Transient cycloheximide resistance in a tobacco cell line

P Maliga, G Lázár, Z Sváb, F Nagy

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Cylcoheximide-resistant cell lines have been recovered from tissue cultures of haploid Nicotiana tabacum at the usual mutant frequency (10(-6)). One such line, CR 4/6 was studied in detail. Resistance is based on the potential of the callus to inactive cycloheximide. The transient nature of the resistance and its association with differentiated cells indicate that the new phenotype is not due to a mutation, but rather to an alteration in gene expression.
Original languageEnglish
Pages (from-to)267-71
Number of pages5
JournalMolecular and General Genetics MGG
Issue number3
Publication statusPublished - 1976

Keywords / Materials (for Non-textual outputs)

  • gene expression
  • tissue culture
  • Cycloheximide
  • mutant frequency
  • tobacco cell


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