Edinburgh Research Explorer

Small Vessel Disease Research

Organisational unit: Research Group

  1. 1993
  2. Does early reperfusion of a cerebral infarct influence cerebral infarct swelling in the acute stage or the final clinical outcome?

    Wardlaw, J. M., Dennis, M. S., Lindley, R. I., Warlow, C. P., Sandercock, P. A. G. & Sellar, R., 1993, In: Cerebrovascular diseases. 3, 2, p. 86-93 8 p.

    Research output: Contribution to journalArticlepeer-review

  3. 2006
  4. Central periodic breathing observed on hospital admission is associated with an adverse prognosis in conscious acute stroke patients

    Rowat, A. M., Dennis, M. S. & Wardlaw, J. M., 2006, In: Cerebrovascular diseases. 21, 5-6, p. 340-7 8 p.

    Research output: Contribution to journalArticlepeer-review

  5. Designing for e-Health: recurring scenarios in developing grid-based medical imaging systems

    Geddes, J., Mackay, C., Lloyd, S., Simpson, A., Power, D., Russell, D., Jirotka, M., Katzarova, M., Rossor, M., Fox, N., Fletcher, J., Hill, D., McLeish, K., Chen, Y., Hajnal, J. V., Lawrie, S., Job, D., McIntosh, A., Wardlaw, J., Sandercock, P. & 11 others, Palmer, J., Perry, D., Procter, R., Ure, J., Hartswood, M., Slack, R., Voss, A., Ho, K., Bath, P., Clarke, W. & Watson, G., 2006, In: Stud Health Technol Inform. 120, p. 336-47 12 p.

    Research output: Contribution to journalArticlepeer-review

  6. Distinguishing between stroke and mimic at the bedside: the brain attack study

    Hand, P. J., Kwan, J., Lindley, R. I., Dennis, M. S. & Wardlaw, J. M., 2006, In: Stroke; a journal of cerebral circulation. 37, 3, p. 769-75 7 p.

    Research output: Contribution to journalArticlepeer-review

  7. Do acute diffusion- and perfusion-weighted MRI lesions identify final infarct volume in ischemic stroke?

    Rivers, C. S., Wardlaw, J. M., Armitage, P. A., Bastin, M. E., Carpenter, T. K., Cvoro, V., Hand, P. J. & Dennis, M. S., 2006, In: Stroke; a journal of cerebral circulation. 37, 1, p. 98-104 7 p.

    Research output: Contribution to journalArticlepeer-review

  8. Genetic Programming for Prediction of Fat Content in Meat Images

    Ballerini, L. & Bocchi, L., 2006, GSICE. Vol. 11. p. 12 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  9. Hypoxaemia in acute stroke is frequent and worsens outcome

    Rowat, A. M., Dennis, M. S. & Wardlaw, J. M., 2006, In: Cerebrovascular diseases (Basel, Switzerland). 21, 3, p. 166-72 7 p.

    Research output: Contribution to journalArticlepeer-review

  10. Image space colonization algorithm

    Bocchi, L. & Ballerini, L., 2006, Applications of Evolutionary Computing. Springer Berlin Heidelberg, p. 356-367 12 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  11. Interobserver agreement for the bedside clinical assessment of suspected stroke

    Hand, P. J., Haisma, J. A., Kwan, J., Lindley, R. I., Lamont, B., Dennis, M. S. & Wardlaw, J. M., 2006, In: Stroke. 37, 3, p. 776-80 5 p.

    Research output: Contribution to journalArticlepeer-review

  12. Interobserver agreement in magnetic resonance brain and neck imaging

    Colledge, N., Sellar, R., Wardlaw, J., Lewis, S., Mead, G. & Wilson, J., 2006, In: Journal of Neuroimaging. 16, 1, p. 47-51 5 p.

    Research output: Contribution to journalArticlepeer-review

  13. MR diffusion-weighted imaging and outcome prediction after ischemic stroke

    Hand, P. J., Wardlaw, J. M., Rivers, C. S., Armitage, P. A., Bastin, M. E., Lindley, R. I. & Dennis, M. S., 2006, In: Neurology. 66, 8, p. 1159-63 5 p.

    Research output: Contribution to journalArticlepeer-review

  14. Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke

    Karaszewski, B., Wardlaw, J. M., Marshall, I., Cvoro, V., Wartolowska, K., Haga, K., Armitage, P. A., Bastin, M. E. & Dennis, M. S., 2006, In: Annals of Neurology. 60, 4, p. 438-46 9 p.

    Research output: Contribution to journalArticlepeer-review

  15. No evidence that severity of stroke in internal carotid occlusion is related to collateral arteries

    Mead, G. E., Wardlaw, J. M., Lewis, S. C., Dennis, M. S. & Lothian Stroke Registry Study Group, 2006, In: Journal of Neurology, Neurosurgery & Psychiatry. 77, 6, p. 729-33 5 p.

    Research output: Contribution to journalArticlepeer-review

  16. Quantification of Bone Tissue Integration--a Comparative Study of Histomorphometrical Data

    Ballerini, L., Franke-Stenport, V., Johansson, C. B., Hoffman, M. & Boregfors, G., 2006.

    Research output: Contribution to conferencePaperpeer-review

  17. Third international stroke trial

    Whiteley, W., Lindley, R., Wardlaw, J., Sandercock, P. & IST-3 Collaborative Group, 2006, In: International Journal of Stroke. 1, 3, p. 172-6 5 p.

    Research output: Contribution to journalArticlepeer-review

  18. Uncertainties about thrombolysis for stroke should be addressed with large-scale randomized trials

    Whiteley, W., Sandercock, P., Wardlaw, J. & Lindley, R., 2006, In: Stroke; a journal of cerebral circulation. 37, 11, p. 2662; author reply 2664-5

    Research output: Contribution to journalArticlepeer-review

  19. White matter integrity and cognition in childhood and old age

    Deary, I. J., Bastin, M. E., Pattie, A., Clayden, J. D., Whalley, L. J., Starr, J. & Wardlaw, J. M., 28 Feb 2006, In: Neurology. 66, 4, p. 505-512 8 p.

    Research output: Contribution to journalArticlepeer-review

  20. A pilot study of brain tumour growth between radiotherapy planning and delivery

    Pennington, C., Kilbride, L., Grant, R. & Wardlaw, J. M., Mar 2006, In: Clinical Oncology. 18, 2, p. 104-8 5 p.

    Research output: Contribution to journalArticlepeer-review

  21. Smaller left anterior cingulate cortex volumes are associated with impaired hypothalamic-pituitary-adrenal axis regulation in healthy elderly men

    MacLullich, A. M. J., Ferguson, K. J., Wardlaw, J. M., Starr, J. M., Deary, I. J. & Seckl, J. R., Apr 2006, In: Journal of Clinical Endocrinology & Metabolism. 91, 4, p. 1591-1594 4 p.

    Research output: Contribution to journalArticlepeer-review

  22. Non-invasive imaging compared with intra-arterial angiography in the diagnosis of symptomatic carotid stenosis: a meta-analysis

    Wardlaw, J. M., Chappell, F. M., Best, J. J. K., Wartolowska, K., Berry, E. & NHS Research and Development Health Technology Assessment Carotid Stenosis Imaging Group, 6 May 2006, In: The Lancet. 367, 9521, p. 1503-12 10 p.

    Research output: Contribution to journalArticlepeer-review

  23. Persistent infarct hyperintensity on diffusion-weighted imaging late after stroke indicates heterogeneous, delayed, infarct evolution

    Rivers, C. S., Wardlaw, J. M., Armitage, P. A., Bastin, M. E., Carpenter, T. K., Cvoro, V., Hand, P. J. & Dennis, M. S., Jun 2006, In: Stroke; a journal of cerebral circulation. 37, 6, p. 1418-23 6 p.

    Research output: Contribution to journalArticlepeer-review

  24. Measurement of regional brain temperature using proton spectroscopic imaging: validation and application to acute ischemic stroke

    Marshall, I., Karaszewski, B., Wardlaw, J. M., Cvoro, V., Wartolowska, K., Armitage, P. A., Carpenter, T., Bastin, M. E., Farrall, A. & Haga, K., Jul 2006, In: Magnetic Resonance Imaging. 24, 6, p. 699-706 8 p.

    Research output: Contribution to journalArticlepeer-review

  25. Cerebral microbleeds are associated with lacunar stroke defined clinically and radiologically, independently of white matter lesions

    Wardlaw, J. M., Lewis, S. C., Keir, S. L., Dennis, M. S. & Shenkin, S., 31 Aug 2006, In: Stroke; a journal of cerebral circulation. 37, 10, p. 2633-6 4 p.

    Research output: Contribution to journalArticlepeer-review

  26. Multidimensional filtering approaches for pre-processing thermal images

    Valdes Hernandez, M., Inamura, M., Valera, J. D. R. & Lu, Y., 24 Oct 2006, In: Multidimensional Systems and Signal Processing. 17, 4, p. 299-325

    Research output: Contribution to journalArticlepeer-review

  27. The challenges of developing a collaborative data and compute grid for neurosciences

    Geddes, J., Mackay, C., Lloyd, S., Simpson, A., Power, D., Russell, D., Katzarova, M., Rossor, M., Fox, N., Fletcher, J., Hill, D., McLeish, K., Hajnal, J. V., Lawrie, S., Job, D., McIntosh, A., Wardlaw, J., Sandercock, P., Palmer, J., Perry, D. & 4 others, Procter, R., Ure, J., Bath, P. & Watson, G., 22 Dec 2006, Proceedings - 19th IEEE International Symposium on Computer-Based Medical Systems, CBMS 2006. Vol. 2006. p. 81-86 6 p. 1647550

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  28. 2007
  29. Abnormal breathing patterns in stroke: relationship with location of acute stroke lesion and prior cerebrovascular disease

    Rowat, A. M., Wardlaw, J. M. & Dennis, M. S., 2007, In: Journal of Neurology, Neurosurgery & Psychiatry. 78, 3, p. 277-9 3 p.

    Research output: Contribution to journalArticlepeer-review

  30. Acute ischemic stroke lesion measurement on diffusion-weighted imaging--important considerations in designing acute stroke trials with magnetic resonance imaging

    Rivers, C. S., Wardlaw, J. M., Armitage, P. A., Bastin, M. E., Hand, P. J. & Dennis, M. S., 2007, In: Journal of Stroke and Cerebrovascular Diseases. 16, 2, p. 64-70 7 p.

    Research output: Contribution to journalArticlepeer-review

  31. Automatic 3D Modeling of Skulls by Scatter Search and Heuristic Features

    Ballerini, L., Cordón, O., Damas, S. & Santamaria, J., 2007, 12th On-line World Conference on Soft Computing in Industrial Applications.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  32. Comparison of histomorphometrical data obtained with two different image analysis methods

    Ballerini, L., Franke-Stenport, V., Borgefors, G. & Johansson, C. B., 2007, In: Journal of Materials Science: Materials in Medicine. 18, 8, p. 1471-1479 9 p.

    Research output: Contribution to journalArticlepeer-review

  33. Craniofacial superimposition in forensic identification using genetic algorithms

    Ballerini, L., Cordon, O., Santamaria, J., Damas, S., Aleman, I. & Botella, M., 2007, Information Assurance and Security, 2007. IAS 2007. Third International Symposium on. p. 429-434 6 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  34. DTI and MTI parameters correlate in periventricular white matter hyperintensities in old age

    Bastin, M., Clayden, J. D. & Wardlaw, J., 2007, ISMRM-ESMRMB Joint Annual Meeting, Berlin.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  35. Data integration in eHealth: a domain/disease specific roadmap

    Ure, J., Procter, R., Martone, M., Porteous, D., Lloyd, S., Lawrie, S., Job, D., Baldock, R., Philp, A., Liewald, D., Rakebrandt, F., Blaikie, A., McKay, C., Anderson, S., Ainsworth, J., van Hemert, J., Blanquer, I., Sinnott, R., Barillot, C., Gibaud, F. B. & 17 others, Williams, A., Hartswood, M., Watson, P., Smith, L., Burger, A., Kennedy, J., Gonzalez-Velez, H., Stevens, R., Corcho, O., Morton, R., Linksted, P., Deschenes, M., McGilchrist, M., Johnson, P., Voss, A., Gertz, R. & Wardlaw, J., 2007, From Genes to Personalized HealthCare: Grid Solutions for the Life Sciences. Vol. 126. p. 144-53 10 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  36. Data integration in eHealth: a domain/disease specific roadmap

    Ure, J., Procter, R., Martone, M., Porteous, D., Lloyd, S., Lawrie, S., Job, D., Baldock, R., Philp, A., Liewald, D., Rakebrandt, F., Blaikie, A., McKay, C., Anderson, S., Ainsworth, J., van Hemert, J., Blanquer, I., Sinnott, R., Barillot, C., Gibaud, F. B. & 17 others, Williams, A., Hartswood, M., Watson, P., Smith, L., Burger, A., Kennedy, J., Gonzalez-Velez, H., Stevens, R., Corcho, O., Morton, R., Linksted, P., Deschenes, M., McGilchrist, M., Johnson, P., Voss, A., Gertz, R. & Wardlaw, J., 2007, In: Stud Health Technol Inform. 126, p. 144-153 10 p.

    Research output: Contribution to journalArticlepeer-review

  37. Genetic snakes: Active contour models by genetic algorithms

    Ballerini, L., 2007, Genetic and evolutionary computation in image processing and computer vision. p. 177-194 18 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  38. Selección heuristica en imágenes 3D para la reconstrucción forense de cráneos con búsqueda dispersa

    Ballerini, L., Cordón, Ó., Damas, S. & Santamaria, J., 2007, In: Actas de las I Jornadas sobre Algoritmos Evolutivos y Metaheurísticas .

    Research output: Contribution to journalArticlepeer-review

  39. Skull size and intelligence, and King Robert Bruce's IQ

    Deary, I. J., Ferguson, K. J., Bastin, M. E., Barrow, G. W. S., Reid, L. M., Seckl, J. R., Wardlaw, J. M. & MacLullich, A. M. J., 2007, In: Intelligence. 35, 6, p. 519-525 7 p.

    Research output: Contribution to journalArticlepeer-review

  40. Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting

    Cordonnier, C., Al-Shahi Salman, R. & Wardlaw, J., 2007, In: Brain. 130, Pt 8, p. 1988-2003 16 p.

    Research output: Contribution to journalArticlepeer-review

  41. The NeuroGrid stroke exemplar clinical trial protocol

    Wardlaw, J. M., Bath, P., Sandercock, P., Perry, D., Palmer, J., Watson, G., Lloyd, S., Geddes, J. & Farrall, A., 2007, In: International Journal of Stroke. 2, 1, p. 63-9 7 p.

    Research output: Contribution to journalArticlepeer-review

  42. Factors influencing the detection of early CT signs of cerebral ischemia: an internet-based, international multiobserver study

    Wardlaw, J. M., Farrall, A. J., Perry, D., von Kummer, R., Mielke, O., Moulin, T., Ciccone, A., Hill, M. & Acute Cerebral CT Evaluation of Stroke Study (ACCESS) Study Group, Apr 2007, In: Stroke; a journal of cerebral circulation. 38, 4, p. 1250-6 7 p.

    Research output: Contribution to journalArticlepeer-review

  43. A prospective, multicentre study to investigate the efficacy, safety and tolerability of octreotide LAR (long-acting repeatable octreotide) in the primary therapy of patients with acromegaly

    Mercado, M., Borges, F., Bouterfa, H., Chang, T-C., Chervin, A., Farrall, A. J., Patocs, A., Petersenn, S., Podoba, J., Safari, M., Wardlaw, J. & SMS995B2401 Study Group, Jun 2007, In: Clinical Endocrinology. 66, 6, p. 859-68 10 p.

    Research output: Contribution to journalArticlepeer-review

  44. Long-term visibility of primary intracerebral hemorrhage on magnetic resonance imaging

    Dimigen, M., Keir, S., Dennis, M. & Wardlaw, J., 2 Oct 2007, In: Journal of Stroke and Cerebrovascular Diseases. 13, 3, p. 104-8 5 p.

    Research output: Contribution to journalArticlepeer-review

  45. 2008
  46. Automatic 3D skull reconstruction using invariant features

    Ballerini, L., Calisti, M., Damas, S., Cordón, O. & Santamaria, J., 2008, Proceedings of the 5th international conference on Soft computing as transdisciplinary science and technology. p. 444-449 6 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  47. Automatic feature extraction from 3D range images of skulls

    Ballerini, L., Calisti, M., Cordón, O., Damas, S. & Santamaria, J., 2008, Computational Forensics. Springer Berlin Heidelberg, p. 58-69 12 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  48. Availability of CT and MR for assessing patients with acute stroke

    Kane, I., Whiteley, W. N., Sandercock, P. A. G. & Wardlaw, J. M., 2008, In: Cerebrovascular diseases (Basel, Switzerland). 25, 4, p. 375-7 3 p.

    Research output: Contribution to journalArticlepeer-review

  49. EPITHET--where next?

    Sandercock, P., Wardlaw, J., Dennis, M., Lindley, R., Hankey, G., Matz, K., Peeters, A., Phillips, S., Gubitz, G., Prasad, K., Ricci, S., Celani, M. G., Righetti, E., Cantisani, T., Arauz, A., Berge, E., Slot, K. B., Kobayashi, A., Czlonkowska, A., Correia, M. & 4 others, Murray, V., Lyrer, P., Venables, G. & IST-3 Collaborative Group, 2008, In: Lancet Neurology. 7, 7, p. 570-1; author reply 571-3

    Research output: Contribution to journalArticlepeer-review

  50. Retinal microvascular signs: a key to understanding the underlying pathophysiology of different stroke subtypes

    Lindley, R. & Multi-Centre Retinal Stroke Study Collaborative Group., 2008, In: International Journal of Stroke. 3, p. 297-305

    Research output: Contribution to journalArticlepeer-review

  51. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke

    ECASS Investigators, 2008, In: New England Journal of Medicine. 359, p. 1317-1329

    Research output: Contribution to journalArticlepeer-review

  52. Changes in background blood-brain barrier integrity between lacunar and cortical ischemic stroke subtypes

    Wardlaw, J. M., Farrall, A., Armitage, P. A., Carpenter, T., Chappell, F., Doubal, F., Chowdhury, D., Cvoro, V. & Dennis, M. S., Apr 2008, In: Stroke. 39, 4, p. 1327-1332 6 p.

    Research output: Contribution to journalArticlepeer-review

  53. Evidence of shared white matter disruption in bipolar disorder and sschizophrenia

    McIntosh, A. M., Sussmann, J., Lymer, G. K. S., Munoz-Maniega, S., Bastin, M., Hall, J., Lawrie, S., Johnstone, E., Clayden, J., Job, D. & Moorhead, T. W. J., Apr 2008, In: European Psychiatry. 23, p. S43-S43 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  54. Assessing the impact of the requirement for explicit consent in a hospital-based stroke study

    Jackson, C., Crossland, L., Dennis, M., Wardlaw, J. & Sudlow, C., 1 Apr 2008, In: QJM: An International Journal of Medicine. 101, 4, p. 281-289 9 p.

    Research output: Contribution to journalArticlepeer-review

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