Edinburgh Research Explorer

Hepatology/Gastroenterology

Organisational unit: Research Group

  1. 2021
  2. Thrombin is An Effective and Safe Therapy in the 
Management of Bleeding Gastric Varices. A Real-World 
Experience

    Gillespie, S-L., McAvoy, N. C., Yung, D., Robertson, A., Plevris, J. & Hayes, P. C., Feb 2021.

    Research output: Contribution to conferencePaperpeer-review

  3. 2020
  4. aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis

    Fan, R., Papatheodoridis, G., Sun, J., Innes, H., Toyoda, H., Xie, Q., Mo, S., Sypsa, V., Guha, I. N., Kumada, T., Niu, J., Dalekos, G., Yasuda, S., Barnes, E., Lian, J., Suri, V., Idilman, R., Barclay, S. T., Dou, X., Berg, T. & 22 others, Hayes, P. C., Flaherty, J. F., Zhou, Y., Zhang, Z., Buti, M., Hutchinson, S. J., Guo, Y., Calleja, J. L., Lin, L., Zhao, L., Chen, Y., Janssen, H. L. A., Zhu, C., Shi, L., Tang, X., Gaggar, A., Wei, L., Jia, J., Irving, W. L., Johnson, P. J., Lampertico, P. & Hou, J., 1 Dec 2020, In: Journal of Hepatology. 73, 6, p. 1368-1378

    Research output: Contribution to journalArticlepeer-review

  5. Development of a cost effective automated platform to produce human liver spheroids for basic and applied research

    Lucendo-Villarin, B., Meseguer Ripolles, J., Drew, J., Fisher, L., Ma, E., Flint, O., Simpson, K. J., Machesky, L. M., Mountford, J. C. & Hay, D. C., 28 Oct 2020, In: Biofabrication. 13, 1, 015009.

    Research output: Contribution to journalArticlepeer-review

  6. The eye as a non-invasive window to the microcirculation in liver cirrhosis: a prospective pilot study

    Gifford, F., Moroni, F., Farrah, T., Hetherington, K., MacGillivray, T., Hayes, P. C., Dhaun, N. & Fallowfield, J. A., 17 Oct 2020, In: Journal of Clinical Medicine.

    Research output: Contribution to journalArticlepeer-review

  7. Genome-wide association study for alcohol-related cirrhosis Identifies risk loci in MARC1 and HNRNPUL1

    Innes, H. A., Buch, S., Hutchinson, S. J., Neil Guha, I., Morling, J. R., Barnes, E., Irving, W., Forrest, E., Pedergnana, V., Goldberg, D. J., Aspinall, E. J., Barclay, S., Hayes, P. C., Dillon, J., Dieter Nischalke, H., Lutz, P., Spengler, U., Fischer, J., Berg, T., Brosch, M. & 11 others, Eyer, F., Data, C., Mueller, S., Peccerella, T., Deltenre, P., Merot, A., Soyka, M., McQuillin, A., Morgan, M. Y., Hampe, J. & Stickel, F., 5 Oct 2020.

    Research output: Contribution to conferencePaperpeer-review

  8. Guidelines on the management of ascites in cirrhosis

    Aithal, G. P., Palaniyappan, N., China, L., Harmala, S., Macken, L., Ryan, J., A Wilkes, E., Moore, K., Leithead, J. A., Hayes, P. C., O'Brien, A. J. & Verma, S., 4 Sep 2020.

    Research output: Contribution to conferencePaperpeer-review

  9. Ribavirin for Hepatitis E Virus Infection After Organ Transplantation: A Large European Retrospective Multicenter Study

    Simpson, K. J. & Hepatitis E Virus Ribavirin Study Group , 1 Sep 2020, In: Clinical Infectious Diseases. 71, 5, p. 1204-1211 8 p.

    Research output: Contribution to journalArticlepeer-review

  10. Expression Profiles of Exosomal MicroRNAs from HEV- and HCV-Infected Blood Donors and Patients: A Pilot Study

    McGowan, K., Simpson, K. J. & Petrik, J., 30 Jul 2020, In: Viruses. 12, 8

    Research output: Contribution to journalArticlepeer-review

  11. Non-invasive risk scores do not reliably identify future cirrhosis or hepatocellular carcinoma in Type 2 diabetes: The Edinburgh Type 2 Diabetes Study

    Grecian, S., McLachlan, S., Fallowfield, J. A., Kearns, P., Hayes, P. C., Guha, I. N., Morling, J., Glancy, S., Williamson, R. M., Reynolds, R. M., Frier, B., Zammitt, N. N., Price, J. F. & Strachan, M., 7 Jul 2020, In: Liver International.

    Research output: Contribution to journalArticlepeer-review

  12. Randomised clinical trial: standard of care versus early-transjugular intrahepatic porto-systemic shunt (TIPSS) in patients with cirrhosis and oesophageal variceal bleeding

    Dunne, P., Sinha, R., Stanley, A. J., Lachlan, N., Ireland, H., Shams, A., Kasthuri, R., Forrest, E. H. & Hayes, P., Jul 2020, In: Alimentary Pharmacology and Therapeutics. 52, 1, p. 98

    Research output: Contribution to journalArticlepeer-review

  13. A Volatomic Analysis Identifies Compounds for Stratification of Non- Alcoholic Fatty Liver Disease: A Pilot Study

    Sinha, R., Lockman, K. A., Homer, N., Bower, E., Brinkman, P., Knobel, H., Fallowfield, J., Jaap, A., Hayes, P. & Plevris, J., 15 Jun 2020, In: JHEP Reports.

    Research output: Contribution to journalArticlepeer-review

  14. Volatomic analysis identifies compounds that can stratify non-alcoholic fatty liver disease

    Sinha, R., Lockman, K. A., Homer, N., Bower, E., Brinkman, P., Knobel, H. H., Fallowfield, J., Jaap, A. J., Hayes, P. & Plevris, J. N., 15 Jun 2020, In: JHEP Reports.

    Research output: Contribution to journalArticlepeer-review

  15. When Is a Critically Ill Cirrhotic Patient Too Sick to Transplant? Development of Consensus Criteria by a Multidisciplinary Panel of 35 International Experts

    Weiss, E., Saner, F., Asrani, S. K., Biancofiore, G., Blasi, A., Lerut, J., Durand, F., Fernandez, J., Findlay, J. Y., Fondevila, C., Francoz, C., Gustot, T., Jaber, S., Karvellas, C., Kronish, K., Laleman, W., Laterre, P. F., Levesque, E., Mandell, S. M., McPhail, M. & 16 others, Muiesan, P., Olson, J. C., Olthoff, K., Pinna, A. D., Reiberger, T., Reyntjens, K., Saliba, F., Scatton, O., Simpson, K. J., Soubrane, O., Subramanian, R. M., Tacke, F., Tomescu, D., Xia, V., Wagener, G. & Paugam-Burtz, C., 15 Jun 2020, In: Transplantation.

    Research output: Contribution to journalArticlepeer-review

  16. SARS-CoV-2 and the liver

    Morgan, K., Samuel, K., Vandeputte, M., Hayes, P. & Plevris, J., 30 May 2020, In: Pathogens. 9, 6, 430.

    Research output: Contribution to journalReview articlepeer-review

  17. The reported ‘clear cut time association between interferon-free treatment and HCC’ is anything but clear cut

    Innes, H. A., Mcdonald, S. A., Barclay, S. T., Irving, W. L., Hayes, P. C. & Hutchinson, S. J., 1 May 2020, In: Journal of Hepatology. 72, 5, p. 1034-1035

    Research output: Contribution to journalLetter

  18. Mortality and morbidity of locally acquired hepatitis E in the national Scottish cohort: a multicentre retrospective study

    Wallace, S. J., Swann, R., Donnelly, M., Kemp, L., Guaci, J., Murray, A., Spoor, J., Lin, N., Miller, M., Dalton, H. R., Hussaini, S. H., Gunson, R., Simpson, K., Stanley, A. & Fraser, A., May 2020, In: Alimentary Pharmacology and Therapeutics. 51, 10, p. 974-986 13 p.

    Research output: Contribution to journalArticlepeer-review

  19. Oxygen plasma substrate and specific nanopattern promote early differentiation of HepaRG progenitors

    Morgan, K., Bryans, A., Brzeszczyński, F., Samuel, K., Treskes, P., Brzeszczynska, J., Morley, S. D., Hayes, P. C., Gadegaard, N., Nelson, L. J. & Plevris, J. N., 15 Apr 2020, In: Tissue Engineering, Part A.

    Research output: Contribution to journalArticlepeer-review

  20. Population impact of direct-acting antiviral treatment on new presentations of hepatitis C-related decompensated cirrhosis: a national record-linkage study

    Hutchinson, S. J., Valerio, H., McDonald, S. A., Yeung, A., Pollock, K., Smith, S., Barclay, S., Dillon, J. F., Fox, R., Bramley, P., Fraser, A., Kennedy, N., Gunson, R. N., Templeton, K., Innes, H., McLeod, A., Weir, A., Hayes, P. C. & Goldberg, D., 26 Mar 2020, In: Gut.

    Research output: Contribution to journalArticlepeer-review

  21. Validation of Reference Genes for Gene Expression Studies by RT-qPCR in HepaRG Cells during Toxicity Testing and Disease Modelling

    Brzeszczyńska, J., Brzeszczyński, F., Samuel, K., Morgan, K., Morley, S. D., Plevris, J. N. & Hayes, P. C., 21 Mar 2020, In: Cells. 9, 3

    Research output: Contribution to journalArticlepeer-review

  22. A Phase 2 Randomised Controlled Trial of Serelaxin to Lower Portal Pressure in Cirrhosis (STOPP)

    Gifford, F., Dunne, P., Weir, G., Graham, C., Tuck, S., Hayes, P. & Fallowfield, J., 12 Mar 2020, In: Trials.

    Research output: Contribution to journalArticlepeer-review

  23. Real-world impact following initiation of interferon-free hepatitis C regimens on liver-related outcomes and all-cause mortality among patients with compensated cirrhosis

    McDonald, S. A., Pollock, K. G. J., Barclay, S. T., Goldberg, D. J., Bathgate, A. J., Bramley, P., Dillon, J., Fraser, A., Innes, H., Kennedy, N., Morris, J., Went, A., Hayes, P. & Hutchison, S., Mar 2020, In: Journal of Viral Hepatitis.

    Research output: Contribution to journalArticlepeer-review

  24. Transjugular intrahepatic portosystemic stent-shunt in the management of portal hypertension

    Tripathi, D., Stanley, A. J., Hayes, P. C., Travis, S., Armstrong, M. J., Tsochatzis, E. A., Rowe, I. A., Roslund, N., Ireland, H., Lomax, M., Leithead, J. A., Mehrzad, H., Aspinall, R. J., McDonagh, J. & Patch, D., 29 Feb 2020

    Research output: Other contribution

  25. Role of impedance based cellular assays in Hepatology research

    Morgan, K., Gamal, W., Samuel, K., Morley, S., Hayes, P., Bagnaninchi, P. & Plevris, J., 15 Jan 2020, Encyclopedia. MDPI AG

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  26. Transjugular intrahepatic portosystemic stent-shut in the management of portal hypertension

    Tripathi, D., Stanley, A. J., Hayes, P., Travis, S. P. L., Armstrong, M., Tsochatzis, E., Rowe, I., Roslund, N., Ireland, H., Lomax, M., Leithead, J., Mehrzad, H., Aspinall, R., McDonagh, J. & Patch, D., Jan 2020.

    Research output: Contribution to conferencePaperpeer-review

  27. 2019
  28. Application of Impedance-Based Techniques in Hepatology Research

    Morgan, K., Gamal, W., Samuel, K., Morley, S. D., Hayes, P. C., Bagnaninchi, P. & Plevris, J. N., 24 Dec 2019, In: Journal of Clinical Medicine. 9, 1, p. 50

    Research output: Contribution to journalArticlepeer-review

  29. Coffee consumption and kidney function: A Mendelian randomisation study

    Kennedy, O. J., Pirastu, N., Poole, R., Fallowfield, J., Hayes, P., Grzeszkowiak, E. J., Taal, M. W., Wilson, J., Parkes, J. & Roderick, P., 11 Dec 2019, In: American Journal of Kidney Diseases.

    Research output: Contribution to journalArticlepeer-review

  30. Using problem-based learning (PBL) to engage undergraduate medical students in endocrinology at Edinburgh Medical School

    Pender, F. T. & Morley, S. D., 11 Nov 2019, In: Endocrine Abstracts. 65, 1 p., P248.

    Research output: Contribution to journalMeeting abstractpeer-review

  31. Safety profile of autologous macrophage therapy for liver cirrhosis

    Moroni, F., Dwyer, B., Graham, C., Pass, C., Bailey, L., Ritchie, L., Mitchell, D., Glover, A., Laurie, A., Doig, S., Hargreaves, E., Fraser, A. R., Turner, M. L., Campbell, J. D. M., McGowan, N. W. A., Barry, J., Moore, J. K., Hayes, P. C., Leeming, D. J., Nielsen, M. J. & 3 others, Musa, K., Fallowfield, J. A. & Forbes, S. J., Oct 2019, In: Nature Medicine. 25, 10, p. 1560–1565 6 p.

    Research output: Contribution to journalArticlepeer-review

  32. THE EYE AS A NON-INVASIVE WINDOW TO THE MICROCIRCULATION IN CIRRHOSIS: A PROSPECTIVE COHORT STUDY

    Gifford, F. J., Moroni, F., Farrah, T., Hetherington, K., MacGillivray, T. J., Hayes, P., Dhaun, N. & Fallowfield, J. A., Oct 2019, In: Hepatology. 70, p. 193A-193A 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  33. Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis.

    Forrest, E. H., Storey, N., Sinha, R., Atkinson, S. R., Vergis, N., Richardson, P., Masson, S., Ryder, S., Thursz, M. R., Allison, M., Fraser, A., Austin, A., McCune, A., Dhanda, A., Katarey, D., Potts, J., Verma, S., Parker, R. & Hayes, P., Aug 2019, In: Alimentary Pharmacology and Therapeutics. 50, 4

    Research output: Contribution to journalArticlepeer-review

  34. Uptake of endoscopic screening for gastroesophageal varices and factors associated with variceal bleeding in patients with chronic hepatitis C infection and compensated cirrhosis, 2005-2016: a national database linkage study.

    McDonald, S. A., Barclay, S. T., Hutchinson, S. J., Stanley, A. J., Fraser, A., Dillon, J. F., Innes, H. A., Peters, E., Kennedy, N., Bathgate, A. J., Bramley, P., Morris, J., Goldberg, D. J. & Hayes, P., Aug 2019, In: Alimentary Pharmacology and Therapeutics. 50, 4

    Research output: Contribution to journalArticlepeer-review

  35. Gut-liver crosstalk and gut homeostasis in paracetamol toxicity: In Vitro Study Using Impedence-Based Assay

    Morgan, K., Samuel, K., Gamal, W., Morley, S., Hayes, P., Bagnaninchi, P. & Plevris, J., Jun 2019, In: Gut. 68, Suppl 2: A1–A269, p. A124 1 p., PTU-026.

    Research output: Contribution to journalMeeting abstractpeer-review

  36. Experiences of diagnosis, stigma, culpability and disclosure in male patients with hepatitis C virus: An interpretative phenomenological analysis.

    Krzeczkowska, A., Flowers, P., Chouliara, Z., Hayes, P. & Dickson, A., 13 May 2019, In: Health.

    Research output: Contribution to journalArticlepeer-review

  37. Study protocol for a randomised controlled trial of carvedilol versus variceal band ligation in primary prevention of variceal bleeding in liver cirrhosis

    CALIBRE trial collaborative group, 25 Apr 2019, In: BMJ open gastroenterology.

    Research output: Contribution to journalArticlepeer-review

  38. Chlorpromazine toxicity is associated with disruption of cell membrane integrity and initiation of a pro-inflammatory response in the HepaRG hepatic cell line

    Morgan, F., Martucci, N., Kozlowska, A., Gamal, W., Brzeszczynki, F., Treskes, P., Samuel, K., Hayes, P., Nelson, L., Bagnaninchi, P., Brzeszczynska, J. & Plevris, J., Mar 2019, In: Biomedicine and Pharmacotherapy. 111, p. 1408-1416 9 p.

    Research output: Contribution to journalArticlepeer-review

  39. Loss of integrin αvβ8 in murine hepatocytes accelerates liver regeneration

    Greenhalgh, S., Matchett, K., Taylor, R., Huang, K., Li, J. T., Saeteurn, K., Donnelly, M. C., Simpson, E. E. M., Pollack, J. L., Atakilit, A., Simpson, K., Maher, J. J., Iredale, J., Sheppard, D. & Henderson, N., 1 Feb 2019, In: American Journal of Pathology. 189, 2, p. 258-271

    Research output: Contribution to journalArticlepeer-review

  40. 2018
  41. QRT-PCR analysis of the effect of in utero exposure to sewage sludge on steroidogenic gene expression in ovine fetal adrenal gland

    Cooper, E. A., Reddy, S., Allenson, A. Z., Cooper, D. P., Fowler, P. A., T Rae, M. T. & Morley, S. D., Nov 2018, In: Endocrine Abstracts. 59, p. P038 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  42. Letter to the Editor: Human based systems: Mechanistic NASH modelling just around the corner?'

    Morgan, F., Fassoula, V., Samuel, K., Morley, S., Hayes, P. & Plevris, J., 10 Oct 2018, In: Pharmacological Research. 137, p. 208-281 2 p., https://doi.org/10.1016/j.phrs.2018.09.028.

    Research output: Contribution to journalLetterpeer-review

  43. Earlier use of capsule endoscopy in inpatients with melena or severe iron deficiency anemia reduces need for colonoscopy and shortens hospital stay

    Yung, D. E., Koulaouzidis, A., Douglas, S. & Plevris, J. N., Sep 2018, In: Endoscopy International Open. 6, 9, p. E1075-E1084

    Research output: Contribution to journalArticlepeer-review

  44. 'It's been a long haul, a big haul, but we've made it': hepatitis C virus treatment in post-transplant patients with virus recurrence: An interpretative phenomenological analysis.

    Krzeczkowska, A., Flowers, P., Chouliara, Z., Hayes, P. & Dickson, A., 6 Aug 2018, In: Health Psychology Open.

    Research output: Contribution to journalArticlepeer-review

  45. Index serum hyaluronic acid independently and accurately predicts mortality in patients with liver disease

    Plevris, N., Sinha, R., Hay, A. W., McDonald, N., Plevris, J. N. & Hayes, P. C., Aug 2018, In: Alimentary Pharmacology and Therapeutics.

    Research output: Contribution to journalArticlepeer-review

  46. Computer simulation of neutral drift among limbal epithelial stem cells of mosaic mice

    West, J. D., Mort, R. L., Hill, R. E., Morley, S. D. & Collinson, J. M., 1 Jul 2018, In: Stem Cell Research. 30, p. 1-11

    Research output: Contribution to journalArticlepeer-review

  47. A study of breath metabolome in Non-alcoholic fatty liver disease

    Sinha, R., Lockman, K. A., Homer, N., Bower, E., Brinkman, P., Knobel, H., Chamuleau, R., Jaap, A., Hayes, P. & Plevris, J., Apr 2018, In: Journal of Hepatology. 68, p. S557-S558 2 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  48. Electronic-nose breath print distinguishes non-alcoholic fatty liver disease from healthy lean control: A pilot study

    Sinha, R., Gallagher, I., Lockman, K. A., Chamuleau, R., Jaap, A., Hayes, P. & Plevris, J., Apr 2018, In: Journal of Hepatology. 68, p. S556-S557 2 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  49. Challenges in the diagnosis of leptospirosis outwith endemic settings: a Scottish single centre experience

    Russell, C. D., Jones, M. E., O'Shea, D. T., Simpson, K. J., Mitchell, A. & Laurenson, I. F., 31 Mar 2018, In: Journal of the Royal College of Physicians of Edinburgh. 48, 1, p. 9-15 7 p.

    Research output: Contribution to journalArticlepeer-review

  50. Impact of previous hepatitis B infection on the clinical outcomes from chronic hepatitis C? A population-level analysis

    Wang, H., Swann, R., Thomas, E., Innes, H. A., Valerio, H., Hayes, P. C., Allen, S., Barclay, S. T., Wilks, D., Fox, R., Bhattacharyya, D., Kennedy, N., Morris, J., Fraser, A., Stanley, A. J., Gunson, R., Mclntyre, P. G., Hunt, A., Hutchinson, S. J., Mills, P. R. & 1 others, Dillon, J. F., 25 Mar 2018, In: Journal of Viral Hepatitis.

    Research output: Contribution to journalArticlepeer-review

  51. Hepatitis E virus (HEV) in Scotland: evidence of recent increase in viral circulation in humans

    Thom, K., Gilhooly, P., McGowan, K., Malloy, K., Jarvis, L. M., Crossan, C., Scobie, L., Blatchford, O., Smith-Palmer, A., Donnelly, M. C., Davidson, J. S., Johannessen, I., Simpson, K. J., Dalton, H. R. & Petrik, J., 22 Mar 2018, In: Eurosurveillance. 23, 12

    Research output: Contribution to journalArticlepeer-review

  52. Palliative care for people with advanced liver disease: a feasibility trial of a supportive care liver nurse specialist

    Kimbell, B., Murray, S., Byrne, H., Baird, A., Hayes, P. C., MacGilchrist, A., Finucane, A., Brookes-Young, P., O'Carroll, R., Weir, C. J., Kendall, M. & Boyd, K., 8 Mar 2018, In: Palliative Medicine. p. 1-11

    Research output: Contribution to journalArticlepeer-review

  53. Endoscopic ultrasound assessment of gastrointestinal polypoid lesions of indeterminate morphology in patients with portal hypertension

    Sigounas, D. E., Shams, A., Hayes, P. C. & Plevris, J. N., Mar 2018, In: Endoscopy International Open. 6, 3, p. E292-E299

    Research output: Contribution to journalArticlepeer-review

  54. Nondestructive Optical Toxicity Assays of 3D Liver Spheroids with Optical Coherence Tomography

    Martucci, N. J., Morgan, K., Anderson, G. W., Hayes, P. C., Plevris, J. N., Nelson, L. J. & Bagnaninchi, P. O., Mar 2018, In: Advanced Biosystems. 2, 3, p. 1700212

    Research output: Contribution to journalArticlepeer-review

  55. Primary prophylaxis of variceal bleeding.

    Robertson, M. & Hayes, P., 2 Feb 2018, In: Hepatology International.

    Research output: Contribution to journalEditorialpeer-review

  56. 2017
  57. Inpatient hospital burden of hepatitis C-diagnosed patients with decompensated cirrhosis

    McDonald, S. A., Innes, H. A., Aspinall, E. J., Hayes, P. C., Alavi, M., Valerio, H., Goldberg, D. J. & Hutchinson, S. J., 30 Dec 2017, In: Liver International.

    Research output: Contribution to journalArticlepeer-review

  58. The management of bleeding from anorectal varices

    Robertson, M., Thompson, A. I. & Hayes, P., Dec 2017, In: Current Hepatology Reports. 16, 4

    Research output: Contribution to journalArticlepeer-review

  59. Trends in hepatocellular carcinoma incidence and survival among people with hepatitis C: an international comparison

    Alavi, M., Janjua, N. Z., Chong, M., Grebely, J., Aspinall, E. J., Innes, H., Valerio, H., Hajarizadeh, B., Hayes, P. C., Krajden, M., Amin, J., Law, M. G., George, J., Goldberg, D. J., Hutchinson, S. J. & Dore, G. J., 30 Nov 2017, In: Journal of Viral Hepatitis.

    Research output: Contribution to journalArticlepeer-review

  60. Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes

    Poole, R., Kennedy, O. J., Roderick, P., Fallowfield, J. A., Hayes, P. C. & Parkes, J., 22 Nov 2017, In: British Medical Journal (BMJ). 359, 8131, 18 p., j5024.

    Research output: Contribution to journalArticlepeer-review

  61. The risk of hepatocellular carcinoma in cirrhotic patients with hepatitis C and sustained viral response: role of the treatment regimen

    Innes, H. A., Barclay, S. T., Hayes, P., Fraser, A. G., Dillon, J. F., Stanley, A. J., Bathgate, A., McDonald, S. A., Goldberg, D. J., Valerio, H., Fox, R., Kennedy, N., Bramley, P. & Hutchinson, S. J., 16 Nov 2017, In: Hepatology.

    Research output: Contribution to journalArticlepeer-review

  62. Capsule endoscopy in young patients with iron deficiency anaemia and negative bidirectional gastrointestinal endoscopy

    Yung, D. E., Rondonotti, E., Giannakou, A., Avni, T., Rosa, B., Toth, E., Lucendo, A. J., Sidhu, R., Beaumont, H., Ellul, P., Negreanu, L., Jiménez-Garcia, V. A., McNamara, D., Kopylov, U., Elli, L., Triantafyllou, K., Shibli, F., Riccioni, M. E., Bruno, M., Dray, X. & 23 others, Plevris, J. N., Koulaouzidis, A., Argüelles-Arias, F., Becq, A., Branchi, F., Tejero-Bustos, M. Á., Cotter, J., Eliakim, R., Ferretti, F., Gralnek, I. M., Herrerias-Gutierrez, J. M., Hussey, M., Jacobs, M., Johansson, G. W., McAlindon, M., Montiero, S., Nemeth, A., Pennazio, M., Rattehalli, D., Stemate, A., Tortora, A., Tziatzios, G. & And the Capsule Endoscopy in Young Patients with IDA research group, Nov 2017, In: United European Gastroenterology Journal. 5, 7, p. 974-981 8 p.

    Research output: Contribution to journalArticlepeer-review

  63. SIRT1 CONTROLS ACETAMINOPHEN HEPATOTOXICITY BY MODULATING INFLAMMATION AND OXIDATIVE STRESS

    Rada, P., Pardo, V., Mobasher, M., Garcia, I., Ruiz, L., Gonzalez Rodriguez, A., Sánchez Ramos, C., Muntané, J., Alemany, S., James, L. P., Simpson, K. J., Monsalve, M., Valdecantos, M. P. & Valverde, A., 31 Oct 2017, In: Antioxidants and Redox Signaling.

    Research output: Contribution to journalArticlepeer-review

  64. The contribution of alcohol-use disorder to decompensated cirrhosis among people with hepatitis C: an international study

    Alavi, M., Janjua, N. Z., Chong, M., Grebely, J., Aspinall, E. J., Innes, H., Valerio, H. M., Hajarizadeh, B., Hayes, P. C., Krajden, M., Amin, J., Law, M. G., George, J., Goldberg, D. J., Hutchinson, S. J. & Dore, G. J., 26 Oct 2017, In: Journal of Hepatology.

    Research output: Contribution to journalArticlepeer-review

  65. Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury

    Sydor, S., Manka, P., Best, J., Jafoui, S., Sowa, J-P., Zoubek, M. E., Hernandez-Gea, V., Cubero, F. J., Kälsch, J., Vetter, D., Fiel, M. I., Hoshida, Y., Bian, C. B., Nelson, L. J., Moshage, H., Faber, K. N., Paul, A., Baba, H. A., Gerken, G., Friedman, S. L. & 2 others, Canbay, A. & Bechmann, L. P., 14 Aug 2017, In: Scientific Reports. 7, 1, p. 8119

    Research output: Contribution to journalArticlepeer-review

  66. Systematic review and meta-analysis: is bowel preparation still necessary in small bowel capsule endoscopy?

    Yung, D. E., Rondonotti, E., Sykes, C., Pennazio, M., Plevris, J. N. & Koulaouzidis, A., 1 Aug 2017, In: Expert Review of Gastroenterology and Hepatology. p. 1-15 15 p.

    Research output: Contribution to journalArticlepeer-review

  67. Review article: hepatitis E-a concise review of virology, epidemiology, clinical presentation and therapy

    Donnelly, M. C., Scobie, L., Crossan, C. L., Dalton, H., Hayes, P. C. & Simpson, K. J., Jul 2017, In: Alimentary Pharmacology and Therapeutics. 46, 2, p. 126-141 16 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  68. Assessment of Haemodynamic Response to Nonselective Beta-Blockers in Portal Hypertension by Phase-Contrast Magnetic Resonance Angiography

    Mcdonald, N., Lilburn, D. M. L., Lachlan, N. J., Macnaught, G., Patel, D., Jayaswal, A. N. A., Hayes, P. C., Semple, S. I. & Fallowfield, J. A., 15 Jun 2017, In: BioMed Research International. 2017, p. 1-8

    Research output: Contribution to journalArticlepeer-review

  69. KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes

    Koulaouzidis, A., Iakovidis, D. K., Yung, D. E., Rondonotti, E., Kopylov, U., Toth, E., Eliakim, A., Wurm Johansson, G., Marlicz, W., Mavrogenis, G., Nemeth, A., Thorlacius, H., Tontini, G. E. & Plevris, J., Jun 2017, In: Endoscopy International Open. 5, 6, p. E477-E483

    Research output: Contribution to journalArticlepeer-review

  70. Small bowel malignancy in patients undergoing capsule endoscopy at a tertiary care academic center: Case series and review of the literature

    Johnston, C. A., Yung, D. E., Joshi, A., Plevris, J. N. & Koulaouzidis, A., Jun 2017, In: Endoscopy International Open. 5, 6, p. E463-E470

    Research output: Contribution to journalArticlepeer-review

  71. Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose–response meta-analysis

    Kennedy, O. J., Roderick, P., Buchanan, R., Fallowfield, J. A., Hayes, P. C. & Parkes, J., 9 May 2017, In: BMJ Open. 7, 5, 14 p., e013739.

    Research output: Contribution to journalArticlepeer-review

  72. EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure

    European Association for the Study of the Liver, 1 May 2017, In: Journal of Hepatology. 66, 5, p. 1047-1081

    Research output: Contribution to journalArticlepeer-review

  73. Reply to the Letter to the Editor

    Sinha, R., Lockman, K. A., Plevris, J. N. & Hayes, P. C., 20 Apr 2017, In: Journal of Hepatology.

    Research output: Contribution to journalComment/debatepeer-review

  74. Multicentre European study of double balloon enteroscopy for small bowel pathology in patients with cardiovascular disease

    Raju, S. A., Ching, H-L., Branchi, F., Yung, D., Koulaouzidis, A., Plevris, J. N., Elli, L., Sanders, D. S. & Sidhu, R., 7 Mar 2017, In: Expert Review of Gastroenterology and Hepatology. 11, 5, p. 391-392 2 p.

    Research output: Contribution to journalLetterpeer-review

  75. Modelling the impact of incarceration and prison-based HCV treatment on HCV transmission among people who inject drugs in Scotland

    Stone, J., Martin, N., Hickman, M., Hutchinson, S., Aspinall, E. J., Taylor, A., Munro, A., Dunleavy, K., Peters, E., Bramley, P., Hayes, P., Goldberg, D. & Vickerman, P., 3 Mar 2017, In: Addiction.

    Research output: Contribution to journalArticlepeer-review

  76. Macroscopic findings in collagenous colitis: a multi-center, retrospective, observational cohort study

    Koulaouzidis, A., Yung, D. E., Nemeth, A., Sjöberg, K., Giannakou, A., Qureshi, R., Bartzis, L., McNeill, M., Johansson, G. W., Lucendo, A. J., Fineron, P., Trimble, K. C., Saeed, A., Plevris, J. & Toth, E., 20 Feb 2017, In: Annals of Gastroenterology. 30, 3, p. 309-314 6 p.

    Research output: Contribution to journalArticlepeer-review

  77. Acute liver failure in Scotland: Changes in aetiology and outcomes over time (The Scottish Look-Back Study).

    Donnelly, M., Davidson, J. S., Martin, K., Baird, A., Hayes, P. & Simpson, K., 17 Feb 2017, In: Alimentary Pharmacology and Therapeutics. 45, 6

    Research output: Contribution to journalArticlepeer-review

  78. Carvedilol is associated with improved survival in patients with liver cirrhosis and ascites

    Sinha, R., Lockman, K. A., Mallawaarachchi, N., Robertson, M., Plevris, J. & Hayes, P. C., 14 Feb 2017, In: Journal of Hepatology.

    Research output: Contribution to journalArticlepeer-review

  79. Clinical outcomes of negative small bowel capsule endoscopy for small bowel bleeding- a systematic review and meta-analysis.

    Yung, D., Koulaouzidis, A., Avni, T., Kopylov, U., Giannakou, A., Rondonotti, E., Pennazio, M., Eliakim, R. & Plevris, J., Feb 2017, In: Gastrointestinal Endoscopy. 85, 2

    Research output: Contribution to journalArticlepeer-review

  80. Patients with the worst outcomes after paracetamol (acetaminophen)-induced liver failure have an early monocytopenia

    Moore, J. K., MacKinnon, A. C., Man, T. Y., Manning, J. R., Forbes, S. J. & Simpson, K. J., Feb 2017, In: Alimentary Pharmacology and Therapeutics.

    Research output: Contribution to journalArticlepeer-review

  81. Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver

    Gamal, W., Treskes, P., Samuel, K., Sullivan, G. J., Siller, R., Srsen, V., Morgan, K., Bryans, A., Kozlowska, A., Koulovasilopoulos, A., Underwood, I., Smith, S., del-Pozo, J., Moss, S., Thompson, A. I., Henderson, N. C., Hayes, P. C., Plevris, J. N., Bagnaninchi, P-O. & Nelson, L. J., 30 Jan 2017, In: Scientific Reports. 7, 16 p., 37541 .

    Research output: Contribution to journalArticlepeer-review

  82. Clinical validity of flexible spectral imaging color enhancement (FICE) in small-bowel capsule endoscopy: a systematic review and meta-analysis

    Yung, D., Boal Carvalho, P., Giannakou, A., Kopylov, U., Rosa, B., Rondonotti, E., Toth, E., Plevris, J. & Koulaouzidis, A., 25 Jan 2017, In: Endoscopy. 49, 03, p. 258-269

    Research output: Contribution to journalArticlepeer-review

  83. Systematic review and meta-analysis of the performance of nurses in small bowel capsule endoscopy reading

    Yung, D., Fernandez-Urien, I., Douglas, S., Plevris, J., Sidhu, R., McAlindon, M., Panter, S. & Koulaouzidis, A., 11 Jan 2017, In: United European Gastroenterology Journal.

    Research output: Contribution to journalArticlepeer-review

  84. 2016
  85. The impact of proton pump inhibitor therapy on patients with liver disease

    Cole, H. L., Pennycook, S. & Hayes, P., Dec 2016, In: Alimentary Pharmacology and Therapeutics. 44, 11

    Research output: Contribution to journalArticlepeer-review

  86. Prognosis of 1169 hepatitis C chronically infected patients with decompensated cirrhosis in the predirect-acting antiviral era

    McDonald, S. A., Innes, H., Aspinall, E. J., Hayes, P., Alavi, M., Valerio, H., Goldberg, D. J. & Hutchinson, S. J., 25 Nov 2016, In: Journal of Viral Hepatitis.

    Research output: Contribution to journalArticlepeer-review

  87. Development and validation of a dynamic outcome prediction model for paracetamol-induced acute liver failure: a cohort study

    Bernal, W., Wang, Y., Maggs, J., Willars, C., Sizer, E., Auzinger, G., Murphy, N., Harding, D., Elsharkawy, A., Simpson, K., Larsen, F. S., Heaton, N., O'Grady, J., Williams, R. & Wendon, J., 1 Nov 2016, In: Lancet Gastroenterology and Hepatology. 1, 3, p. 217-225 9 p.

    Research output: Contribution to journalArticlepeer-review

  88. Double-balloon colonoscopy for failed conventional colonoscopy: the Edinburgh experience and systematic review of existing data

    Yung, D. E., Koulaouzidis, A., Fraser, C., Trimble, K. C. & Plevris, J. N., Nov 2016, In: Gastrointestinal Endoscopy. 84, 5, p. 878-881 4 p.

    Research output: Contribution to journalLetterpeer-review

  89. Fecal calprotectin for the prediction of small-bowel Crohn’s disease by capsule endoscopy: a systematic review and meta-analysis

    Kopylov, U., Yung, D., Engel, T., Avni, T., Battat, R., Ben-Horin, S., Plevris, J. N., Eliakim, R. & Koulaouzidis, A., Oct 2016, In: European Journal of Gastroenterology & Hepatology.

    Research output: Contribution to journalArticlepeer-review

  90. Mortality in hepatitis C patients who achieve a sustained viral response compared to the general population

    Innes, H., McDonald, S., Hayes, P., Dillon, J. F., Allen, S., Goldberg, D., Mills, P. R., Barclay, S. T., Wilks, D., Valerio, H., Fox, R., Bhattacharyya, D., Kennedy, N., Morris, J., Fraser, A., Stanley, A., Bramley, P. & Hutchinson, S. J., 18 Aug 2016, In: Journal of Hepatology.

    Research output: Contribution to journalArticlepeer-review

  91. Hepatitis C reinfection following treatment induced viral clearance among people who have injected drugs.

    Weir, A., McLeod, A., Innes, H., Valerio, H., Aspinall, E., Goldberg, D., Barclay, S. T., Dillon, J. F., Fox, R., Fraser, A., Hayes, P., Kennedy, N., Mills, P. R., Stanley, A. J., Aitken, C., Gunson, R., Templeton, K., Hunt, A., McINTYRE, P. & Hutchinson, SJ., Aug 2016, In: Drug and Alcohol Dependence. 165

    Research output: Contribution to journalArticlepeer-review

  92. Role of inflammation and infection in the pathogenesis of human acute liver failure: Clinical implications for monitoring and therapy

    Donnelly, M. C., Hayes, P. C. & Simpson, K. J., 14 Jul 2016, In: World journal of gastroenterology : WJG. 22, 26, p. 5958-70 13 p.

    Research output: Contribution to journalArticlepeer-review

  93. Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro

    Lockman, K. A., Htun, V., Sinha, R., Treskes, P., Nelson, L. J., Martin, S. F., Rogers, S. M., Le Bihan, T., Hayes, P. C. & Plevris, J. N., 2 Jul 2016, In: Lipids in Health and Disease. 15, 1, 114.

    Research output: Contribution to journalArticlepeer-review

  94. Alpha-Fetoprotein Detection of Hepatocellular Carcinoma Leads to a Standardized Analysis of Dynamic AFP to Improve Screening Based Detection

    Bird, T. G., Dimitropoulou, P., M Turner, R., Jenks, S., Cusack, P., Hey, S., Blunsum, A., Kelly, S., Sturgeon, C. M., Hayes, P. C. & Bird, S. M., 16 Jun 2016, In: PLoS ONE.

    Research output: Contribution to journalArticlepeer-review

  95. Human hepatic HepaRG cells maintain an organotypic phenotype with high intrinsic CYP450 activity/metabolism and significantly outperform standard HepG2/C3A cells for pharmaceutical and therapeutic applications

    Nelson, L., Morgan, K., Treskes, P., Samuel, K., Henderson, C. J., LeBled, C., Homer, N., Grant, M. H., Hayes, P. C. & Plevris, J., 10 Jun 2016, In: Basic and Clinical Pharmacology and Toxicology.

    Research output: Contribution to journalArticlepeer-review

  96. Anticipated Regret and Organ Donor Registration: a randomised controlled trial

    O'Carroll, R. E., Shepherd, L., Hayes, P. & Ferguson, E., 9 Jun 2016, In: Health Psychology. 35, 11

    Research output: Contribution to journalArticlepeer-review

  97. Differential visceral blood flow in the hyperdynamic circulation of patients with liver cirrhosis

    McAvoy, N., Semple, S., Richards, JMJ., Robson, AJ., Patel, D., Jardine, AGM., Leyland, K., Cooper, AS., Newby, D. & Hayes, P., May 2016, In: Alimentary Pharmacology and Therapeutics.

    Research output: Contribution to journalArticlepeer-review

  98. The use of hemostatic spray as an adjunct to the conventional hemostatic measures in high-risk nonvariceal upper GI bleeding (with video)

    Sinha, R., Lockman, K. A., Church, N. I., Plevris, J. N. & Hayes, P. C., 21 Apr 2016, In: Gastrointestinal Endoscopy.

    Research output: Contribution to journalArticlepeer-review

  99. Reducing hepatocyte injury and necrosis in response to paracetamol using non-coding RNAs

    Szkolnicka, D., Lucendo Villarin, B., Moore, J., Simpson, K. J., Forbes, S. J. & Hay, D. C., 7 Apr 2016, In: Stem Cells Translational Medicine.

    Research output: Contribution to journalArticlepeer-review

  100. Small bowel capsule endoscopy and portal hypertensive enteropathy in cirrhotic patients: results from a tertiary referral centre

    Dabos, K. J., Yung, D. E., Bartzis, L., Hayes, P. C., Plevris, J. N. & Koulaouzidis, A., 7 Apr 2016, In: Annals of hepatology. 15, 3, p. 394-401 8 p.

    Research output: Contribution to journalArticlepeer-review

  101. The Changing Face of Liver Transplantation for Acute Liver Failure: Assessment of Current Status and Implications for Future Practice.

    Donnelly, M. C., Hayes, P. & Simpson, K. J., Apr 2016, In: Liver Transplantation.

    Research output: Contribution to journalArticlepeer-review

  102. Systematic review with meta‐analysis: coffee consumption and the risk of cirrhosis

    Kennedy, O. J., Roderick, P., Buchanan, R., Fallowfield, J. A., Hayes, P. C. & Parkes, J., Mar 2016, In: Alimentary Pharmacology and Therapeutics. 43, 5, p. 562-574

    Research output: Contribution to journalArticlepeer-review

  103. 2015
  104. The prevalence and impact of thrombocytopenia, anaemia and leucopenia on sustained virological response in patients receiving hepatitis C therapy: evidence from a large 'real world' cohort.

    Wang, H., Innes, H., Hutchinson, SJ., Goldberg, DJ., Allen, S., Barclay, ST., Bramley, P., Fox, R., Fraser, A., Hayes, P., Kennedy, N., Mills, P. R. & Dillon, J. F., 21 Dec 2015, In: European Journal of Gastroenterology & Hepatology.

    Research output: Contribution to journalArticlepeer-review

  105. Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model

    Nelson, L. J., Navarro, M., Treskes, P., Samuel, K., Tura-Ceide, O., Morley, S. D., Hayes, P. C. & Plevris, J. N., 3 Dec 2015, In: Scientific Reports. 5, 17455 .

    Research output: Contribution to journalArticlepeer-review

  106. CSF1 Restores Innate Immunity Following Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

    Stutchfield, B. M., Antoine, D. J., MacKinnon, A. C., Gow, D. J., Bain, C. C., Hawley, C. A., Hughes, M., Francis, B., Wojtacha, D., Man, T. Y., Dear, J. W., Devey, L. R., Mowat, A., Pollard, J. W., Park, B. K., Jenkins, S. J., Simpson, K. J., Hume, D. A., Wigmore, S. J. & Forbes, S. J., 1 Dec 2015, In: Gastroenterology. 149, 7, p. 1896-1909 14 p.

    Research output: Contribution to journalArticlepeer-review

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