Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain

Jean-Philippe Brandel; Craig A Heath; Mark W Head; Etienne Levavasseur; Richard Knight; Jean-Louis Laplanche; Jan Pm Langeveld; James W Ironside; Jean-Jacques Hauw; Jan Mackenzie; Annick Alpérovitch; Robert G Will; Stéphane Haïk

doi:10.1002/ana.21583

Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain

Jean-Philippe Brandel, Craig A Heath, Mark W Head, Etienne Levavasseur, Richard Knight, Jean-Louis Laplanche, Jan Pm Langeveld, James W Ironside, Jean-Jacques Hauw, Jan Mackenzie, Annick Alpérovitch, Robert G Will, Stéphane Haïk

Research output: Contribution to journal › Article › peer-review

Abstract

Variant Creutzfeldt-Jakob disease (vCJD) was first reported in the United Kingdom in 1996. Since then, the majority of cases have been observed in the United Kingdom where there was a major epidemic of bovine spongiform encephalopathy. France was the second country affected. To address the hypothesis of the involvement of a common strain of agent, we have compared clinical, neuropathological, and biochemical data on vCJD patients from both countries.

Original language	English
Pages (from-to)	249-56
Number of pages	8
Journal	Annals of Neurology
Volume	65
Issue number	3
DOIs	https://doi.org/10.1002/ana.21583
Publication status	Published - 2009

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Brandel, J.-P., Heath, C. A., Head, M. W., Levavasseur, E., Knight, R., Laplanche, J.-L., Langeveld, J. P., Ironside, J. W., Hauw, J.-J., Mackenzie, J., Alpérovitch, A., Will, R. G., & Haïk, S. (2009). Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain. Annals of Neurology, 65(3), 249-56. https://doi.org/10.1002/ana.21583

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abstract = "Variant Creutzfeldt-Jakob disease (vCJD) was first reported in the United Kingdom in 1996. Since then, the majority of cases have been observed in the United Kingdom where there was a major epidemic of bovine spongiform encephalopathy. France was the second country affected. To address the hypothesis of the involvement of a common strain of agent, we have compared clinical, neuropathological, and biochemical data on vCJD patients from both countries.",

author = "Jean-Philippe Brandel and Heath, \{Craig A\} and Head, \{Mark W\} and Etienne Levavasseur and Richard Knight and Jean-Louis Laplanche and Langeveld, \{Jan Pm\} and Ironside, \{James W\} and Jean-Jacques Hauw and Jan Mackenzie and Annick Alp{\'e}rovitch and Will, \{Robert G\} and St{\'e}phane Ha{\"i}k",

year = "2009",

doi = "10.1002/ana.21583",

language = "English",

volume = "65",

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T1 - Variant Creutzfeldt-Jakob disease in France and the United Kingdom

T2 - Evidence for the same agent strain

AU - Brandel, Jean-Philippe

AU - Heath, Craig A

AU - Head, Mark W

AU - Levavasseur, Etienne

AU - Knight, Richard

AU - Laplanche, Jean-Louis

AU - Langeveld, Jan Pm

AU - Ironside, James W

AU - Hauw, Jean-Jacques

AU - Mackenzie, Jan

AU - Alpérovitch, Annick

AU - Will, Robert G

AU - Haïk, Stéphane

PY - 2009

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AB - Variant Creutzfeldt-Jakob disease (vCJD) was first reported in the United Kingdom in 1996. Since then, the majority of cases have been observed in the United Kingdom where there was a major epidemic of bovine spongiform encephalopathy. France was the second country affected. To address the hypothesis of the involvement of a common strain of agent, we have compared clinical, neuropathological, and biochemical data on vCJD patients from both countries.

U2 - 10.1002/ana.21583

DO - 10.1002/ana.21583

M3 - Article

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SN - 1531-8249

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SP - 249

EP - 256

JO - Annals of Neurology

JF - Annals of Neurology

IS - 3

ER -

Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain

Abstract

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