Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain

Jean-Philippe Brandel, Craig A Heath, Mark W Head, Etienne Levavasseur, Richard Knight, Jean-Louis Laplanche, Jan Pm Langeveld, James W Ironside, Jean-Jacques Hauw, Jan Mackenzie, Annick Alpérovitch, Robert G Will, Stéphane Haïk

Research output: Contribution to journalArticlepeer-review

Abstract

Variant Creutzfeldt-Jakob disease (vCJD) was first reported in the United Kingdom in 1996. Since then, the majority of cases have been observed in the United Kingdom where there was a major epidemic of bovine spongiform encephalopathy. France was the second country affected. To address the hypothesis of the involvement of a common strain of agent, we have compared clinical, neuropathological, and biochemical data on vCJD patients from both countries.
Original languageEnglish
Pages (from-to)249-56
Number of pages8
JournalAnnals of Neurology
Volume65
Issue number3
DOIs
Publication statusPublished - 2009

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