Edinburgh Research Explorer

Centre for Genomic and Experimental Medicine

Organisational unit: Research Centre

  1. 2019
  2. Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice

    Marino, S., de Ridder, D., Bishop, R. T., Renema, N., Ponzetti, M., Sophocleous, A., Capulli, M., Aljeffery, A., Carrasco, G., Gens, M. D., Khogeer, A., Ralston, S. H., Gertsch, J., Lamoureux, F., Heymann, D., Rucci, N. & Idris, A. I., Jun 2019, In : EBioMedicine. 44, p. 452-466 15 p.

    Research output: Contribution to journalArticle

  3. Germline selection shapes human mitochondrial DNA diversity

    NIHR BioResource-Rare Dis & 100000 Genomes Project-Rare Dis, 24 May 2019, In : Science. 364, 6442, p. 749-+ 59 p.

    Research output: Contribution to journalArticle

  4. Long term effects of teriparatide followed by antiresorptive therapy on clinical outcomes in patients with severe spinal osteoporosis

    Oswald, A., Berg, K., Ralston, S. & Riches, P., 21 May 2019, In : Calcified Tissue International.

    Research output: Contribution to journalArticle

  5. Glycaemic control trends in people with Type 1 diabetes in Scotland 2004-2016

    Mair, C., Wulaningsih, W., Jeyam, A., McGurnaghan, S., Blackbourn, L., Kennon, B., Leese, G. P., Lindsay, R., McCrimmon, R. J., McKnight, J., Petrie, J. R., Sattar, N., Wild, S., Conway, N., Craigie, I., Robertson, K., Bath, L., McKeigue, P. & Colhoun, H., 18 May 2019, In : Diabetologia.

    Research output: Contribution to journalReview article

  6. Association analyses identify 31 new risk loci for colorectal cancer susceptibility

    Law, P. J., Timofeeva, M., Fernandez-Rozadilla, C., Broderick, P., Studd, J. B., Fernandez-Tajes, J., Farrington, S., Svinti MacLeod, V., Palles, C., Orlando, G., Sud, A., Amy, H., Penegar, S., Theodoratou, E., Vaughan-Shaw, P., Campbell, H., Zgaga, L., Hayward, C., Campbell, A., Harris, S. & 78 others, Deary, I., Starr, J., Laura, G., Pinna, M., Briggs, S., Martin, L., Jaeger, E., Sharma-Oates, A., East, J., Leedham, S., Arnold, R., Johnstone, E., Wang, H., Kerr, D., Kerr, R., Maughan, T., Kaplan, R., Al-Tassan, N. A., Palin, K., Hanninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Eriksson, J., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S., Palotie, A., Renkonen-Sinisalo, L., Lepisto, A., Böhm, J., Mecklin, J-P., Buchanan, D., Win, A. K., Hopper, J. L., Jenkins, M. C., Lindor, N. M., Newcomb, P. A., Gallinger, S., Duggan, D., Casey, G., Hoffman, P., Nöthen, M. M., Jöckel, K-H., Easton, D. F., Pharoah, P. D. P., Peto, J., Canzian, F., Swerdlow, A. J., Eeles, R. A., Kote-Jarai, Z., Muir, K. R., Pashayan, N., Harkin, A., Allan, K., McQueen, J., Paul, J., Iveson, T., Saunders, M. N. K., Butterbach, K., Chang-Claude, J., Hoffmeister, M., Brenner, H., Kirac, I., Matošević, P., Hofer, P., Brezina, S., Gsur, A., Cheadle, J., Aaltonen, L., Tomlinson, I., Houlston, R. S. & Dunlop, M., 14 May 2019, In : Nature Communications.

    Research output: Contribution to journalArticle

  7. Epigenome-wide association study of lung function level and its change

    Imboden, M., Wielscher, M., Rezwan, F. I., Amaral, A. F. S., Schaffner, E., Jeong, A., Beckmeyer-Borowko, A., Harris, S., Starr, J., Deary, I., Flexeder, C., Waldenberger, M., Peters, A., Schulz, H., Chen, S., Shadia Khan, S., Karmaus, W. J. J., Jiang, Y., Erhart, G., Kronenberg, F. & 19 others, Arathimos, R., Sharp, G. C., Henderson, A. J., Fu, Y., Piirilä, P., Pietiläinen, K. H., Ollikainen, M., Johansson, A., Gyllensten, U., de Vries, M., van der Plaat, D. A., de Jong, K., Boezen, H. M., Hall, I. P., Tobin, M. D., Jarvelin, M-R., Holloway, J. W., Jarvis, D. L. & Probst-Hensch, N. M., 9 May 2019, In : European Respiratory Journal. 53, 5

    Research output: Contribution to journalArticle

  8. Point-of-care uric acid testing is useful in routine clinical care of gout

    Riches, P. L., Sing, K. & Berg, K., 9 May 2019, In : Arthritis research & therapy. 21, 1, p. 117

    Research output: Contribution to journalArticle

  9. Biallelic variants in DNA2 cause microcephalic primordial dwarfism

    Tarnauskaitė, Ž., Bicknell, L. S., Marsh, J. A., Murray, J. E., Parry, D. A., Logan, C. V., Bober, M. B., Silva, D. C., Duker, A. L., Sillence, D., Wise, C., Jackson, A. P., Murina, O. & Reijns, M. A. M., 2 May 2019, In : Human Mutation.

    Research output: Contribution to journalArticle

  10. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S-C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L-P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 1 May 2019, In : Nature Communications. 10, 1, p. 2068

    Research output: Contribution to journalArticle

  11. Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy

    Findlay, E. G., Currie, A. J., Zhang, A., Ovciarikova, J., Young, L., Stevens, H., Mchugh, B. J., Canel, M., Gray, M., Milling, S. W. F., Campbell, J. D. M., Savill, J., Serrels, A. & Davidson, D. J., 1 May 2019, In : OncoImmunology. p. 1-17

    Research output: Contribution to journalArticle

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