Wnt signaling and injury repair

Jemima L Whyte, Andrew A Smith, Jill A Helms

Research output: Contribution to journalArticlepeer-review

Abstract

Wnt signaling is activated by wounding and participates in every subsequent stage of the healing process from the control of inflammation and programmed cell death, to the mobilization of stem cell reservoirs within the wound site. In this review we summarize recent data elucidating the roles that the Wnt pathway plays in the injury repair process. These data provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating tissue regeneration.
Original languageEnglish
Pages (from-to)a008078
JournalCold Spring Harbor perspectives in biology
Volume4
Issue number8
DOIs
Publication statusPublished - Aug 2012

Keywords

  • Animals
  • Apoptosis
  • Humans
  • Inflammation
  • Models, Biological
  • Regeneration
  • Species Specificity
  • Wnt Signaling Pathway
  • Wound Healing

Fingerprint

Dive into the research topics of 'Wnt signaling and injury repair'. Together they form a unique fingerprint.

Cite this