Edinburgh Research Explorer

The third International Stroke Trial (IST-3)


Related Edinburgh Organisations

PublisherEdinburgh DataShare
Temporal coverage1 Jan 2000 - 31 Dec 2015
Date made available1 Jan 2021
Geographical coverageUnited Kingdom, Australia, Austria, Belgium, Canada, Italy, Norway, Poland, Portugal, Sweden, Switzerland


The IST-3 trial is a large-scale randomised controlled trial of intravenous thrombolytic therapy with the drug Alteplase. The dataset includes a number of files describing the IST-3 dataset. The documentation files may be freely downloaded. The patient-level data are under embargo until the 25th of January 2021.

Data Citation

Sandercock, P; Wardlaw, J; Lindley, R; Cohen, G; Whiteley, W. (2016). The third International Stroke Trial (IST-3), 2000-2015 [dataset]. University of Edinburgh & Edinburgh Clinical Trials Unit. http://dx.doi.org/10.7488/ds/1350

ID: 24312449