Edinburgh Research Explorer

Centre for Neuroregeneration

Organisational unit: Research Centre

  1. 2020
  2. Methylation deficiency disrupts biological rhythms from bacteria to humans

    Fustin, J-M., Ye, S., Rakers, C., Kaneko, K., Fukumoto, K., Yamano, M., Versteven, M., Grunewald, E., Cargill, S., Tamai, T. K., Xu, Y., Jabbur, M. L., Kojima, R., Lamberti, M. L., Yoshioka Kobayashi, K., Whitmore, D., Tammam, S., Howell, P. L., Kageyama, R., Matsuo, T. & 6 others, Stanewsky, R., Golombek, D. A., Johnson, C. H., Kakeya, H., Van Ooijen, G. & Okamura, H., 6 May 2020, In: Communications biology. 3, 1, 14 p., 211.

    Research output: Contribution to journalArticlepeer-review

  3. 2018
  4. DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

    Malavasi, E. L. V., Economides, K. D., Grünewald, E., Makedonopoulou, P., Gautier, P., Mackie, S., Murphy, L. C., Murdoch, H., Crummie, D., Ogawa, F., McCartney, D. L., O'Sullivan, S. T., Burr, K., Torrance, H. S., Phillips, J., Bonneau, M., Anderson, S. M., Perry, P., Pearson, M., Constantinides, C. & 16 others, Davidson-Smith, H., Kabiri, M., Duff, B., Johnstone, M., Polites, H. G., Lawrie, S. M., Blackwood, D. H., Semple, C. A., Evans, K. L., Didier, M., Chandran, S., McIntosh, A. M., Price, D. J., Houslay, M. D., Porteous, D. J. & Millar, J. K., 6 Sep 2018, In: Translational Psychiatry. 8, 1, p. 184

    Research output: Contribution to journalArticlepeer-review

  5. Homozygous mutation in the Neurofascin gene affecting the glial isoform of Neurofascin causes severe neurodevelopment disorder with hypotonia, amimia and areflexia

    Smigiel, R., Sherman, D. L., Rydzanicz, M., Walczak, A., Mikolajkow, D., Krolak-Olejnik, B., Kosinska, J., Gasperowicz, P., Biernacka, A., Stawinski, P., Marciniak, M., Andrzejewski, W., Boczar, M., Krajewski, P., Sasiadek, M. M., Brophy, P. J. & Ploski, R., 15 Aug 2018, In: Human Molecular Genetics.

    Research output: Contribution to journalArticlepeer-review

  6. A murine model of Charcot-Marie-Tooth disease 4F reveals a role for the C-terminus of periaxin in the formation and stabilization of Cajal bands

    Sherman, D. L. & Brophy, P. J., 1 Mar 2018, In: Wellcome Open Research . 3, p. 20

    Research output: Contribution to journalArticlepeer-review

  7. Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

    Manso Sanz, Y., Holland, P., Kitamura, A., Szymkowiak, S., Duncombe, J., Hennessy, E., Searcy, J., Marangoni, M., Randall, A. D., Brown, J., McColl, B. & Horsburgh, K., Jan 2018, In: Glia. 66, 1, p. 34-46

    Research output: Contribution to journalArticlepeer-review

  8. The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion

    Hase, Y., Craggs, L., Hase, M., Stevenson, W., Slade, J., Chen, A., Liang, D., Ennaceur, A., Oakley, A., Ihara, M., Horsburgh, K. & Kalaria, R. N., Jan 2018, In: Journal of Cerebral Blood Flow and Metabolism. 38, 1, p. 271678X17694904

    Research output: Contribution to journalArticlepeer-review

  9. 2017
  10. Corrigendum: Mechanisms underlying the activity-dependent regulation of locomotor network performance by the Na pump

    Zhang, H-Y., Picton, L., Li, W-C. & Sillar, K. T., 22 Dec 2017, In: Scientific Reports. 7, p. 46909

    Research output: Contribution to journalComment/debate

  11. Ca 2+ activity signatures of myelin sheath formation and growth in vivo

    Baraban, M., Koudelka, S. & Lyons, D. A., 11 Dec 2017, In: Nature Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  12. Ki-67 and the Chromosome Periphery Compartment in Mitosis

    Booth, D. G. & Earnshaw, W. C., 1 Dec 2017, In: Trends In Cell Biology. 27, 12, p. 906-916 11 p.

    Research output: Contribution to journalReview articlepeer-review

  13. The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments

    Percie du Sert, N., Alfieri, A., Allan, S. M., Carswell, H. V. O., Deuchar, G. A., Farr, T. D., Flecknell, P., Gallagher, L., Gibson, C., Haley, M. J., MacLeod, M., McColl, B., McCabe, C., Morancho, A., Moon, L., O'Neill, M., Perez de Puig, I., Planas, A., Ragan, I., Rosell, A. & 10 others, Roy, L., Ryder, K., Simats, A., Sena, E., Sutherland, B., Tricklebank, M., Trueman, R., Whitfield, L., Wong, R. & Macrae, M., Nov 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 11, p. 3488-3517 30 p., 271678X17709185.

    Research output: Contribution to journalArticlepeer-review

  14. Gold-Triggered Uncaging Chemistry in Living Systems

    Perez-Lopez, A. M., Rubio Ruiz, B., Sebastian, V., Hamilton, L., Adam, C., Bray, T. L., Irusta, S., Brennan, P. M., Lloyd-Jones, G. C., Sieger, D., Santamaria, J. & Unciti-Broceta, A., 2 Oct 2017, In: Angewandte Chemie. 129, 41, p. 12722-12726 5 p.

    Research output: Contribution to journalArticlepeer-review

  15. Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis

    Duncombe, J., Lennen, R. J., Jansen, M. A., Marshall, I., Wardlaw, J. M. & Horsburgh, K., Oct 2017, In: Neuropathology and Applied Neurobiology. 43, 6

    Research output: Contribution to journalArticlepeer-review

  16. A synthetic cell permeable antioxidant protects neurons against acute oxidative stress

    Drummond, N., Davies, N. O., Lovett, J., Miller, M., Cook, G., Becker, T., Becker, C. G., McPhail, D. & Kunath, T., 19 Sep 2017, In: Scientific Reports. 7, 1, 11857.

    Research output: Contribution to journalArticlepeer-review

  17. Drug discovery for remyelination and treatment of MS

    Cole, K. L. H., Early, J. J. & Lyons, D. A., 16 Aug 2017, In: Glia.

    Research output: Contribution to journalReview articlepeer-review

  18. Therapeutic strategies for spinal muscular atrophy: SMN and beyond

    Bowerman, M., Becker, C. G., Yáñez-Muñoz, R. J., Ning, K., Wood, M. J., Gillingwater, T. & Talbot, K., 2 Aug 2017, In: Disease Models & Mechanisms. 10, 8

    Research output: Contribution to journalArticlepeer-review

  19. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish

    Wehner, D., Tsarouchas, T. M., Michael, A., Haase, C., Weidinger, G., Reimer, M. M., Becker, T. & Becker, C. G., 25 Jul 2017, In: Nature Communications. 8, 17 p., 126.

    Research output: Contribution to journalArticlepeer-review

  20. Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and hemorrhages in Tg-SwDI mice

    Salvadores, N., Searcy, J. L., Holland, P. R. & Horsburgh, K., 24 Jul 2017, In: Clinical science.

    Research output: Contribution to journalArticlepeer-review

  21. Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

    Kitamura, A., Manso Sanz, Y., Duncombe, J., Searcy, J., Koudelka, J., Binnie, M., Webster, S., Lennen, R. J., Jansen, M., Ihara, M., Kalaria, R. N. & Horsburgh, K., 27 Jun 2017, In: Scientific Reports.

    Research output: Contribution to journalArticlepeer-review

  22. Dimethyl fumarate improves white matter function following severe hypoperfusion: involvement of microglia/macrophages and inflammatory mediators

    Fowler, J., Mcqueen, J., Holland, P., Manso Sanz, Y., Marangoni, M., Scott, F., Chisholm, E., Scannevin, R. H., Hardingham, G. & Horsburgh, K., 13 Jun 2017, In: Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalArticlepeer-review

  23. Regeneration of myelin sheaths of normal length and thickness in the zebrafish CNS correlates with growth of axons in caliber

    Karttunen, M., Czopka, T., Goedhart, M., Early, J. & Lyons, D., 25 May 2017, In: PLoS ONE.

    Research output: Contribution to journalArticlepeer-review

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