Abstract / Description of output
Purpose of review
The epidemiology of hepatitis C virus (HCV) in HIV has changed significantly over the past decade. This review will outline the current epidemiology of HCV in HIV infection, focusing on the recent changes and factors which have been related to the increase in HCV transmission in HIV-infected men who have sex with men (MSM).
Recent findings
Since 2000 there has been recognition in the postindustrialized world that there has been a dramatic rise in the incidence of HCV in HIV-infected MSM. Whereas sexual transmission of HCV remains controversial in the general population, there is increasing evidence that permucosal (sexual and mucosally administered drugs) rather than parenteral risks have become key factors in HCV transmission in HIV-infected MSM. At the most basic level, transmission depends on disruption of a barrier and exposure to infected fluids, usually blood. Whereas transmission factors are often closely entwined, they can be characterized as behavioural and biological factors.
Summary
With an improved understanding of the epidemiology of HCV in this population, interventions by relevant health authorities could be better focused.
The epidemiology of hepatitis C virus (HCV) in HIV has changed significantly over the past decade. This review will outline the current epidemiology of HCV in HIV infection, focusing on the recent changes and factors which have been related to the increase in HCV transmission in HIV-infected men who have sex with men (MSM).
Recent findings
Since 2000 there has been recognition in the postindustrialized world that there has been a dramatic rise in the incidence of HCV in HIV-infected MSM. Whereas sexual transmission of HCV remains controversial in the general population, there is increasing evidence that permucosal (sexual and mucosally administered drugs) rather than parenteral risks have become key factors in HCV transmission in HIV-infected MSM. At the most basic level, transmission depends on disruption of a barrier and exposure to infected fluids, usually blood. Whereas transmission factors are often closely entwined, they can be characterized as behavioural and biological factors.
Summary
With an improved understanding of the epidemiology of HCV in this population, interventions by relevant health authorities could be better focused.
Original language | English |
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Pages (from-to) | 451-458 |
Number of pages | 8 |
Journal | CURRENT OPINION IN HIV AND AIDS |
Volume | 6 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Nov 2011 |
Keywords / Materials (for Non-textual outputs)
- Science & Technology
- Life Sciences & Biomedicine
- Immunology
- Infectious Diseases
- acute hepatitis C
- co-infection
- epidemiology
- hepatitis C virus
- HIV
- transmission
- HEPATITIS-C VIRUS
- SEXUAL TRANSMISSION
- HOMOSEXUAL-MEN
- INFECTED MEN
- PROSPECTIVE COHORT
- SUBSTANCE USE
- INCREASE
- EPIDEMIC
- RISK
- MSM