Activities per year
Abstract / Description of output
Use of wearable devices that monitor physical activity is projected to increase more than fivefold per half-decade1. We investigated how device-based physical activity energy expenditure (PAEE) and different intensity profiles were associated with all-cause mortality. We used a network harmonization approach to map dominant-wrist acceleration to PAEE in 96,476 UK Biobank participants (mean age 62 years, 56% female). We also calculated the fraction of PAEE accumulated from moderate-to-vigorous-intensity physical activity (MVPA). Over the median 3.1-year follow-up period (302,526 person-years), 732 deaths were recorded. Higher PAEE was associated with a lower hazard of all-cause mortality for a constant fraction of MVPA (for example, 21% (95% confidence interval 4–35%) lower hazard for 20 versus 15 kJ kg−1 d−1 PAEE with 10% from MVPA). Similarly, a higher MVPA fraction was associated with a lower hazard when PAEE remained constant (for example, 30% (8–47%) lower hazard when 20% versus 10% of a fixed 15 kJ kg−1 d−1 PAEE volume was from MVPA). Our results show that higher volumes of PAEE are associated with reduced mortality rates, and achieving the same volume through higher-intensity activity is associated with greater reductions than through lower-intensity activity. The linkage of device-measured activity to energy expenditure creates a framework for using wearables for personalized prevention.
Original language | English |
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Pages (from-to) | 1385–1391 |
Journal | Nature Medicine |
Volume | 26 |
Early online date | 17 Aug 2020 |
DOIs | |
Publication status | Published - 1 Sept 2020 |
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Physical activity in the UK Biobank
Tessa Strain (Invited speaker)
18 Dec 2019Activity: Academic talk or presentation types › Invited talk
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Associations of wrist-worn accelerometry with all-cause mortality in 94,863 adults: The UK Biobank Study
Tessa Strain (Speaker)
5 Jun 2019Activity: Academic talk or presentation types › Oral presentation