Projects per year
Modelling gene regulatory networks in organisms is an important task that has recently become possible due to large scale assays using technologies such as microarrays. In this paper, the circadian clock of Arabidopsis thaliana is modelled by fitting dynamic Bayesian networks to luminescence data gathered from experiments. This work differs from previous modelling attempts by using higher-order dynamic Bayesian networks to explicitly model the time lag between the various genes being expressed. In order to achieve this goal, new techniques in preprocessing the data and in evaluating a learned model are proposed. It is shown that it is possible, to some extent, to model these time delays using a higher-order dynamic Bayesian network.
|Title of host publication||Pattern Recognition in Bioinformatics|
|Subtitle of host publication||4th IAPR International Conference, PRIB 2009, Sheffield, UK, September 7-9, 2009. Proceedings|
|Number of pages||12|
|Publication status||Published - 2009|
|Name||Lecture Notes in Computer Science|
|Publisher||Springer Berlin / Heidelberg|
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- 3 Finished
1/03/08 → 31/08/09
1/03/05 → 30/09/06