Transcutaneous oxygen levels in retinopathy of prematurity

S Cunningham, B W Fleck, R A Elton, N McIntosh

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Retinopathy of prematurity (ROP) is a potentially blinding disease of preterm infants. 21 days of computer-recorded transcutaneous oxygen (TcPO2) data were compared in 31 infants with stage 3 or greater ROP and 38 infants with no ROP or stage 1 or 2. In a multiple logistic regression adjusted for significant perinatal factors (birthweight, gestation, and intraventricular haemorrhage), babies with stage 3 or higher ROP showed an increased variability of TcPO2 in week 1 (p < 0.01) and 2 (p = 0.012) but not week 3. Variability of TcPO2 in the first 2 weeks of life is a significant predictor of severe ROP.

Original languageEnglish
Pages (from-to)1464-5
Number of pages2
JournalThe Lancet
Volume346
Issue number8988
Publication statusPublished - 2 Dec 1995

Keywords / Materials (for Non-textual outputs)

  • Blood Gas Monitoring, Transcutaneous
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Logistic Models
  • Male
  • Predictive Value of Tests
  • Retinopathy of Prematurity

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