Wnt signaling and injury repair

Jemima L Whyte; Andrew A Smith; Jill A Helms

doi:10.1101/cshperspect.a008078

Wnt signaling and injury repair

Jemima L Whyte, Andrew A Smith, Jill A Helms

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Wnt signaling is activated by wounding and participates in every subsequent stage of the healing process from the control of inflammation and programmed cell death, to the mobilization of stem cell reservoirs within the wound site. In this review we summarize recent data elucidating the roles that the Wnt pathway plays in the injury repair process. These data provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating tissue regeneration.

Original language	English
Pages (from-to)	a008078
Journal	Cold Spring Harbor perspectives in biology
Volume	4
Issue number	8
DOIs	https://doi.org/10.1101/cshperspect.a008078
Publication status	Published - Aug 2012

Keywords / Materials (for Non-textual outputs)

Animals
Apoptosis
Humans
Inflammation
Models, Biological
Regeneration
Species Specificity
Wnt Signaling Pathway
Wound Healing

Access to Document

10.1101/cshperspect.a008078

Postdoctoral Research Fellow: Development of a Wnt based therapeutic for skin wound healing
Whyte, J. & Helms, J. A.
1/09/10 → 1/09/12
Project: Project from a former institution

Cite this

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title = "Wnt signaling and injury repair",

abstract = "Wnt signaling is activated by wounding and participates in every subsequent stage of the healing process from the control of inflammation and programmed cell death, to the mobilization of stem cell reservoirs within the wound site. In this review we summarize recent data elucidating the roles that the Wnt pathway plays in the injury repair process. These data provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating tissue regeneration.",

keywords = "Animals, Apoptosis, Humans, Inflammation, Models, Biological, Regeneration, Species Specificity, Wnt Signaling Pathway, Wound Healing",

author = "Whyte, {Jemima L} and Smith, {Andrew A} and Helms, {Jill A}",

year = "2012",

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AU - Smith, Andrew A

AU - Helms, Jill A

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AB - Wnt signaling is activated by wounding and participates in every subsequent stage of the healing process from the control of inflammation and programmed cell death, to the mobilization of stem cell reservoirs within the wound site. In this review we summarize recent data elucidating the roles that the Wnt pathway plays in the injury repair process. These data provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating tissue regeneration.

KW - Animals

KW - Apoptosis

KW - Humans

KW - Inflammation

KW - Models, Biological

KW - Regeneration

KW - Species Specificity

KW - Wnt Signaling Pathway

KW - Wound Healing

U2 - 10.1101/cshperspect.a008078

DO - 10.1101/cshperspect.a008078

M3 - Article

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SN - 1943-0264

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SP - a008078

JO - Cold Spring Harbor perspectives in biology

JF - Cold Spring Harbor perspectives in biology

IS - 8

ER -

Wnt signaling and injury repair

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

Access to Document

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Projects

Postdoctoral Research Fellow: Development of a Wnt based therapeutic for skin wound healing

Cite this