Edinburgh Research Explorer

Gene expression in the cardiovascular system of the domestic sheep (Ovis aries)

Dataset

Related Edinburgh Organisations

PublisherEdinburgh DataShare
Date made available27 Apr 2020
Geographical coverageUK,UNITED KINGDOM

Abstract

This dataset includes gene expression estimates, from RNA-Seq, for seven cardiovascular and one skeletal muscle tissue from the sheep gene expression atlas dataset (https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006997). The raw RNA-seq data are deposited in the European Nucleotide Archive (ENA) under study accession number PRJEB19199 (http://www.ebi.ac.uk/ena/data/view/PRJEB19199). For each tissue a set of expression estimates (averaged across biological replicates from where possible n=6 adult sheep), as transcripts per million (TPM), were obtained using the transcript quantification tool Kallisto v0.43.0. It was necessary to normalise these estimates to account for the two different library types (ribo-depleted total RNA (left ventricle) and poly-A selected mRNA (all other tissues).

Data Citation

Tsang, Hiu-Gwen; Clark, Emily L; Markby, Greg A; Bush, Stephen J; Hume, David A; Corcoran, Brendan M; MacRae, Vicky E; Summers, Kim M. (2020). Gene expression in the cardiovascular system of the domestic sheep (Ovis aries), [dataset]. University of Edinburgh. The Roslin Institute.. https://doi.org/10.7488/ds/2808.

ID: 146339342