Edinburgh Research Explorer

Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis

Dataset

Related Edinburgh Organisations

PublisherEdinburgh DataShare
Date made available31 Mar 2020
Geographical coverageScotland,UK,UNITED KINGDOM

Abstract

Data from Wigmore et al "Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP". The Pharmacogenomics Journal 20, 329–341 (2020) DOI:10.1038/s41397-019-0067-3

This dataset consists of two sets of GWAS summary statistics:

- case-control analysis of treatment resistance phenotype in the Generation Scotland and GENDEP samples (inverse variance weighted meta-analysis). Cases = 358, Controls = 3855.
- quantitative stages of resistance phenotype in Generation Scotland. N = 3452.

Data Citation

Wigmore, Ella; Hafferty, Jonathan; Hall, Lynsey; Howard, David; Clarke, Toni-Kim; Fabbri, Chiara; Lewis, Cathryn; Uher, Rudolf; Navrady, Lauren; Adams, Mark; Zeng, Yanni; Campbell, Archie; Gibson, Jude; Thomson, Pippa; Hayward, Caroline; Smith, Blair; Hocking, Lynne; Padmanabhan, Sandosh; Deary, Ian; Porteous, David; Mors, Ole; Mattheisen, Manuel; Nicodemus, Kristin; McIntosh, Andrew. (2020). Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis, [dataset]. University of Edinurgh. Centre for Clinical Brain Sciences. Department of Psychiatry. https://doi.org/10.7488/ds/2791.

ID: 142707621