Vitamin D: testing and supplementation in adults

Clare MacRae, Ben Pearson-Stuttard, Stuart H Ralston

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Vitamin D is essential for the maintenance of musculoskeletal health through the regulation of calcium and phosphate homeostasis. Severe prolonged deficiency of vitamin D can lead to rickets in children and osteomalacia in adults. Both conditions are now rare in the UK, except in high-risk groups such as those with malabsorption and reduced exposure to sunlight. A much more common situation is ‘biochemical’ vitamin D deficiency, where circulating 25(OH)D concentrations fall below pre-defined thresholds in the absence of osteomalacia or rickets, making vitamin D deficiency and insufficiency very common in the UK particularly during the winter months and early spring. Biochemical vitamin D deficiency has been associated with various non-skeletal disorders, but it seems likely that the low vitamin D levels in these situations are the result of the underlying condition, rather than the cause.
Original languageEnglish
JournalInnovAiT: Education and inspiration for general practice
Early online date10 Sept 2020
Publication statusE-pub ahead of print - 10 Sept 2020

Keywords / Materials (for Non-textual outputs)

  • Vitamin D Deficiency
  • Vitamin D supplementation


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