Transmission rates of hepatitis C virus by different batches of a contaminated anti-D immunoglobulin preparation

E Lawlor, J Power, J Garson, P Yap, F Davidson, G Columb, D Smith, L Pomeroy, J O'Riordan, P Simmonds, R Tedder

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to determine the hepatitis C virus (HCV) infection rate of recipients of different batches of anti-D immunoglobulin associated with an outbreak of HCV infection which occurred in 1977 and its relationship to the polymerase chain reaction (PCR) status of the implicated batches. This study was undertaken to determine the predictive value of HCV genome detection and quantification for subsequent infection in recipients of an HCV-contaminated anti-D immunoglobulin product for intravenous use.
Original languageEnglish
Pages (from-to)138-43
Number of pages6
JournalVox Sanguinis
Volume76
Issue number3
DOIs
Publication statusPublished - 1999

Keywords

  • Disease Outbreaks
  • Female
  • Follow-Up Studies
  • Genome, Viral
  • Hepacivirus
  • Hepatitis C
  • Humans
  • Ireland
  • Polymerase Chain Reaction
  • Rho(D) Immune Globulin

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