Edinburgh Research Explorer

Mitotic chromosomes fold by condensin-dependent helical winding of chromatin loop arrays

Dataset

  • Johan H. Gibcus (Creator)
  • Anton Goloborodko (Creator)
  • Kumiko Samejima (Creator)
  • Itaru Samejima (Creator)
  • Natalia Naumova (Creator)
  • Masato T Kanemaki (Creator)
  • Linfeng Xie (Creator)
  • James R. Paulson (Creator)
  • Bill Earnshaw (Creator)
  • Leonid A Mirny (Creator)
  • Job Dekker (Creator)

Related Edinburgh Organisations

PublisherNational Center for Biotechnology Information (Gene Expression Omnibus)
Date made available18 Jan 2018

Description

Chromosome organization investigation through Hi-C

Abstract

Mitotic chromosome morphogenesis occurs through condensin-mediated disassembly of the interphase conformation and formation of extended prophase loop arrays that then shorten by condensin-dependent helical winding.

Data Citation

Gibcus JH, Samejima K, Goloborodko A, Samejima I et al. A pathway for mitotic chromosome formation. Science 2018 Feb 9;359(6376). PMID: 29348367

ID: 54950106