Transition of mesenchymal stem/stromal cells to endothelial cells

Research output: Contribution to journalComment/debate

Abstract

Mesenchymal stem/stromal cells (MSCs) are heterogeneous. A fraction of these cells constitute multipotent cells that can self-renew and mainly give rise to mesodermal lineage cells such as adipocytes, osteocytes and chondrocytes. The ability of MSCs to differentiate into endothelial cells remains controversial. Isolation and in vitro manipulation of MSCs before clinical application are important steps. High numbers of MSCs are needed, requiring the in vitro expansion of these clinically important cells. To this end, a well-controlled procedure for MSC isolation and maintenance in culture is necessary.

Original languageEnglish
Pages (from-to)95
JournalCurrent stem cell research & therapy
Volume4
Issue number4
DOIs
Publication statusPublished - 2013

Keywords

  • Cell Culture Techniques
  • Endothelial Cells
  • Humans
  • Mesenchymal Stromal Cells
  • Umbilical Cord

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