Twenty four-hour helpline access to expert management advice for food-allergy-triggered anaphylaxis in infants, children and young people: a pragmatic, randomized controlled trial

M. M. Kelleher; A. DunnGalvin; A. Sheikh; C. Cullinane; J. Fitzsimons; J. O'B. Hourihane

doi:10.1111/all.12310

Twenty four-hour helpline access to expert management advice for food-allergy-triggered anaphylaxis in infants, children and young people: a pragmatic, randomized controlled trial

M. M. Kelleher, A. DunnGalvin, A. Sheikh, C. Cullinane, J. Fitzsimons, J. O'B. Hourihane^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

BackgroundAnaphylaxis is a life-threatening emergency. If promptly administered, adrenaline is potentially life-saving. Many food-allergic-children/carers are unsure when to use their adrenaline autoinjectors, contributing to a low quality of life and worse outcomes in the setting of an acute allergic reaction.

ObjectivesThe aim of this study was to assess the effectiveness of 24-hour telephone access to specialist clinical advice on disease-specific quality of life.

MethodsA pragmatic two-arm, parallel-group randomized control trial was conducted. Children/carers (

ResultsFifty two children/carers were recruited. FAQL scores remained static in the control group across the three time points. Scores gradually improved in the intervention group, with a significant difference seen at 6months (T1-T3 Mean difference=-1.5, (CI 0.87-2.25) P

ConclusionThe 24-hour helpline improved food-allergy-specific quality of life in children. Six-month intervention support resulted in sustained benefits for at least a further 6months.

Original language	English
Pages (from-to)	1598-1604
Number of pages	7
Journal	Allergy
Volume	68
Issue number	12
DOIs	https://doi.org/10.1111/all.12310
Publication status	Published - 5 Dec 2013

Keywords / Materials (for Non-textual outputs)

adrenaline
anaphylaxis
food allergy
paediatrics
quality of life
QUALITY-OF-LIFE
QUESTIONNAIRE
EPINEPHRINE
ADOLESCENTS
GUIDELINES
CHILDHOOD
EMERGENCY
VALIDITY
EPIPEN
IMPACT

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@article{e8207329ca384cbba9df315d325ae457,

title = "Twenty four-hour helpline access to expert management advice for food-allergy-triggered anaphylaxis in infants, children and young people: a pragmatic, randomized controlled trial",

abstract = "BackgroundAnaphylaxis is a life-threatening emergency. If promptly administered, adrenaline is potentially life-saving. Many food-allergic-children/carers are unsure when to use their adrenaline autoinjectors, contributing to a low quality of life and worse outcomes in the setting of an acute allergic reaction.ObjectivesThe aim of this study was to assess the effectiveness of 24-hour telephone access to specialist clinical advice on disease-specific quality of life.MethodsA pragmatic two-arm, parallel-group randomized control trial was conducted. Children/carers (ResultsFifty two children/carers were recruited. FAQL scores remained static in the control group across the three time points. Scores gradually improved in the intervention group, with a significant difference seen at 6months (T1-T3 Mean difference=-1.5, (CI 0.87-2.25) PConclusionThe 24-hour helpline improved food-allergy-specific quality of life in children. Six-month intervention support resulted in sustained benefits for at least a further 6months.",

keywords = "adrenaline, anaphylaxis, food allergy, paediatrics, quality of life, QUALITY-OF-LIFE, QUESTIONNAIRE, EPINEPHRINE, ADOLESCENTS, GUIDELINES, CHILDHOOD, EMERGENCY, VALIDITY, EPIPEN, IMPACT",

author = "Kelleher, \{M. M.\} and A. DunnGalvin and A. Sheikh and C. Cullinane and J. Fitzsimons and Hourihane, \{J. O'B.\}",

year = "2013",

month = dec,

day = "5",

doi = "10.1111/all.12310",

language = "English",

volume = "68",

pages = "1598--1604",

journal = "Allergy",

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publisher = "Wiley-Blackwell",

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TY - JOUR

T1 - Twenty four-hour helpline access to expert management advice for food-allergy-triggered anaphylaxis in infants, children and young people: a pragmatic, randomized controlled trial

AU - Kelleher, M. M.

AU - DunnGalvin, A.

AU - Sheikh, A.

AU - Cullinane, C.

AU - Fitzsimons, J.

AU - Hourihane, J. O'B.

PY - 2013/12/5

Y1 - 2013/12/5

N2 - BackgroundAnaphylaxis is a life-threatening emergency. If promptly administered, adrenaline is potentially life-saving. Many food-allergic-children/carers are unsure when to use their adrenaline autoinjectors, contributing to a low quality of life and worse outcomes in the setting of an acute allergic reaction.ObjectivesThe aim of this study was to assess the effectiveness of 24-hour telephone access to specialist clinical advice on disease-specific quality of life.MethodsA pragmatic two-arm, parallel-group randomized control trial was conducted. Children/carers (ResultsFifty two children/carers were recruited. FAQL scores remained static in the control group across the three time points. Scores gradually improved in the intervention group, with a significant difference seen at 6months (T1-T3 Mean difference=-1.5, (CI 0.87-2.25) PConclusionThe 24-hour helpline improved food-allergy-specific quality of life in children. Six-month intervention support resulted in sustained benefits for at least a further 6months.

AB - BackgroundAnaphylaxis is a life-threatening emergency. If promptly administered, adrenaline is potentially life-saving. Many food-allergic-children/carers are unsure when to use their adrenaline autoinjectors, contributing to a low quality of life and worse outcomes in the setting of an acute allergic reaction.ObjectivesThe aim of this study was to assess the effectiveness of 24-hour telephone access to specialist clinical advice on disease-specific quality of life.MethodsA pragmatic two-arm, parallel-group randomized control trial was conducted. Children/carers (ResultsFifty two children/carers were recruited. FAQL scores remained static in the control group across the three time points. Scores gradually improved in the intervention group, with a significant difference seen at 6months (T1-T3 Mean difference=-1.5, (CI 0.87-2.25) PConclusionThe 24-hour helpline improved food-allergy-specific quality of life in children. Six-month intervention support resulted in sustained benefits for at least a further 6months.

KW - adrenaline

KW - anaphylaxis

KW - food allergy

KW - paediatrics

KW - quality of life

KW - QUALITY-OF-LIFE

KW - QUESTIONNAIRE

KW - EPINEPHRINE

KW - ADOLESCENTS

KW - GUIDELINES

KW - CHILDHOOD

KW - EMERGENCY

KW - VALIDITY

KW - EPIPEN

KW - IMPACT

U2 - 10.1111/all.12310

DO - 10.1111/all.12310

M3 - Article

SN - 0105-4538

VL - 68

SP - 1598

EP - 1604

JO - Allergy

JF - Allergy

IS - 12

ER -

Twenty four-hour helpline access to expert management advice for food-allergy-triggered anaphylaxis in infants, children and young people: a pragmatic, randomized controlled trial

Abstract

Keywords / Materials (for Non-textual outputs)

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