Whole blood manganese concentrations in dogs with primary hepatitis

Scott Kilpatrick, A Jacinto, R D Foale, S W Tappin, C Burton, P E Frowde, C M Elwood, R Powell, A Duncan, R J Mellanby, Adam Gow

Research output: Contribution to journalArticlepeer-review

Abstract

Increased whole blood manganese concentrations have been reported in humans with primary liver disease. Due to the neurotoxic effects of manganese, altered manganese homeostasis has been linked to the development of hepatic encephalopathy. Whole blood manganese concentrations are increased in cases of canine congenital portosystemic shunts, but it remains unclear whether dogs with primary hepatopathies also have altered manganese homeostasis.
Original languageEnglish
JournalJournal of Small Animal Practice
VolumeE-pub 5 March
Early online date5 Mar 2014
DOIs
Publication statusPublished - 5 Mar 2014

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