Edinburgh Research Explorer

Centre for Genomic and Experimental Medicine

Organisational unit: Research Centre

  1. 2019
  2. Alirocumab therapy in individuals with type 2 diabetes mellitus and atherosclerotic cardiovascular disease: analysis of the ODYSSEY DM-DYSLIPIDEMIA and DM-INSULIN studies

    Ray, K. K., Del Prato, S., Müller-Wieland, D., Cariou, B., Colhoun, H. M., Tinahones, F. J., Domenger, C., Letierce, A., Mandel, J., Samuel, R., Bujas-Bobanovic, M. & Leiter, L. A., 9 Nov 2019, In : Cardiovascular diabetology. 18, 1, p. 149

    Research output: Contribution to journalArticle

  3. Relationship between alirocumab, PCSK9, and LDL-C levels in four phase 3 ODYSSEY trials using 75 and 150 mg doses

    Robinson, J. G., Farnier, M., Kastelein, J. J. P., Roth, E. M., Taskinen, M-R., Colhoun, H. M., Brunet, A., DiCioccio, A. T., Lecorps, G., Pordy, R., Baccara-Dinet, M. T. & Cannon, C. P., 12 Nov 2019, In : Journal of clinical lipidology. 13, 6, p. 979-988.e10

    Research output: Contribution to journalArticle

  4. A meta-analysis of genome-wide association studies of epigenetic age acceleration

    Gibson, J., Russ, T., Clarke, T-K., Howard, D., Hillary, R., Evans, K., Walker, R., Bermingham, M., Morris, S., Campbell, A., Hayward, C., Murray, A., Porteous, D., Horvath, S., Lu, A. T., McIntosh, A., Whalley, H. & Marioni, R., 18 Nov 2019, In : PLoS Genetics. 15, 11, 53 p., e1008104.

    Research output: Contribution to journalArticle

  5. A major role for common genetic variation in anxiety disorders

    Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., Mcintosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, Nordentoft, M., Werge, T., Nicodemus, K. K., Mattheisen, M., Breen, G. & Eley, T. C., 20 Nov 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  6. Anti-MDA5 juvenile idiopathic inflammatory myopathy: a specific subgroup defined by differentially enhanced interferon-α signalling

    Melki, I., Devilliers, H., Gitiaux, C., Bondet, V., Duffy, D., Charuel, J-L., Miyara, M., Bokov, P., Kheniche, A., Kwon, T., Authier, F-J., Allenbach, Y., Belot, A., Bodemer, C., Bourrat, E., Dumaine, C., Fabien, N., Faye, A., Frémond, M-L., Hadchouel, A. & 14 others, Kitabayashi, N., Lepelley, A., Martin-Niclos, M. J., Mudumba, S., Musset, L., Quartier, P., Rice, G. I., Seabra, L., Uettwiller, F., Uggenti, C., Viel, S., Rodero, M. P., Crow, Y. & Bader-Meunier, B., 22 Nov 2019, In : Rheumatology.

    Research output: Contribution to journalArticle

  7. Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments

    Habota, T., Sandu, A., Waiter, G. D., Mcneil, C. J., Steele, J. D., Macfarlane, J. A., Whalley, H. C., Valentine, R., Younie, D., Crouch, N., Hawkins, E. L., Hirose, Y., Romaniuk, L., Milburn, K., Buchan, G., Coupar, T., Stirling, M., Jagpal, B., Maclennan, B., Priba, L. & 20 others, Harris, M. A., Hafferty, J. D., Adams, M. J., Campbell, A. I., Macintyre, D. J., Pattie, A., Murphy, L., Reynolds, R. M., Elliot, R., Penton-voak, I. S., Munafò, M. R., Evans, K. L., Seckl, J. R., Wardlaw, J. M., Lawrie, S. M., Haley, C. S., Porteous, D. J., Deary, I. J., Murray, A. D. & Mcintosh, A. M., 25 Nov 2019, In : Wellcome Open Research . 4, p. 185

    Research output: Contribution to journalArticle

  8. DNA methylation Aging Clocks: Challenges & Recommendations

    Bell, C. G., Lowe, R., Adams, P. D., Baccarelli, A. A., Beck, S., Bell, J. T., Christensen, B. C., Gladyshev, V. N., Heijmans, B. T., Horvath, S., Ideker, T., Issa, J-P. J., Kelsey, K. T., Marioni, R., Reik, W., Relton, C. L., Schalkwyk, L. C., Teschendorff, A. E., Wagner, W., Zhang, K. & 1 others, Rakyan, V. K., 25 Nov 2019, In : Genome Biology.

    Research output: Contribution to journalArticle

  9. Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

    Clarke, T., Adams, M. J., Howard, D. M., Xia, C., Davies, G., Hayward, C., Campbell, A., Padmanabhan, S., Smith, B. H., Murray, A., Porteous, D., Deary, I. J. & Mcintosh, A. M., 25 Nov 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle