale data.

AB - Understanding complex biological processes such as development and pathology of multicellular organisms at a system level requires the study of dynamic networks of interacting molecules. High-throughput methods have generated large-scale, static networks of physical interactions which may occur or not depending on spatial, temporal or context-specific variation, while genome-wide microarray datasets measure the functional state of a cell precisely under such varying conditions. Here we present recent results towards integrative, system level modeling of functional modules and regulatory pathways using diverse genome-scale data.

M3 - Conference contribution

SN - 978-952-15-2384-7

T3 - TICSP Series

SP - 71

EP - 74

BT - Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg

A2 - Nykter, Matti

A2 - Ruusuvuori, Pekka

A2 - Carlberg, Carsten

A2 - Yli-Harja, Olli

PB - Tampere International Center for Signal Processing

CY - Tampere

T2 - Seventh International Workshop on Computational Systems Biology

Y2 - 16 June 2010 through 18 June 2010

ER -

Michoel T, Joshi A, Bonnet E, Vermeirssen V, Van de Peer Y. Towards system level modeling of functional modules and regulatory pathways using genome-scale data. In Nykter M, Ruusuvuori P, Carlberg C, Yli-Harja O, editors, Seventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg. Tampere: Tampere International Center for Signal Processing. 2010. p. 71-74. (TICSP Series; 51).

Towards system level modeling of functional modules and regulatory pathways using genome-scale data

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Publication series

Conference

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Cite this