Towards system level modeling of functional modules and regulatory pathways using genome-scale data

Tom Michoel, Anagha Joshi, Eric Bonnet, Vanessa Vermeirssen, Yves Van de Peer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Understanding complex biological processes such as development
and pathology of multicellular organisms at a
system level requires the study of dynamic networks of interacting
molecules. High-throughput methods have generated
large-scale, static networks of physical interactions
which may occur or not depending on spatial, temporal
or context-specific variation, while genome-wide microarray
datasets measure the functional state of a cell precisely
under such varying conditions. Here we present
recent results towards integrative, system level modeling
of functional modules and regulatory pathways using diverse
genome-scale data.
Original languageEnglish
Title of host publicationSeventh International Workshop on Computational Systems Biology, WCSB 2010, June 16–18, 2010, Luxembourg
EditorsMatti Nykter, Pekka Ruusuvuori, Carsten Carlberg, Olli Yli-Harja
Place of PublicationTampere
PublisherTampere International Center for Signal Processing
Pages71-74
ISBN (Print)978-952-15-2384-7
Publication statusPublished - 2010
EventSeventh International Workshop on Computational Systems Biology - Luxembourg, Luxembourg
Duration: 16 Jun 201018 Jun 2010

Publication series

NameTICSP Series
PublisherTampere International Center for Signal Processing
Number51

Conference

ConferenceSeventh International Workshop on Computational Systems Biology
CountryLuxembourg
CityLuxembourg
Period16/06/1018/06/10

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