Variation in chemotherapy prescribing rates and mortality in early breast cancer over two decades: A national data linkage study

Ewan Gray; Jonine D Figueroa; Olga Oikonomidou; Iain Macpherson; Gordon Urquhart; David A Cameron; Peter S Hall

doi:10.1016/j.esmoop.2021.100331

Variation in chemotherapy prescribing rates and mortality in early breast cancer over two decades: A national data linkage study

Ewan Gray, Jonine D Figueroa, Olga Oikonomidou, Iain Macpherson, Gordon Urquhart, David A Cameron, Peter S Hall^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Highlights
• A cohort study including the Scottish population of surgically treated early breast cancer patients from 2001 to 2018.

• With adequate case mix adjustment, regional variation in adjuvant chemotherapy use was small, but with notable outliers.

• Over time there was a trend towards greater convergence in practice towards risk-stratified treatment recommendations.

Original language	English
Journal	ESMO Open
Early online date	2 Dec 2021
DOIs	https://doi.org/10.1016/j.esmoop.2021.100331
Publication status	E-pub ahead of print - 2 Dec 2021

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title = "Variation in chemotherapy prescribing rates and mortality in early breast cancer over two decades: A national data linkage study",

abstract = "Highlights• A cohort study including the Scottish population of surgically treated early breast cancer patients from 2001 to 2018.• With adequate case mix adjustment, regional variation in adjuvant chemotherapy use was small, but with notable outliers.• Over time there was a trend towards greater convergence in practice towards risk-stratified treatment recommendations.",

author = "Ewan Gray and Figueroa, {Jonine D} and Olga Oikonomidou and Iain Macpherson and Gordon Urquhart and Cameron, {David A} and Hall, {Peter S}",

year = "2021",

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T1 - Variation in chemotherapy prescribing rates and mortality in early breast cancer over two decades: A national data linkage study

AU - Gray, Ewan

AU - Figueroa, Jonine D

AU - Oikonomidou, Olga

AU - Macpherson, Iain

AU - Urquhart, Gordon

AU - Cameron, David A

AU - Hall, Peter S

PY - 2021/12/2

Y1 - 2021/12/2

N2 - Highlights• A cohort study including the Scottish population of surgically treated early breast cancer patients from 2001 to 2018.• With adequate case mix adjustment, regional variation in adjuvant chemotherapy use was small, but with notable outliers.• Over time there was a trend towards greater convergence in practice towards risk-stratified treatment recommendations.

AB - Highlights• A cohort study including the Scottish population of surgically treated early breast cancer patients from 2001 to 2018.• With adequate case mix adjustment, regional variation in adjuvant chemotherapy use was small, but with notable outliers.• Over time there was a trend towards greater convergence in practice towards risk-stratified treatment recommendations.

U2 - 10.1016/j.esmoop.2021.100331

DO - 10.1016/j.esmoop.2021.100331

M3 - Article

SN - 2059-7029

JO - ESMO Open

JF - ESMO Open

ER -

Variation in chemotherapy prescribing rates and mortality in early breast cancer over two decades: A national data linkage study

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