Edinburgh Research Explorer

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging

Dataset

  • Xiuqing Guo (Creator)
  • Jeeson Jung (Creator)
  • Silva Kasela (Creator)
  • Seyma Katrinli (Creator)
  • Pei-Lun Kuo (Creator)
  • Pamela Matias-Garcia (Creator)
  • Pashupati Mishra (Creator)
  • Marianne Nygaard (Creator)
  • Teemu Palviainen (Creator)
  • Amit Patki (Creator)
  • Laura Raffield (Creator)
  • Scott Ratliff (Creator)
  • Tom Richardson (Creator)
  • Oliver Robinson (Creator)
  • Mette Sorensen (Creator)
  • Dianjianyi Sun (Creator)
  • Pei-Chien Tsai (Creator)
  • Matthijs van der Zee (Creator)
  • Xiaochuan Wang (Creator)
  • Yunzhang Wang (Creator)
  • Rui Xia (Creator)
  • Zongli Xu (Creator)
  • Jie Yao (Creator)
  • Wei Zhao (Creator)
  • Ian Deary (Creator)
  • Caroline Relton (Creator)
  • Steve Horvath (Creator)
  • Riccardo Marioni (Creator)
  • Ayoung Jeong (Creator)
  • Daniel Mccartney (Creator)
  • Josine Min (Creator)
  • Rebecca Richmond (Creator)
  • Ake Lu (Creator)
  • Maria Sobczyk (Creator)
  • Gail Davies (Creator)
  • Linda Broer (Creator)

Related Edinburgh Organisations

PublisherEdinburgh DataShare
Date made available1 Jul 2020
Geographical coverageUK,UNITED KINGDOM

Abstract

These files contain summary statistics for meta-analysis GWAS of six traits in European, African and Trans-Ancestry. There are 18 files in total - 6 for each ancestry by 3 for each trait. The traits are DNA methylation proxies for granulocyte proportions (gran) and plasminogen activator inhibitor-1 (PAI1), and four epigenetic age acceleration measures of: PhenoAge, GrimAge, HannumAge, and Intrinsic Epigenetic Age Acceleration (IEAA).

Data Citation

McCartney, Daniel; Min, Josine; Richmond, Rebecca; Lu, Ake; Sobczyk, Maria; Davies, Gail; Broer, Linda; Guo, Xiuqing; Jeong, Ayoung; Jung, Jeeson; Kasela, Silva; Katrinli, Seyma; Kuo, Pei-Lun; Matias-Garcia, Pamela; Mishra, Pashupati; Nygaard, Marianne; Palviainen, Teemu; Patki, Amit; Raffield, Laura; Ratliff, Scott; Richardson, Tom; Robinson, Oliver; Sorensen, Mette; Sun, Dianjianyi; Tsai, Pei-Chien; van der Zee, Matthijs; Wang, Xiaochuan; Wang, Yunzhang; Xia, Rui; Xu, Zongli; Yao, Jie; Zhao, Wei; Deary, Ian; Relton, Caroline; Horvath, Steve; Marioni, Riccardo. (2020). Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging, [dataset]. University of Edinburgh. Centre for Cognitive Ageing and Cognitive Epidemiology.

ID: 150330062