Xenogenic extracellular matrices as potential biomaterials for interposition grafting in urological surgery

N F Davis, B B McGuire, A Callanan, H D Flood, T M McGloughlin

Research output: Contribution to journalArticlepeer-review

Abstract

The field of tissue engineering focuses on developing strategies for reconstructing injured, diseased, and congenitally absent tissues and organs. During the last decade urologists have benefited from remodeling and regenerative properties of bioscaffolds derived from xenogenic extracellular matrices. We comprehensively reviewed the current literature on structural and functional characteristics of xenogenic extracellular matrix grafting since it was first described in urological surgery. We also reviewed the clinical limitations, and assessed the potential for safe and effective urological application of extracellular matrix grafting in place of autogenous tissue.
Original languageEnglish
Pages (from-to)2246-53
Number of pages8
JournalThe Journal of urology
Volume184
Issue number6
DOIs
Publication statusPublished - 2010

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