Virus immunocapture provides evidence of CD8 lymphocyte-derived HIV-1 in vivo

Gareth J Hughes, Samantha Willey, Alexandra Cochrane, Clifford Leen, Jeanne E Bell, Peter Simmonds

Research output: Contribution to journalArticlepeer-review

Abstract

To demonstrate that HIV-1 immunocapture with an antibody against CD8 specifically captures virions derived from infected CD8 T cells, and to determine the proportion of HIV-1 derived from CD8 lymphocytes in plasma samples from HIV-infected individuals.
Original languageEnglish
Pages (from-to)1507-13
Number of pages7
JournalAIDS
Volume21
Issue number12
DOIs
Publication statusPublished - 31 Jul 2007

Keywords

  • CD4 Lymphocyte Count
  • CD8-Positive T-Lymphocytes
  • Cells, Cultured
  • Disease Progression
  • HIV Infections
  • HIV-1
  • Humans
  • Proviruses
  • Reverse Transcriptase Polymerase Chain Reaction
  • T-Lymphocyte Subsets
  • Viral Load
  • Virion

Fingerprint

Dive into the research topics of 'Virus immunocapture provides evidence of CD8 lymphocyte-derived HIV-1 in vivo'. Together they form a unique fingerprint.

Cite this