What are SARS-CoV-2 genomes from the WHO Africa region member states telling us?

Research output: Contribution to journalComment/debatepeer-review

Abstract / Description of output

Summary box
To date, 23 countries from the WHO Africa region have deposited a total of 3995 SARS-CoV-2 sequences to publicly available databases, with the majority of the genomes being from South Africa (56%).

Eight-four different lineages have been identified from these countries with 86% genomes belonging to the B.1 sublineage and its descendants.

There have been multiple separate introductions of SARS-CoV-2 infections into Africa, with approximately 43% of these coming from Europe.

95% of African SARS-CoV-2 genomes have the D614G mutation in spike protein thought to be associated with higher infectivity but lower disease severity.
Original languageEnglish
Article numbere004408
JournalBMJ Global Health
Volume6
Issue number1
Early online date8 Jan 2021
DOIs
Publication statusPublished - 8 Jan 2021

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