Wnt signalling in pituitary development and tumorigenesis.

Thomas Chambers; Adam Giles; Georg Brabant; Julian Davis

doi:10.1530/erc-13-0005

Wnt signalling in pituitary development and tumorigenesis.

Thomas Chambers, Adam Giles, Georg Brabant, Julian Davis

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Wnt signalling is activated in both pituitary organogenesis and its mature function. Wnt ligands and Wnt signalling pathways are critical for the regulation of the formation of the pituitary. In the mature pituitary, Wnt signalling pathways control cell activity and may stimulate cell proliferation in both physiological and pathological processes. This review compares Wnt signalling pathways active in the developing and mature pituitary and explores how this gives us further insight into the development of pituitary adenomas.

Original language	English
Journal	Endocrine-Related Cancer
DOIs	https://doi.org/10.1530/erc-13-0005
Publication status	Published - 20 May 2013

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title = "Wnt signalling in pituitary development and tumorigenesis.",

abstract = "Wnt signalling is activated in both pituitary organogenesis and its mature function. Wnt ligands and Wnt signalling pathways are critical for the regulation of the formation of the pituitary. In the mature pituitary, Wnt signalling pathways control cell activity and may stimulate cell proliferation in both physiological and pathological processes. This review compares Wnt signalling pathways active in the developing and mature pituitary and explores how this gives us further insight into the development of pituitary adenomas.",

author = "Thomas Chambers and Adam Giles and Georg Brabant and Julian Davis",

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AU - Giles, Adam

AU - Brabant, Georg

AU - Davis, Julian

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AB - Wnt signalling is activated in both pituitary organogenesis and its mature function. Wnt ligands and Wnt signalling pathways are critical for the regulation of the formation of the pituitary. In the mature pituitary, Wnt signalling pathways control cell activity and may stimulate cell proliferation in both physiological and pathological processes. This review compares Wnt signalling pathways active in the developing and mature pituitary and explores how this gives us further insight into the development of pituitary adenomas.

UR - https://doi.org/10.1530/ERC-13-0005

U2 - 10.1530/erc-13-0005

DO - 10.1530/erc-13-0005

M3 - Article

C2 - 23689382

SN - 1351-0088

JO - Endocrine-Related Cancer

JF - Endocrine-Related Cancer

ER -

Wnt signalling in pituitary development and tumorigenesis.

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