Wearable-device-measured physical activity and future health risk

Tessa Strain, Katrien Wijndaele, Paddy C. Dempsey, Stephen J. Sharp, Matthew Pearce, Justin Jeon, Tim Lindsay, Nick Wareham, Søren Brage

Research output: Contribution to journalLetterpeer-review

Abstract / Description of output

Use of wearable devices that monitor physical activity is projected to increase more than fivefold per half-decade1. We investigated how device-based physical activity energy expenditure (PAEE) and different intensity profiles were associated with all-cause mortality. We used a network harmonization approach to map dominant-wrist acceleration to PAEE in 96,476 UK Biobank participants (mean age 62 years, 56% female). We also calculated the fraction of PAEE accumulated from moderate-to-vigorous-intensity physical activity (MVPA). Over the median 3.1-year follow-up period (302,526 person-years), 732 deaths were recorded. Higher PAEE was associated with a lower hazard of all-cause mortality for a constant fraction of MVPA (for example, 21% (95% confidence interval 4–35%) lower hazard for 20 versus 15 kJ kg−1 d−1 PAEE with 10% from MVPA). Similarly, a higher MVPA fraction was associated with a lower hazard when PAEE remained constant (for example, 30% (8–47%) lower hazard when 20% versus 10% of a fixed 15 kJ kg−1 d−1 PAEE volume was from MVPA). Our results show that higher volumes of PAEE are associated with reduced mortality rates, and achieving the same volume through higher-intensity activity is associated with greater reductions than through lower-intensity activity. The linkage of device-measured activity to energy expenditure creates a framework for using wearables for personalized prevention.
Original languageEnglish
Pages (from-to)1385–1391
JournalNature Medicine
Volume26
Early online date17 Aug 2020
DOIs
Publication statusPublished - 1 Sept 2020

Fingerprint

Dive into the research topics of 'Wearable-device-measured physical activity and future health risk'. Together they form a unique fingerprint.

Cite this