Edinburgh Research Explorer

Small Vessel Disease Research

Organisational unit: Research Group

  1. 2019
  2. Associations between vascular risk factors and brain MRI indices in UK Biobank

    Cox, S. R., Lyall, D. M., Ritchie, S. J., Bastin, M. E., Harris, M. A., Buchanan, C. R., Fawns-Ritchie, C., Barbu, M., de Nooij, L., Reus, L. M., Alloza, C., Shen, X., Neilson, E., Alderson, H. L., Hunter, S., Liewald, D. C., Whalley, H. C., McIntosh, A. M., Lawrie, S. M., Pell, J. P. & 4 others, Tucker-Drob, E. M., Wardlaw, J. M., Gale, C. R. & Deary, I. J., 21 Jul 2019, In: European Heart Journal. 40, 28, p. 2290–2300 11 p.

    Research output: Contribution to journalArticlepeer-review

  3. Preventing dementia by preventing stroke: The Berlin Manifesto

    Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B., Rowe, B. & 6 others, Joanette, Y., Hacke, W., Kuller, L., Dichgans, M., Endres, M. & Khachaturian, Z. S., 18 Jul 2019, In: Alzheimer's & Dementia. 15, 7, p. 961-984

    Research output: Contribution to journalArticlepeer-review

  4. Lowering blood pressure after acute intracerebral haemorrhage: protocol for a systematic review and meta-analysis using individual patient data from randomised controlled trials participating in the Blood Pressure in Acute Stroke Collaboration (BASC)

    Moullaali, T. J., Wang, X., Woodhouse, L. J., Law, Z. K., Delcourt, C., Sprigg, N., Krishnan, K., Robinson, T. G., Wardlaw, J. M., Al-shahi Salman, R., Berge, E., Sandset, E. C., Anderson, C. S. & Bath, P. M., 16 Jul 2019, In: BMJ Open. 9, 7, e030121.

    Research output: Contribution to journalArticlepeer-review

  5. Structural neuroimaging differentiates vulnerability from disease manifestation in colombian families with Huntington’s disease

    C. Valdés Hernández, M., Abu‐hussain, J., Qiu, X., Priller, J., Parra Rodríguez, M., Pino, M., Báez, S. & Ibáñez, A., 5 Jul 2019, In: Brain and Behavior.

    Research output: Contribution to journalArticlepeer-review

  6. Effects of Isosorbide Mononitrate and/or Cilostazol on Hematological Markers, Platelet Function, and Hemodynamics in Patients With Lacunar Ischaemic Stroke: Safety Data From the Lacunar Intervention-1 (LACI-1) Trial

    Appleton, J. P., Blair, G. W., Flaherty, K., Law, Z. K., May, J., Woodhouse, L. J., Doubal, F., Sprigg, N., Bath, P. M. & Wardlaw, J. M., 3 Jul 2019, In: Frontiers in Neurology. 10

    Research output: Contribution to journalArticlepeer-review

  7. Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

    Wilson, D., Ambler, G., Lee, K-J., Lim, J-S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sánchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K. & 61 others, Wong, A., Kim, Y. D., Song, T-J., Schrooten, M., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Assayag, E. B., Hallevi, H., Tanaka, J., Hara, H., Coutts, S. B., Hert, L., Polymeris, A., Seiffge, D. J., Lyrer, P., Algra, A., Kappelle, J., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Mattle, H. P., Panos, L. D., Mas, J-L., Legrand, L., Karayiannis, C., Phan, T., Gunkel, S., Christ, N., Abrigo, J., Leung, T., Chu, W., Chappell, F., Makin, S., Hayden, D., Williams, D. J., Kooi, M. E., Kvan Dam-Nolen, D. H., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Maaijwee, N., Guevarra, C., Yatawara, C., Mendyk, A-M., Delmaire, C., Köhler, S., van Oostenbrugge, R., Zhou, Y., Xu, C., Hilal, S., Wardlaw, J. M., Jung, S., Sakka, E., Perry, R., Mitchell, J. & Microbleeds International Collaborative Network, 1 Jul 2019, In: Lancet Neurology. 18, 7, p. 653-665 13 p.

    Research output: Contribution to journalArticlepeer-review

  8. Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: Subgroup analyses of the RESTART randomised, open-label trial

    Al-Shahi Salman, R., Minks, D. P., Mitra, D., Rodrigues, M. A., Bhatnagar, P., du Plessis, J. C., Joshi, Y., Dennis, M. S., Murray, G. D., Newby, D. E., Sandercock, P. A. G., Sprigg, N., Stephen, J., Sudlow, C. L. M., Werring, D. J., Whiteley, W. N., Wardlaw, J. M., White, P. M. & RESTART collaboration, 1 Jul 2019, In: Lancet Neurology. 18, 7, p. 643-652 10 p.

    Research output: Contribution to journalArticlepeer-review

  9. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

    Wardlaw, J. & RESTART collaboration, 29 Jun 2019, In: The Lancet. 393, 10191, p. 2613-2623 11 p.

    Research output: Contribution to journalArticlepeer-review

  10. Reaction time variability and brain white matter integrity

    Booth, T., Dykiert, D., Corley, J., Gow, A., Morrison, Z., Munoz-Maniega, S., Royle, N., Valdes Hernandez, M., Starr, J., Penke, L., Bastin, M., Wardlaw, J. & Deary, I., 28 Jun 2019, In: Neuropsychology. 33, 5, p. 642-657

    Research output: Contribution to journalArticlepeer-review

  11. Dilated Saliency U-Net for White Matter Hyperintensities Segmentation Using Irregularity Age Map

    Jeong, Y., Rachmadi, M. F., Valdés-Hernández, M. D. C. & Komura, T., 27 Jun 2019, In: Frontiers in Aging Neuroscience. 11

    Research output: Contribution to journalArticlepeer-review

  12. Perivascular spaces in the centrum semiovale at the beginning of the 8th decade of life: Effect on cognition and associations with mineral deposition

    Valdes Hernandez, M., Ballerini, L., Glatz, A., Munoz-Maniega, S., Gow, A., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., 27 Jun 2019, In: Brain imaging and behavior.

    Research output: Contribution to journalArticlepeer-review

  13. Factors associated with potentially serious incidental findings and with serious final diagnoses on multi-modal imaging in the UK Biobank Imaging Study: a prospective cohort study

    Sudlow, C., Gibson, L., Nolan, J., Littlejohns, T. J., Mathieu, E., Garratt, S., Doherty, N., Petersen, S. E., Harvey, N. C. W., Sellors, J., Allen, N. E., Wardlaw, J. & Jackson, C., 17 Jun 2019, In: PLoS ONE. 16, 6, e0218267.

    Research output: Contribution to journalArticlepeer-review

  14. Evaluation of Enhanced Learning Techniques for Segmenting Ischaemic Stroke Lesions in Brain Magnetic Resonance Perfusion Images Using a Convolutional Neural Network Scheme

    Pérez Malla, C. U., Valdés Hernández, M. D. C., Rachmadi, M. F. & Komura, T., 29 May 2019, In: Frontiers in Neuroinformatics. 13, 33.

    Research output: Contribution to journalArticlepeer-review

  15. Stability of estimated premorbid cognitive ability over time after minor stroke and its relationship with post-stroke cognitive ability

    McHutchison, C. A., Chappell, F. M., Makin, S., Shuler, K., Wardlaw, J. M. & Cvoro, V., 22 May 2019, In: Brain Sciences. 9, 5, p. 1-15 117.

    Research output: Contribution to journalArticlepeer-review

  16. Cortical thickness, white matter hyperintensities, and cognition after stroke

    Dickie, D. A., Gardner, K., Wagener, A., Wyss, A., Arba, F., Wardlaw, J. M. & Dawson, J., 14 May 2019, In: International Journal of Stroke. p. 174749301985129

    Research output: Contribution to journalArticlepeer-review

  17. Small vessel disease: mechanisms and clinical implications

    Wardlaw, J., Smith, C. & Dichgans, M., 13 May 2019, In: Lancet Neurology.

    Research output: Contribution to journalReview articlepeer-review

  18. Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial

    Blair, G. W., Appleton, J. P., Flaherty, K., Doubal, F., Sprigg, N., Dooley, R., Richardson, C., Hamilton, I., Law, Z. K., Shi, Y., Stringer, M. S., Thrippleton, M. J., Boyd, J., Shuler, K., Bath, P. M. & Wardlaw, J. M., 1 May 2019, In: EClinicalMedicine. 11, p. 34-43 10 p.

    Research output: Contribution to journalArticlepeer-review

  19. Hierarchical Complexity of the Adult Human Structural Connectome

    Smith, K., Bastin, M., Cox, S., Valdes Hernandez, M., Wiseman, S., Escudero, J. & Sudlow, C., May 2019, In: NeuroImage. 191, p. 205-215

    Research output: Contribution to journalArticlepeer-review

  20. Quantifying BBB leakage in small vessel disease: review and consensus recommendations

    Thrippleton, M., Backes, W. H., Sourbron, S., Ingrisch, M., van Osch, M. J. P., Dichgans, M., Fazekas, F., Ropele, S., Frayne, R., van Oostenbrugge, R. J., Smith, E. E. & Wardlaw, J., 25 Apr 2019, In: Alzheimer's & Dementia.

    Research output: Contribution to journalArticlepeer-review

  21. Are morphologic features of recent small subcortical infarcts related to specific etiologic aspects?

    Eppinger, S., Gattringer, T., Nachbaur, L., Fandler, S., Pirpamer, L., Ropele, S., Wardlaw, J., Enzinger, C. & Fazekas, F., 22 Apr 2019, In: Therapeutic Advances in Neurological Disorders.

    Research output: Contribution to journalArticlepeer-review

  22. Retinal microvasculature and cerebral small vessel disease in the Lothian Birth Cohort 1936 and Mild Stroke Study

    McGrory, S., Ballerini, L., Doubal, F. N., Staals, J., Allerhand, M., Valdes Hernandez, M. D. C., Wang, X., MacGillivray, T., Doney, A. S. F., Dhillon, B., Starr, J. M., Bastin, M. E., Trucco, E., Deary, I. J. & Wardlaw, J. M., 19 Apr 2019, In: Scientific Reports. 9, 11 p., 6320.

    Research output: Contribution to journalArticlepeer-review

  23. The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: design and multicenter pilot study

    Weaver, N., Zhao, L., Biesbroek, J. M., Kuijf, H. J., Aben, H. P., Bae, H-J., Caballero, M. Á. A., Chappell, F., Chen, C. P. L. H., Dichgans, M., Duering, M., Georgakis, M. K., van der Giessen, R. S., Gyanwalij, B., Hamilton, O., Hilalj, S., vom Hofe, E. M., De Kort, P. L. M., Koudstaal, P. J., Lam, B. Y. K. & 12 others, Lim, J-S., Makin, S., Mok, V. C. T., Shi, L., Valdes Hernandez, M., Venketasubramanian, N., Wardlaw, J., Wollenweber, F. A., Wong, A., Xue, X., Meta VCI Map Consortium & Biessels, G. J., 12 Apr 2019, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticlepeer-review

  24. Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke

    McHutchison, C. A., Cvoro, V., Makin, S., Chappell, F. M., Shuler, K. & Wardlaw, J. M., 9 Apr 2019, In: Journal of Neurology, Neurosurgery & Psychiatry. 90, 4, p. 436-443 8 p.

    Research output: Contribution to journalArticlepeer-review

  25. Combining Neurovascular and Neurodegenerative Magnetic Resonance Imaging Measures in Stroke

    Wyss, A., Dawson, J., Arba, F., Wardlaw, J. M., Dickie, D. A., Diener, H. C., Algra, A., Davis, S., Hankey, G., Lees, K. R., Ovbiagele, B. & Weir, C., 8 Apr 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  26. Percutaneous Vascular Interventions Versus Intravenous Thrombolytic Treatment for Acute Ischemic Stroke

    Lindekleiv, H., Bruins Slot, K. M. H., Wardlaw, J. M. & Berge, E., 2 Apr 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  27. Clinical diagnosis of TIA or minor stroke and prognosis in patients with neurological symptoms: A rapid access clinic cohort

    Sudlow, C., Graham, C., Bailey, D., Hart, S., Hutchison, A., Sandercock, P., Doubal, F., Farrall, A., Wardlaw, J., Dennis, M. & Whiteley, W., 19 Mar 2019, In: PLoS ONE. 14, 3, e0210452.

    Research output: Contribution to journalArticlepeer-review

  28. It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis

    Appleton, J. P., Woodhouse, L. J., Belcher, A., Bereczki, D., Berge, E., Caso, V., Chang, H. M., Christensen, H. K., Collins, R., Gommans, J., Laska, A. C., Ntaios, G., Ozturk, S., Sare, G. M., Szatmari, S., Wang, Y., Wardlaw, J. M., Sprigg, N. & Bath, P. M., 19 Mar 2019, In: Stroke and Vascular Neurology. 4, 1, p. 28-35

    Research output: Contribution to journalArticlepeer-review

  29. WMH and long-term outcomes in ischemic stroke: A systematic review and meta-analysis

    Georgakis, M. K., Duering, M., Wardlaw, J. M. & Dichigans, M., 19 Mar 2019, In: Neurology. 92, 12, p. e1298-e1308 11 p.

    Research output: Contribution to journalArticlepeer-review

  30. Identification of the presence of ischaemic stroke lesions by means of texture analysis on brain magnetic resonance images

    Ortiz-ramón, R., Valdés Hernández, M. D. C., González-castro, V., Makin, S., Armitage, P. A., Aribisala, B. S., Bastin, M. E., Deary, I. J., Wardlaw, J. M. & Moratal, D., 16 Mar 2019, In: Computerized Medical Imaging and Graphics. 74, p. 12-24

    Research output: Contribution to journalArticlepeer-review

  31. Association between Striatal Brain Iron Deposition, Microbleeds and Cognition 1 Year After a Minor Ischaemic Stroke

    Valdés Hernández, M., Case, T., Chappell, F., Glatz, A., Makin, S., Doubal, F. & Wardlaw, J., 14 Mar 2019, In: International Journal of Molecular Sciences. 20, 6, p. 1293

    Research output: Contribution to journalArticlepeer-review

  32. Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): An ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

    The RIGHT-2 Investigators, 9 Mar 2019, In: The Lancet. 393, 10175, p. 1009-1020 12 p.

    Research output: Contribution to journalArticlepeer-review

  33. A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

    Fetit, A. E., Doney, A. S., Hogg, S., Wang, R., Macgillivray, T., Wardlaw, J. M., Doubal, F. N., Mckay, G. J., Mckenna, S. & Trucco, E., 5 Mar 2019, In: Scientific Reports. 9, 1, p. 3591

    Research output: Contribution to journalArticlepeer-review

  34. Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): An international randomised, open-label, blinded-endpoint phase 3 trial

    Anderson, C. S., Huang, Y., Lindley, R. I., Chen, X., Arima, H., Chen, G., Li, Q., Billot, L., Delcourt, C., Bath, P. M., Broderick, J. P., Demchuk, A. M., Donnan, G. A., Durham, A. C., Lavados, P. M., Lee, T. H., Levi, C., Martins, SO., Olavarria, V. V., Pandian, J. D. & 15 others, Parsons, M. W., Pontes-Neto, O. M., Ricci, S., Sato, S., Sharma, V. K., Silva, F., Song, L., Thang, NH., Wardlaw, J. M., Wang, J-G., Wang, X., Woodward, M., Chalmers, J., Robinson, T. G. & ENCHANTED Investigators and Coordinators, 2 Mar 2019, In: The Lancet. 393, 10174, p. 877-888 12 p.

    Research output: Contribution to journalArticlepeer-review

  35. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration

    Smith, E. E., Biessels, G. J., De Guio, F., De Leeuw, F. E., Duchesne, S., Düring, M., Frayne, R., Ikram, M. A., Jouvent, E., Macintosh, B. J., Thrippleton, M. J., Vernooij, M. W., Adams, H., Backes, W. H., Ballerini, L., Black, S. E., Chen, C., Corriveau, R., Decarli, C., Greenberg, S. M. & 29 others, Gurol, M. E., Ingrisch, M., Job, D., Lam, B. Y. K., Launer, L. J., Linn, J., Mccreary, C. R., Mok, V. C. T., Pantoni, L., Pike, G. B., Ramirez, J., Reijmer, Y. D., Romero, J. R., Ropele, S., Rost, N. S., Sachdev, P. S., Scott, C. J. M., Seshadri, S., Sharma, M., Sourbron, S., Steketee, R. M. E., Swartz, R. H., Van Oostenbrugge, R., Van Osch, M., Van Rooden, S., Viswanathan, A., Werring, D., Dichgans, M. & Wardlaw, J. M., 26 Feb 2019, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 191-204

    Research output: Contribution to journalArticlepeer-review

  36. VAMPIRE® fundus image analysis algorithms: Validation and diagnostic relevance in hypertensive cats

    Cirla, A., Drigo, M., Ballerini, L., Trucco, E. & Barsotti, G., 22 Feb 2019, In: Veterinary ophthalmology. p. 1-9

    Research output: Contribution to journalArticlepeer-review

  37. Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: A systematic review and meta-analysis

    Firdaus Francis, F., Ballerini, L. & Wardlaw, J., 14 Feb 2019, In: International Journal of Stroke.

    Research output: Contribution to journalReview articlepeer-review

  38. MRI Relaxometry for Quantitative Analysis of USPIO Uptake in Cerebral Small Vessel Disease

    Thrippleton, M., Blair, G., Valdes-hernandez, M., Glatz, A., Semple, S., Doubal, F., Vesey, A., Marshall, I., Newby, D. & Wardlaw, J., 12 Feb 2019, In: International Journal of Molecular Sciences. 20, 3, p. 776

    Research output: Contribution to journalArticlepeer-review

  39. Manually-parcellated gyral data accounting for all known anatomical variability

    Mikhael, S., Mair, G., Valdes Hernandez, M., Hoogendoorn, C., Wardlaw, J., Bastin, M. & Pernet, C. R., 29 Jan 2019, In: Scientific Data. 6, 12 p., 190001.

    Research output: Contribution to journalArticlepeer-review

  40. Brain morphometry and longitudinal relaxation time of spontaneously hypertensive rats (SHR) in early and intermediate stages of hypertension investigated by 3D VFA-SPGR MRI

    Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, M., Benveniste, H. & Lee, H., 26 Jan 2019, In: Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  41. Effect of Glyceryl Trinitrate on Hemodynamics in Acute Stroke: Data From the ENOS Trial

    ENOS Investigators, 10 Jan 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  42. Convolutional Neural Networks for Direct Inference of Pharmacokinetic Parameters: Application to Stroke Dynamic Contrast-Enhanced MRI

    Ulas, C., Das, D., Thrippleton, M. J., Valdés Hernández, M. D. C., Armitage, P. A., Makin, S. D., Wardlaw, J. M. & Menze, B. H., 8 Jan 2019, In: Frontiers in Neurology. 9

    Research output: Contribution to journalArticlepeer-review

  43. Vascular contributions to cognitive impairment and dementia: Research consortia that focus on etiology and treatable targets to lessen the burden of dementia worldwide

    Gladman, J. T., Corriveau, R. A., Debette, S., Dichgans, M., Greenberg, S. M., Sachdev, P. S., Wardlaw, J. M. & Biessels, G. J., 1 Jan 2019, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, C, p. 789-796

    Research output: Contribution to journalArticlepeer-review

  44. Stroke research in 2018: extended time windows, refined benefit, and lifestyle prevention targets

    Wardlaw, J. M. & Bath, P. M., Jan 2019, In: Lancet Neurology. 18, 1, p. 2-3

    Research output: Contribution to journalComment/debate

  45. Vascular dysfunction – the disregarded partner of Alzheimer’s disease

    Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, Markus, H. S., Salman, R. A., Allan, S. M., Quinn, T. J., Kalaria, R. N., Werring, D. J., Carare, R. O., Touyz, R. M., Williams, S. C. R., Moskowitz, M. A., Katusic, Z. S., Lutz, S. E., Lazarov, O., Minshall, R. D., Rehman, J., Davis, T. P., Wellington, C. L., González, H. M., Yuan, C., Lockhart, S. N., Hughes, T. M., Chen, C. L. H., Sachdev, P., O'Brien, J. T., Skoog, I., Pantoni, L., Gustafson, D. R., Biessels, G. J., Wallin, A., Smith, E. E., Mok, V., Wong, A., Passmore, P., Barkof, F., Muller, M., Breteler, M. M. B., Román, G. C., Hamel, E., Seshadri, S., Gottesman, R. F., van Buchem, M. A., Arvanitakis, Z., Schneider, J. A., Drewes, L. R., Hachinski, V., Finch, C. E., Toga, A. W., Wardlaw, J. M. & Zlokovic, B. V., Jan 2019, In: Alzheimer's & Dementia. 15, 1, p. 158-167 10 p.

    Research output: Contribution to journalComment/debatepeer-review

  46. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

    Chauhan, G., Adams, H. H. H., Satizabal, C. L., Bis, J. C., Teumer, A., Sargurupremraj, M., Hofer, E., Trompet, S., Hilal, S., Smith, A. V., Jian, X., Malik, R., Traylor, M., Pulit, S. L., Amouyel, P., Mazoyer, B., Zhu, Y., Kaffashian, S., Schilling, S., Beecham, G. W. & 130 others, Montine, T. J., Schellenberg, G. D., Kjartansson, O., Guðnason, V., Knopman, D. S., Griswold, M. E., Windham, B. G., Gottesman, R. F., Mosley, T. H., Schmidt, R., Saba, Y., Schmidt, H., Takeuchi, F., Yamaguchi, S., Nabika, T., Kato, N., Rajan, K. B., Aggarwal, N. T., De Jager, P. L., Evans, D. A., Psaty, B. M., Rotter, J. I., Rice, K., Lopez, O. L., Liao, J., Chen, C., Cheng, C., Wong, T. Y., Ikram, M. K., Van Der Lee, S. J., Amin, N., Chouraki, V., Destefano, A. L., Aparicio, H. J., Romero, J. R., Maillard, P., Decarli, C., Wardlaw, J. M., Hernández, M. D. C. V., Luciano, M., Liewald, D., Deary, I. J., Starr, J. M., Bastin, M. E., Muñoz Maniega, S., Slagboom, P. E., Beekman, M., Deelen, J., Uh, H., Lemmens, R., Brodaty, H., Wright, M. J., Ames, D., Boncoraglio, G. B., Hopewell, J. C., Beecham, A. H., Blanton, S. H., Wright, C. B., Sacco, R. L., Wen, W., Thalamuthu, A., Armstrong, N. J., Chong, E., Schofield, P. R., Kwok, J. B., Van Der Grond, J., Stott, D. J., Ford, I., Jukema, J. W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Van Der Lugt, A., Wittfeld, K., Grabe, H. J., Hosten, N., Von Sarnowski, B., Völker, U., Levi, C., Jimenez-conde, J., Sharma, P., Sudlow, C. L. M., Rosand, J., Woo, D., Cole, J. W., Meschia, J. F., Slowik, A., Thijs, V., Lindgren, A., Melander, O., Grewal, R. P., Rundek, T., Rexrode, K., Rothwell, P. M., Arnett, D. K., Jern, C., Johnson, J. A., Benavente, O. R., Wasssertheil-smoller, S., Lee, J., Wong, Q., Mitchell, B. D., Rich, S. S., Mcardle, P. F., Geerlings, M. I., Van Der Graaf, Y., De Bakker, P. I. W., Asselbergs, F. W., Srikanth, V., Thomson, R., Mcwhirter, R., Moran, C., Callisaya, M., Phan, T., Rutten-jacobs, L. C. A., Bevan, S., Tzourio, C., Mather, K. A., Sachdev, P. S., Van Duijn, C. M., Worrall, B. B., Dichgans, M., Kittner, S. J., Markus, H. S., Ikram, M. A., Fornage, M., Launer, L. J., Seshadri, S., Longstreth, W. T. & Debette, S., 2019, In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  47. 2018
  48. Polygenic risk score for schizophrenia and structural brain connectivity in older age: A longitudinal connectome and tractography study

    Alloza, C., Cox, S. R., Blesa Cábez, M., Redmond, P., Whalley, H. C., Ritchie, S. J., Muñoz Maniega, S., del C Valdés Hernández, M., Tucker-Drob, E. M., Lawrie, S. M., Wardlaw, J. M., Deary, I. J. & Bastin, M. E., 31 Dec 2018, In: NeuroImage. 183, p. 884-896 13 p.

    Research output: Contribution to journalArticlepeer-review

  49. Childhood neurodevelopment after prescription of maintenance methadone for opioid dependency in pregnancy: a systematic review and meta-analysis

    Monnelly, V. J., Hamilton, R., Chappell, F. M., Mactier, H. & Boardman, J. P., 3 Dec 2018, In: Developmental medicine and child neurology.

    Research output: Contribution to journalReview articlepeer-review

  50. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

    Franceschini, N., Giambartolomei, C., De Vries, P. S., Finan, C., Bis, J. C., Huntley, R. P., Lovering, R. C., Tajuddin, S. M., Winkler, T. W., Graff, M., Kavousi, M., Dale, C., Smith, A. V., Hofer, E., Van Leeuwen, E. M., Nolte, I. M., Lu, L., Scholz, M., Sargurupremraj, M., Pitkänen, N. & 137 others, Franzén, O., Joshi, P. K., Noordam, R., Marioni, R. E., Hwang, S., Musani, S. K., Schminke, U., Palmas, W., Isaacs, A., Correa, A., Zonderman, A. B., Hofman, A., Teumer, A., Cox, A. J., Uitterlinden, A. G., Wong, A., Smit, A. J., Newman, A. B., Britton, A., Ruusalepp, A., Sennblad, B., Hedblad, B., Pasaniuc, B., Penninx, B. W., Langefeld, C. D., Wassel, C. L., Tzourio, C., Fava, C., Baldassarre, D., O’leary, D. H., Teupser, D., Kuh, D., Tremoli, E., Mannarino, E., Grossi, E., Boerwinkle, E., Schadt, E. E., Ingelsson, E., Veglia, F., Rivadeneira, F., Beutner, F., Chauhan, G., Heiss, G., Snieder, H., Campbell, H., Völzke, H., Markus, H. S., Deary, I. J., Jukema, J. W., De Graaf, J., Price, J., Pott, J., Hopewell, J. C., Liang, J., Thiery, J., Engmann, J., Gertow, K., Rice, K., Taylor, K. D., Dhana, K., Kiemeney, L. A. L. M., Lind, L., Raffield, L. M., Launer, L. J., Holdt, L. M., Dörr, M., Dichgans, M., Traylor, M., Sitzer, M., Kumari, M., Kivimaki, M., Nalls, M. A., Melander, O., Raitakari, O., Franco, O. H., Rueda-ochoa, O. L., Roussos, P., Whincup, P. H., Amouyel, P., Giral, P., Anugu, P., Wong, Q., Malik, R., Rauramaa, R., Burkhardt, R., Hardy, R., Schmidt, R., De Mutsert, R., Morris, R. W., Strawbridge, R. J., Wannamethee, S. G., Hägg, S., Shah, S., Mclachlan, S., Trompet, S., Seshadri, S., Kurl, S., Heckbert, S. R., Ring, S., Harris, T. B., Lehtimäki, T., Galesloot, T. E., Shah, T., De Faire, U., Plagnol, V., Rosamond, W. D., Post, W., Zhu, X., Zhang, X., Guo, X., Saba, Y., Dehghan, A., Seldenrijk, A., Morrison, A. C., Hamsten, A., Psaty, B. M., Van Duijn, C. M., Lawlor, D. A., Mook-kanamori, D. O., Bowden, D. W., Schmidt, H., Wilson, J. G., Rotter, J. I., Wardlaw, J. M., Deanfield, J., Halcox, J., Lyytikäinen, L., Loeffler, M., Evans, M. K., Debette, S., Humphries, S. E., Völker, U., Gudnason, V., Hingorani, A. D., Björkegren, J. L. M., Casas, J. P. & O’donnell, C. J., 3 Dec 2018, In: Nature Communications. 9, 1, 5141.

    Research output: Contribution to journalArticlepeer-review

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