Variant Creutzfeldt-Jakob disease: Neuropsychological profile in an extended series of cases

Kari Hawkins, Gurjit Chohan, Christopher Kipps, Robert Will, Narinder Kapur

Research output: Contribution to journalArticlepeer-review

Abstract

Neuropsychological data on an extended series of cases of variant Creutzfeldt-Jakob Disease (vCJD) are presented, complementing earlier findings from smaller sample studies of this condition. Distinct neuropsychological features in this extended series included relatively preserved verbal knowledge, immediate verbal memory span, and elementary Visual processing. This sparing contrasted with ubiquitous impairment in every vCJD patient on timed tests of verbal fluency and digit-symbol substitution. There were also high rates of impairment on tests of memory, and of visuoperceptual and visuospatial reasoning. our findings lend Support to the view that distinctive neuropsychological features may be one of the diagnostic markers of the condition. (JINS. 2009, 15, 807-810.)

Original languageEnglish
Pages (from-to)807-810
Number of pages4
JournalJournal of the International Neuropsychological Society
Volume15
Issue number5
DOIs
Publication statusPublished - Sep 2009

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