Edinburgh Research Explorer

Small Vessel Disease Research

Organisational unit: Research Group

  1. 2018
  2. Visual rating scales of white matter hyperintensities and atrophy: comparison of computed tomography and magnetic resonance imaging

    Ferguson, K., Cvoro, V., Maclullich, A., Shenkin, S., Sandercock, P., Sakka, E. & Wardlaw, J., 23 Mar 2018, In: Journal of Stroke and Cerebrovascular Diseases.

    Research output: Contribution to journalArticlepeer-review

  3. Long-term morphological changes of symptomatic lacunar infarcts and surrounding white matter on structural MRI

    Loos, C. M. J., Makin, S., Staals, J., Dennis, M., van Oostenbrugge, R. J. & Wardlaw, J., 22 Mar 2018, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  4. The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage with cerebral amyloid angiopathy: model development and diagnostic test accuracy study

    Rodrigues, M. A., Samarasekera, N., Lerpiniere, C., Humphreys, C., McCarron, M. O., White, P. M., Nicoll, J. A. R., Sudlow, C. L. M., Cordonnier, C., Wardlaw, J., Smith, C. & Salman, R. A-S., 1 Mar 2018, In: Lancet Neurology. 17, 3, p. 232-240 9 p.

    Research output: Contribution to journalArticlepeer-review

  5. Cognitive abilities, brain white matter hyperintensity volume and structural network connectivity in older age

    Wiseman, S. J., Booth, T., Ritchie, S. J., Cox, S. R., Muñoz Maniega, S., Valdes Hernandez, M. D. C., Dickie, D. A., Royle, N. A., Starr, J. M., Deary, I. J., Wardlaw, J. M. & Bastin, M. E., 28 Feb 2018, In: Human Brain Mapping. 39, 2, p. 622-632 11 p.

    Research output: Contribution to journalArticlepeer-review

  6. Segmentation of White Matter Hyperintensities using Convolutional Neural Networks with Global Spatial Information in Routine Clinical Brain MRI with None or Mild Vascular Pathology

    Rachmadi, M., Valdes Hernandez, M., Agan, M. L. F., Di Perri, C., Komura, T. & Alzheimer's Disease Neuroimaging Initiative, 17 Feb 2018, In: Computerized Medical Imaging and Graphics.

    Research output: Contribution to journalArticlepeer-review

  7. Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): A questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS)

    Navrady, L., Wolters, M., MacIntyre, D., Clarke, T-K., Campbell, A., Murray, A., Evans, K., Seckl, J., Haley, C., Milburn, K., Wardlaw, J., Porteous, D., Deary, I. & McIntosh, A., 1 Feb 2018, In: International Journal of Epidemiology. 47, 1, p. 13-14g

    Research output: Contribution to journalArticlepeer-review

  8. Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering

    Ballerini, L., Lovreglio, R., Valdes Hernandez, M., Ramirez, J., MacIntosh, B., Black, S. & Wardlaw, J., 1 Feb 2018, In: Scientific Reports. 8, 2132.

    Research output: Contribution to journalArticlepeer-review

  9. Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’

    Scutt, P., Appleton, J. P., Dixon, M. S., Woodhouse, L. J., Sprigg, N., Wardlaw, J. M., Montgomery, A. A., Pocock, S. J. & Bath, P. M., 1 Feb 2018, In: European Stroke Journal. p. 239698731875669

    Research output: Contribution to journalArticlepeer-review

  10. Brain structural differences between 73- and 92-year olds matched for childhood intelligence, social background, and intracranial volume

    Ritchie, S. J., Dickie, D. A., Cox, S., Valdes Hernandez, M., Sibbett, R., Pattie, A., Anblagan, D., Redmond, P., Royle, N., Corley, J., Muñoz Maniega, S., Taylor, A., Karama, S., Booth, T., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Feb 2018, In: Neurobiology of Aging. 62, p. 146-158

    Research output: Contribution to journalArticlepeer-review

  11. Brain cortical characteristics of lifetime cognitive ageing

    Cox, S. R., Bastin, M. E., Ritchie, S. J., Dickie, D. A., Liewald, D. C., Muñoz Maniega, S., Redmond, P., Royle, N. A., Pattie, A., Valdes Hernandez, M., Corley, J., Aribisala, B. S., McIntosh, A. M., Wardlaw, J. M. & Deary, I. J., 31 Jan 2018, In: Brain Structure and Function. 223, 1, p. 509–518 10 p.

    Research output: Contribution to journalArticlepeer-review

  12. Predictors of gait speed and its change over three years in community-dwelling older people

    Pinter, D., Ritchie, S. J., Gattringer, T., Bastin, M., Valdes Hernandez, M., Corley, J., Muñoz Maniega, S., Pattie, A., Dickie, D. A., Gow, A., Starr, J., Deary, I., Enzinger, C., Fazekas, F. & Wardlaw, J., 20 Jan 2018, In: Aging.

    Research output: Contribution to journalArticlepeer-review

  13. The impact of early life intelligence quotient on post stroke cognitive impairment

    Makin, S., Doubal, F., Shuler, K., Chappell, F., Staals, J., Dennis, M. & Wardlaw, J., 8 Jan 2018, In: European Stroke Journal.

    Research output: Contribution to journalArticlepeer-review

  14. Coupled changes in hippocampal structure and cognitive ability in later life

    Anblagan, D., Valdes Hernandez, M., Ritchie, S. J., Aribisala, B., Royle, N., Hamilton, I., Cox, S., Gow, A., Pattie, A., Corley, J., Starr, J., Muñoz Maniega, S., Bastin, M., Deary, I. & Wardlaw, J., 4 Jan 2018, In: Brain and Behavior.

    Research output: Contribution to journalArticlepeer-review

  15. White matter hyperintensity and stroke lesion segmentation and differentiation using convolutional neural networks

    Guerrero, R., Qin, C., Oktay, O., Bowles, C., Chen, L., Joules, R., Wolz, R., Valdes-Hernandez, M. C., Dickie, D. A., Wardlaw, J. & Rueckert, D., 2018, In: NeuroImage: Clinical. 17, p. 918-934 16 p.

    Research output: Contribution to journalArticlepeer-review

  16. 2017
  17. Variance components associated with long-echo-time MR spectroscopic imaging in human brain at 1.5T and 3T

    Thrippleton, M., Parikh, J., Semple, S., Harris, B., Andrews, P., Wardlaw, J. & Marshall, I., 29 Dec 2017, In: PLoS ONE.

    Research output: Contribution to journalArticlepeer-review

  18. Reference Tracts and Generative Models for Brain White Matter Tractography †

    Muñoz Maniega, S., Bastin, M., Deary, I., Wardlaw, J. & Clayden, J., 28 Dec 2017, In: Journal of Imaging . 4, 1, p. 8

    Research output: Contribution to journalArticlepeer-review

  19. Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data

    Campbell, B. C. V., Van Zwam, W. H., Goyal, M., Menon, B. K., Dippel, D. W. J., Demchuk, A. M., Bracard, S., White, P., Dávalos, A., Majoie, C. B. L. M., Van Der Lugt, A., Ford, G. A., De La Ossa, N. P., Kelly, M., Bourcier, R., Donnan, G. A., Roos, Y. B. W. E. M., Bang, O. Y., Nogueira, R. G., Devlin, T. G. & 1,356 others, Van Den Berg, L. A., Clarençon, F., Burns, P., Carpenter, J., Berkhemer, O. A., Yavagal, D. R., Pereira, V. M., Ducrocq, X., Dixit, A., Quesada, H., Epstein, J., Davis, S. M., Jansen, O., Rubiera, M., Urra, X., Micard, E., Lingsma, H. F., Naggara, O., Brown, S., Guillemin, F., Muir, K. W., Van Oostenbrugge, R. J., Saver, J. L., Jovin, T. G., Hill, M. D., Mitchell, P. J., Berkhemer, O. A., Fransen, P. S., Beumer, D., Van Den Berg, L. A., Lingsma, H. F., Yoo, A. J., Schonewille, W. J., Vos, J. A., Nederkoorn, P. J., Wermer, M. J., Van Walderveen, M. A., Staals, J., Hofmeijer, J., Van Oostayen, J. A., Lycklama À Nijeholt, G. J., Boiten, J., Brouwer, P. A., Emmer, B. J., De Bruijn, S. F., Van Dijk, L. C., Kappelle, J., Lo, R. H., Van Dijk, E. J., De Vries, J., De Kort, P. L. M., Van Rooij, W. J. J., Van Den Berg, J. S. P., Van Hasselt, B. A. A. M., Aerden, L. A. M., Dallinga, R. J., Visser, M. C., Bot, J. C. J., Vroomen, P. C., Eshghi, O., Schreuder, T. H. C. M. L., Heijboer, R. J. J., Keizer, K., Tielbeek, A. V., Den Hertog, H. M., Gerrits, D. G., Van Den Berg-vos, R. M., Karas, G. B., Steyerberg, E. W., Flach, Z., Marquering, H. A., Sprengers, M. E. S., Jenniskens, S. F. M., Beenen, L. F. M., Van Den Berg, R., Koudstaal, P. J., Van Zwam, W. H., Roos, Y. B. W. E. M., Van Der Lugt, A., Van Oostenbrugge, R. J., Majoie, C. B. L. M., Dippel, D. W. J., Brown, M. M., Liebig, T., Stijnen, T., Andersson, T., Mattle, H., Wahlgren, N., Van Der Heijden, E., Ghannouti, N., Fleitour, N., Hooijenga, I., Puppels, C., Pellikaan, W., Geerling, A., Lindl-velema, A., Van Vemde, G., De Ridder, A., Greebe, P., De Bont-stikkelbroeck, J., De Meris, J., Janssen, K., Struijk, W., Licher, S., Boodt, N., Ros, A., Venema, E., Slokkers, I., Ganpat, R., Mulder, M., Saiedie, N., Heshmatollah, A., Schipperen, S., Vinken, S., Van Boxtel, T., Koets, J., Boers, M., Santos, E., Borst, J., Jansen, I., Kappelhof, M., Lucas, M., Geuskens, R., Barros, R. S., Dobbe, R., Csizmadia, M., Hill, M., Goyal, M., Demchuk, A., Menon, B., Eesa, M., Ryckborst, K., Wright, M., Kamal, N., Andersen, L., Randhawa, P., Stewart, T., Patil, S., Minhas, P., Almekhlafi, M., Mishra, S., Clement, F., Sajobi, T., Shuaib, A., Montanera, W., Roy, D., Silver, F., Jovin, T., Frei, D., Sapkota, B., Rempel, J., Thornton, J., Williams, D., Tampieri, D., Poppe, A., Dowlatshahi, D., Wong, J., Mitha, A., Subramaniam, S., Hull, G., Lowerison, M., Sajobi, T., Salluzzi, M., Wright, M., Maxwell, M., Lacusta, S., Drupals, E., Armitage, K., Barber, P., Smith, E., Morrish, W., Coutts, S., Derdeyn, C., Demaerschalk, B., Yavagal, D., Martin, R., Brant, R., Yu, Y., Willinsky, R., Montanera, W., Weill, A., Kenney, C., Aram, H., Stewart, T., Stys, P., Watson, T., Klein, G., Pearson, D., Couillard, P., Trivedi, A., Singh, D., Klourfeld, E., Imoukhuede, O., Nikneshan, D., Blayney, S., Reddy, R., Choi, P., Horton, M., Musuka, T., Dubuc, V., Field, T., Desai, J., Adatia, S., Alseraya, A., Nambiar, V., Van Dijk, R., Wong, J., Mitha, A., Morrish, W., Eesa, M., Newcommon, N., Shuaib, A., Schwindt, B., Butcher, K., Jeerakathil, T., Buck, B., Khan, K., Naik, S., Emery, D., Owen, R., Kotylak, T., Ashforth, R., Yeo, T., Mcnally, D., Siddiqui, M., Saqqur, M., Hussain, D., Kalashyan, H., Manosalva, A., Kate, M., Gioia, L., Hasan, S., Mohammad, A., Muratoglu, M., Williams, D., Thornton, J., Cullen, A., Brennan, P., O'hare, A., Looby, S., Hyland, D., Duff, S., Mccusker, M., Hallinan, B., Lee, S., Mccormack, J., Moore, A., O'connor, M., Donegan, C., Brewer, L., Martin, A., Murphy, S., O'rourke, K., Smyth, S., Kelly, P., Lynch, T., Daly, T., O'brien, P., O'driscoll, A., Martin, M., Daly, T., Collins, R., Coughlan, T., Mccabe, D., Murphy, S., O'neill, D., Mulroy, M., Lynch, O., Walsh, T., O'donnell, M., Galvin, T., Harbison, J., Mcelwaine, P., Mulpeter, K., Mcloughlin, C., Reardon, M., Harkin, E., Dolan, E., Watts, M., Cunningham, N., Fallon, C., Gallagher, S., Cotter, P., Crowe, M., Doyle, R., Noone, I., Lapierre, M., Coté, V., Lanthier, S., Odier, C., Durocher, A., Raymond, J., Weill, A., Daneault, N., Deschaintre, Y., Jankowitz, B., Baxendell, L., Massaro, L., Jackson-graves, C., Decesare, S., Porter, P., Armbruster, K., Adams, A., Billigan, J., Oakley, J., Ducruet, A., Jadhav, A., Giurgiutiu, D., Aghaebrahim, A., Reddy, V., Hammer, M., Starr, M., Totoraitis, V., Wechsler, L., Streib, S., Rangaraju, S., Campbell, D., Rocha, M., Gulati, D., Silver, F., Krings, T., Kalman, L., Cayley, A., Williams, J., Stewart, T., Wiegner, R., Casaubon, L., Jaigobin, C., Del Campo, J., Elamin, E., Schaafsma, J., Willinsky, R., Agid, R., Farb, R., Ter Brugge, K., Sapkoda, B., Baxter, B., Barton, K., Knox, A., Porter, A., Sirelkhatim, A., Devlin, T., Dellinger, C., Pitiyanuvath, N., Patterson, J., Nichols, J., Quarfordt, S., Calvert, J., Hawk, H., Fanale, C., Frei, D., Bitner, A., Novak, A., Huddle, D., Bellon, R., Loy, D., Wagner, J., Chang, I., Lampe, E., Spencer, B., Pratt, R., Bartt, R., Shine, S., Dooley, G., Nguyen, T., Whaley, M., Mccarthy, K., Teitelbaum, J., Tampieri, D., Poon, W., Campbell, N., Cortes, M., Dowlatshahi, D., Lum, C., Shamloul, R., Robert, S., Stotts, G., Shamy, M., Steffenhagen, N., Blacquiere, D., Hogan, M., Alhazzaa, M., Basir, G., Lesiuk, H., Iancu, D., Santos, M., Choe, H., Weisman, D., Jonczak, K., Blue-schaller, A., Shah, Q., Mackenzie, L., Klein, B., Kulandaivel, K., Kozak, O., Gzesh, D., Harris, L., Khoury, J., Mandzia, J., Pelz, D., Crann, S., Fleming, L., Hesser, K., Beauchamp, B., Amato-marzialli, B., Boulton, M., Lopez- Ojeda, P., Sharma, M., Lownie, S., Chan, R., Swartz, R., Howard, P., Golob, D., Gladstone, D., Boyle, K., Boulos, M., Hopyan, J., Yang, V., Da Costa, L., Holmstedt, C., Turk, A., Navarro, R., Jauch, E., Ozark, S., Turner, R., Phillips, S., Shankar, J., Jarrett, J., Gubitz, G., Maloney, W., Vandorpe, R., Schmidt, M., Heidenreich, J., Hunter, G., Kelly, M., Whelan, R., Peeling, L., Burns, P., Hunter, A., Wiggam, I., Kerr, E., Watt, M., Fulton, A., Gordon, P., Rennie, I., Flynn, P., Smyth, G., O'leary, S., Gentile, N., Linares, G., Mcnelis, P., Erkmen, K., Katz, P., Azizi, A., Weaver, M., Jungreis, C., Faro, S., Shah, P., Reimer, H., Kalugdan, V., Saposnik, G., Bharatha, A., Li, Y., Kostyrko, P., Santos, M., Marotta, T., Montanera, W., Sarma, D., Selchen, D., Spears, J., Heo, J., Jeong, K., Kim, D., Kim, B., Kim, Y., Song, D., Lee, K., Yoo, J., Bang, O., Rho, S., Lee, J., Jeon, P., Kim, K., Cha, J., Kim, S., Ryoo, S., Lee, M., Sohn, S., Kim, C., Ryu, H., Hong, J., Chang, H., Lee, C., Rha, J., Davis, S. M., Donnan, G. A., Campbell, B. C., Mitchell, P. J., Churilov, L., Yan, B., Dowling, R., Yassi, N., Oxley, T. J., Wu, T. Y., Silver, G., Mcdonald, A., Mccoy, R., Kleinig, T. J., Scroop, R., Dewey, H. M., Simpson, M., Brooks, M., Coulton, B., Krause, M., Harrington, T. J., Steinfort, B., Faulder, K., Priglinger, M., Day, S., Phan, T., Chong, W., Holt, M., Chandra, R. V., Ma, H., Young, D., Wong, K., Wijeratne, T., Tu, H., Mackay, E., Celestino, S., Bladin, C. F., Loh, P. S., Gilligan, A., Ross, Z., Coote, S., Frost, T., Parsons, M. W., Miteff, F., Levi, C. R., Ang, T., Spratt, N., Kaauwai, L., Badve, M., Rice, H., De Villiers, L., Barber, P. A., Mcguinness, B., Hope, A., Moriarty, M., Bennett, P., Wong, A., Coulthard, A., Lee, A., Jannes, J., Field, D., Sharma, G., Salinas, S., Cowley, E., Snow, B., Kolbe, J., Stark, R., King, J., Macdonnell, R., Attia, J., D'este, C., Saver, J. L., Goyal, M., Diener, H. C., Levy, E. I., Bonafé, A., Mendes Pereira, V., Jahan, R., Albers, G. W., Cognard, C., Cohen, D. J., Hacke, W., Jansen, O., Jovin, T. G., Mattle, H. P., Nogueira, R. G., Siddiqui, A. H., Yavagal, D. R., Von Kummer, R., Smith, W., Turjman, F., Hamilton, S., Chiacchierini, R., Amar, A., Sanossian, N., Loh, Y., Devlin, T., Baxter, B., Hawk, H., Sapkota, B., Quarfordt, S., Sirelkhatim, A., Dellinger, C., Barton, K., Reddy, V., Ducruet, A., Jadhav, A., Horev, A., Giurgiutiu, D., Totoraitis, V., Hammer, M., Jankowitz, B., Wechsler, L., Rocha, M., Gulati, D., Campbell, D., Star, M., Baxendell, L., Oakley, J., Siddiqui, A., Hopkins, L., Snyder, K., Sawyer, R., Hall, S., Costalat, V., Riquelme, C., Machi, P., Omer, E., Arquizan, C., Mourand, I., Charif, M., Ayrignac, X., Menjot De Champfleur, N., Leboucq, N., Gascou, G., Moynier, M., Du Mesnil De Rochemont, R., Singer, O., Berkefeld, J., Foerch, C., Lorenz, M., Pfeilschifer, W., Hattingen, E., Wagner, M., You, S., Lescher, S., Braun, H., Dehkharghani, S., Belagaje, S., Anderson, A., Lima, A., Obideen, M., Haussen, D., Dharia, R., Frankel, M., Patel, V., Owada, K., Saad, A., Amerson, L., Horn, C., Doppelheuer, S., Schindler, K., Lopes, D., Chen, M., Moftakhar, R., Anton, C., Smreczak, M., Carpenter, J., Boo, S., Rai, A., Roberts, T., Tarabishy, A., Gutmann, L., Brooks, C., Brick, J., Domico, J., Reimann, G., Hinrichs, K., Becker, M., Heiss, E., Selle, C., Witteler, A., Al'boutros, S., Danch, M., Ranft, A., Rohde, S., Burg, K., Weimar, C., Zegarac, V., Hartmann, C., Schlamann, M., Göricke, S., Ringlestein, A., Wanke, I., Mönninghoff, C., Dietzold, M., Budzik, R., Davis, T., Eubank, G., Hicks, W., Pema, P., Vora, N., Mejilla, J., Taylor, M., Clark, W., Rontal, A., Fields, J., Peterson, B., Nesbit, G., Lutsep, H., Bozorgchami, H., Priest, R., Ologuntoye, O., Barnwell, S., Dogan, A., Herrick, K., Takahasi, C., Beadell, N., Brown, B., Jamieson, S., Hussain, M., Russman, A., Hui, F., Wisco, D., Uchino, K., Khawaja, Z., Katzan, I., Toth, G., Cheng Ching, E., Bain, M., Man, S., Farrag, A., George, P., John, S., Shankar, L., Drofa, A., Dahlgren, R., Bauer, A., Itreat, A., Taqui, A., Cerejo, R., Richmond, A., Ringleb, P., Bendszus, M., Möhlenbruch, M., Reiff, T., Amiri, H., Purrucker, J., Herweh, C., Pham, M., Menn, O., Ludwig, I., Acosta, I., Villar, C., Morgan, W., Sombutmai, C., Hellinger, F., Allen, E., Bellew, M., Gandhi, R., Bonwit, E., Aly, J., Ecker, R., Seder, D., Morris, J., Skaletsky, M., Belden, J., Baker, C., Connolly, L., Papanagiotou, P., Roth, C., Kastrup, A., Politi, M., Brunner, F., Alexandrou, M., Merdivan, H., Ramsey, C., Given Ii, C., Renfrow, S., Deshmukh, V., Sasadeusz, K., Vincent, F., Thiesing, J., Putnam, J., Bhatt, A., Kansara, A., Caceves, D., Lowenkopf, T., Yanase, L., Zurasky, J., Dancer, S., Freeman, B., Scheibe Mirek, T., Robison, J., Rontal, A., Roll, J., Clark, D., Rodriguez, M., Fitzsimmons, B., Zaidat, O., Lynch, J., Lazzaro, M., Larson, T., Padmore, L., Das, E., Farrow Schmidt, A., Hassan, A., Tekle, W., Cate, C., Jansen, O., Cnyrim, C., Wodarg, F., Wiese, C., Binder, A., Riedel, C., Rohr, A., Lang, N., Laufs, H., Krieter, S., Remonda, L., Diepers, M., Añon, J., Nedeltchev, K., Kahles, T., Biethahn, S., Lindner, M., Chang, V., Gächter, C., Esperon, C., Guglielmetti, M., Arenillas Lara, J., Martínez Galdámez, M., Calleja Sanz, A., Cortijo Garcia, E., Garcia Bermejo, P., Perez, S., Mulero Carrillo, P., Crespo Vallejo, E., Ruiz Piñero, M., Lopez Mesonero, L., Reyes Muñoz, F., Brekenfeld, C., Buhk, J., Kruützelmann, A., Thomalla, G., Cheng, B., Beck, C., Hoppe, J., Goebell, E., Holst, B., Grzyska, U., Wortmann, G., Starkman, S., Duckwiler, G., Jahan, R., Rao, N., Sheth, S., Ng, K., Noorian, A., Szeder, V., Nour, M., Mcmanus, M., Huang, J., Tarpley, J., Tateshima, S., Gonzalez, N., Ali, L., Liebeskind, D., Hinman, J., Calderon Arnulphi, M., Liang, C., Guzy, J., Koch, S., Desousa, K., Gordon Perue, G., Haussen, D., Elhammady, M., Peterson, E., Pandey, V., Dharmadhikari, S., Khandelwal, P., Malik, A., Pafford, R., Gonzalez, P., Ramdas, K., Andersen, G., Damgaard, D., Von Weitzel Mudersbach, P., Simonsen, C., Ruiz De Morales Ayudarte, N., Poulsen, M., Sørensen, L., Karabegovich, S., Hjørringgaard, M., Hjort, N., Harbo, T., Sørensen, K., Deshaies, E., Padalino, D., Swarnkar, A., Latorre, J., Elnour, E., El Zammar, Z., Villwock, M., Farid, H., Balgude, A., Cross, L., Hansen, K., Holtmannspötter, M., Kondziella, D., Hoejgaard, J., Taudorf, S., Soendergaard, H., Wagner, A., Cronquist, M., Stavngaard, T., Cortsen, M., Krarup, L., Hyldal, T., Haring, H., Guggenberger, S., Hamberger, M., Trenkler, J., Sonnberger, M., Nussbaumer, K., Dominger, C., Bach, E., Jagadeesan, B., Taylor, R., Kim, J., Shea, K., Tummala, R., Zacharatos, H., Sandhu, D., Ezzeddine, M., Grande, A., Hildebrandt, D., Miller, K., Scherber, J., Hendrickson, A., Jumaa, M., Zaidi, S., Hendrickson, T., Snyder, V., Killer Oberpfalzer, M., Mutzenbach, J., Weymayr, F., Broussalis, E., Stadler, K., Jedlitschka, A., Malek, A., Mueller Kronast, N., Beck, P., Martin, C., Summers, D., Day, J., Bettinger, I., Holloway, W., Olds, K., Arkin, S., Akhtar, N., Boutwell, C., Crandall, S., Schwartzman, M., Weinstein, C., Brion, B., Prothmann, S., Kleine, J., Kreiser, K., Boeckh Behrens, T., Poppert, H., Wunderlich, S., Koch, M., Biberacher, V., Huberle, A., Gora Stahlberg, G., Knier, B., Meindl, T., Utpadel Fischler, D., Zech, M., Kowarik, M., Seifert, C., Schwaiger, B., Puri, A., Hou, S., Wakhloo, A., Moonis, M., Henniger, N., Goddeau, R., Massari, F., Minaeian, A., Lozano, J., Ramzan, M., Stout, C., Patel, A., Tunguturi, A., Onteddu, S., Carandang, R., Howk, M., Ribó, M., Sanjuan, E., Rubiera, M., Pagola, J., Flores, A., Muchada, M., Meler, P., Huerga, E., Gelabert, S., Coscojuela, P., Tomasello, A., Rodriguez, D., Santamarina, E., Maisterra, O., Boned, S., Seró, L., Rovira, A., Molina, C., Millán, M., Muñoz, L., Pérez De La Ossa, N., Gomis, M., Dorado, L., López-cancio, E., Palomeras, E., Munuera, J., García Bermejo, P., Remollo, S., Castaño, C., García-sort, R., Cuadras, P., Puyalto, P., Hernández-pérez, M., Jiménez, M., Martínez-piñeiro, A., Lucente, G., Dávalos, A., Chamorro, A., Urra, X., Obach, V., Cervera, A., Amaro, S., Llull, L., Codas, J., Balasa, M., Navarro, J., Ariño, H., Aceituno, A., Rudilosso, S., Renu, A., Macho, J., San Roman, L., Blasco, J., López, A., Macías, N., Cardona, P., Quesada, H., Rubio, F., Cano, L., Lara, B., De Miquel, M., Aja, L., Serena, J., Cobo, E., Albers, G. W., Lees, K. R., Arenillas, J., Roberts, R., Minhas, P., Al-ajlan, F., Salluzzi, M., Zimmel, L., Patel, S., Eesa, M., Martí-fàbregas, J., Jankowitz, B., Serena, J., Salvat-plana, M., López-cancio, E., Bracard, S., Ducrocq, X., Anxionnat, R., Baillot, P., Barbier, C., Derelle, A., Lacour, J., Richard, S., Samson, Y., Sourour, N., Baronnet-chauvet, F., Clarencon, F., Crozier, S., Deltour, S., Di Maria, F., Le Bouc, R., Leger, A., Mutlu, G., Rosso, C., Szatmary, Z., Yger, M., Zavanone, C., Bakchine, S., Pierot, L., Caucheteux, N., Estrade, L., Kadziolka, K., Leautaud, A., Renkes, C., Serre, I., Desal, H., Guillon, B., Boutoleau-bretonniere, C., Daumas-duport, B., De Gaalon, S., Derkinderen, P., Evain, S., Herisson, F., Laplaud, D., Lebouvier, T., Lintia-gaultier, A., Pouclet-courtemanche, H., Rouaud, T., Rouaud Jaffrenou, V., Schunck, A., Sevin-allouet, M., Toulgoat, F., Wiertlewski, S., Gauvrit, J., Ronziere, T., Cahagne, V., Ferre, J., Pinel, J., Raoult, H., Mas, J., Meder, J., Al Najjar-carpentier, A., Birchenall, J., Bodiguel, E., Calvet, D., Domigo, V., Godon-hardy, S., Guiraud, V., Lamy, C., Majhadi, L., Morin, L., Naggara, O., Trystram, D., Turc, G., Berge, J., Sibon, I., Menegon, P., Barreau, X., Rouanet, F., Debruxelles, S., Kazadi, A., Renou, P., Fleury, O., Pasco-papon, A., Dubas, F., Caroff, J., Godard Ducceschi, S., Hamon, M., Lecluse, A., Marc, G., Giroud, M., Ricolfi, F., Bejot, Y., Chavent, A., Gentil, A., Kazemi, A., Osseby, G., Voguet, C., Mahagne, M., Sedat, J., Chau, Y., Suissa, L., Lachaud, S., Houdart, E., Stapf, C., Buffon Porcher, F., Chabriat, H., Guedin, P., Herve, D., Jouvent, E., Mawet, J., Saint-maurice, J., Schneble, H., Turjman, F., Nighoghossian, N., Berhoune, N., Bouhour, F., Cho, T., Derex, L., Felix, S., Gervais-bernard, H., Gory, B., Manera, L., Mechtouff, L., Ritzenthaler, T., Riva, R., Salaris Silvio, F., Tilikete, C., Blanc, R., Obadia, M., Bartolini, M. B., Gueguen, A., Piotin, M., Pistocchi, S., Redjem, H., Drouineau, J., Neau, J., Godeneche, G., Lamy, M., Marsac, E., Velasco, S., Clavelou, P., Chabert, E., Bourgois, N., Cornut-chauvinc, C., Ferrier, A., Gabrillargues, J., Jean, B., Marques, A., Vitello, N., Detante, O., Barbieux, M., Boubagra, K., Favre Wiki, I., Garambois, K., Tahon, F., Ashok, V., Voguet, C., Coskun, O., Guedin, P., Rodesch, G., Lapergue, B., Bourdain, F., Evrard, S., Graveleau, P., Decroix, J. P., Wang, A., Sellal, F., Ahle, G., Carelli, G., Dugay, M., Gaultier, C., Lebedinsky, A. P., Lita, L., Musacchio, R. M., Renglewicz-destuynder, C., Tournade, A., Vuillemet, F., Montoro, F. M., Mounayer, C., Faugeras, F., Gimenez, L., Labach, C., Lautrette, G., Denier, C., Saliou, G., Chassin, O., Dussaule, C., Melki, E., Ozanne, A., Puccinelli, F., Sachet, M., Sarov, M., Bonneville, J., Moulin, T., Biondi, A., De Bustos Medeiros, E., Vuillier, F., Courtheoux, P., Viader, F., Apoil-brissard, M., Bataille, M., Bonnet, A., Cogez, J., Kazemi, A., Touze, E., Leclerc, X., Leys, D., Aggour, M., Aguettaz, P., Bodenant, M., Cordonnier, C., Deplanque, D., Girot, M., Henon, H., Kalsoum, E., Lucas, C., Pruvo, J., Zuniga, P., Bonafé, A., Arquizan, C., Costalat, V., Machi, P., Mourand, I., Riquelme, C., Bounolleau, P., Arteaga, C., Faivre, A., Bintner, M., Tournebize, P., Charlin, C., Darcel, F., Gauthier-lasalarie, P., Jeremenko, M., Mouton, S., Zerlauth, J., Lamy, C., Hervé, D., Hassan, H., Gaston, A., Barral, F., Garnier, P., Beaujeux, R., Wolff, V., Herbreteau, D., Debiais, S., Murray, A., Ford, G., Muir, K. W., White, P., Brown, M. M., Clifton, A., Freeman, J., Ford, I., Markus, H., Wardlaw, J., Lees, K. R., Molyneux, A., Robinson, T., Lewis, S., Norrie, J., Robertson, F., Perry, R., Dixit, A., Cloud, G., Clifton, A., Madigan, J., Roffe, C., Nayak, S., Lobotesis, K., Smith, C., Herwadkar, A., Kandasamy, N., Goddard, T., Bamford, J., Subramanian, G., Lenthall, R., Littleton, E., Lamin, S., Storey, K., Ghatala, R., Banaras, A., Aeron-thomas, J., Hazel, B., Maguire, H., Veraque, E., Harrison, L., Keshvara, R. & Cunningham, J., 16 Dec 2017, In: Lancet Neurology. 17, 1, p. 47-53

    Research output: Contribution to journalArticlepeer-review

  20. Deep Learning vs. Conventional Machine Learning: Pilot Study of WMH Segmentation in Brain MRI with Absence or Mild Vascular Pathology

    Rachmadi, M., Valdes Hernandez, M., Agan, M. L. F., Komura, T. & Alzheimer’s Disease Neuroimaging Initiative, 14 Dec 2017, In: Journal of Imaging .

    Research output: Contribution to journalArticlepeer-review

  21. Intracranial pulsatility in patients with cerebral small vessel disease: a systematic review

    Shi, Y., Thrippleton, M., Marshall, I. & Wardlaw, J., 11 Dec 2017, In: Clinical science.

    Research output: Contribution to journalArticlepeer-review

  22. Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials

    Hacke, W., Lyden, P., Emberson, J., Baigent, C., Blackwell, L., Albers, G. W., Bluhmki, E., Brott, T. G., Cohen, G. R., Davis, S. M., Donnan, G. A., Grotta, J. C., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Olivot, J. M., Parsons, M. & 8 others, Sandercock, P., Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., Whiteley, W., del Zoppo, G. J. & Lees, K. R., 24 Nov 2017, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  23. Relationship between race and outcome in Asian, Black, and Caucasian patients with spontaneous intracerebral hemorrhage: Data from the Virtual International Stroke Trials Archive and Efficacy of Nitric Oxide in Stroke trial

    Krishnan, K., Beishon, L., Berge, E., Christensen, H., Dineen, R. A., Ozturk, S., Sprigg, N., Wardlaw, J. M. & Bath, P. M., 22 Nov 2017, In: International Journal of Stroke. p. 174749301774446

    Research output: Contribution to journalArticlepeer-review

  24. Dietary iodine exposure and brain structures and cognition in older people. Exploratory analysis in the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Kyle, J., Allan, J., Allerhand, M., Clark, H., Muñoz Maniega, S., Royle, N., Gow, A., Pattie, A., Corley, J., Bastin, M., Starr, J., Wardlaw, J., Deary, I. & Combet, E., Nov 2017, In: The Journal of Nutrition, Health & Aging. 21, 9, p. 971-979

    Research output: Contribution to journalArticlepeer-review

  25. Risk and protective factors for structural brain ageing in the eighth decade of life

    Ritchie, S. J., Tucker-Drob, E. M., Cox, S., Dickie, D. A., Valdes Hernandez, M., Corley, J., Royle, N., Redmond, P., Muñoz Maniega, S., Pattie, A., Aribisala, B., Taylor, A., Clarke, T-K., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Nov 2017, In: Brain Structure and Function. 222, 8, p. 1-14 14 p.

    Research output: Contribution to journalArticlepeer-review

  26. Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability

    ENIGMA Consortium, 20 Oct 2017, In: Nature Communications.

    Research output: Contribution to journalArticlepeer-review

  27. Optimizing the Definitions of Stroke, TIA and Infarction for Research and Application in Clinical Practice

    Abbott, A. L., Silvestrini, M., Topakian, R., Golledge, J., Brunser, A., de Borst, G. J., Harbaugh, R. E., Doubal, F., Rundek, T., Thapar, A., Davies, A. H., Kam, A. & Wardlaw, J., 18 Oct 2017, In: Frontiers in Neurology.

    Research output: Contribution to journalArticlepeer-review

  28. Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis

    Duncombe, J., Lennen, R. J., Jansen, M. A., Marshall, I., Wardlaw, J. M. & Horsburgh, K., Oct 2017, In: Neuropathology and Applied Neurobiology. 43, 6

    Research output: Contribution to journalArticlepeer-review

  29. Processing speed and the relationship between Trail Making Test-B performance, cortical thinning and white matter microstructure in older adults

    MacPherson, S. E., Cox, S. R., Dickie, D. A., Karama, S., Starr, J. M., Evans, A. C., Bastin, M. E., Wardlaw, J. M. & Deary, I. J., Oct 2017, In: Cortex. 95, p. 92-103

    Research output: Contribution to journalArticlepeer-review

  30. Cerebrovascular reactivity measurement in cerebral small vessel disease: rationale and reproducibility of a protocol for MRI acquisition and image processing

    Thrippleton, M., Shi, Y., Blair, G., Hamilton, I., Waiter, G. D., Schwarzbauer, C., Pernet, C. R., Andrews, P., Marshall, I., Doubal, F. & Wardlaw, J., 21 Sep 2017, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  31. Retinal Biomarker Discovery for Dementia in an Elderly Diabetic Population

    VAMPIRE project, Vascular Assessment and Measurement Platform for Images of the REtina, 9 Sep 2017, International Workshop on Ophthalmic Medical Image Analysis. Springer, p. 150-158 (LNCS; vol. 10554).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  32. Small vessel disease and dietary salt intake: cross sectional study and systematic review

    Makin, S., Mubki, G. F., Doubal, F., Shuler, K., Staals, J., Dennis, M. & Wardlaw, J., 8 Sep 2017, In: Journal of Stroke and Cerebrovascular Diseases.

    Research output: Contribution to journalArticlepeer-review

  33. Blood pressure variability and leukoaraiosis in acute ischemic stroke

    Dickie, D. A., Aribisala, B., Mair, G., Berge, E., Lindley, R. I., Sandercock, P., von Kummer, R., von Heijne, A., Peeters, A., Cala, L., Farrall, A., Morris, Z., Bradey, N., Potter, G., Adami, A. & Wardlaw, J., 5 Sep 2017, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  34. White matter hyperintensity reduction and outcomes after minor stroke

    Wardlaw, J. M., Chappell, F. M., Valdés Hernández, M. D. C., Makin, S. D. J., Staals, J., Shuler, K., Thrippleton, M. J., Armitage, P. A., Muñoz Maniega, S., Heye, A. K., Sakka, E. & Dennis, M. S., 5 Sep 2017, In: Neurology. 89, 10, p. 1003-1010

    Research output: Contribution to journalArticlepeer-review

  35. Maximising the Potential of Longitudinal Cohorts for Research in Neurodegenerative Diseases: A Community Perspective

    Moody, C., Mitchell, D., Kiser, G., Aarsland, D., Berg, D., Brayne, C., Costa, A., Arfan Ikram, M., Mountain, G., Rohrer, J. D., Teunissen, C., van den Berg, L. H. & Wardlaw, J., 29 Aug 2017, In: Frontiers in Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  36. Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)

    Appleton, J. P., Scutt, P., Dixon, M., Howard, H., Haywood, L., Havard, D., Hepburn, T., England, T., Sprigg, N., Woodhouse, L. J., Wardlaw, J. M., Montgomery, A. A., Pocock, S., Bath, P. M. & RIGHT-2 Investigators, 1 Aug 2017, In: International Journal of Stroke. p. 1747493017724627

    Research output: Contribution to journalArticlepeer-review

  37. Brain grey and white matter predictors of verbal ability traits in older age: The Lothian Birth Cohort 1936

    Hoffman, P., Cox, S. R., Dykiert, D., Muñoz Maniega, S., Valdes Hernandez, M. C., Bastin, M. E., Wardlaw, J. M. & Deary, I. J., 1 Aug 2017, In: NeuroImage. 156, p. 394-402 9 p.

    Research output: Contribution to journalArticlepeer-review

  38. Infections up to 76 days after stroke increase disability and death

    Learoyd, A. E., Woodhouse, L., Shaw, L., Sprigg, N., Bereczki, D., Berge, E., Caso, V., Christensen, H., Collins, R., Czlonkowska, A., El Etribi, A., Farr, T. D., Gommans, J., Laska, A. C., Ntaios, G., Ozturk, S., Pocock, S. J., Prasad, K., Wardlaw, J., Fone, K. & 2 others, Bath, P. M. & Trueman, R. C., 27 Jul 2017, In: Translational Stroke Research.

    Research output: Contribution to journalArticlepeer-review

  39. Application of texture analysis to study small vessel disease and blood brain barrier integrity

    Valdes Hernandez, M., Gonzalez- Castro, V., Chappell, F., Sakka, E., Makin, S., Armitage, P., Nailon, W. H. & Wardlaw, J., 19 Jul 2017, In: Frontiers in Neurology. 8, p. 327 1 p.

    Research output: Contribution to journalArticlepeer-review

  40. Detection, risk factors, and functional consequences of cerebral microinfarcts

    van Veluw, S. J., Shih, A. Y., Smith, E. E., Chen, C., Schneider, J. A., Wardlaw, J., Greenberg, S. M. & Biessels, G. J., 14 Jul 2017, In: Lancet Neurology.

    Research output: Contribution to journalArticlepeer-review

  41. Education, socioeconomic status, and intelligence in childhood and stroke risk in later life: A Meta-analysis

    McHutchison, C., Backhouse, E., Cvoro, V., Shenkin, S. & Wardlaw, J., Jul 2017, In: Epidemiology. 28, 4

    Research output: Contribution to journalArticlepeer-review

  42. Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 Study

    McGrory, S., Taylor, A., Kirin, M., Corley, J., Pattie, A., Cox, S., Dhillon, B., Wardlaw, J., Doubal, F., Starr, J., Trucco, E., MacGillivray, T. & Deary, I., Jul 2017, In: British Journal of Ophthalmology. 101, 7, p. 993-998

    Research output: Contribution to journalArticlepeer-review

  43. Small vessel disease and clinical outcomes after IV rt-PA treatment

    Arba, F., Inzitari, D., Ali, M., Warach, S. J., Luby, M., Lees, K. R., Albers, G. W., Davis, S. M., Donnan, G. A., Fisher, M., Furlan, A. J., Grotta, J. C., Hacke, W., Kang, D. W., Kidwell, C., Koroshetz, W. J., Lev, M. H., Liebeskind, D. S., Gregory Sorensen, A., Thijs, V. N. & 3 others, Thomalla, G., Wardlaw, J. M. & Wintermark, M., Jul 2017, In: Acta neurologica Scandinavica. 136, 1, p. 72-77 6 p.

    Research output: Contribution to journalArticlepeer-review

  44. Evaluation of Four Supervised Learning Schemes in White Matter Hyperintensities Segmentation in Absence or Mild Presence of Vascular Pathology

    Rachmadi, M., Komura, T., Valdes Hernandez, M. & Agan, M., 22 Jun 2017, Medical Image Understanding and Analysis (MIUA 2017). Springer, Cham, p. 482-493 12 p. (Communications in Computer and Information Science; vol. 723).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  45. Improved reference tracts for unsupervised brain white matter tractography

    Muñoz Maniega, S., Bastin, M., Deary, I., Wardlaw, J. & Clayden, J. D., 22 Jun 2017, Medical Image Understanding and Analysis: 21st Annual Conference, MIUA 2017, Edinburgh, UK, July 11–13, 2017, Proceedings. p. 425-435 (Communications in Computer and Information Science).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  46. Super Resolution Convolutional Neural Networks for Increasing Spatial Resolution of 1H Magnetic Resonance Spectroscopic Imaging

    Cengiz, S., Valdes Hernandez, M. & Ozturk-Isik, E., 22 Jun 2017, Medical Image Understanding and Analysis: 21st Annual Conference, MIUA 2017, Edinburgh, UK, July 11–13, 2017, Proceedings.. p. 641-650 (Communications in Computer and Information Science).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  47. Advanced neuroimaging of cerebral small vessel disease

    Blair, G., Valdes Hernandez, M., Thrippleton, M., Doubal, F. & Wardlaw, J., 15 Jun 2017, In: Current Treatment Options in Cardiovascular Medicine.

    Research output: Contribution to journalArticlepeer-review

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