Virus-host interactomes and global models of virus-infected cells

Caroline C. Friedel, Juergen Haas

Research output: Contribution to journalLiterature reviewpeer-review


Novel high-throughput technologies such as yeast two-hybrid and RNA interference (RNAi) screens provide the tools to study interactions between viral proteins and the host on a genomic scale. In this review, we provide an overview of studies in which these technologies were applied and cif computational approaches for the analysis of the identified viral interactors in the context of the host cell. The results of these studies illustrate the advantages cif integrative systems biology approaches in the investigation of viral pathogens.

Original languageEnglish
Pages (from-to)501-508
Number of pages8
JournalTrends in Microbiology
Issue number10
Publication statusPublished - Oct 2011

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