Wnt signaling and injury repair

Jemima L Whyte, Andrew A Smith, Jill A Helms

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Wnt signaling is activated by wounding and participates in every subsequent stage of the healing process from the control of inflammation and programmed cell death, to the mobilization of stem cell reservoirs within the wound site. In this review we summarize recent data elucidating the roles that the Wnt pathway plays in the injury repair process. These data provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating tissue regeneration.
Original languageEnglish
Pages (from-to)a008078
JournalCold Spring Harbor perspectives in biology
Issue number8
Publication statusPublished - Aug 2012

Keywords / Materials (for Non-textual outputs)

  • Animals
  • Apoptosis
  • Humans
  • Inflammation
  • Models, Biological
  • Regeneration
  • Species Specificity
  • Wnt Signaling Pathway
  • Wound Healing


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