Edinburgh Research Explorer

Small Vessel Disease Research

Organisational unit: Research Group

  1. 2020
  2. Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study

    Beaudet, G., Tsuchida, A., Petit, L., Tzourio, C., Caspers, S., Schreiber, J., Pausova, Z., Patel, Y., Paus, T., Schmidt, R., Pirpamer, L., Sachdev, P. S., Brodaty, H., Kochan, N. A., Trollor, J. N., Wen, W., Armstrong, N. J., Deary, I., Bastin, M., Wardlaw, J. & 6 others, Muñoz Maniega, S., Witte, A. V., Villringer, A., Duering, M., Debette, S. & Mazoyer, B., 4 May 2020, In: Frontiers in psychiatry. 11, 342.

    Research output: Contribution to journalArticlepeer-review

  3. Intracranial haemodynamic relationships in patients with cerebral small vessel disease

    Blair, G., Thrippleton, M., Shi, Y., Hamilton, I., Stringer, M., Chappell, F., Dickie, D. A., Andrews, P., Marshall, I., Doubal, F. & Wardlaw, J., May 2020, In: Neurology. 94, 21

    Research output: Contribution to journalArticlepeer-review

  4. Protocol: The Lacunar Intervention Trial 2 (LACI-2). A trial of two repurposed licenced drugs to prevent progression of cerebral small vessel disease

    Wardlaw, J., Bath, P. M. W., Doubal, F., Heye, A., Sprigg, N., Woodhouse, L. J., Blair, G., Appleton, J., Cvoro, V., England, T., Hassan, A., John Werring, D. & Montgomery, A., 20 Apr 2020, In: European Stroke Journal. p. 239698732092011

    Research output: Contribution to journalArticlepeer-review

  5. Improving Clinical Detection of Acute Lacunar Stroke: Analysis From the IST-3

    Arba, F., Mair, G., Phillips, S., Sandercock, P. & Wardlaw, J. M., 9 Apr 2020, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  6. Relationship Between Venules and Perivascular Spaces in Sporadic Small Vessel Diseases

    Jochems, A. C. C., Blair, G. W., Stringer, M. S., Thrippleton, M. J., Clancy, U., Chappell, F. M., Brown, R., Jaime Garcia, D., Hamilton, O. K. L., Morgan, A. G., Marshall, I., Hetherington, K., Wiseman, S., Macgillivray, T., Valdés-hernández, M. C., Doubal, F. N. & Wardlaw, J. M., 8 Apr 2020, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  7. Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND

    McHutchison, C. A., Leighton, D. J., McIntosh, A., Cleary, E., Warner, J., Porteous, M., Chandran, S., Pal, S. & Abrahams, S., 31 Mar 2020, In: Journal of Neurology, Neurosurgery & Psychiatry. 91, 3, p. 245-253 9 p.

    Research output: Contribution to journalArticlepeer-review

  8. Clinical prognosis of FLAIR hyperintense arteries in ischaemic stroke patients: a systematic review and meta-analysis

    Zhou, Z., Malavera, A., Yoshimura, S., Delcourt, C., Mair, G., Al-shahi Salman, R., Demchuk, A. M., Wardlaw, J. M., Lindley, R. I. & Anderson, C. S., 26 Mar 2020, In: Journal of Neurology, Neurosurgery & Psychiatry. p. jnnp-2019-322625

    Research output: Contribution to journalArticlepeer-review

  9. Global and regional development of the human cerebral cortex: Molecular architecture and occupational aptitudes

    ENIGMA Consortium & neuroCHARGE Cognitive Working group, 20 Mar 2020, In: Cerebral Cortex. bhaa035.

    Research output: Contribution to journalArticlepeer-review

  10. The genetic architecture of the human cerebral cortex

    Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Ching, C. R. K., Mcmahon, M. A. B., Shatokhina, N., Zsembik, L. C. P., Thomopoulos, S. I., Zhu, A. H., Strike, L. T., Agartz, I., Alhusaini, S., Almeida, M. A. A., Alnæs, D., Amlien, I. K. & 31 others, Andersson, M., Ard, T., Armstrong, N. J., Ashley-koch, A., Atkins, J. R., Bernard, M., Brouwer, R. M., Buimer, E. E. L., Bülow, R., Bürger, C., Cannon, D. M., Chakravarty, M., Chen, Q., Cheung, J. W., Couvy-duchesne, B., Dale, A. M., Dalvie, S., De Araujo, T. K., De Zubicaray, G. I., De Zwarte, S. M. C., Den Braber, A., Doan, N. T., Dohm, K., Ehrlich, S., Harris, M. A., Luciano, M., Wardlaw, J. M., Doherty, C. P., Bastin, M. E., Deary, I. J. & Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)—Genetics working group, 20 Mar 2020, In: Science. 367, 6484, 14 p., eaay6690.

    Research output: Contribution to journalArticlepeer-review

  11. Opening the floodgates to the brain

    Moss, J. & Williams, A., 13 Mar 2020, Science.

    Research output: Book/ReportCommissioned report

  12. DNA methylation and brain structure and function across the life course: a systematic review

    Wheater, E. N. W., Stoye, D. Q., Cox, S. R., Wardlaw, J. M., Drake, A. J., Bastin, M. E. & Boardman, J. P., 6 Mar 2020, In: Neuroscience and Biobehavioral Reviews.

    Research output: Contribution to journalArticlepeer-review

  13. Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial

    Chataway, J., De Angelis, F., Connick, P., Parker, R. A., Plantone, D., Doshi, A., John, N., Stutters, J., Macmanus, D., Prados Carrasco, F., Barkhof, F., Ourselin, S., Braisher, M., Ross, M., Cranswick, G., Pavitt, S. H., Giovannoni, G., Gandini Wheeler-kingshott, C. A., Hawkins, C., Sharrack, B. & 5 others, Bastow, R., Weir, C. J., Stallard, N., Chandran, S. & MS -SMART Investigators, 1 Mar 2020, In: The Lancet Neurology. 19, 3, p. 214-225

    Research output: Contribution to journalArticlepeer-review

  14. Polygenic architecture of human neuroanatomical diversity

    Biton, A., Traut, N., Poline, J. B., Aribsala, B., Bastin, M., Bülow, R., Cox, S., Deary, I., Fukunaga, M., Grabe, H. J., Hagenaars, S., Hashimoto, R., Kikuchi, M., Muñoz Maniega, S., Nauck, M., Royle, N., Teumer, A., Valdes Hernandez, M., Völker, U., Wardlaw, J. & 4 others, Wittfield, K., Yamamori, H., Bourgeron, T. & Toro, R., 28 Feb 2020, In: Cerebral Cortex. bhz241.

    Research output: Contribution to journalArticlepeer-review

  15. Publisher Correction: Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

    Koundal, S., Elkin, R., Nadeem, S., Xue, Y., Constantinou, S., Sanggaard, S., Liu, X., Monte, B., Xu, F., Nostrand, W. V., Nedergaard, M., Lee, H., Wardlaw, J., Benveniste, H. & Tannenbaum, A., 27 Feb 2020, In: Scientific Reports. 10, 1

    Research output: Contribution to journalArticle

  16. Perivascular spaces in the brain: anatomy, physiology and pathology

    Wardlaw, J. M., Benveniste, H., Nedergaard, M., Zlokovic, B. V., Mestre, H., Lee, H., Doubal, F. N., Brown, R., Ramirez, J., Macintosh, B. J., Tannenbaum, A., Ballerini, L., Rungta, R. L., Boido, D., Sweeney, M., Montagne, A., Charpak, S., Joutel, A., Smith, K. J. & Black, S. E., 24 Feb 2020, In: Nature Reviews Neurology. 16, 3, p. 137-153 17 p.

    Research output: Contribution to journalArticlepeer-review

  17. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In: Nature Communications. 11, 800.

    Research output: Contribution to journalArticlepeer-review

  18. Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

    Kounda, S., Elkin, R., Nadeem, S., Xue, Y., Constantinou, S., Sanggaard, S., Liu, X., Monte, B., Xu, F., Van Nostrand, W., Nedergaard, M., Lee, H., Wardlaw, J., Benveniste, H. & Tannenbaum, A., 6 Feb 2020, In: Scientific Reports. 10, 1

    Research output: Contribution to journalArticlepeer-review

  19. Fluctuating asymmetry in brain structure and general intelligence in 73-Year-olds

    Moodie, J. E., Ritchie, S., Cox, S., Harris, M., Muñoz Maniega, S., Valdes Hernandez, M., Pattie, A., Corley, J., Bastin, M., Starr, J., Wardlaw, J. & Deary, I., 31 Jan 2020, In: Intelligence. 78, 101407.

    Research output: Contribution to journalArticlepeer-review

  20. Analysis of spatial spectral features of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease

    Bernal Moyano, J., Valdes Hernandez, M., Escudero, J., Armitage, P., Makin, S., Touyz, R. M. & Wardlaw, J., 24 Jan 2020, Medical Image Understanding and Analysis. MIUA 2019. Communications in Computer and Information Science. Springer, Vol. 1065.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  21. Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology

    Varsou, O., Turnbull, K., Stringer, M. S., Fernandes, C. D., Murray, A. D., Schwarzbauer, C. & Macleod, M. J., 23 Jan 2020, In: Neurological Sciences.

    Research output: Contribution to journalArticlepeer-review

  22. Cerebral small vessel disease: Potential interventions for prevention and treatment

    Blair, G., Appleton, J. P., Wardlaw, J. & Bath, P., 15 Jan 2020, Stroke in the Older Person. Oxford University Press

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  23. Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow

    Shi, Y., Thrippleton, M. J., Blair, G. W., Dickie, D. A., Marshall, I., Hamilton, I., Doubal, F. N., Chappell, F. & Wardlaw, J. M., 1 Jan 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40, 1, p. 85-99 15 p.

    Research output: Contribution to journalArticlepeer-review

  24. Sleep and brain morphological changes in the eighth decade of life

    Aribisala, B. S., Riha, R. L., Valdes Hernandez, M., Maniega, S. M., Cox, S., Radakovic, R., Taylor, A., Pattie, A., Corley, J., Redmond, P., Bastin, M. E., Starr, J., Deary, I. & Wardlaw, J. M., Jan 2020, In: Sleep medicine. 65

    Research output: Contribution to journalArticlepeer-review

  25. White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed

    Freeze, W. M., Jacobs, H. I. L., De Jong, J. J., Verheggen, I. C. M., Gronenschild, E. H. B. M., Palm, W. M., Hoff, E. I., Wardlaw, J. M., Jansen, J. F. A., Verhey, F. R. & Backes, W. H., Jan 2020, In: Neurobiology of Aging. 85

    Research output: Contribution to journalArticlepeer-review

  26. 2019
  27. The striatum, the hippocampus, and short-term memory binding: Volumetric analysis of the subcortical grey matter's role in mild cognitive impairment

    Valdés Hernández, M. C., Clark, R., Wang, S-H., Guazzo, F., Calia, C., Pattan, V., Starr, J., Della Sala, S. & Parra, M. A., 29 Dec 2019, In: NeuroImage: Clinical. 25, 13 p., 102158.

    Research output: Contribution to journalArticlepeer-review

  28. Imaging markers of small vessel disease and ‘brain frailty’ and outcomes in acute stroke

    Appleton, J. P., Woodhouse, L., Adami, A., Becker, J. L., Berge, E., Cala, L. A., Casado, A. M., Caso, V., Christensen, H., Dineen, R. A., Gommans, J., Koumellis, P., Szatmari, S., Sprigg, N., Bath, P. M., Wardlaw, J. & ENOS Investigators, 27 Dec 2019, In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  29. Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

    Jia, T., Chu, C., Liu, Y., van Dongen, J., Papastergios, E., Armstrong, N. J., Bastin, M. E., Carrillo-roa, T., den Braber, A., Harris, M., Jansen, R., Liu, J., Luciano, M., Ori, A. P. S., Roiz-Santianez, R., Ruggeri, B., Sarkisyan, D., Shin, J., Sungeun, K., Tordesillas-Gutierrez, D. & 62 others, Van't Ent, D., Ames, D., Artiges, E., Bakalkin, G., Banaschewski, T., Bokde, A. L. W., Brodaty, H., Bromberg, U., Brouwer, R. M., Büchel, C., Quinlan, E. B., Cahn, W., de Zubicaray, G. I., Ehrlich, S., Ekström, T. J., Flor, H., Fröhner, J. H., Frouin, V., Garavan, H., Gowland, P. A., Heinz, A., Hoare, J., Ittermann, B., Jahanshad, N., Jiang, J., Kwok, J. B. J., Martin, N. G., Martinot, J-L., Mather, K. A., McMahon, K. L., Mcrae, A. F., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Sämann, P. G., Schofield, P. R., Smolka, M. N., Stein, D. J., Strike, L. T., Teeuw, J., Thalamuthu, A., Trollor, J. N., Walter, H., Wardlaw, J. M., Wen, W., Whelan, R., Apostolova, L. G., Binder, E. B., Boomsma, D., Calhoun, V. D., Crespo-Facorro, B., Deary, I. J., Hulshoff Pol, H. E., Ophoff, R. A., Pausova, Z., Sachdev, P. S., Saykin, A. J., Wright, M. J., Thompson, P. M., Schumann, G. & Desrivières, S., 6 Dec 2019, In: Molecular Psychiatry. N/A, p. 1-12

    Research output: Contribution to journalArticlepeer-review

  30. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R. F., Stevenson, A. J., Cox, S. R., McCartney, D. L., Harris, S. E., Seeboth, A., Higham, J., Sproul, D., Taylor, A. M., Redmond, P., Corley, J., Pattie, A., del C. Valdés Hernández, M., Muñoz-Maniega, S., Bastin, M. E., Wardlaw, J. M., Horvath, S., Ritchie, C. W., Spires-Jones, T. L., McIntosh, A. M. & 3 others, Evans, K. L., Deary, I. J. & Marioni, R. E., 3 Dec 2019, In: Molecular Psychiatry. N/A, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  31. A novel genetic locus influencing retinal venular tortuosity is also associated with risk of coronary artery disease

    Veluchamy, A., Ballerini, L., Vitart, V., Schraut, K. E., Kirin, M., Campbell, H., Joshi, P., Relan, D., Harris, S., Brown, E., Vaidya, S. S., Dhillon, B., Zhou, K., Pearson, E. R., Hayward, C., Polasek, O., Deary, I., MacGillivray, T., Wilson, J., Trucco, E. & 2 others, Palmer, C. N. A. & Doney, A. S. F., Dec 2019, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 12, p. 2542-2552

    Research output: Contribution to journalArticlepeer-review

  32. Retinal microvascular features and cognitive change in the Lothian Birth Cohort 1936

    McGrory, S., Ballerini, L., Okely, J., Ritchie, S., Doubal, F., Doney, A. S. F., Starr, J., MacGillivray, T., Trucco, E., Wardlaw, J. & Deary, I., Dec 2019, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 500-509 10 p.

    Research output: Contribution to journalArticlepeer-review

  33. Genetic architecture of subcortical brain structures in 38,851 individuals

    Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., Van Der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., Den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C-Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., De Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., Van Eijk, K. R., Cavalleri, G. L., Van Der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., Van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B-C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J-J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., Van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., Van Tol, M-J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., Van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J-L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., Van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., Van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., Destefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., Van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., Decarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., 30 Nov 2019, In: Nature Genetics. 51, 11, p. 1624–1636 13 p.

    Research output: Contribution to journalArticlepeer-review

  34. Limited One-time Sampling Irregularity Map (LOTS-IM) for Automatic Unsupervised Assessment of White Matter Hyperintensities and Multiple Sclerosis Lesions in Structural Brain Magnetic Resonance Images

    Rachmadi, M. F., Del C. Valdés-hernández, M., Li, H., Guerrero, R., Meijboom, R., Wiseman, S., Waldman, A., Zhang, J., Rueckert, D., Wardlaw, J. & Komura, T., 27 Nov 2019, In: Computerized Medical Imaging and Graphics. 79, 101685.

    Research output: Contribution to journalArticlepeer-review

  35. Preventing foot ulceration in diabetes: systematic review and meta-analyses of RCT data

    Crawford, F., Nicolson, D. J., Amanna, A. E., Martin, A., Gupta, S., Leese, G. P., Heggie, R., Chappell, F. M. & Mcintosh, H. H., 27 Nov 2019, In: Diabetologia. 63, 1, p. 49-64

    Research output: Contribution to journalArticlepeer-review

  36. Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative

    De Guio, F., Duering, M., Fazekas, F., De Leeuw, F., Greenberg, S. M., Pantoni, L., Aghetti, A., Smith, E. E., Wardlaw, J. & Jouvent, E., 20 Nov 2019, In: Journal of Cerebral Blood Flow and Metabolism. p. 0271678X1988896

    Research output: Contribution to journalReview articlepeer-review

  37. Three-Dimensional Shape Modeling and Analysis of Brain Structures

    Kim, J., Valdés Hernández, M. D. C. & Park, J., 14 Nov 2019, In: Journal of Visualized Experiments. 153

    Research output: Contribution to journalArticlepeer-review

  38. Analysis of dynamic texture and spatial spectral descriptors of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease

    Bernal, J., Valdés-hernández, M. D. C., Escudero, J., Viksne, L., Heye, A. K., Armitage, P. A., Makin, S., Touyz, R. M. & Wardlaw, J. M., 13 Nov 2019, In: Magnetic Resonance Imaging.

    Research output: Contribution to journalArticlepeer-review

  39. Profile of and risk factors for poststroke cognitive impairment in diverse ethno-regional groups

    for the Stroke and Cognition (STROKOG) Collaboration, 11 Nov 2019, In: Neurology. p. 10.1212/WNL.0000000000008612

    Research output: Contribution to journalArticlepeer-review

  40. Predictors of Lesion Cavitation After Recent Small Subcortical Stroke

    Gattringer, T., Valdes Hernandez, M., Heye, A., Armitage, P. A., Makin, S., Chappell, F., Pinter, D., Doubal, F., Enzinger, C., Fazekas, F. & Wardlaw, J. M., 8 Nov 2019, In: Translational Stroke Research.

    Research output: Contribution to journalArticlepeer-review

  41. Modelling Direct Brain Cooling for Acute Ischaemic Stroke with the Vascular-Porous Model

    Fulford, L., Marshall, I., Andrews, P. & Valluri, P., Nov 2019.

    Research output: Contribution to conferenceAbstractpeer-review

  42. Inspiring New Researchers in Stroke: The ESO Edinburgh Stroke Research Workshop

    Orav, K., Moullaali, T. J., Sandset, E. C., Doubal, F. & Whiteley, W., 15 Oct 2019, In: Stroke.

    Research output: Contribution to journalComment/debatepeer-review

  43. Predicting the Evolution of White Matter Hyperintensities in Brain MRI using Generative Adversarial Networks and Irregularity Map

    Rachmadi, M., Valdes Hernandez, M., Makin, S., Wardlaw, J. & Komura, T., 10 Oct 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. Shen, D., Liu, T., Peters, T. M., Staib, L. H., Essert, C., Zhou, S., Yap, P-T. & Khan, A. (eds.). Springer, p. 146–154 9 p. (Lecture Notes in Computer Science (LNCS); vol. 11766).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  44. Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage: Data From the RIGHT-2 Trial

    Bath, P. M., Woodhouse, L. J., Krishnan, K., Appleton, J. P., Anderson, C. S., Berge, E., Cala, L., Dixon, M., England, T. J., Godolphin, P. J., Hepburn, T., Mair, G., Montgomery, A. A., Phillips, S. J., Potter, J., Price, C. I., Randall, M., Robinson, T. G., Roffe, C., Rothwell, P. M. & 7 others, Sandset, E. C., Sanossian, N., Saver, J. L., Siriwardena, A. N., Venables, G., Wardlaw, J. M. & Sprigg, N., 7 Oct 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  45. Mechanical thrombectomy in patients with acute ischemic stroke: A cost-effectiveness and value of implementation analysis

    Heggie, R., Wu, O., White, P., Ford, G. A., Wardlaw, J., Brown, M. M., Clifton, A. & Muir, K. W., 30 Sep 2019, In: International Journal of Stroke. p. 174749301987965

    Research output: Contribution to journalArticlepeer-review

  46. Observer Agreement on Computed Tomography Perfusion Imaging in Acute Ischemic Stroke

    El-tawil, S., Mair, G., Huang, X., Sakka, E., Palmer, J., Ford, I., Kalra, L., Wardlaw, J. & Muir, K. W., 25 Sep 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  47. Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto

    Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B., Rowe, B. & 6 others, Joanette, Y., Hacke, W., Kuller, L., Dichgans, M., Endres, M. & Khachaturian, Z. S., 22 Sep 2019, In: International Journal of Stroke. p. 174749301987191

    Research output: Contribution to journalArticlepeer-review

  48. Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial

    Van Der Worp, H. B., Macleod, M. R., Bath, P. M., Bathula, R., Christensen, H., Colam, B., Cordonnier, C., Demotes-mainard, J., Durand-zaleski, I., Gluud, C., Jakobsen, J. C., Kallmünzer, B., Kollmar, R., Krieger, D. W., Lees, K. R., Michalski, D., Molina, C., Montaner, J., Roine, R. O., Petersson, J. & 8 others, Perry, R., Sprigg, N., Staykov, D., Szabo, I., Vanhooren, G., Wardlaw, J. M., Winkel, P. & Schwab, S., 1 Sep 2019, In: European Stroke Journal. 4, 3, p. 254-262

    Research output: Contribution to journalArticlepeer-review

  49. Brain peak width of skeletonised mean diffusivity (PSMD) and cognitive function in later life

    Deary, I., Ritchie, S. J., Muñoz Maniega, S., Cox, S., Valdes Hernandez, M., Luciano, M., Starr, J., Wardlaw, J. & Bastin, M., 26 Jul 2019, In: Frontiers in psychiatry. 10, 524.

    Research output: Contribution to journalArticlepeer-review

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