Vulnerable newborn types: Analysis of population-based registries for 165 million births in 23 countries, 2000 to 2021

The National Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group, Lorena Suárez-Idueta, Judith Yargawa, Hannah Blencowe, Ellen Bradley, Yemisrach B. Okwaraji, Veronica Pingray, Luz Gibbons, Adrienne Gordon, Kara Warrilow, Enny S. Paixão, Ila Rocha Falcão, Sarka Lisonkova, Qi Wen, Francisco Mardones, Raúl Caulier-Cisterna, Petr Velebil, Jitka Jírová, Erzsebet Horváth-Puhó, Henrik Toft SørensenLuule Sakkeus, Lili Abuladze, Mika Gissler, Mohammad Heidarzadeh, Maziar Moradi-Lakeh, Khalid A. Yunis, Ayah Al Bizri, Shamala D. Karalasingam, Ravichandran Jeganathan, Arturo Barranco, Lisa Broeders, Aimée E. van Dijk, Luis Huicho, Hugo Guillermo Quezada-Pinedo, Kim Nail Cajachagua-Torres, Fawziya Alyafei, Mai AlQubaisi, Geum Joon Cho, Ho Yeon Kim, Neda Razaz, Jonas Söderling, Lucy K. Smith, Jennifer Kurinczuk, Estelle Lowry, Neil Rowland, Rachael Wood, Kirsten Monteath, Isabel Pereyra, Gabriella Pravia, Eric O. Ohuma, Joy E. Lawn

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Objective To examine prevalence of novel newborn types among 165 million livebirths in 23 countries from 2000 to 2021.
Design Population-based, multi-country analysis.
Setting National data systems in 23 middle and high-income countries.
Population Liveborn infants
Methods Country teams with high-quality data were invited to be part of the Vulnerable Newborn Measurement Collaboration. We classified livebirths by six newborn types based on gestational age information (preterm, PT, 90th centile) for gestational age, according to INTERGROWTH-21st standards. We considered small newborn types of any combination of preterm or SGA and Term+LGA was considered large. Time trends were analysed using three-year moving averages for small and large types.
Main Outcome Measures Prevalence of six newborn types.
Results We analysed 165,017,419 livebirths and the median prevalence of small types was 11.7% (highest in Malaysia (26%) and Qatar (15.7%)). Overall, 18.1% of newborns were large (T+LGA), and was highest in Estonia 28.8% and Denmark 25.9%. Time trends of small and large infants were relatively stable in most countries.
Conclusions The distribution of newborn types varies across the 23 middle and high-income countries. Small newborn types were highest in West-Asian countries and large types in Europe. To better understand the global patterns of these novel newborn types, more information is needed especially from low- and middle- income countries.
Original languageEnglish
JournalBJOG: An International Journal of Obstetrics and Gynaecology
Early online date8 May 2023
Publication statusE-pub ahead of print - 8 May 2023


Dive into the research topics of 'Vulnerable newborn types: Analysis of population-based registries for 165 million births in 23 countries, 2000 to 2021'. Together they form a unique fingerprint.

Cite this