Edinburgh Research Explorer

Small Vessel Disease Research

Organisational unit: Research Group

  1. 2020
  2. Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta-analysis

    Hamilton, O., Backhouse, E., Janssen, E., Jochems, A., Maher, C., Ritakari, T., Stevenson, A., Xia, L., Deary, I. & Wardlaw, J., 13 Nov 2020, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  3. Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial

    Beishon, L., Woodhouse, L. J., Bereczki, D., Christensen, H. K., Collins, R., Gommans, J., Kruuse, C., Ntaios, G., Ozturk, S., Phillips, S., Pocock, S., Szatmari, S., Wardlaw, J., Sprigg, N. & Bath, P. M., 5 Nov 2020, In : Stroke and Vascular Neurology. p. svn-2020-000498

    Research output: Contribution to journalArticle

  4. The association between CT biomarkers of cerebral small vessel diseases and long‐term outcome after spontaneous intracerebral hemorrhage

    Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators, 3 Nov 2020, In : Annals of Neurology.

    Research output: Contribution to journalArticle

  5. Feasibility and diagnostic accuracy of using brain attenuation changes on CT to estimate time of ischemic stroke onset

    Mair, G., Alzahrani, A., Lindley, R. I., Sandercock, P. A. G. & Wardlaw, J. M., 30 Oct 2020, In : Neuroradiology.

    Research output: Contribution to journalArticle

  6. Intensive versus guideline‐recommended blood pressure reduction in acute lacunar stroke with intravenous thrombolysis therapy: the ENCHANTED trial

    Zhou, Z., Xia, C., Carcel, C., Yoshimura, S., Wang, X., Delcourt, C., Malavera, A., Chen, X., Mair, G., Woodward, M., Chalmers, J., Demchuk, A. M., Lindley, R. I., Robinson, T. G., Parsons, M. W., Wardlaw, J. M. & Anderson, C. S., 17 Oct 2020, In : European Journal of Neurology.

    Research output: Contribution to journalArticle

  7. Brain imaging abnormalities and outcome after acute ischaemic stroke: the ENCHANTED trial

    Delcourt, C., Wang, X., Zhou, Z., Wardlaw, J., Mair, G., Robinson, T., Chen, X., Yoshimura, S., Torii-yoshimura, T., Carcel, C., Calic, Z., Yong Tan, W., Malavera, A., Anderson, C. S. & Lindley, R. I., 14 Oct 2020, In : Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journalArticle

  8. A new dawn of preventing dementia by preventing cerebrovascular diseases

    Pan, Y., Li, H., Wardlaw, J. M. & Wang, Y., 9 Oct 2020, In : British Medical Journal (BMJ). p. m3692

    Research output: Contribution to journalArticle

  9. Predictive Intelligence in Medicine

    Rekik, I., Adeli, E., Park, S. H. P. & Valdes Hernandez, M., 8 Oct 2020

    Research output: Book/ReportBook

  10. The glymphatic system and its role in cerebral homeostasis

    Benveniste, H., Elkin, R., Heerdt, P., Koundal, S., Xue, Y., Lee, H., Wardlaw, J. & Tannenbaum, A., 1 Oct 2020, In : Journal of Applied Physiology.

    Research output: Contribution to journalArticle

  11. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22824 adults

    Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., Zare, H., Ahmad, S., Armstrong, N. J., Satizabal, C. L., Bernard, M., Bis, J. C., Gillespie, N. A., Luciano, M., Mishra, A., Scholz, M., Teumer, A., Xia, R., Jian, X., Mosley, T. H. & 79 others, Saba, Y., Pirpamer, L., Seiler, S., Becker, J. T., Carmichael, O., Rotter, J. I., Psaty, B. M., Lopez, O. L., Amin, N., van der Lee, S. J., Yang, Q., Himali, J. J., Maillard, P., Beiser, A., DeCarli, C., Karama, S., Lewis, L., Harris, M., Bastin, M., Deary, I., Witte, A. V., Beyer, F., Loeffler, M., Mather, K. A., Schofield, P. R., Thalamuthu, A., Kwok, J. B. J., Wright, M. J., Ames, D., Trollor, J. N., Jiang, J., Brodaty, H., Wen, W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Niessen, W. J., Wittfeld, K., Bülow, R., Völker, U., Pausova, Z., Pike, G. B., Maingault, S., Crivello, F., Tzourio, C., Amouyel, P., Mazoyer, B., Neale, M. C., Franz, C. E., Lyons, M. J., Panizzon, M. S., Andreassen, O. A., Dale, A. M., Logue, M. A., Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Stein, J. L., Thompson, P., Medland, S. E., Sachdev, P. S., Kremen, W. S., Wardlaw, J., Villringer, A., van Duijn, C., Grabe, H. J., Longstreth, W. T., Fornage, M., Paus, T., Debette, S., Ikram, M. A., Schmidt, H., Schmidt, R. & Seshadri, S., 22 Sep 2020, In : Nature Communications. 11, 4796 .

    Research output: Contribution to journalArticle

  12. 4D flow MRI for non-invasive measurement of blood flow in the brain: A systematic review

    Morgan, A. G., Thrippleton, M. J., Wardlaw, J. M. & Marshall, I., 16 Sep 2020, In : Journal of Cerebral Blood Flow and Metabolism. p. 0271678X2095201

    Research output: Contribution to journalArticle

  13. A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease

    Stringer, M. S., Lee, H., Huuskonen, M. T., Macintosh, B. J., Brown, R., Montagne, A., Atwi, S., Ramirez, J., Jansen, M. A., Marshall, I., Black, S. E., Zlokovic, B. V., Benveniste, H. & Wardlaw, J. M., 16 Sep 2020, In : Translational Stroke Research.

    Research output: Contribution to journalArticle

  14. Association of common genetic variants with brain microbleeds: A genome-wide association study

    Knol, M. J., Lu, D., Traylor, M., Adams, H. H. H., Rafael Romero, J., Smith, A. V., Fornage, M., Hofer, E., Liu, J., Hostettler, I., Luciano, M., Trompet, S., Giese, A-K., Hilal, S., van den Akker, E., Vojinovic, D., Li, S., Sigurdsson, S., van der Lee, S., Jack, C. R. & 43 others, Wilson, D., Yilmaz, P., Satizabal, C. L., Liewald, D., van der Grond, J., Chen, C., Saba, Y., van der Lugt, A., Bastin, M., Windham, B. G., Cheng, C-Y., Pirpamer, L., Kantarci, K., Himali, J. J., Yang, Q., Morris, Z., Beiser, A., Tozer, D. J., Vernooij, M. W., Amin, N., Beekman, M., Koh, J. Y., Stott, D., Houlden, H., Schmidt, R., Gottesman, R. F., Mackinnon, A., Decarli, C., Gudnason, V., Deary, I., van Duijn, C., Slagboom, P. E., Wong, T. Y., Rost, N., Wouter Jukema, J., Mosley, T. H., Werring, D., Schmidt, H., Wardlaw, J., Ikram, M. A., Seshadri, S., Lenore, L. J. & Markus, H. S., 10 Sep 2020, In : Neurology.

    Research output: Contribution to journalArticle

  15. Cerebral small vessel disease genomics and its implications across the lifespan

    Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S., Rajan, K. B., van den Akker, E., McWhirter, R. E., Trompet, S., Mishra, A. & 97 others, Saba, Y., Satizabal, C. L., Beaudet, G., Petit, L., Tsuchida, A., Zago, L., Schilling, S., Sigurdsson, S., Gottesman, R. F., Lewis, C. E., Aggarwal, N. T., Lopez, O. L., Smith, J. A., Valdes Hernandez, M., van der Grond, J., Wright, M. J., Knol, M. J., Dörr, M., Thomson, R., Bordes, C., Le Grand, Q., Duperron, M-G., Smith, A. V., Knopman, D. S., Schreiner, P. J., Evans, D. A., Rotter, J. I., Beiser, A. S., Muñoz Maniega, S., Beekman, M., Trollor, J. N., Stott, D. J., Vernooij, M. W., Wittfield, K., Niessen, W. J., Soumaré, A., Boerwinkle, E., Sidney, S. S., Turner, S. T., Davies, G., Thalamuthu, A., Völker, U., Van Buchem, M. A., Bryan, R. N., Dupuis, J., Bastin, M., Ames, D., Teumer, A., Amouyel, P., Kwok, J. B. J., Bülow, R., Deary, I., Schofield, P. R., Brodaty, H., Jiang, J., Tabara, Y., Setoh, K., Miyamoto, S., Yoshida, K., Nagata, M., Kamatani, Y., Matsuda, F., Psaty, B. M., Bennett, D. A., De Jager, P. L., Mosley, T. H., Sachdev, P. S., Schmidt, R., Warren, H. R., Evangelou, E., Trégouët, D. A., Ikram, M. A., Wen, W., DeCarli, C., Srikanth, V. K., Wouter Jukema, J., Slagboom, P. E., Kardia, S. L. R., Okada, Y., Mazoyer, B., Wardlaw, J., Nyquist, P. A., Mather, K. A., Grabe, H. J., Schmidt, H., van Duijn, C., Gudnason, V., Longstreth, W. T., Lenore, L. J., Lathrop, G. M., Campbell, A., Seshadri, S., Tzourio, C., Adams, H. H. H., Matthews, P. M., Fornage, M. & Debette, S., 10 Sep 2020, (Accepted/In press) In : Nature Communications.

    Research output: Contribution to journalArticle

  16. Quantitative measurements of enlarged perivascular spaces in the brain are associated with retinal microvascular parameters in older community-dwelling subjects

    Ballerini, L., McGrory, S., Valdes Hernandez, M., Lovreglio, R., Pellegrini, E., MacGillivray, T., Muñoz Maniega, S., Henderson, R., Taylor, A., Bastin, M., Doubal, F., Trucco, E., Deary, I. & Wardlaw, J., 21 Aug 2020, In : Cerebral Circulation—Cognition and Behavior. 1, 100002.

    Research output: Contribution to journalArticle

  17. Diffuse white matter loss in a transgenic rat model of cerebral amyloid angiopathy

    Lee, H., Xu, F., Liu, X., Koundal, S., Zhu, X., Davis, J., Yanez, D., Schrader, J., Stanisavljevic, A., Rothman, D. L., Wardlaw, J., Van Nostrand, W. E. & Benveniste, H., 13 Aug 2020, In : Journal of Cerebral Blood Flow and Metabolism. p. 0271678X2094422

    Research output: Contribution to journalArticle

  18. Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID‐19 pandemic, now and in the future

    Mok, V. C. T., Pendlebury, S., Wong, A., Alladi, S., Au, L., Bath, P. M., Biessels, G. J., Chen, C., Cordonnier, C., Dichgans, M., Dominguez, J., Gorelick, P. B., Kim, S., Kwok, T., Greenberg, S. M., Jia, J., Kalaria, R., Kivipelto, M., Naegandran, K., Lam, L. C. W. & 15 others, Lam, B. Y. K., Lee, A. T. C., Markus, H. S., O'brien, J., Pai, M., Pantoni, L., Sachdev, P., Skoog, I., Smith, E. E., Srikanth, V., Suh, G., Wardlaw, J., Ko, H., Black, S. E. & Scheltens, P., 12 Aug 2020, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  19. Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis

    Mchutchison, C., Blair, G. W., Appleton, J. P., Chappell, F. M., Doubal, F., Bath, P. M. & Wardlaw, J. M., 10 Jul 2020, In : Stroke. 51, 8, p. 2374-2385

    Research output: Contribution to journalArticle

  20. A Framework for Jointly Assessing and Reducing Imaging Artefacts Automatically Using Texture Analysis and Total Variation Optimisation for Improving Perivascular Spaces Quantification in Brain Magnetic Resonance Imaging

    Bernal, J., Valdés-hernández, M., Ballerini, L., Escudero, J., Jochems, A. C. C., Clancy, U., Doubal, F. N., Stringer, M. S., Thrippleton, M. J., Touyz, R. M. & Wardlaw, J. M., 8 Jul 2020, Conference on Medical Image Understanding and Analysis (MIUA) 2020. Springer, Vol. 1248. p. 171-183 Chapter 14. (Medical Image Understanding and Analysis; vol. 1248).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  21. Retinal Biomarkers Discovery for Cerebral Small Vessel Disease in an Older Population

    Ballerini, L., Fetit, A. E., Wunderlich, S., Lovreglio, R., Mcgrory, S., Valdes-hernandez, M., Macgillivray, T., Doubal, F., Deary, I. J., Wardlaw, J. & Trucco, E., 8 Jul 2020, Medical Image Understanding and Analysis. MIUA 2020. Communications in Computer and Information Science. Papież, B., Namburete, A., Yaqub, M. & Noble, J. (eds.). Springer, p. 400-409 Chapter 31. (Medical Image Understanding and Analysis; vol. 1248).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  22. Accuracy of identifying incident stroke cases from linked healthcare data in UK Biobank

    Rannikmae, K., Ngoh, K., Bush, K., Salman, R., Doubal, F., Flaig, R., Henshall, D., Hutchison, A., Nolan, J., Osborne, S., Samarasekera, N., Schnier, C., Whiteley, W., Wilkinson, T., Wilson, K., Zhang, Q., Allen, N. & Sudlow, C., 2 Jul 2020, In : Neurology.

    Research output: Contribution to journalArticle

  23. Automatic Spatial Estimation of White Matter Hyperintensities Evolution in Brain MRI using Disease Evolution Predictor Deep Neural Networks

    Rachmadi, M. F., Valdés-hernández, M. D. C., Makin, S., Wardlaw, J. & Komura, T., 1 Jul 2020, In : Medical image analysis. 63, 101712.

    Research output: Contribution to journalArticle

  24. Thrombolysis Outcomes in Acute Ischemic Stroke by Fluid-Attenuated Inversion Recovery Hyperintense Arteries

    Zhou, Z., Yoshimura, S., Delcourt, C., Lindley, R. I., You, S., Malavera, A., Torii-yoshimura, T., Carcel, C., Wang, X., Chen, X., Parsons, M. W., Demchuk, A. M., Wardlaw, J. M., Mair, G., Robinson, T. G., Chalmers, J., Xu, J. & Anderson, C. S., 17 Jun 2020, In : Stroke. 51, 7, p. 2240-2243

    Research output: Contribution to journalArticle

  25. Aging-sensitive networks within the human structural connectome are implicated in late-life cognitive declines.

    Madole, J. W., Ritchie, S. J., Cox, S., Buchanan, C., Valdes Hernandez, M., Muñoz Maniega, S., Wardlaw, J., Harris, M., Bastin, M., Deary, I. & Tucker-Drob, E. M., 15 Jun 2020, In : Biological Psychiatry.

    Research output: Contribution to journalArticle

  26. Reporting "specific abilities" after major stroke to better describe prognosis

    Visvanathan, A., Whiteley, W., Mead, G., Lawton, J., Doubal, F. N. & Dennis, M., 13 Jun 2020, In : Journal of Stroke and Cerebrovascular Diseases. 29, 8, p. 104993

    Research output: Contribution to journalArticle

  27. Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

    Armstrong, N. J., Mather, K. A., Sargurupremraj, M., Knol, M. J., Malik, R., Satizabal, C. L., Yanek, L. R., Wen, W., Gudnason, V. G., Dueker, N. D., Elliott, L. T., Hofer, E., Bis, J., Jahanshad, N., Li, S., Logue, M. A., Luciano, M., Scholz, M., Smith, A. V., Trompet, S. & 66 others, Vojinovic, D., Xia, R., Alfaro-almagro, F., Ames, D., Amin, N., Amouyel, P., Beiser, A. S., Brodaty, H., Deary, I. J., Fennema-notestine, C., Gampawar, P. G., Gottesman, R., Griffanti, L., Jack, C. R., Jenkinson, M., Jiang, J., Kral, B. G., Kwok, J. B., Lampe, L., C.m. Liewald, D., Maillard, P., Marchini, J., Bastin, M. E., Mazoyer, B., Pirpamer, L., Rafael Romero, J., Roshchupkin, G. V., Schofield, P. R., Schroeter, M. L., Stott, D. J., Thalamuthu, A., Trollor, J., Tzourio, C., Van Der Grond, J., Vernooij, M. W., Witte, V. A., Wright, M. J., Yang, Q., Morris, Z., Siggurdsson, S., Psaty, B., Villringer, A., Schmidt, H., Haberg, A. K., Van Duijn, C. M., Jukema, J. W., Dichgans, M., Sacco, R. L., Wright, C. B., Kremen, W. S., Becker, L. C., Thompson, P. M., Mosley, T. H., Wardlaw, J. M., Ikram, M. A., Adams, H. H. H., Seshadri, S., Sachdev, P. S., Smith, S. M., Launer, L., Longstreth, W., Decarli, C., Schmidt, R., Fornage, M., Debette, S. & Nyquist, P. A., 10 Jun 2020, In : Stroke.

    Research output: Contribution to journalArticle

  28. Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3

    Clancy, U., Garcia, D. J., Stringer, M. S., Thrippleton, M. J., Valdés-hernández, M. C., Wiseman, S., Hamilton, O. K., Chappell, F. M., Brown, R., Blair, G. W., Hewins, W., Sleight, E., Ballerini, L., Bastin, M. E., Maniega, S. M., Macgillivray, T., Hetherington, K., Hamid, C., Arteaga, C., Morgan, A. G. & 7 others, Manning, C., Backhouse, E., Hamilton, I., Job, D., Marshall, I., Doubal, F. N. & Wardlaw, J. M., 5 Jun 2020, In : European Stroke Journal. p. 239698732092961

    Research output: Contribution to journalArticle

  29. Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study

    Beaudet, G., Tsuchida, A., Petit, L., Tzourio, C., Caspers, S., Schreiber, J., Pausova, Z., Patel, Y., Paus, T., Schmidt, R., Pirpamer, L., Sachdev, P. S., Brodaty, H., Kochan, N. A., Trollor, J. N., Wen, W., Armstrong, N. J., Deary, I., Bastin, M., Wardlaw, J. & 6 others, Muñoz Maniega, S., Witte, A. V., Villringer, A., Duering, M., Debette, S. & Mazoyer, B., 4 May 2020, In : Frontiers in psychiatry. 11, 342.

    Research output: Contribution to journalArticle

  30. Protocol: The Lacunar Intervention Trial 2 (LACI-2). A trial of two repurposed licenced drugs to prevent progression of cerebral small vessel disease

    Wardlaw, J., Bath, P. M. W., Doubal, F., Heye, A., Sprigg, N., Woodhouse, L. J., Blair, G., Appleton, J., Cvoro, V., England, T., Hassan, A., John Werring, D. & Montgomery, A., 20 Apr 2020, In : European Stroke Journal. p. 239698732092011

    Research output: Contribution to journalArticle

  31. Improving Clinical Detection of Acute Lacunar Stroke: Analysis From the IST-3

    Arba, F., Mair, G., Phillips, S., Sandercock, P. & Wardlaw, J. M., 9 Apr 2020, In : Stroke.

    Research output: Contribution to journalArticle

  32. Clinical prognosis of FLAIR hyperintense arteries in ischaemic stroke patients: a systematic review and meta-analysis

    Zhou, Z., Malavera, A., Yoshimura, S., Delcourt, C., Mair, G., Al-shahi Salman, R., Demchuk, A. M., Wardlaw, J. M., Lindley, R. I. & Anderson, C. S., 26 Mar 2020, In : Journal of Neurology, Neurosurgery & Psychiatry. p. jnnp-2019-322625

    Research output: Contribution to journalArticle

  33. Global and regional development of the human cerebral cortex: Molecular architecture and occupational aptitudes

    ENIGMA Consortium & neuroCHARGE Cognitive Working group, 20 Mar 2020, In : Cerebral Cortex. bhaa035.

    Research output: Contribution to journalArticle

  34. The genetic architecture of the human cerebral cortex

    Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Ching, C. R. K., Mcmahon, M. A. B., Shatokhina, N., Zsembik, L. C. P., Thomopoulos, S. I., Zhu, A. H., Strike, L. T., Agartz, I., Alhusaini, S., Almeida, M. A. A., Alnæs, D., Amlien, I. K. & 340 others, Andersson, M., Ard, T., Armstrong, N. J., Ashley-koch, A., Atkins, J. R., Bernard, M., Brouwer, R. M., Buimer, E. E. L., Bülow, R., Bürger, C., Cannon, D. M., Chakravarty, M., Chen, Q., Cheung, J. W., Couvy-duchesne, B., Dale, A. M., Dalvie, S., De Araujo, T. K., De Zubicaray, G. I., De Zwarte, S. M. C., Den Braber, A., Doan, N. T., Dohm, K., Ehrlich, S., Engelbrecht, H., Erk, S., Fan, C. C., Fedko, I. O., Foley, S. F., Ford, J. M., Fukunaga, M., Garrett, M. E., Ge, T., Giddaluru, S., Goldman, A. L., Green, M. J., Groenewold, N. A., Grotegerd, D., Gurholt, T. P., Gutman, B. A., Hansell, N. K., Harris, M. A., Harrison, M. B., Haswell, C. C., Hauser, M., Herms, S., Heslenfeld, D. J., Ho, N. F., Hoehn, D., Hoffmann, P., Holleran, L., Hoogman, M., Hottenga, J., Ikeda, M., Janowitz, D., Jansen, I. E., Jia, T., Jockwitz, C., Kanai, R., Karama, S., Kasperaviciute, D., Kaufmann, T., Kelly, S., Kikuchi, M., Klein, M., Knapp, M., Knodt, A. R., Krämer, B., Lam, M., Lancaster, T. M., Lee, P. H., Lett, T. A., Lewis, L. B., Lopes-cendes, I., Luciano, M., Macciardi, F., Marquand, A. F., Mathias, S. R., Melzer, T. R., Milaneschi, Y., Mirza-schreiber, N., Moreira, J. C. V., Mühleisen, T. W., Müller-myhsok, B., Najt, P., Nakahara, S., Nho, K., Olde Loohuis, L. M., Orfanos, D. P., Pearson, J. F., Pitcher, T. L., Pütz, B., Quidé, Y., Ragothaman, A., Rashid, F. M., Reay, W. R., Redlich, R., Reinbold, C. S., Repple, J., Richard, G., Riedel, B. C., Risacher, S. L., Rocha, C. S., Mota, N. R., Salminen, L., Saremi, A., Saykin, A. J., Schlag, F., Schmaal, L., Schofield, P. R., Secolin, R., Shapland, C. Y., Shen, L., Shin, J., Shumskaya, E., Sønderby, I. E., Sprooten, E., Tansey, K. E., Teumer, A., Thalamuthu, A., Tordesillas-gutiérrez, D., Turner, J. A., Uhlmann, A., Vallerga, C. L., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, L., Van Erp, T. G. M., Van Haren, N. E. M., Van Rooij, D., Van Tol, M., Veldink, J. H., Verhoef, E., Walton, E., Wang, M., Wang, Y., Wardlaw, J. M., Wen, W., Westlye, L. T., Whelan, C. D., Witt, S. H., Wittfeld, K., Wolf, C., Wolfers, T., Wu, J. Q., Yasuda, C. L., Zaremba, D., Zhang, Z., Zwiers, M. P., Artiges, E., Assareh, A. A., Ayesa-arriola, R., Belger, A., Brandt, C. L., Brown, G. G., Cichon, S., Curran, J. E., Davies, G. E., Degenhardt, F., Dennis, M. F., Dietsche, B., Djurovic, S., Doherty, C. P., Espiritu, R., Garijo, D., Gil, Y., Gowland, P. A., Green, R. C., Häusler, A. N., Heindel, W., Ho, B., Hoffmann, W. U., Holsboer, F., Homuth, G., Hosten, N., Jack, C. R., Jang, M., Jansen, A., Kimbrel, N. A., Kolskår, K., Koops, S., Krug, A., Lim, K. O., Luykx, J. J., Mathalon, D. H., Mather, K. A., Mattay, V. S., Matthews, S., Mayoral Van Son, J., Mcewen, S. C., Melle, I., Morris, D. W., Mueller, B. A., Nauck, M., Nordvik, J. E., Nöthen, M. M., O’leary, D. S., Opel, N., Martinot, M. P., Pike, G. B., Preda, A., Quinlan, E. B., Rasser, P. E., Ratnakar, V., Reppermund, S., Steen, V. M., Tooney, P. A., Torres, F. R., Veltman, D. J., Voyvodic, J. T., Whelan, R., White, T., Yamamori, H., Adams, H. H. H., Bis, J. C., Debette, S., Decarli, C., Fornage, M., Gudnason, V., Hofer, E., Ikram, M. A., Launer, L., Longstreth, W. T., Lopez, O. L., Mazoyer, B., Mosley, T. H., Roshchupkin, G. V., Satizabal, C. L., Schmidt, R., Seshadri, S., Yang, Q., Alvim, M. K. M., Ames, D., Anderson, T. J., Andreassen, O. A., Arias-vasquez, A., Bastin, M. E., Baune, B. T., Beckham, J. C., Blangero, J., Boomsma, D. I., Brodaty, H., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bustillo, J. R., Cahn, W., Cairns, M. J., Calhoun, V., Carr, V. J., Caseras, X., Caspers, S., Cavalleri, G. L., Cendes, F., Corvin, A., Crespo-facorro, B., Dalrymple-alford, J. C., Dannlowski, U., De Geus, E. J. C., Deary, I. J., Delanty, N., Depondt, C., Desrivières, S., Donohoe, G., Espeseth, T., Fernández, G., Fisher, S. E., Flor, H., Forstner, A. J., Francks, C., Franke, B., Glahn, D. C., Gollub, R. L., Grabe, H. J., Gruber, O., Håberg, A. K., Hariri, A. R., Hartman, C. A., Hashimoto, R., Heinz, A., Henskens, F. A., Hillegers, M. H. J., Hoekstra, P. J., Holmes, A. J., Hong, L. E., Hopkins, W. D., Hulshoff Pol, H. E., Jernigan, T. L., Jönsson, E. G., Kahn, R. S., Kennedy, M. A., Kircher, T. T. J., Kochunov, P., Kwok, J. B. J., Le Hellard, S., Loughland, C. M., Martin, N. G., Martinot, J., Mcdonald, C., Mcmahon, K. L., Meyer-lindenberg, A., Michie, P. T., Morey, R. A., Mowry, B., Nyberg, L., Oosterlaan, J., Ophoff, R. A., Pantelis, C., Paus, T., Pausova, Z., Penninx, B. W. J. H., Polderman, T. J. C., Posthuma, D., Rietschel, M., Roffman, J. L., Rowland, L. M., Sachdev, P. S., Sämann, P. G., Schall, U., Schumann, G., Scott, R. J., Sim, K., Sisodiya, S. M., Smoller, J. W., Sommer, I. E., St Pourcain, B., Stein, D. J., Toga, A. W., Trollor, J. N., Van Der Wee, N. J. A., Van ’t Ent, D., Völzke, H., Walter, H., Weber, B., Weinberger, D. R., Wright, M. J., Zhou, J., Stein, J. L., Thompson, P. M. & Medland, S. E., 20 Mar 2020, In : Science. 367, 6484, eaay6690.

    Research output: Contribution to journalArticle

  35. Opening the floodgates to the brain

    Moss, J. & Williams, A., 13 Mar 2020, Science.

    Research output: Book/ReportCommissioned report

  36. DNA methylation and brain structure and function across the life course: a systematic review

    Wheater, E. N. W., Stoye, D. Q., Cox, S. R., Wardlaw, J. M., Drake, A. J., Bastin, M. E. & Boardman, J. P., 6 Mar 2020, In : Neuroscience and Biobehavioral Reviews.

    Research output: Contribution to journalArticle

  37. Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial

    MS -SMART Investigators, Mar 2020, In : The Lancet Neurology.

    Research output: Contribution to journalArticle

  38. Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND

    McHutchison, C. A., Leighton, D. J., McIntosh, A., Cleary, E., Warner, J., Porteous, M., Chandran, S., Pal, S. & Abrahams, S., Mar 2020, In : Journal of Neurology, Neurosurgery & Psychiatry. 91, 3, p. 245-253

    Research output: Contribution to journalArticle

  39. Polygenic architecture of human neuroanatomical diversity

    Biton, A., Traut, N., Poline, J. B., Aribsala, B., Bastin, M., Bülow, R., Cox, S., Deary, I., Fukunaga, M., Grabe, H. J., Hagenaars, S., Hashimoto, R., Kikuchi, M., Muñoz Maniega, S., Nauck, M., Royle, N., Teumer, A., Valdes Hernandez, M., Völker, U., Wardlaw, J. & 4 others, Wittfield, K., Yamamori, H., Bourgeron, T. & Toro, R., 28 Feb 2020, In : Cerebral Cortex. bhz241.

    Research output: Contribution to journalArticle

  40. Publisher Correction: Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

    Koundal, S., Elkin, R., Nadeem, S., Xue, Y., Constantinou, S., Sanggaard, S., Liu, X., Monte, B., Xu, F., Nostrand, W. V., Nedergaard, M., Lee, H., Wardlaw, J., Benveniste, H. & Tannenbaum, A., 27 Feb 2020, In : Scientific Reports. 10, 1

    Research output: Contribution to journalArticle

  41. Perivascular spaces in the brain: anatomy, physiology and pathology

    Wardlaw, J. M., Benveniste, H., Nedergaard, M., Zlokovic, B. V., Mestre, H., Lee, H., Doubal, F. N., Brown, R., Ramirez, J., Macintosh, B. J., Tannenbaum, A., Ballerini, L., Rungta, R. L., Boido, D., Sweeney, M., Montagne, A., Charpak, S., Joutel, A., Smith, K. J. & Black, S. E., 24 Feb 2020, In : Nature Reviews Neurology.

    Research output: Contribution to journalArticle

  42. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In : Nature Communications. 11, 800.

    Research output: Contribution to journalArticle

  43. Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

    Kounda, S., Elkin, R., Nadeem, S., Xue, Y., Constantinou, S., Sanggaard, S., Liu, X., Monte, B., Xu, F., Van Nostrand, W., Nedergaard, M., Lee, H., Wardlaw, J., Benveniste, H. & Tannenbaum, A., 6 Feb 2020, In : Scientific Reports. 10, 1

    Research output: Contribution to journalArticle

  44. Fluctuating asymmetry in brain structure and general intelligence in 73-Year-olds

    Moodie, J. E., Ritchie, S., Cox, S., Harris, M., Muñoz Maniega, S., Valdes Hernandez, M., Pattie, A., Corley, J., Bastin, M., Starr, J., Wardlaw, J. & Deary, I., 31 Jan 2020, In : Intelligence. 78, 101407.

    Research output: Contribution to journalArticle

  45. Analysis of spatial spectral features of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease

    Bernal Moyano, J., Valdes Hernandez, M., Escudero, J., Armitage, P., Makin, S., Touyz, R. M. & Wardlaw, J., 24 Jan 2020, Medical Image Understanding and Analysis. MIUA 2019. Communications in Computer and Information Science. Springer, Vol. 1065.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  46. Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology

    Varsou, O., Turnbull, K., Stringer, M. S., Fernandes, C. D., Murray, A. D., Schwarzbauer, C. & Macleod, M. J., 23 Jan 2020, In : Neurological Sciences.

    Research output: Contribution to journalArticle

  47. Cerebral small vessel disease: Potential interventions for prevention and treatment

    Blair, G., Appleton, J. P., Wardlaw, J. & Bath, P., 15 Jan 2020, Stroke in the Older Person. Oxford University Press

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  48. Sleep and brain morphological changes in the eighth decade of life

    Aribisala, B. S., Riha, R. L., Valdes Hernandez, M., Maniega, S. M., Cox, S., Radakovic, R., Taylor, A., Pattie, A., Corley, J., Redmond, P., Bastin, M. E., Starr, J., Deary, I. & Wardlaw, J. M., Jan 2020, In : Sleep medicine. 65

    Research output: Contribution to journalArticle

  49. White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed

    Freeze, W. M., Jacobs, H. I. L., De Jong, J. J., Verheggen, I. C. M., Gronenschild, E. H. B. M., Palm, W. M., Hoff, E. I., Wardlaw, J. M., Jansen, J. F. A., Verhey, F. R. & Backes, W. H., Jan 2020, In : Neurobiology of Aging. 85

    Research output: Contribution to journalArticle

  50. 2019
  51. The striatum, the hippocampus, and short-term memory binding: Volumetric analysis of the subcortical grey matter’s role in mild cognitive impairment

    Valdes Hernandez, M., Clark, R., Wang, S-H., Guazzo, F., Calia, C., Pattan, V., Della Sala, S. & Parra, M. A., 29 Dec 2019, In : NeuroImage: Clinical. 25

    Research output: Contribution to journalArticle

  52. Imaging markers of small vessel disease and ‘brain frailty’ and outcomes in acute stroke

    ENOS Investigators, Appleton, J. P., Woodhouse, L., Adami, A., Becker, J. L., Berge, E., Cala, L. A., Casado, A. M., Caso, V., Christensen, H., Dineen, R. A., Gommans, J., Koumellis, P., Szatmari, S., Sprigg, N., Bath, P. M. & Wardlaw, J., 27 Dec 2019, In : Neurology.

    Research output: Contribution to journalArticle

  53. Epigenome-wide meta-analyses of blood DNA methylation and its association with subcortical volumes: Findings from the ENIGMA Epigenetics Working Group

    Jia, T., Chu, C., Liu, Y., van Dongen, J., Papastergios, E., Armstrong, N. J., Bastin, M., Carrillo-roa, T., den Braber, A., Harris, M., Jansen, R., Liu, J., Luciano, M., Ori, A. P. S., Roiz-Santianez, R., Ruggeri, B., Sarkisyan, D., Shin, J., Sungeun, K., Tordesillas-Gutierrez, D. & 62 others, Van't Ent, D., Ames, D., Artiges, E., Bakalkin, G., Banaschewski, T., Bokde, A. L. W., Brodaty, H., Bromberg, U., Brouwer, R. M., Büchel, C., Quinlan, E. B., Cahn, W., de Zubicaray, G. I., Ehrlich, S., Ekström, T. J., Flor, H., Fröhner, J. H., Frouin, V., Garavan, H., Gowland, P. A., Heinz, A., Hoare, J., Ittermann, B., Jahanshad, N., Jiang, J., Kwok, J. B. J., Martin, N. G., Martinot, J-L., Mather, K. A., McMahon, K. L., Mcrae, A. F., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Sämann, P. G., Schofield, P. R., Smolka, M. N., Stein, D. J., Strike, L. T., Teeuw, J., Thalamuthu, A., Trollor, J. N., Walter, H., Wardlaw, J., Wen, W., Whelan, R., Apostolova, L. G., Binder, E. B., Boomsma, D., Calhoun, V. D., Crespo-Facorro, B., Deary, I., Hulshoff Pol, H. E., Ophoff, R. A., Pausova, Z., Sachdev, P. S., Saykin, A. J., Wright, M. J., Thompson, P. M., Schumann, G. & Desrivières, S., 6 Dec 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  54. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R. F., Stevenson, A. J., Cox, S. R., McCartney, D. L., Harris, S. E., Seeboth, A., Higham, J., Sproul, D., Taylor, A. M., Redmond, P., Corley, J., Pattie, A., del C. Valdés Hernández, M., Muñoz-Maniega, S., Bastin, M. E., Wardlaw, J., Horvath, S., Ritchie, C. W., Spires-Jones, T. L., McIntosh, A. M. & 3 others, Evans, K. L., Deary, I. & Marioni, R. E., 3 Dec 2019, In : Molecular Psychiatry. 11 p.

    Research output: Contribution to journalArticle

  55. A novel genetic locus influencing retinal venular tortuosity is also associated with risk of coronary artery disease

    Veluchamy, A., Ballerini, L., Vitart, V., Schraut, K. E., Kirin, M., Campbell, H., Joshi, P., Relan, D., Harris, S., Brown, E., Vaidya, S. S., Dhillon, B., Zhou, K., Pearson, E. R., Hayward, C., Polasek, O., Deary, I., MacGillivray, T., Wilson, J., Trucco, E. & 2 others, Palmer, C. N. A. & Doney, A. S. F., Dec 2019, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 12, p. 2542-2552

    Research output: Contribution to journalArticle

  56. Retinal microvascular features and cognitive change in the Lothian Birth Cohort 1936

    McGrory, S., Ballerini, L., Okely, J., Ritchie, S., Doubal, F., Doney, A. S. F., Starr, J., MacGillivray, T., Trucco, E., Wardlaw, J. & Deary, I., Dec 2019, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 500-509 10 p.

    Research output: Contribution to journalArticle

  57. Limited One-time Sampling Irregularity Map (LOTS-IM) for Automatic Unsupervised Assessment of White Matter Hyperintensities and Multiple Sclerosis Lesions in Structural Brain Magnetic Resonance Images

    Rachmadi, M. F., Del C. Valdés-hernández, M., Li, H., Guerrero, R., Meijboom, R., Wiseman, S., Waldman, A., Zhang, J., Rueckert, D., Wardlaw, J. & Komura, T., 27 Nov 2019, In : Computerized Medical Imaging and Graphics. 79, 101685.

    Research output: Contribution to journalArticle

  58. Preventing foot ulceration in diabetes: systematic review and meta-analyses of RCT data

    Crawford, F., Nicolson, D. J., Amanna, A. E., Martin, A., Gupta, S., Leese, G. P., Heggie, R., Chappell, F. M. & Mcintosh, H. H., 27 Nov 2019, In : Diabetologia. 63, 1, p. 49-64

    Research output: Contribution to journalArticle

  59. Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative

    De Guio, F., Duering, M., Fazekas, F., De Leeuw, F., Greenberg, S. M., Pantoni, L., Aghetti, A., Smith, E. E., Wardlaw, J. & Jouvent, E., 20 Nov 2019, In : Journal of Cerebral Blood Flow and Metabolism. p. 0271678X1988896

    Research output: Contribution to journalReview article

  60. Three-Dimensional Shape Modeling and Analysis of Brain Structures

    Kim, J., Valdés Hernández, M. D. C. & Park, J., 14 Nov 2019, In : Journal of Visualized Experiments. 153

    Research output: Contribution to journalArticle

  61. Analysis of dynamic texture and spatial spectral descriptors of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease

    Bernal, J., Valdés-hernández, M. D. C., Escudero, J., Viksne, L., Heye, A. K., Armitage, P. A., Makin, S., Touyz, R. M. & Wardlaw, J. M., 13 Nov 2019, In : Magnetic Resonance Imaging.

    Research output: Contribution to journalArticle

  62. Profile of and risk factors for poststroke cognitive impairment in diverse ethno-regional groups

    for the Stroke and Cognition (STROKOG) Collaboration, 11 Nov 2019, In : Neurology. p. 10.1212/WNL.0000000000008612

    Research output: Contribution to journalArticle

  63. Predictors of Lesion Cavitation After Recent Small Subcortical Stroke

    Gattringer, T., Valdes Hernandez, M., Heye, A., Armitage, P. A., Makin, S., Chappell, F., Pinter, D., Doubal, F., Enzinger, C., Fazekas, F. & Wardlaw, J. M., 8 Nov 2019, In : Translational Stroke Research.

    Research output: Contribution to journalArticle

  64. Modelling Direct Brain Cooling for Acute Ischaemic Stroke with the Vascular-Porous Model

    Fulford, L., Marshall, I., Andrews, P. & Valluri, P., Nov 2019.

    Research output: Contribution to conferenceAbstract

  65. Genetic architecture of subcortical brain structures in 38,851 individuals

    Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., Van Der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., Den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-partida, G., Amin, N., Hilal, S., Nho, K., Mirza-schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., De Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., De Geus, E. J. C., Tsolaki, M., Erk, S., Van Eijk, K. R., Cavalleri, G. L., Van Der Wee, N. J. A., Mcintosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., Van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., Van Der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J., Simmons, A., Meyer-lindenberg, A., Cahn, W., Whelan, C. D., Van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., Van Tol, M., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., Van Rooij, D., Djurovic, S., Deary, I. J., Mcmahon, K. L., Müller-myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., Van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., Van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., Van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-seiferth, N., Hartman, C. A., Destefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., Van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., Decarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., 21 Oct 2019, In : Nature Genetics.

    Research output: Contribution to journalArticle

  66. Inspiring New Researchers in Stroke: The ESO Edinburgh Stroke Research Workshop

    Orav, K., Moullaali, T. J., Sandset, E. C., Doubal, F. & Whiteley, W., 15 Oct 2019, In : Stroke.

    Research output: Contribution to journalComment/debate

  67. Predicting the Evolution of White Matter Hyperintensities in Brain MRI using Generative Adversarial Networks and Irregularity Map

    Rachmadi, M., Valdes Hernandez, M., Makin, S., Wardlaw, J. & Komura, T., 10 Oct 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. Shen, D., Liu, T., Peters, T. M., Staib, L. H., Essert, C., Zhou, S., Yap, P-T. & Khan, A. (eds.). Springer, p. 146–154 9 p. (Lecture Notes in Computer Science (LNCS); vol. 11766).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  68. Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage: Data From the RIGHT-2 Trial

    Bath, P. M., Woodhouse, L. J., Krishnan, K., Appleton, J. P., Anderson, C. S., Berge, E., Cala, L., Dixon, M., England, T. J., Godolphin, P. J., Hepburn, T., Mair, G., Montgomery, A. A., Phillips, S. J., Potter, J., Price, C. I., Randall, M., Robinson, T. G., Roffe, C., Rothwell, P. M. & 7 others, Sandset, E. C., Sanossian, N., Saver, J. L., Siriwardena, A. N., Venables, G., Wardlaw, J. M. & Sprigg, N., 7 Oct 2019, In : Stroke.

    Research output: Contribution to journalArticle

  69. Mechanical thrombectomy in patients with acute ischemic stroke: A cost-effectiveness and value of implementation analysis

    Heggie, R., Wu, O., White, P., Ford, G. A., Wardlaw, J., Brown, M. M., Clifton, A. & Muir, K. W., 30 Sep 2019, In : International Journal of Stroke. p. 174749301987965

    Research output: Contribution to journalArticle

  70. Observer Agreement on Computed Tomography Perfusion Imaging in Acute Ischemic Stroke

    El-tawil, S., Mair, G., Huang, X., Sakka, E., Palmer, J., Ford, I., Kalra, L., Wardlaw, J. & Muir, K. W., 25 Sep 2019, In : Stroke.

    Research output: Contribution to journalArticle

  71. Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto

    Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B., Rowe, B. & 6 others, Joanette, Y., Hacke, W., Kuller, L., Dichgans, M., Endres, M. & Khachaturian, Z. S., 22 Sep 2019, In : International Journal of Stroke. p. 174749301987191

    Research output: Contribution to journalArticle

  72. Brain peak width of skeletonised mean diffusivity (PSMD) and cognitive function in later life

    Deary, I., Ritchie, S. J., Muñoz Maniega, S., Cox, S., Valdes Hernandez, M., Luciano, M., Starr, J., Wardlaw, J. & Bastin, M., 26 Jul 2019, In : Frontiers in psychiatry. 10, 524.

    Research output: Contribution to journalArticle

  73. Preventing dementia by preventing stroke: The Berlin Manifesto

    Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B., Rowe, B. & 6 others, Joanette, Y., Hacke, W., Kuller, L., Dichgans, M., Endres, M. & Khachaturian, Z. S., 18 Jul 2019, In : Alzheimer's & Dementia. 15, 7, p. 961-984

    Research output: Contribution to journalArticle

  74. Lowering blood pressure after acute intracerebral haemorrhage: protocol for a systematic review and meta-analysis using individual patient data from randomised controlled trials participating in the Blood Pressure in Acute Stroke Collaboration (BASC)

    Moullaali, T. J., Wang, X., Woodhouse, L. J., Law, Z. K., Delcourt, C., Sprigg, N., Krishnan, K., Robinson, T. G., Wardlaw, J. M., Al-shahi Salman, R., Berge, E., Sandset, E. C., Anderson, C. S. & Bath, P. M., 16 Jul 2019, In : BMJ Open. 9, 7, e030121.

    Research output: Contribution to journalArticle

  75. Structural neuroimaging differentiates vulnerability from disease manifestation in colombian families with Huntington’s disease

    C. Valdés Hernández, M., Abu‐hussain, J., Qiu, X., Priller, J., Parra Rodríguez, M., Pino, M., Báez, S. & Ibáñez, A., 5 Jul 2019, In : Brain and Behavior.

    Research output: Contribution to journalArticle

  76. Effects of Isosorbide Mononitrate and/or Cilostazol on Hematological Markers, Platelet Function, and Hemodynamics in Patients With Lacunar Ischaemic Stroke: Safety Data From the Lacunar Intervention-1 (LACI-1) Trial

    Appleton, J. P., Blair, G. W., Flaherty, K., Law, Z. K., May, J., Woodhouse, L. J., Doubal, F., Sprigg, N., Bath, P. M. & Wardlaw, J. M., 3 Jul 2019, In : Frontiers in Neurology. 10

    Research output: Contribution to journalArticle

  77. Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

    Al-Shahi Salman, R., Minks, D. P., Mitra, D., Rodrigues, M. A., Bhatnagar, P., du Plessis, J. C., Joshi, Y., Dennis, M. S., Murray, G. D., Newby, D. E., Sandercock, P. A. G., Sprigg, N., Stephen, J., Sudlow, C. L. M., Werring, D. J., Whiteley, W. N., Wardlaw, J. M., White, P. M. & RESTART collaboration, 1 Jul 2019, In : Lancet Neurology. 18, 7, p. 643-652 10 p.

    Research output: Contribution to journalArticle

  78. Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

    Microbleeds International Collaborative Network, Jul 2019, In : Lancet Neurology. 18, 7, p. 653-665 13 p.

    Research output: Contribution to journalArticle

  79. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

    RESTART collaboration & Wardlaw, J., 29 Jun 2019, In : The Lancet. 393, 10191, p. 2613-2623 11 p.

    Research output: Contribution to journalArticle

  80. Reaction time variability and brain white matter integrity

    Booth, T., Dykiert, D., Corley, J., Gow, A., Morrison, Z., Munoz-Maniega, S., Royle, N., Valdes Hernandez, M., Starr, J., Penke, L., Bastin, M., Wardlaw, J. & Deary, I., 28 Jun 2019, In : Neuropsychology. 33, 5, p. 642-657

    Research output: Contribution to journalArticle

  81. Dilated Saliency U-Net for White Matter Hyperintensities Segmentation Using Irregularity Age Map

    Jeong, Y., Rachmadi, M. F., Valdés-Hernández, M. D. C. & Komura, T., 27 Jun 2019, In : Frontiers in Aging Neuroscience. 11

    Research output: Contribution to journalArticle

  82. Factors associated with potentially serious incidental findings and with serious final diagnoses on multi-modal imaging in the UK Biobank Imaging Study: a prospective cohort study

    Sudlow, C., Gibson, L., Nolan, J., Littlejohns, T. J., Mathieu, E., Garratt, S., Doherty, N., Petersen, S. E., Harvey, N. C. W., Sellors, J., Allen, N. E., Wardlaw, J. & Jackson, C., 17 Jun 2019, In : PLoS ONE. 16, 6, e0218267.

    Research output: Contribution to journalArticle

  83. Evaluation of Enhanced Learning Techniques for Segmenting Ischaemic Stroke Lesions in Brain Magnetic Resonance Perfusion Images Using a Convolutional Neural Network Scheme

    Pérez Malla, C. U., Valdés Hernández, M. D. C., Rachmadi, M. F. & Komura, T., 29 May 2019, In : Frontiers in Neuroinformatics. 13, 33.

    Research output: Contribution to journalArticle

  84. Stability of estimated premorbid cognitive ability over time after minor stroke and its relationship with post-stroke cognitive ability

    McHutchison, C. A., Chappell, F. M., Makin, S., Shuler, K., Wardlaw, J. M. & Cvoro, V., 22 May 2019, In : Brain Sciences. 9, 5, p. 1-15 117.

    Research output: Contribution to journalArticle

  85. Cortical thickness, white matter hyperintensities, and cognition after stroke

    Dickie, D. A., Gardner, K., Wagener, A., Wyss, A., Arba, F., Wardlaw, J. M. & Dawson, J., 14 May 2019, In : International Journal of Stroke. p. 174749301985129

    Research output: Contribution to journalArticle

  86. Small vessel disease: mechanisms and clinical implications

    Wardlaw, J., Smith, C. & Dichgans, M., 13 May 2019, In : Lancet Neurology.

    Research output: Contribution to journalReview article

  87. Hierarchical Complexity of the Adult Human Structural Connectome

    Smith, K., Bastin, M., Cox, S., Valdes Hernandez, M., Wiseman, S., Escudero, J. & Sudlow, C., May 2019, In : NeuroImage. 191, p. 205-215

    Research output: Contribution to journalArticle

  88. Quantifying BBB leakage in small vessel disease: review and consensus recommendations

    Thrippleton, M., Backes, W. H., Sourbron, S., Ingrisch, M., van Osch, M. J. P., Dichgans, M., Fazekas, F., Ropele, S., Frayne, R., van Oostenbrugge, R. J., Smith, E. E. & Wardlaw, J., 25 Apr 2019, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  89. Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial

    Blair, G. W., Appleton, J. P., Flaherty, K., Doubal, F., Sprigg, N., Dooley, R., Richardson, C., Hamilton, I., Law, Z. K., Shi, Y., Stringer, M. S., Thrippleton, M. J., Boyd, J., Shuler, K., Bath, P. M. & Wardlaw, J. M., 23 Apr 2019, In : EClinicalMedicine.

    Research output: Contribution to journalArticle

  90. Are morphologic features of recent small subcortical infarcts related to specific etiologic aspects?

    Eppinger, S., Gattringer, T., Nachbaur, L., Fandler, S., Pirpamer, L., Ropele, S., Wardlaw, J., Enzinger, C. & Fazekas, F., 22 Apr 2019, In : Therapeutic Advances in Neurological Disorders.

    Research output: Contribution to journalArticle

  91. Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial

    Van Der Worp, H. B., Macleod, M. R., Bath, P. M., Bathula, R., Christensen, H., Colam, B., Cordonnier, C., Demotes-mainard, J., Durand-zaleski, I., Gluud, C., Jakobsen, J. C., Kallmünzer, B., Kollmar, R., Krieger, D. W., Lees, K. R., Michalski, D., Molina, C., Montaner, J., Roine, R. O., Petersson, J. & 8 others, Perry, R., Sprigg, N., Staykov, D., Szabo, I., Vanhooren, G., Wardlaw, J. M., Winkel, P. & Schwab, S., 20 Apr 2019, In : European Stroke Journal. p. 239698731984469

    Research output: Contribution to journalArticle

  92. Retinal microvasculature and cerebral small vessel disease in the Lothian Birth Cohort 1936 and Mild Stroke Study

    McGrory, S., Ballerini, L., Doubal, F., Staals, J., Allerhand, M., Valdes Hernandez, M., Wang, X., MacGillivray, T., Doney, A. S. F., Dhillon, B., Starr, J., Bastin, M., Trucco, E., Deary, I. & Wardlaw, J., 19 Apr 2019, In : Scientific Reports. 9, 1, p. 6320 6320.

    Research output: Contribution to journalArticle

  93. The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: design and multicenter pilot study

    Weaver, N., Zhao, L., Biesbroek, J. M., Kuijf, H. J., Aben, H. P., Bae, H-J., Caballero, M. Á. A., Chappell, F., Chen, C. P. L. H., Dichgans, M., Duering, M., Georgakis, M. K., van der Giessen, R. S., Gyanwalij, B., Hamilton, O., Hilalj, S., vom Hofe, E. M., De Kort, P. L. M., Koudstaal, P. J., Lam, B. Y. K. & 12 others, Lim, J-S., Makin, S., Mok, V. C. T., Shi, L., Valdes Hernandez, M., Venketasubramanian, N., Wardlaw, J., Wollenweber, F. A., Wong, A., Xue, X., Meta VCI Map Consortium & Biessels, G. J., 12 Apr 2019, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticle

  94. Combining Neurovascular and Neurodegenerative Magnetic Resonance Imaging Measures in Stroke

    Wyss, A., Dawson, J., Arba, F., Wardlaw, J. M., Dickie, D. A., Diener, H. C., Algra, A., Davis, S., Hankey, G., Lees, K. R., Ovbiagele, B. & Weir, C., 8 Apr 2019, In : Stroke.

    Research output: Contribution to journalArticle

  95. Percutaneous Vascular Interventions Versus Intravenous Thrombolytic Treatment for Acute Ischemic Stroke

    Lindekleiv, H., Bruins Slot, K. M. H., Wardlaw, J. M. & Berge, E., 2 Apr 2019, In : Stroke.

    Research output: Contribution to journalArticle

  96. Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke

    McHutchison, C. A., Cvoro, V., Makin, S., Chappell, F. M., Shuler, K. & Wardlaw, J. M., Apr 2019, In : Journal of Neurology, Neurosurgery & Psychiatry. 90, 4, p. 436-443

    Research output: Contribution to journalArticle

  97. It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis

    Appleton, J. P., Woodhouse, L. J., Belcher, A., Bereczki, D., Berge, E., Caso, V., Chang, H. M., Christensen, H. K., Collins, R., Gommans, J., Laska, A. C., Ntaios, G., Ozturk, S., Sare, G. M., Szatmari, S., Wang, Y., Wardlaw, J. M., Sprigg, N. & Bath, P. M., 19 Mar 2019, In : Stroke and Vascular Neurology. 4, 1, p. 28-35

    Research output: Contribution to journalArticle

  98. Identification of the presence of ischaemic stroke lesions by means of texture analysis on brain magnetic resonance images

    Ortiz-ramón, R., Valdés Hernández, M. D. C., González-castro, V., Makin, S., Armitage, P. A., Aribisala, B. S., Bastin, M. E., Deary, I. J., Wardlaw, J. M. & Moratal, D., 16 Mar 2019, In : Computerized Medical Imaging and Graphics. 74, p. 12-24

    Research output: Contribution to journalArticle

  99. Association between Striatal Brain Iron Deposition, Microbleeds and Cognition 1 Year After a Minor Ischaemic Stroke

    Valdés Hernández, M., Case, T., Chappell, F., Glatz, A., Makin, S., Doubal, F. & Wardlaw, J., 14 Mar 2019, In : International Journal of Molecular Sciences. 20, 6, p. 1293

    Research output: Contribution to journalArticle

  100. Associations between vascular risk factors and brain MRI indices in UK Biobank

    Cox, S., Lyall, D. M., Ritchie, S., Bastin, M., Harris, M., Buchanan, C. R., Fawns-Ritchie, C., Barbu, M., de Nooij, L., Reus, L. M., Alloza, C., Shen, X., Neilson, E., Alderson, H. L., Hunter, S., Liewald, D., Whalley, H. C., McIntosh, A., Lawrie, S., Pell, J. P. & 4 others, Tucker-Drob, E. M., Wardlaw, J., Gale, C. & Deary, I., 11 Mar 2019, In : European Heart Journal.

    Research output: Contribution to journalArticle

  101. A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

    Fetit, A. E., Doney, A. S., Hogg, S., Wang, R., Macgillivray, T., Wardlaw, J. M., Doubal, F. N., Mckay, G. J., Mckenna, S. & Trucco, E., 5 Mar 2019, In : Scientific Reports. 9, 1, p. 3591

    Research output: Contribution to journalArticle

  102. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration

    Smith, E. E., Biessels, G. J., De Guio, F., De Leeuw, F. E., Duchesne, S., Düring, M., Frayne, R., Ikram, M. A., Jouvent, E., Macintosh, B. J., Thrippleton, M. J., Vernooij, M. W., Adams, H., Backes, W. H., Ballerini, L., Black, S. E., Chen, C., Corriveau, R., Decarli, C., Greenberg, S. M. & 29 others, Gurol, M. E., Ingrisch, M., Job, D., Lam, B. Y. K., Launer, L. J., Linn, J., Mccreary, C. R., Mok, V. C. T., Pantoni, L., Pike, G. B., Ramirez, J., Reijmer, Y. D., Romero, J. R., Ropele, S., Rost, N. S., Sachdev, P. S., Scott, C. J. M., Seshadri, S., Sharma, M., Sourbron, S., Steketee, R. M. E., Swartz, R. H., Van Oostenbrugge, R., Van Osch, M., Van Rooden, S., Viswanathan, A., Werring, D., Dichgans, M. & Wardlaw, J. M., 26 Feb 2019, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 191-204

    Research output: Contribution to journalArticle

  103. VAMPIRE® fundus image analysis algorithms: Validation and diagnostic relevance in hypertensive cats

    Cirla, A., Drigo, M., Ballerini, L., Trucco, E. & Barsotti, G., 22 Feb 2019, In : Veterinary ophthalmology. p. 1-9

    Research output: Contribution to journalArticle

  104. WMH and long-term outcomes in ischemic stroke: a systematic review and meta-analysis

    Georgakis, M. K., Duering, M., Wardlaw, J. & Dichigans, M., 19 Feb 2019, In : Neurology.

    Research output: Contribution to journalArticle

  105. Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: A systematic review and meta-analysis

    Firdaus Francis, F., Ballerini, L. & Wardlaw, J., 14 Feb 2019, In : International Journal of Stroke.

    Research output: Contribution to journalReview article

  106. MRI Relaxometry for Quantitative Analysis of USPIO Uptake in Cerebral Small Vessel Disease

    Thrippleton, M., Blair, G., Valdes-hernandez, M., Glatz, A., Semple, S., Doubal, F., Vesey, A., Marshall, I., Newby, D. & Wardlaw, J., 12 Feb 2019, In : International Journal of Molecular Sciences. 20, 3, p. 776

    Research output: Contribution to journalArticle

  107. Manually-parcellated gyral data accounting for all known anatomical variability

    Mikhael, S., Mair, G., Valdes Hernandez, M., Hoogendoorn, C., Wardlaw, J., Bastin, M. & Pernet, C. R., 29 Jan 2019, In : Scientific Data. 6, 12 p., 190001.

    Research output: Contribution to journalArticle

  108. Brain morphometry and longitudinal relaxation time of spontaneously hypertensive rats (SHR) in early and intermediate stages of hypertension investigated by 3D VFA-SPGR MRI

    Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, M., Benveniste, H. & Lee, H., 26 Jan 2019, In : Neuroscience.

    Research output: Contribution to journalArticle

  109. Effect of Glyceryl Trinitrate on Hemodynamics in Acute Stroke: Data From the ENOS Trial

    ENOS Investigators, 10 Jan 2019, In : Stroke.

    Research output: Contribution to journalArticle

  110. Convolutional Neural Networks for Direct Inference of Pharmacokinetic Parameters: Application to Stroke Dynamic Contrast-Enhanced MRI

    Ulas, C., Das, D., Thrippleton, M. J., Valdés Hernández, M. D. C., Armitage, P. A., Makin, S. D., Wardlaw, J. M. & Menze, B. H., 8 Jan 2019, In : Frontiers in Neurology. 9

    Research output: Contribution to journalArticle

  111. Vascular contributions to cognitive impairment and dementia: Research consortia that focus on etiology and treatable targets to lessen the burden of dementia worldwide

    Gladman, J. T., Corriveau, R. A., Debette, S., Dichgans, M., Greenberg, S. M., Sachdev, P. S., Wardlaw, J. M. & Biessels, G. J., 1 Jan 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, C, p. 789-796

    Research output: Contribution to journalArticle

  112. Stroke research in 2018: extended time windows, refined benefit, and lifestyle prevention targets

    Wardlaw, J. M. & Bath, P. M., Jan 2019, In : Lancet Neurology. 18, 1, p. 2-3

    Research output: Contribution to journalComment/debate

  113. Vascular dysfunction – the disregarded partner of Alzheimer’s disease

    Sweeney, M., Doubal, F., Salman, R. & Wardlaw, J., Jan 2019, In : Alzheimer's & Dementia. 15, 1

    Research output: Contribution to journalComment/debate

  114. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

    Chauhan, G., Adams, H. H. H., Satizabal, C. L., Bis, J. C., Teumer, A., Sargurupremraj, M., Hofer, E., Trompet, S., Hilal, S., Smith, A. V., Jian, X., Malik, R., Traylor, M., Pulit, S. L., Amouyel, P., Mazoyer, B., Zhu, Y., Kaffashian, S., Schilling, S., Beecham, G. W. & 130 others, Montine, T. J., Schellenberg, G. D., Kjartansson, O., Guðnason, V., Knopman, D. S., Griswold, M. E., Windham, B. G., Gottesman, R. F., Mosley, T. H., Schmidt, R., Saba, Y., Schmidt, H., Takeuchi, F., Yamaguchi, S., Nabika, T., Kato, N., Rajan, K. B., Aggarwal, N. T., De Jager, P. L., Evans, D. A., Psaty, B. M., Rotter, J. I., Rice, K., Lopez, O. L., Liao, J., Chen, C., Cheng, C., Wong, T. Y., Ikram, M. K., Van Der Lee, S. J., Amin, N., Chouraki, V., Destefano, A. L., Aparicio, H. J., Romero, J. R., Maillard, P., Decarli, C., Wardlaw, J. M., Hernández, M. D. C. V., Luciano, M., Liewald, D., Deary, I. J., Starr, J. M., Bastin, M. E., Muñoz Maniega, S., Slagboom, P. E., Beekman, M., Deelen, J., Uh, H., Lemmens, R., Brodaty, H., Wright, M. J., Ames, D., Boncoraglio, G. B., Hopewell, J. C., Beecham, A. H., Blanton, S. H., Wright, C. B., Sacco, R. L., Wen, W., Thalamuthu, A., Armstrong, N. J., Chong, E., Schofield, P. R., Kwok, J. B., Van Der Grond, J., Stott, D. J., Ford, I., Jukema, J. W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Van Der Lugt, A., Wittfeld, K., Grabe, H. J., Hosten, N., Von Sarnowski, B., Völker, U., Levi, C., Jimenez-conde, J., Sharma, P., Sudlow, C. L. M., Rosand, J., Woo, D., Cole, J. W., Meschia, J. F., Slowik, A., Thijs, V., Lindgren, A., Melander, O., Grewal, R. P., Rundek, T., Rexrode, K., Rothwell, P. M., Arnett, D. K., Jern, C., Johnson, J. A., Benavente, O. R., Wasssertheil-smoller, S., Lee, J., Wong, Q., Mitchell, B. D., Rich, S. S., Mcardle, P. F., Geerlings, M. I., Van Der Graaf, Y., De Bakker, P. I. W., Asselbergs, F. W., Srikanth, V., Thomson, R., Mcwhirter, R., Moran, C., Callisaya, M., Phan, T., Rutten-jacobs, L. C. A., Bevan, S., Tzourio, C., Mather, K. A., Sachdev, P. S., Van Duijn, C. M., Worrall, B. B., Dichgans, M., Kittner, S. J., Markus, H. S., Ikram, M. A., Fornage, M., Launer, L. J., Seshadri, S., Longstreth, W. T. & Debette, S., 2019, In : Neurology.

    Research output: Contribution to journalArticle

  115. 2018
  116. Childhood neurodevelopment after prescription of maintenance methadone for opioid dependency in pregnancy: a systematic review and meta-analysis

    Monnelly, V. J., Hamilton, R., Chappell, F. M., Mactier, H. & Boardman, J. P., 3 Dec 2018, In : Developmental medicine and child neurology.

    Research output: Contribution to journalReview article

  117. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

    Franceschini, N., Giambartolomei, C., De Vries, P. S., Finan, C., Bis, J. C., Huntley, R. P., Lovering, R. C., Tajuddin, S. M., Winkler, T. W., Graff, M., Kavousi, M., Dale, C., Smith, A. V., Hofer, E., Van Leeuwen, E. M., Nolte, I. M., Lu, L., Scholz, M., Sargurupremraj, M., Pitkänen, N. & 137 others, Franzén, O., Joshi, P. K., Noordam, R., Marioni, R. E., Hwang, S., Musani, S. K., Schminke, U., Palmas, W., Isaacs, A., Correa, A., Zonderman, A. B., Hofman, A., Teumer, A., Cox, A. J., Uitterlinden, A. G., Wong, A., Smit, A. J., Newman, A. B., Britton, A., Ruusalepp, A., Sennblad, B., Hedblad, B., Pasaniuc, B., Penninx, B. W., Langefeld, C. D., Wassel, C. L., Tzourio, C., Fava, C., Baldassarre, D., O’leary, D. H., Teupser, D., Kuh, D., Tremoli, E., Mannarino, E., Grossi, E., Boerwinkle, E., Schadt, E. E., Ingelsson, E., Veglia, F., Rivadeneira, F., Beutner, F., Chauhan, G., Heiss, G., Snieder, H., Campbell, H., Völzke, H., Markus, H. S., Deary, I. J., Jukema, J. W., De Graaf, J., Price, J., Pott, J., Hopewell, J. C., Liang, J., Thiery, J., Engmann, J., Gertow, K., Rice, K., Taylor, K. D., Dhana, K., Kiemeney, L. A. L. M., Lind, L., Raffield, L. M., Launer, L. J., Holdt, L. M., Dörr, M., Dichgans, M., Traylor, M., Sitzer, M., Kumari, M., Kivimaki, M., Nalls, M. A., Melander, O., Raitakari, O., Franco, O. H., Rueda-ochoa, O. L., Roussos, P., Whincup, P. H., Amouyel, P., Giral, P., Anugu, P., Wong, Q., Malik, R., Rauramaa, R., Burkhardt, R., Hardy, R., Schmidt, R., De Mutsert, R., Morris, R. W., Strawbridge, R. J., Wannamethee, S. G., Hägg, S., Shah, S., Mclachlan, S., Trompet, S., Seshadri, S., Kurl, S., Heckbert, S. R., Ring, S., Harris, T. B., Lehtimäki, T., Galesloot, T. E., Shah, T., De Faire, U., Plagnol, V., Rosamond, W. D., Post, W., Zhu, X., Zhang, X., Guo, X., Saba, Y., Dehghan, A., Seldenrijk, A., Morrison, A. C., Hamsten, A., Psaty, B. M., Van Duijn, C. M., Lawlor, D. A., Mook-kanamori, D. O., Bowden, D. W., Schmidt, H., Wilson, J. G., Rotter, J. I., Wardlaw, J. M., Deanfield, J., Halcox, J., Lyytikäinen, L., Loeffler, M., Evans, M. K., Debette, S., Humphries, S. E., Völker, U., Gudnason, V., Hingorani, A. D., Björkegren, J. L. M., Casas, J. P. & O’donnell, C. J., 3 Dec 2018, In : Nature Communications. 9, 1, 5141.

    Research output: Contribution to journalArticle

  118. Baseline characteristics of the 1149 patients recruited into the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) randomized controlled trial

    Bath, P. M., Scutt, P., Appleton, J. P., Dixon, M., Woodhouse, L. J., Wardlaw, J. M. & Sprigg, N., 26 Nov 2018, In : International Journal of Stroke. p. 1747493018816451

    Research output: Contribution to journalArticle

  119. Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis

    Gibson, L. M., Paul, L., Chappell, F. M., MacLeod, M., Whiteley, W. N., Salman, R. A-S., Wardlaw, J. M. & Sudlow, C. L. M., 22 Nov 2018, In : British Medical Journal (BMJ). 363, 8177, 10 p., k4577.

    Research output: Contribution to journalArticle

  120. Central masked adjudication of stroke diagnosis at trial entry offered no advantage over diagnosis by local clinicians: Secondary analysis and simulation

    Godolphin, P. J., Hepburn, T., Sprigg, N., Walker, L., Berge, E., Collins, R., Gommans, J., Ntaios, G., Pocock, S., Prasad, K., Wardlaw, J. M., Bath, P. M. & Montgomery, A. A., 10 Nov 2018, In : Contemporary clinical trials communications. 12, p. 176-181

    Research output: Contribution to journalArticle

  121. Secondary prevention of Alzheimer's dementia: neuroimaging contributions

    Ten Kate, M., Ingala, S., Schwarz, A. J., Fox, N. C., Chételat, G., van Berckel, B. N. M., Ewers, M., Foley, C., Gispert, J. D., Hill, D., Irizarry, M. C., Lammertsma, A. A., Molinuevo, J. L., Ritchie, C., Scheltens, P., Schmidt, M. E., Visser, P. J., Waldman, A., Wardlaw, J., Haller, S. & 1 others, Barkhof, F., 30 Oct 2018, In : Alzheimer's research & therapy. 10, 1, p. 112

    Research output: Contribution to journalReview article

  122. Action Plan for Stroke in Europe 2018–2030

    Norrving, B., Barrick, J., Davalos, A., Dichgans, M., Cordonnier, C., Guekht, A., Kutluk, K., Mikulik, R., Wardlaw, J., Richard, E., Nabavi, D., Molina, C., Bath, P. M., Stibrant Sunnerhagen, K., Rudd, A., Drummond, A., Planas, A. & Caso, V., 29 Oct 2018, In : European Stroke Journal. p. 239698731880871

    Research output: Contribution to journalArticle

  123. Effect of IV alteplase on the ischemic brain lesion at 24-48 hours after ischemic stroke

    IST-3 Collaborative Group, Mair, G., von Kummer, R., Morris, Z., von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A., Adami, A., Potter, G., Sandercock, P., Lindley, R. I. & Wardlaw, J., 26 Oct 2018, In : Neurology.

    Research output: Contribution to journalArticle

  124. Percutaneous vascular interventions versus intravenous thrombolytic treatment for acute ischaemic stroke

    Lindekleiv, H., Berge, E., Bruins Slot, K. M. & Wardlaw, J. M., 26 Oct 2018, In : The Cochrane Library.

    Research output: Contribution to journalReview article

  125. Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow

    Shi, Y., Thrippleton, M. J., Blair, G. W., Dickie, D. A., Marshall, I., Hamilton, I., Doubal, F. N., Chappell, F. & Wardlaw, J. M., 8 Oct 2018, In : Journal of Cerebral Blood Flow and Metabolism. p. 0271678X1880395

    Research output: Contribution to journalArticle

  126. Investigating pedestrian navigation in indoor open space environments using big data

    Lovreglio, R., Charitha, D., Xiang, S. & Ballerini, L., Oct 2018, In : Applied mathematical modelling. 62, p. 499-509

    Research output: Contribution to journalArticle

  127. The association between carotid atheroma and cerebral cortex structure at age 73

    Alhusaini, S., Karama, S., Nguyen, T-V., Thiel, A., Bernhardt, B., Cox, S., Corley, J., Taylor, A., Evans, A. C., Starr, J., Bastin, M., Wardlaw, J., Deary, I. & Ducharme, S., Oct 2018, In : Annals of Neurology. 84, 4, p. 576-587

    Research output: Contribution to journalArticle

  128. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

    Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., Saba, Y., Luciano, M., Bernard, M., Trompet, S., Yang, J., Gillespie, N. A., Van Der Lee, S. J., Neumann, A., Ahmad, S., Andreassen, O. A. & 71 others, Ames, D., Amin, N., Arfanakis, K., Bastin, M. E., Becker, D. M., Beiser, A. S., Beyer, F., Brodaty, H., Bryan, R. N., Bülow, R., Dale, A. M., De Jager, P. L., Deary, I. J., Decarli, C., Fleischman, D. A., Gottesman, R. F., Van Der Grond, J., Gudnason, V., Harris, T. B., Homuth, G., Knopman, D. S., Kwok, J. B., Lewis, C. E., Li, S., Loeffler, M., Lopez, O. L., Maillard, P., El Marroun, H., Mather, K. A., Mosley, T. H., Muetzel, R. L., Nauck, M., Nyquist, P. A., Panizzon, M. S., Pausova, Z., Psaty, B. M., Rice, K., Rotter, J. I., Royle, N., Satizabal, C. L., Schmidt, R., Schofield, P. R., Schreiner, P. J., Sidney, S., Stott, D. J., Thalamuthu, A., Uitterlinden, A. G., Valdés Hernández, M. C., Vernooij, M. W., Wen, W., White, T., Witte, A. V., Wittfeld, K., Wright, M. J., Yanek, L. R., Tiemeier, H., Kremen, W. S., Bennett, D. A., Jukema, J. W., Paus, T., Wardlaw, J. M., Schmidt, H., Sachdev, P. S., Villringer, A., Grabe, H. J., Longstreth, W. T., Van Duijn, C. M., Launer, L. J., Seshadri, S., Ikram, M. A. & Fornage, M., 26 Sep 2018, In : Nature Communications. 9, 1, 3945.

    Research output: Contribution to journalArticle

  129. Automatic Irregular Texture Detection in Brain MRI without Human Supervision

    Rachmadi, M., Valdes Hernandez, M. & Komura, T., 13 Sep 2018, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018. Granada, Spain: Springer, Cham, p. 506-513 8 p. (Lecture Notes in Computer Science; vol. 11072)(Image Processing, Computer Vision, Pattern Recognition, and Graphics; vol. 11072).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  130. Transfer Learning for Task Adaptation of Brain Lesion Assessment and Prediction of Brain Abnormalities Progression/Regression Using Irregularity Age Map in Brain MRI

    Rachmadi, M., Valdes Hernandez, M. & Komura, T., 13 Sep 2018, PRIME: International Workshop on PRedictive Intelligence In MEdicine. Granada, Spain: Springer, Cham, p. 85-93 9 p. (Lecture Notes in Computer Science; vol. 11121)(Image Processing, Computer Vision, Pattern Recognition, and Graphics; vol. 11121).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  131. Reproducibility of Transcranial Doppler ultrasound in the middle cerebral artery

    Kaczynski, J., Home, R., Shields, K., Walters, M., Whiteley, W., Wardlaw, J. & Newby, D. E., 11 Sep 2018, In : Cardiovascular ultrasound. 16, 1, p. 15

    Research output: Contribution to journalArticle

  132. Considerations on accuracy, pattern and possible underlying factors of brain microbleeds progression on older adults with absence or mild presence of vascular pathology

    Alzheimer’s Disease Neuroimaging Initiative, 1 Sep 2018, In : Journal of International Medical Research. 21 p.

    Research output: Contribution to journalArticle

  133. The key challenges of discussing end-of life stroke care with patients and families: a mixed-methods electronic survey of hospital and community healthcare professionals

    Doubal, F., Cowey, E., Bailey, F., Murray, S., Borthwick, S., Somerville, M., Lerpiniere, C., Reid, L., Boyd, K., Hynd, G. & Mead, G., 1 Sep 2018, In : Journal of the Royal College of Physicians of Edinburgh. 48, 3, p. 217-224

    Research output: Contribution to journalArticle

  134. Longitudinal serum S100β and brain ageing in the Lothian Birth Cohort 1936

    Cox, S., Allerhand, M., Ritchie, S. J., Muñoz Maniega, S., Valdes Hernandez, M., Harris, S., Dickie, D. A., Anblagan, D., Aribisala, B., Morris, Z., Sherwood, R., Abbott, N. J., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Sep 2018, In : Neurobiology of Aging. 69, p. 274-282

    Research output: Contribution to journalArticle

  135. Do 2-year changes in superior frontal gyrus and global brain atrophy affect cognition?

    The Alzheimer’s Disease Neuroimaging Initiative, 30 Aug 2018, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 10

    Research output: Contribution to journalArticle

  136. Impact of detecting potentially serious incidental findings during multi-modal imaging: [version 3; peer review: 2 approved, 1 approved with reservations]

    Gibson, L. M., Littlejohns, T. J., Adamska, L., Garratt, S., Doherty, N., Wardlaw, J. M., Maskell, G., Parker, M., Brownsword, R., Matthews, P. M., Collins, R., Allen, N. E., Sellors, J. & Sudlow, C., 2 Aug 2018, In : Wellcome Open Research . 2, p. 114

    Research output: Contribution to journalArticle

  137. Using orthogonal locality preserving projections to find dominant features for classifying retinal blood vessels

    Relan, D., Ballerini, L., Trucco, E. & MacGillivray, T., 1 Aug 2018, In : Multimedia Tools and Applications. p. 1-21

    Research output: Contribution to journalArticle

  138. Widespread associations between trait conscientiousness and thickness of brain cortical regions

    Lewis, G. J., Dickie, D. A., Cox, S. R., Karama, S., Evans, A. C., Starr, J. M., Bastin, M. E., Wardlaw, J. M. & Deary, I. J., 1 Aug 2018, In : NeuroImage. 176, p. 22-28

    Research output: Contribution to journalArticle

  139. Exome chip analysis identifies low-frequency and rare variants in MRPL38 for white matter hyperintensities on brain MRI

    Jian, X., Satizabal, C. L., Smith, A. V., Wittfield, K., Bis, J. C., Smith, J., Hsu, F-C., Nho, K., Hofer, E., Hagenaars, S., Nyquist, P. A., Mishra, A., Adams, H. H. H., Li, S., Teumer, A., Zhao, W., Freedman, B. I., Saba, Y., Yanek, L. R., Chauhan, G. & 58 others, Van Buchem, M. A., Cushman, M., Royle, N., Bryan, R. N., Niessen, W. J., Windham, B. G., DeStefano, A. L., Habes, M., Heckbert, S. R., Palmer, N. D., Lewis, C. E., Eiriksdottir, G., Maillard, P., Mathias, R. A., Homuth, G., Valdes Hernandez, M., Divers, J., Beiser, A. S., Langner, S., Rice, K. M., Bastin, M., Yang, Q., Maldjan, J. A., Starr, J., Sidney, S. S., Risacher, S. L., Uitterlinden, A. G., Gudnason, V., Nauck, M., Rotter, J. I., Schreiner, P. J., Boerwinkle, E., van Duijn, C., Mazoyer, B., von Sarnowski, B., Gottesman, R. F., Levy, D., Sigurdsson, S., Vernooij, M. W., Turner, S. T., Schmidt, R., Wardlaw, J., Psaty, B. M., Mosley, T. H., DeCarli, C., Saykin, A. J., Bowden, D. W., Becker, D. M., Deary, I., Schmidt, H., Kardia, S. L. R., Ikram, M. A., Debette, S., Grabe, H. J., Longstreth, W. T., Seshadri, S., Launer, L. J. & Fornage, M., 12 Jul 2018, In : Stroke. 49, 8, p. 1812-1819

    Research output: Contribution to journalArticle

  140. The Glymphatic System and Waste Clearance with Brain Aging: A Review

    Benveniste, H., Liu, X., Koundal, S., Sanggaard, S., Lee, H. & Wardlaw, J., 11 Jul 2018, In : Gerontology. p. 1-14 14 p.

    Research output: Contribution to journalReview article

  141. Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

    Rajani, R. M., Quick, S., Ruigrok, S. R., Graham, D., Harris, S. E., Verhaaren, B. F. J., Fornage, M., Seshadri, S., Atanur, S. S., Dominiczak, A. F., Smith, C., Wardlaw, J. M. & Williams, A., 4 Jul 2018, In : Science Translational Medicine. 10, 448, 12 p., eaam9507.

    Research output: Contribution to journalArticle

  142. The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke

    Loos, C. M. J., McHutchison, C., Cvoro, V., Makin, S., Staals, J., Chappell, F., Dennis, M., van Oostenbrugge, R. J. & Wardlaw, J., 1 Jul 2018, In : International Journal of Stroke. 13, 5, p. 518-524

    Research output: Contribution to journalArticle

  143. William M. Feinberg Award for Excellence in Clinical Stroke: Small Vessel Disease; a Big Problem, But Fixable

    Wardlaw, J. M., 12 Jun 2018, In : Stroke. 49, 7, p. 1770-1775

    Research output: Contribution to journalArticle

  144. Neurological Disease in Lupus: Toward a Personalized Medicine Approach

    Mcglasson, S., Wiseman, S., Wardlaw, J., Dhaun, N. & Hunt, D. P. J., 6 Jun 2018, In : Frontiers in Immunology. 9

    Research output: Contribution to journalReview article

  145. Characterisation of tissue-type metabolic content in Secondary Progressive Multiple Sclerosis: a Magnetic Resonance Spectroscopic Imaging study

    MS-SMART Trialists, 30 May 2018, In : Journal of Neurology.

    Research output: Contribution to journalArticle

  146. Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium

    Kong, X-Z., Mathias, S. R., Guadalupe, T., Glahn, D. C., Franke, B., Crivello, F., Tzourio-Mazoyer, N., Fisher, S. E., Thompson, P. M., Francks, C., ENIGMA Laterality Working Group, Valdes Hernandez, M., Wardlaw, J., Harris, M. & Luciano, M., 29 May 2018, In : Proceedings of the National Academy of Sciences (PNAS). 115, 22, p. E5154-E5163

    Research output: Contribution to journalArticle

  147. Fourth European stroke science workshop

    Debette, S., Strbian, D., Wardlaw, J., Van Der Worp, H., Rinkel, G., Caso, V., Dichgans, M., Tournier-lasserve, E., Grefkes, C., Kelly, P., Muir, K., Berge, E., Trégouët, D., Roffe, C., Brainin, M., Beck, J., Steiner, T., De Lau, L., Jouvent, E., Veltkamp, R. & 26 others, Baron, J., Nedeltchev, K., Bath, P., Quinn, T., Richard, E., Ziemann, U., Liesz, A., Ntaios, G., Iadecola, C., Lees, K., Christensen, H. K., Van Veluw, S., Endres, M., Anderson, C., Molina, C., Düring, M., Dufouil, C., Ostergaard, L., Samani, N., Fischer, U., De Leeuw, F., Norrving, B., Biessels, G., Cordonnier, C., Mas, J. & Mattle, H., 24 May 2018, In : European Stroke Journal. 3, 3, p. 206-219

    Research output: Contribution to journalComment/debate

  148. Rapid automated quantification of cerebral leukoaraiosis on CT images: A Multicenter Validation Study

    Chen, L., Carlton Jones, A. L., Mair, G., Patel, R., Gontsarova, A., Ganesalingam, J., Math, N., Dawson, A., Basaam, A., Cohen, D., Mehta, A., Wardlaw, J., Rueckert, D., Bentley, P. & IST-3 Collaborative Group, 15 May 2018, In : Radiology.

    Research output: Contribution to journalArticle

  149. Longitudinal MRI dynamics of recent small subcortical infarcts and possible predictors

    Pinter, D., Gattringer, T., Enzinger, C., Seifert-Held, T., Kneihsl, M., Fandler, S., Pichler, A., Barro, C., Eppinger, S., Pirpamer, L., Bachmaier, G., Ropele, S., Wardlaw, J., Kuhle, J., Khalil, M. & Fazekas, F., 8 May 2018, In : Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalArticle

  150. Voxel-Based Irregularity Age Map (IAM) for Brain’s White Matter Hyperintensities in MRI

    Rachmadi, M., Valdes Hernandez, M., Komura, T. & Alzheimer’s Disease Neuroimaging Initiative, 7 May 2018, 2017 International Conference on Advanced Computer Science and Information Systems (ICACSIS). Institute of Electrical and Electronics Engineers (IEEE)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  151. Cognitive function, disease burden and the structural connectome in systemic lupus erythematosus

    Wiseman, S., Bastin, M., Amft, E., Belch, J. F. F., Ralston, S. & Wardlaw, J., 3 May 2018, In : Lupus.

    Research output: Contribution to journalArticle

  152. Protocol for a prospective collaborative systematic review and meta-analysis of individual patient data from randomized controlled trials of vasoactive drugs in acute stroke: The Blood pressure in Acute Stroke Collaboration, stage-3

    Sandset, E. C., Sanossian, N., Woodhouse, L. J., Anderson, C., Berge, E., Lees, K. R., Potter, J. F., Robinson, T. G., Sprigg, N., Wardlaw, J. M., Bath, P. M. & Blood pressure in Acute Stroke Collaboration Investigators, 3 May 2018, In : International Journal of Stroke. p. 1747493018772733

    Research output: Contribution to journalArticle

  153. Understanding the role of the perivascular space in cerebral small vessel disease

    Brown, R., Benveniste, H., Black, S. E., Charpak, S., Dichgans, M., Joutel, A., Nedergaard, M., Smith, K. J., Zlokovic, B. V. & Wardlaw, J. M., 2 May 2018, In : Cardiovascular Research.

    Research output: Contribution to journalArticle

  154. A large margin algorithm for automated segmentation of white matter hyperintensity

    Qin, C., Guerrero, R., Bowles, C., Chen, L., Dickie, D. A., Valdes-hernandez, M. D. C., Wardlaw, J. & Rueckert, D., May 2018, In : Pattern Recognition. 77, p. 150-159

    Research output: Contribution to journalArticle

  155. 'Small vessels, dementia and chronic diseases -molecular mechanisms and pathophysiology' Workshop proceedings

    Horsburgh, K., Wardlaw, J., Van Agtmael, T., Allan, S., Ashford, M., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davies, J. B., Duncombe, J., Farr, T. D., Fowler, J., Goense, J., Granata, A., Hall, C., Hainsworth, A., Harvey, A., Hawkes, C. & 26 others, Joutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., MacLeod, M., Macrae, M., Markus, H. S., McCabe, C., McColl, B., Meakin, P. J., Miller, A. A., Nedergaard, M., O'Sullivan, M., Quinn, T., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R., Trueman, R., Wang, T., Williams, A., Williams, S. & Work, L. M., 30 Apr 2018, In : Clinical science. 132, 8, p. 851-868

    Research output: Contribution to journalReview article

  156. The Brain Health Index: Towards a combined measure of neurovascular and neurodegenerative structural brain injury

    Dickie, D. A., Valdes Hernandez, M., Makin, S., Staals, J., Wiseman, S., Bastin, M. & Wardlaw, J., 19 Apr 2018, In : International Journal of Stroke.

    Research output: Contribution to journalArticle

  157. Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease

    Bailey, E. L., Mcbride, M. W., Mcclure, J. D., Beattie, W., Graham, D., Dominiczak, A. F., Smith, C. & Wardlaw, J., 9 Apr 2018, In : Clinical science.

    Research output: Contribution to journalArticle

  158. Direct Estimation of Pharmacokinetic Parameters from DCE-MRI using Deep CNN with Forward Physical Model Loss

    Ulas, C., Tetteh, G., Thrippleton, M. J., Armitage, P. A., Makin, S. D., Wardlaw, J. M., Davies, M. E. & Menze, B. H., 8 Apr 2018.

    Research output: Contribution to conferencePaper

  159. Towards standardization of quantitative retinal vascular parameters: Comparison of SIVA and VAMPIRE measurements in the Lothian Birth Cohort 1936

    McGrory, S., Taylor, A., Pellegrini, E., Ballerini, L., Kirin, M., Doubal, F., Wardlaw, J., Doney, A. S. F., Dhillon, B., Starr, J., Trucco, E., Deary, I. & MacGillivray, T., 23 Mar 2018, In : Translational Vision Science and Technology. 7, 12

    Research output: Contribution to journalArticle

  160. Long-term morphological changes of symptomatic lacunar infarcts and surrounding white matter on structural MRI

    Loos, C. M. J., Makin, S., Staals, J., Dennis, M., van Oostenbrugge, R. J. & Wardlaw, J., 22 Mar 2018, In : Stroke.

    Research output: Contribution to journalArticle

  161. The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage with cerebral amyloid angiopathy: model development and diagnostic test accuracy study

    Rodrigues, M. A., Samarasekera, N., Lerpiniere, C., Humphreys, C., McCarron, M. O., White, P. M., Nicoll, J. A. R., Sudlow, C. L. M., Cordonnier, C., Wardlaw, J., Smith, C. & Salman, R. A-S., 1 Mar 2018, In : Lancet Neurology. 17, 3, p. 232-240 9 p.

    Research output: Contribution to journalArticle

  162. Segmentation of White Matter Hyperintensities using Convolutional Neural Networks with Global Spatial Information in Routine Clinical Brain MRI with None or Mild Vascular Pathology

    Rachmadi, M., Valdes Hernandez, M., Agan, M. L. F., Di Perri, C., Komura, T. & Alzheimer's Disease Neuroimaging Initiative, 17 Feb 2018, In : Computerized Medical Imaging and Graphics.

    Research output: Contribution to journalArticle

  163. Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering

    Ballerini, L., Lovreglio, R., Valdes Hernandez, M., Ramirez, J., MacIntosh, B., Black, S. & Wardlaw, J., 1 Feb 2018, In : Scientific Reports. 8, 2132.

    Research output: Contribution to journalArticle

  164. Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’

    Scutt, P., Appleton, J. P., Dixon, M. S., Woodhouse, L. J., Sprigg, N., Wardlaw, J. M., Montgomery, A. A., Pocock, S. J. & Bath, P. M., 1 Feb 2018, In : European Stroke Journal. p. 239698731875669

    Research output: Contribution to journalArticle

  165. Brain structural differences between 73- and 92-year olds matched for childhood intelligence, social background, and intracranial volume

    Ritchie, S. J., Dickie, D. A., Cox, S., Valdes Hernandez, M., Sibbett, R., Pattie, A., Anblagan, D., Redmond, P., Royle, N., Corley, J., Muñoz Maniega, S., Taylor, A., Karama, S., Booth, T., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Feb 2018, In : Neurobiology of Aging. 62, p. 146-158

    Research output: Contribution to journalArticle

  166. Predictors of gait speed and its change over three years in community-dwelling older people

    Pinter, D., Ritchie, S. J., Gattringer, T., Bastin, M., Valdes Hernandez, M., Corley, J., Muñoz Maniega, S., Pattie, A., Dickie, D. A., Gow, A., Starr, J., Deary, I., Enzinger, C., Fazekas, F. & Wardlaw, J., 20 Jan 2018, In : Aging.

    Research output: Contribution to journalArticle

  167. The impact of early life intelligence quotient on post stroke cognitive impairment

    Makin, S., Doubal, F., Shuler, K., Chappell, F., Staals, J., Dennis, M. & Wardlaw, J., 8 Jan 2018, In : European Stroke Journal.

    Research output: Contribution to journalArticle

  168. Coupled changes in hippocampal structure and cognitive ability in later life

    Anblagan, D., Valdes Hernandez, M., Ritchie, S. J., Aribisala, B., Royle, N., Hamilton, I., Cox, S., Gow, A., Pattie, A., Corley, J., Starr, J., Muñoz Maniega, S., Bastin, M., Deary, I. & Wardlaw, J., 4 Jan 2018, In : Brain and Behavior.

    Research output: Contribution to journalArticle

  169. Brain cortical characteristics of lifetime cognitive ageing

    Cox, S., Bastin, M., Ritchie, S. J., Dickie, D. A., Liewald, D., Muñoz Maniega, S., Redmond, P., Royle, N., Pattie, A., Valdes Hernandez, M., Corley, J., Aribisala, B., McIntosh, A., Wardlaw, J. & Deary, I., Jan 2018, In : Brain Structure and Function. 223, 1, p. 509–518

    Research output: Contribution to journalArticle

  170. Brain age predicts mortality

    Cole, J., Ritchie, S. J., Bastin, M., Valdes Hernandez, M., Muñoz Maniega, S., Royle, N., Corley, J., Pattie, A., Harris, S., Zhang, Q., Wray, N. R., Redmond, P., Marioni, R., Starr, J., Cox, S., Wardlaw, J., Sharp, D. & Deary, I., 2018, In : Molecular Psychiatry. 23, p. 1385-1392 8 p.

    Research output: Contribution to journalArticle

  171. White matter hyperintensity and stroke lesion segmentation and differentiation using convolutional neural networks

    Guerrero, R., Qin, C., Oktay, O., Bowles, C., Chen, L., Joules, R., Wolz, R., Valdes Hernandez, M., Dickie, D. A., Wardlaw, J. & Rueckert, D., 2018, In : NeuroImage. 17, p. 918-934

    Research output: Contribution to journalArticle

  172. 2017
  173. Reference Tracts and Generative Models for Brain White Matter Tractography †

    Muñoz Maniega, S., Bastin, M., Deary, I., Wardlaw, J. & Clayden, J., 28 Dec 2017, In : Journal of Imaging . 4, 1, p. 8

    Research output: Contribution to journalArticle

  174. Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data

    Campbell, B. C. V., Van Zwam, W. H., Goyal, M., Menon, B. K., Dippel, D. W. J., Demchuk, A. M., Bracard, S., White, P., Dávalos, A., Majoie, C. B. L. M., Van Der Lugt, A., Ford, G. A., De La Ossa, N. P., Kelly, M., Bourcier, R., Donnan, G. A., Roos, Y. B. W. E. M., Bang, O. Y., Nogueira, R. G., Devlin, T. G. & 1,356 others, Van Den Berg, L. A., Clarençon, F., Burns, P., Carpenter, J., Berkhemer, O. A., Yavagal, D. R., Pereira, V. M., Ducrocq, X., Dixit, A., Quesada, H., Epstein, J., Davis, S. M., Jansen, O., Rubiera, M., Urra, X., Micard, E., Lingsma, H. F., Naggara, O., Brown, S., Guillemin, F., Muir, K. W., Van Oostenbrugge, R. J., Saver, J. L., Jovin, T. G., Hill, M. D., Mitchell, P. J., Berkhemer, O. A., Fransen, P. S., Beumer, D., Van Den Berg, L. A., Lingsma, H. F., Yoo, A. J., Schonewille, W. J., Vos, J. A., Nederkoorn, P. J., Wermer, M. J., Van Walderveen, M. A., Staals, J., Hofmeijer, J., Van Oostayen, J. A., Lycklama À Nijeholt, G. J., Boiten, J., Brouwer, P. A., Emmer, B. J., De Bruijn, S. F., Van Dijk, L. C., Kappelle, J., Lo, R. H., Van Dijk, E. J., De Vries, J., De Kort, P. L. M., Van Rooij, W. J. J., Van Den Berg, J. S. P., Van Hasselt, B. A. A. M., Aerden, L. A. M., Dallinga, R. J., Visser, M. C., Bot, J. C. J., Vroomen, P. C., Eshghi, O., Schreuder, T. H. C. M. L., Heijboer, R. J. J., Keizer, K., Tielbeek, A. V., Den Hertog, H. M., Gerrits, D. G., Van Den Berg-vos, R. M., Karas, G. B., Steyerberg, E. W., Flach, Z., Marquering, H. A., Sprengers, M. E. S., Jenniskens, S. F. M., Beenen, L. F. M., Van Den Berg, R., Koudstaal, P. J., Van Zwam, W. H., Roos, Y. B. W. E. M., Van Der Lugt, A., Van Oostenbrugge, R. J., Majoie, C. B. L. M., Dippel, D. W. J., Brown, M. M., Liebig, T., Stijnen, T., Andersson, T., Mattle, H., Wahlgren, N., Van Der Heijden, E., Ghannouti, N., Fleitour, N., Hooijenga, I., Puppels, C., Pellikaan, W., Geerling, A., Lindl-velema, A., Van Vemde, G., De Ridder, A., Greebe, P., De Bont-stikkelbroeck, J., De Meris, J., Janssen, K., Struijk, W., Licher, S., Boodt, N., Ros, A., Venema, E., Slokkers, I., Ganpat, R., Mulder, M., Saiedie, N., Heshmatollah, A., Schipperen, S., Vinken, S., Van Boxtel, T., Koets, J., Boers, M., Santos, E., Borst, J., Jansen, I., Kappelhof, M., Lucas, M., Geuskens, R., Barros, R. S., Dobbe, R., Csizmadia, M., Hill, M., Goyal, M., Demchuk, A., Menon, B., Eesa, M., Ryckborst, K., Wright, M., Kamal, N., Andersen, L., Randhawa, P., Stewart, T., Patil, S., Minhas, P., Almekhlafi, M., Mishra, S., Clement, F., Sajobi, T., Shuaib, A., Montanera, W., Roy, D., Silver, F., Jovin, T., Frei, D., Sapkota, B., Rempel, J., Thornton, J., Williams, D., Tampieri, D., Poppe, A., Dowlatshahi, D., Wong, J., Mitha, A., Subramaniam, S., Hull, G., Lowerison, M., Sajobi, T., Salluzzi, M., Wright, M., Maxwell, M., Lacusta, S., Drupals, E., Armitage, K., Barber, P., Smith, E., Morrish, W., Coutts, S., Derdeyn, C., Demaerschalk, B., Yavagal, D., Martin, R., Brant, R., Yu, Y., Willinsky, R., Montanera, W., Weill, A., Kenney, C., Aram, H., Stewart, T., Stys, P., Watson, T., Klein, G., Pearson, D., Couillard, P., Trivedi, A., Singh, D., Klourfeld, E., Imoukhuede, O., Nikneshan, D., Blayney, S., Reddy, R., Choi, P., Horton, M., Musuka, T., Dubuc, V., Field, T., Desai, J., Adatia, S., Alseraya, A., Nambiar, V., Van Dijk, R., Wong, J., Mitha, A., Morrish, W., Eesa, M., Newcommon, N., Shuaib, A., Schwindt, B., Butcher, K., Jeerakathil, T., Buck, B., Khan, K., Naik, S., Emery, D., Owen, R., Kotylak, T., Ashforth, R., Yeo, T., Mcnally, D., Siddiqui, M., Saqqur, M., Hussain, D., Kalashyan, H., Manosalva, A., Kate, M., Gioia, L., Hasan, S., Mohammad, A., Muratoglu, M., Williams, D., Thornton, J., Cullen, A., Brennan, P., O'hare, A., Looby, S., Hyland, D., Duff, S., Mccusker, M., Hallinan, B., Lee, S., Mccormack, J., Moore, A., O'connor, M., Donegan, C., Brewer, L., Martin, A., Murphy, S., O'rourke, K., Smyth, S., Kelly, P., Lynch, T., Daly, T., O'brien, P., O'driscoll, A., Martin, M., Daly, T., Collins, R., Coughlan, T., Mccabe, D., Murphy, S., O'neill, D., Mulroy, M., Lynch, O., Walsh, T., O'donnell, M., Galvin, T., Harbison, J., Mcelwaine, P., Mulpeter, K., Mcloughlin, C., Reardon, M., Harkin, E., Dolan, E., Watts, M., Cunningham, N., Fallon, C., Gallagher, S., Cotter, P., Crowe, M., Doyle, R., Noone, I., Lapierre, M., Coté, V., Lanthier, S., Odier, C., Durocher, A., Raymond, J., Weill, A., Daneault, N., Deschaintre, Y., Jankowitz, B., Baxendell, L., Massaro, L., Jackson-graves, C., Decesare, S., Porter, P., Armbruster, K., Adams, A., Billigan, J., Oakley, J., Ducruet, A., Jadhav, A., Giurgiutiu, D., Aghaebrahim, A., Reddy, V., Hammer, M., Starr, M., Totoraitis, V., Wechsler, L., Streib, S., Rangaraju, S., Campbell, D., Rocha, M., Gulati, D., Silver, F., Krings, T., Kalman, L., Cayley, A., Williams, J., Stewart, T., Wiegner, R., Casaubon, L., Jaigobin, C., Del Campo, J., Elamin, E., Schaafsma, J., Willinsky, R., Agid, R., Farb, R., Ter Brugge, K., Sapkoda, B., Baxter, B., Barton, K., Knox, A., Porter, A., Sirelkhatim, A., Devlin, T., Dellinger, C., Pitiyanuvath, N., Patterson, J., Nichols, J., Quarfordt, S., Calvert, J., Hawk, H., Fanale, C., Frei, D., Bitner, A., Novak, A., Huddle, D., Bellon, R., Loy, D., Wagner, J., Chang, I., Lampe, E., Spencer, B., Pratt, R., Bartt, R., Shine, S., Dooley, G., Nguyen, T., Whaley, M., Mccarthy, K., Teitelbaum, J., Tampieri, D., Poon, W., Campbell, N., Cortes, M., Dowlatshahi, D., Lum, C., Shamloul, R., Robert, S., Stotts, G., Shamy, M., Steffenhagen, N., Blacquiere, D., Hogan, M., Alhazzaa, M., Basir, G., Lesiuk, H., Iancu, D., Santos, M., Choe, H., Weisman, D., Jonczak, K., Blue-schaller, A., Shah, Q., Mackenzie, L., Klein, B., Kulandaivel, K., Kozak, O., Gzesh, D., Harris, L., Khoury, J., Mandzia, J., Pelz, D., Crann, S., Fleming, L., Hesser, K., Beauchamp, B., Amato-marzialli, B., Boulton, M., Lopez- Ojeda, P., Sharma, M., Lownie, S., Chan, R., Swartz, R., Howard, P., Golob, D., Gladstone, D., Boyle, K., Boulos, M., Hopyan, J., Yang, V., Da Costa, L., Holmstedt, C., Turk, A., Navarro, R., Jauch, E., Ozark, S., Turner, R., Phillips, S., Shankar, J., Jarrett, J., Gubitz, G., Maloney, W., Vandorpe, R., Schmidt, M., Heidenreich, J., Hunter, G., Kelly, M., Whelan, R., Peeling, L., Burns, P., Hunter, A., Wiggam, I., Kerr, E., Watt, M., Fulton, A., Gordon, P., Rennie, I., Flynn, P., Smyth, G., O'leary, S., Gentile, N., Linares, G., Mcnelis, P., Erkmen, K., Katz, P., Azizi, A., Weaver, M., Jungreis, C., Faro, S., Shah, P., Reimer, H., Kalugdan, V., Saposnik, G., Bharatha, A., Li, Y., Kostyrko, P., Santos, M., Marotta, T., Montanera, W., Sarma, D., Selchen, D., Spears, J., Heo, J., Jeong, K., Kim, D., Kim, B., Kim, Y., Song, D., Lee, K., Yoo, J., Bang, O., Rho, S., Lee, J., Jeon, P., Kim, K., Cha, J., Kim, S., Ryoo, S., Lee, M., Sohn, S., Kim, C., Ryu, H., Hong, J., Chang, H., Lee, C., Rha, J., Davis, S. M., Donnan, G. A., Campbell, B. C., Mitchell, P. J., Churilov, L., Yan, B., Dowling, R., Yassi, N., Oxley, T. J., Wu, T. Y., Silver, G., Mcdonald, A., Mccoy, R., Kleinig, T. J., Scroop, R., Dewey, H. M., Simpson, M., Brooks, M., Coulton, B., Krause, M., Harrington, T. J., Steinfort, B., Faulder, K., Priglinger, M., Day, S., Phan, T., Chong, W., Holt, M., Chandra, R. V., Ma, H., Young, D., Wong, K., Wijeratne, T., Tu, H., Mackay, E., Celestino, S., Bladin, C. F., Loh, P. S., Gilligan, A., Ross, Z., Coote, S., Frost, T., Parsons, M. W., Miteff, F., Levi, C. R., Ang, T., Spratt, N., Kaauwai, L., Badve, M., Rice, H., De Villiers, L., Barber, P. A., Mcguinness, B., Hope, A., Moriarty, M., Bennett, P., Wong, A., Coulthard, A., Lee, A., Jannes, J., Field, D., Sharma, G., Salinas, S., Cowley, E., Snow, B., Kolbe, J., Stark, R., King, J., Macdonnell, R., Attia, J., D'este, C., Saver, J. L., Goyal, M., Diener, H. C., Levy, E. I., Bonafé, A., Mendes Pereira, V., Jahan, R., Albers, G. W., Cognard, C., Cohen, D. J., Hacke, W., Jansen, O., Jovin, T. G., Mattle, H. P., Nogueira, R. G., Siddiqui, A. H., Yavagal, D. R., Von Kummer, R., Smith, W., Turjman, F., Hamilton, S., Chiacchierini, R., Amar, A., Sanossian, N., Loh, Y., Devlin, T., Baxter, B., Hawk, H., Sapkota, B., Quarfordt, S., Sirelkhatim, A., Dellinger, C., Barton, K., Reddy, V., Ducruet, A., Jadhav, A., Horev, A., Giurgiutiu, D., Totoraitis, V., Hammer, M., Jankowitz, B., Wechsler, L., Rocha, M., Gulati, D., Campbell, D., Star, M., Baxendell, L., Oakley, J., Siddiqui, A., Hopkins, L., Snyder, K., Sawyer, R., Hall, S., Costalat, V., Riquelme, C., Machi, P., Omer, E., Arquizan, C., Mourand, I., Charif, M., Ayrignac, X., Menjot De Champfleur, N., Leboucq, N., Gascou, G., Moynier, M., Du Mesnil De Rochemont, R., Singer, O., Berkefeld, J., Foerch, C., Lorenz, M., Pfeilschifer, W., Hattingen, E., Wagner, M., You, S., Lescher, S., Braun, H., Dehkharghani, S., Belagaje, S., Anderson, A., Lima, A., Obideen, M., Haussen, D., Dharia, R., Frankel, M., Patel, V., Owada, K., Saad, A., Amerson, L., Horn, C., Doppelheuer, S., Schindler, K., Lopes, D., Chen, M., Moftakhar, R., Anton, C., Smreczak, M., Carpenter, J., Boo, S., Rai, A., Roberts, T., Tarabishy, A., Gutmann, L., Brooks, C., Brick, J., Domico, J., Reimann, G., Hinrichs, K., Becker, M., Heiss, E., Selle, C., Witteler, A., Al'boutros, S., Danch, M., Ranft, A., Rohde, S., Burg, K., Weimar, C., Zegarac, V., Hartmann, C., Schlamann, M., Göricke, S., Ringlestein, A., Wanke, I., Mönninghoff, C., Dietzold, M., Budzik, R., Davis, T., Eubank, G., Hicks, W., Pema, P., Vora, N., Mejilla, J., Taylor, M., Clark, W., Rontal, A., Fields, J., Peterson, B., Nesbit, G., Lutsep, H., Bozorgchami, H., Priest, R., Ologuntoye, O., Barnwell, S., Dogan, A., Herrick, K., Takahasi, C., Beadell, N., Brown, B., Jamieson, S., Hussain, M., Russman, A., Hui, F., Wisco, D., Uchino, K., Khawaja, Z., Katzan, I., Toth, G., Cheng Ching, E., Bain, M., Man, S., Farrag, A., George, P., John, S., Shankar, L., Drofa, A., Dahlgren, R., Bauer, A., Itreat, A., Taqui, A., Cerejo, R., Richmond, A., Ringleb, P., Bendszus, M., Möhlenbruch, M., Reiff, T., Amiri, H., Purrucker, J., Herweh, C., Pham, M., Menn, O., Ludwig, I., Acosta, I., Villar, C., Morgan, W., Sombutmai, C., Hellinger, F., Allen, E., Bellew, M., Gandhi, R., Bonwit, E., Aly, J., Ecker, R., Seder, D., Morris, J., Skaletsky, M., Belden, J., Baker, C., Connolly, L., Papanagiotou, P., Roth, C., Kastrup, A., Politi, M., Brunner, F., Alexandrou, M., Merdivan, H., Ramsey, C., Given Ii, C., Renfrow, S., Deshmukh, V., Sasadeusz, K., Vincent, F., Thiesing, J., Putnam, J., Bhatt, A., Kansara, A., Caceves, D., Lowenkopf, T., Yanase, L., Zurasky, J., Dancer, S., Freeman, B., Scheibe Mirek, T., Robison, J., Rontal, A., Roll, J., Clark, D., Rodriguez, M., Fitzsimmons, B., Zaidat, O., Lynch, J., Lazzaro, M., Larson, T., Padmore, L., Das, E., Farrow Schmidt, A., Hassan, A., Tekle, W., Cate, C., Jansen, O., Cnyrim, C., Wodarg, F., Wiese, C., Binder, A., Riedel, C., Rohr, A., Lang, N., Laufs, H., Krieter, S., Remonda, L., Diepers, M., Añon, J., Nedeltchev, K., Kahles, T., Biethahn, S., Lindner, M., Chang, V., Gächter, C., Esperon, C., Guglielmetti, M., Arenillas Lara, J., Martínez Galdámez, M., Calleja Sanz, A., Cortijo Garcia, E., Garcia Bermejo, P., Perez, S., Mulero Carrillo, P., Crespo Vallejo, E., Ruiz Piñero, M., Lopez Mesonero, L., Reyes Muñoz, F., Brekenfeld, C., Buhk, J., Kruützelmann, A., Thomalla, G., Cheng, B., Beck, C., Hoppe, J., Goebell, E., Holst, B., Grzyska, U., Wortmann, G., Starkman, S., Duckwiler, G., Jahan, R., Rao, N., Sheth, S., Ng, K., Noorian, A., Szeder, V., Nour, M., Mcmanus, M., Huang, J., Tarpley, J., Tateshima, S., Gonzalez, N., Ali, L., Liebeskind, D., Hinman, J., Calderon Arnulphi, M., Liang, C., Guzy, J., Koch, S., Desousa, K., Gordon Perue, G., Haussen, D., Elhammady, M., Peterson, E., Pandey, V., Dharmadhikari, S., Khandelwal, P., Malik, A., Pafford, R., Gonzalez, P., Ramdas, K., Andersen, G., Damgaard, D., Von Weitzel Mudersbach, P., Simonsen, C., Ruiz De Morales Ayudarte, N., Poulsen, M., Sørensen, L., Karabegovich, S., Hjørringgaard, M., Hjort, N., Harbo, T., Sørensen, K., Deshaies, E., Padalino, D., Swarnkar, A., Latorre, J., Elnour, E., El Zammar, Z., Villwock, M., Farid, H., Balgude, A., Cross, L., Hansen, K., Holtmannspötter, M., Kondziella, D., Hoejgaard, J., Taudorf, S., Soendergaard, H., Wagner, A., Cronquist, M., Stavngaard, T., Cortsen, M., Krarup, L., Hyldal, T., Haring, H., Guggenberger, S., Hamberger, M., Trenkler, J., Sonnberger, M., Nussbaumer, K., Dominger, C., Bach, E., Jagadeesan, B., Taylor, R., Kim, J., Shea, K., Tummala, R., Zacharatos, H., Sandhu, D., Ezzeddine, M., Grande, A., Hildebrandt, D., Miller, K., Scherber, J., Hendrickson, A., Jumaa, M., Zaidi, S., Hendrickson, T., Snyder, V., Killer Oberpfalzer, M., Mutzenbach, J., Weymayr, F., Broussalis, E., Stadler, K., Jedlitschka, A., Malek, A., Mueller Kronast, N., Beck, P., Martin, C., Summers, D., Day, J., Bettinger, I., Holloway, W., Olds, K., Arkin, S., Akhtar, N., Boutwell, C., Crandall, S., Schwartzman, M., Weinstein, C., Brion, B., Prothmann, S., Kleine, J., Kreiser, K., Boeckh Behrens, T., Poppert, H., Wunderlich, S., Koch, M., Biberacher, V., Huberle, A., Gora Stahlberg, G., Knier, B., Meindl, T., Utpadel Fischler, D., Zech, M., Kowarik, M., Seifert, C., Schwaiger, B., Puri, A., Hou, S., Wakhloo, A., Moonis, M., Henniger, N., Goddeau, R., Massari, F., Minaeian, A., Lozano, J., Ramzan, M., Stout, C., Patel, A., Tunguturi, A., Onteddu, S., Carandang, R., Howk, M., Ribó, M., Sanjuan, E., Rubiera, M., Pagola, J., Flores, A., Muchada, M., Meler, P., Huerga, E., Gelabert, S., Coscojuela, P., Tomasello, A., Rodriguez, D., Santamarina, E., Maisterra, O., Boned, S., Seró, L., Rovira, A., Molina, C., Millán, M., Muñoz, L., Pérez De La Ossa, N., Gomis, M., Dorado, L., López-cancio, E., Palomeras, E., Munuera, J., García Bermejo, P., Remollo, S., Castaño, C., García-sort, R., Cuadras, P., Puyalto, P., Hernández-pérez, M., Jiménez, M., Martínez-piñeiro, A., Lucente, G., Dávalos, A., Chamorro, A., Urra, X., Obach, V., Cervera, A., Amaro, S., Llull, L., Codas, J., Balasa, M., Navarro, J., Ariño, H., Aceituno, A., Rudilosso, S., Renu, A., Macho, J., San Roman, L., Blasco, J., López, A., Macías, N., Cardona, P., Quesada, H., Rubio, F., Cano, L., Lara, B., De Miquel, M., Aja, L., Serena, J., Cobo, E., Albers, G. W., Lees, K. R., Arenillas, J., Roberts, R., Minhas, P., Al-ajlan, F., Salluzzi, M., Zimmel, L., Patel, S., Eesa, M., Martí-fàbregas, J., Jankowitz, B., Serena, J., Salvat-plana, M., López-cancio, E., Bracard, S., Ducrocq, X., Anxionnat, R., Baillot, P., Barbier, C., Derelle, A., Lacour, J., Richard, S., Samson, Y., Sourour, N., Baronnet-chauvet, F., Clarencon, F., Crozier, S., Deltour, S., Di Maria, F., Le Bouc, R., Leger, A., Mutlu, G., Rosso, C., Szatmary, Z., Yger, M., Zavanone, C., Bakchine, S., Pierot, L., Caucheteux, N., Estrade, L., Kadziolka, K., Leautaud, A., Renkes, C., Serre, I., Desal, H., Guillon, B., Boutoleau-bretonniere, C., Daumas-duport, B., De Gaalon, S., Derkinderen, P., Evain, S., Herisson, F., Laplaud, D., Lebouvier, T., Lintia-gaultier, A., Pouclet-courtemanche, H., Rouaud, T., Rouaud Jaffrenou, V., Schunck, A., Sevin-allouet, M., Toulgoat, F., Wiertlewski, S., Gauvrit, J., Ronziere, T., Cahagne, V., Ferre, J., Pinel, J., Raoult, H., Mas, J., Meder, J., Al Najjar-carpentier, A., Birchenall, J., Bodiguel, E., Calvet, D., Domigo, V., Godon-hardy, S., Guiraud, V., Lamy, C., Majhadi, L., Morin, L., Naggara, O., Trystram, D., Turc, G., Berge, J., Sibon, I., Menegon, P., Barreau, X., Rouanet, F., Debruxelles, S., Kazadi, A., Renou, P., Fleury, O., Pasco-papon, A., Dubas, F., Caroff, J., Godard Ducceschi, S., Hamon, M., Lecluse, A., Marc, G., Giroud, M., Ricolfi, F., Bejot, Y., Chavent, A., Gentil, A., Kazemi, A., Osseby, G., Voguet, C., Mahagne, M., Sedat, J., Chau, Y., Suissa, L., Lachaud, S., Houdart, E., Stapf, C., Buffon Porcher, F., Chabriat, H., Guedin, P., Herve, D., Jouvent, E., Mawet, J., Saint-maurice, J., Schneble, H., Turjman, F., Nighoghossian, N., Berhoune, N., Bouhour, F., Cho, T., Derex, L., Felix, S., Gervais-bernard, H., Gory, B., Manera, L., Mechtouff, L., Ritzenthaler, T., Riva, R., Salaris Silvio, F., Tilikete, C., Blanc, R., Obadia, M., Bartolini, M. B., Gueguen, A., Piotin, M., Pistocchi, S., Redjem, H., Drouineau, J., Neau, J., Godeneche, G., Lamy, M., Marsac, E., Velasco, S., Clavelou, P., Chabert, E., Bourgois, N., Cornut-chauvinc, C., Ferrier, A., Gabrillargues, J., Jean, B., Marques, A., Vitello, N., Detante, O., Barbieux, M., Boubagra, K., Favre Wiki, I., Garambois, K., Tahon, F., Ashok, V., Voguet, C., Coskun, O., Guedin, P., Rodesch, G., Lapergue, B., Bourdain, F., Evrard, S., Graveleau, P., Decroix, J. P., Wang, A., Sellal, F., Ahle, G., Carelli, G., Dugay, M., Gaultier, C., Lebedinsky, A. P., Lita, L., Musacchio, R. M., Renglewicz-destuynder, C., Tournade, A., Vuillemet, F., Montoro, F. M., Mounayer, C., Faugeras, F., Gimenez, L., Labach, C., Lautrette, G., Denier, C., Saliou, G., Chassin, O., Dussaule, C., Melki, E., Ozanne, A., Puccinelli, F., Sachet, M., Sarov, M., Bonneville, J., Moulin, T., Biondi, A., De Bustos Medeiros, E., Vuillier, F., Courtheoux, P., Viader, F., Apoil-brissard, M., Bataille, M., Bonnet, A., Cogez, J., Kazemi, A., Touze, E., Leclerc, X., Leys, D., Aggour, M., Aguettaz, P., Bodenant, M., Cordonnier, C., Deplanque, D., Girot, M., Henon, H., Kalsoum, E., Lucas, C., Pruvo, J., Zuniga, P., Bonafé, A., Arquizan, C., Costalat, V., Machi, P., Mourand, I., Riquelme, C., Bounolleau, P., Arteaga, C., Faivre, A., Bintner, M., Tournebize, P., Charlin, C., Darcel, F., Gauthier-lasalarie, P., Jeremenko, M., Mouton, S., Zerlauth, J., Lamy, C., Hervé, D., Hassan, H., Gaston, A., Barral, F., Garnier, P., Beaujeux, R., Wolff, V., Herbreteau, D., Debiais, S., Murray, A., Ford, G., Muir, K. W., White, P., Brown, M. M., Clifton, A., Freeman, J., Ford, I., Markus, H., Wardlaw, J., Lees, K. R., Molyneux, A., Robinson, T., Lewis, S., Norrie, J., Robertson, F., Perry, R., Dixit, A., Cloud, G., Clifton, A., Madigan, J., Roffe, C., Nayak, S., Lobotesis, K., Smith, C., Herwadkar, A., Kandasamy, N., Goddard, T., Bamford, J., Subramanian, G., Lenthall, R., Littleton, E., Lamin, S., Storey, K., Ghatala, R., Banaras, A., Aeron-thomas, J., Hazel, B., Maguire, H., Veraque, E., Harrison, L., Keshvara, R. & Cunningham, J., 16 Dec 2017, In : Lancet Neurology. 17, 1, p. 47-53

    Research output: Contribution to journalArticle

  175. Deep Learning vs. Conventional Machine Learning: Pilot Study of WMH Segmentation in Brain MRI with Absence or Mild Vascular Pathology

    Rachmadi, M., Valdes Hernandez, M., Agan, M. L. F., Komura, T. & Alzheimer’s Disease Neuroimaging Initiative, 14 Dec 2017, In : Journal of Imaging .

    Research output: Contribution to journalArticle

  176. Intracranial pulsatility in patients with cerebral small vessel disease: a systematic review

    Shi, Y., Thrippleton, M., Marshall, I. & Wardlaw, J., 11 Dec 2017, In : Clinical science.

    Research output: Contribution to journalArticle

  177. Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials

    Hacke, W., Lyden, P., Emberson, J., Baigent, C., Blackwell, L., Albers, G. W., Bluhmki, E., Brott, T. G., Cohen, G. R., Davis, S. M., Donnan, G. A., Grotta, J. C., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Olivot, J. M., Parsons, M. & 8 others, Sandercock, P., Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., Whiteley, W., del Zoppo, G. J. & Lees, K. R., 24 Nov 2017, In : International Journal of Stroke.

    Research output: Contribution to journalArticle

  178. Relationship between race and outcome in Asian, Black, and Caucasian patients with spontaneous intracerebral hemorrhage: Data from the Virtual International Stroke Trials Archive and Efficacy of Nitric Oxide in Stroke trial

    Krishnan, K., Beishon, L., Berge, E., Christensen, H., Dineen, R. A., Ozturk, S., Sprigg, N., Wardlaw, J. M. & Bath, P. M., 22 Nov 2017, In : International Journal of Stroke. p. 174749301774446

    Research output: Contribution to journalArticle

  179. Dietary iodine exposure and brain structures and cognition in older people. Exploratory analysis in the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Kyle, J., Allan, J., Allerhand, M., Clark, H., Muñoz Maniega, S., Royle, N., Gow, A., Pattie, A., Corley, J., Bastin, M., Starr, J., Wardlaw, J., Deary, I. & Combet, E., Nov 2017, In : The Journal of Nutrition, Health & Aging. 21, 9, p. 971-979

    Research output: Contribution to journalArticle

  180. Risk and protective factors for structural brain ageing in the eighth decade of life

    Ritchie, S. J., Tucker-Drob, E. M., Cox, S., Dickie, D. A., Valdes Hernandez, M., Corley, J., Royle, N., Redmond, P., Muñoz Maniega, S., Pattie, A., Aribisala, B., Taylor, A., Clarke, T-K., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Nov 2017, In : Brain Structure and Function. 222, 8, p. 1-14 14 p.

    Research output: Contribution to journalArticle

  181. Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability

    ENIGMA Consortium, 20 Oct 2017, In : Nature Communications.

    Research output: Contribution to journalArticle

  182. Optimizing the Definitions of Stroke, TIA and Infarction for Research and Application in Clinical Practice

    Abbott, A. L., Silvestrini, M., Topakian, R., Golledge, J., Brunser, A., de Borst, G. J., Harbaugh, R. E., Doubal, F., Rundek, T., Thapar, A., Davies, A. H., Kam, A. & Wardlaw, J., 18 Oct 2017, In : Frontiers in Neurology.

    Research output: Contribution to journalArticle

  183. Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis

    Duncombe, J., Lennen, R. J., Jansen, M. A., Marshall, I., Wardlaw, J. M. & Horsburgh, K., Oct 2017, In : Neuropathology and Applied Neurobiology. 43, 6

    Research output: Contribution to journalArticle

  184. Cerebrovascular reactivity measurement in cerebral small vessel disease: rationale and reproducibility of a protocol for MRI acquisition and image processing

    Thrippleton, M., Shi, Y., Blair, G., Hamilton, I., Waiter, G. D., Schwarzbauer, C., Pernet, C. R., Andrews, P., Marshall, I., Doubal, F. & Wardlaw, J., 21 Sep 2017, In : International Journal of Stroke.

    Research output: Contribution to journalArticle

  185. Retinal Biomarker Discovery for Dementia in an Elderly Diabetic Population

    VAMPIRE project, Vascular Assessment and Measurement Platform for Images of the REtina, 9 Sep 2017, International Workshop on Ophthalmic Medical Image Analysis. Springer, p. 150-158 (LNCS; vol. 10554).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  186. Small vessel disease and dietary salt intake: cross sectional study and systematic review

    Makin, S., Mubki, G. F., Doubal, F., Shuler, K., Staals, J., Dennis, M. & Wardlaw, J., 8 Sep 2017, In : Journal of Stroke and Cerebrovascular Diseases.

    Research output: Contribution to journalArticle

  187. Blood pressure variability and leukoaraiosis in acute ischemic stroke

    Dickie, D. A., Aribisala, B., Mair, G., Berge, E., Lindley, R. I., Sandercock, P., von Kummer, R., von Heijne, A., Peeters, A., Cala, L., Farrall, A., Morris, Z., Bradey, N., Potter, G., Adami, A. & Wardlaw, J., 5 Sep 2017, In : International Journal of Stroke.

    Research output: Contribution to journalArticle

  188. Maximising the Potential of Longitudinal Cohorts for Research in Neurodegenerative Diseases: A Community Perspective

    Moody, C., Mitchell, D., Kiser, G., Aarsland, D., Berg, D., Brayne, C., Costa, A., Arfan Ikram, M., Mountain, G., Rohrer, J. D., Teunissen, C., van den Berg, L. H. & Wardlaw, J., 29 Aug 2017, In : Frontiers in Neuroscience.

    Research output: Contribution to journalArticle

  189. White matter hyperintensity reduction and outcomes after minor stroke

    Wardlaw, J., Chappell, F. M., Valdes Hernandez, M., Makin, S., Staals, J., Shuler, K., Thrippleton, M., Armitage, P., Muñoz Maniega, S., Heye, A., Sakka, E. & Dennis, M., 9 Aug 2017, In : Neurology.

    Research output: Contribution to journalArticle

  190. Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)

    Appleton, J. P., Scutt, P., Dixon, M., Howard, H., Haywood, L., Havard, D., Hepburn, T., England, T., Sprigg, N., Woodhouse, L. J., Wardlaw, J. M., Montgomery, A. A., Pocock, S., Bath, P. M. & RIGHT-2 Investigators, 1 Aug 2017, In : International Journal of Stroke. p. 1747493017724627

    Research output: Contribution to journalArticle

  191. Infections up to 76 days after stroke increase disability and death

    Learoyd, A. E., Woodhouse, L., Shaw, L., Sprigg, N., Bereczki, D., Berge, E., Caso, V., Christensen, H., Collins, R., Czlonkowska, A., El Etribi, A., Farr, T. D., Gommans, J., Laska, A. C., Ntaios, G., Ozturk, S., Pocock, S. J., Prasad, K., Wardlaw, J., Fone, K. & 2 others, Bath, P. M. & Trueman, R. C., 27 Jul 2017, In : Translational Stroke Research.

    Research output: Contribution to journalArticle

  192. Detection, risk factors, and functional consequences of cerebral microinfarcts

    van Veluw, S. J., Shih, A. Y., Smith, E. E., Chen, C., Schneider, J. A., Wardlaw, J., Greenberg, S. M. & Biessels, G. J., 14 Jul 2017, In : Lancet Neurology.

    Research output: Contribution to journalArticle

  193. Education, socioeconomic status, and intelligence in childhood and stroke risk in later life: A Meta-analysis

    McHutchison, C., Backhouse, E., Cvoro, V., Shenkin, S. & Wardlaw, J., Jul 2017, In : Epidemiology. 28, 4

    Research output: Contribution to journalArticle

  194. Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 Study

    McGrory, S., Taylor, A., Kirin, M., Corley, J., Pattie, A., Cox, S., Dhillon, B., Wardlaw, J., Doubal, F., Starr, J., Trucco, E., MacGillivray, T. & Deary, I., Jul 2017, In : British Journal of Ophthalmology. 101, 7, p. 993-998

    Research output: Contribution to journalArticle

  195. Small vessel disease and clinical outcomes after IV rt-PA treatment

    Arba, F., Inzitari, D., Ali, M., Warach, S. J., Luby, M., Lees, K. R., Albers, G. W., Davis, S. M., Donnan, G. A., Fisher, M., Furlan, A. J., Grotta, J. C., Hacke, W., Kang, D. W., Kidwell, C., Koroshetz, W. J., Lev, M. H., Liebeskind, D. S., Gregory Sorensen, A., Thijs, V. N. & 3 others, Thomalla, G., Wardlaw, J. M. & Wintermark, M., Jul 2017, In : Acta neurologica Scandinavica. 136, 1, p. 72-77 6 p.

    Research output: Contribution to journalArticle

  196. Evaluation of Four Supervised Learning Schemes in White Matter Hyperintensities Segmentation in Absence or Mild Presence of Vascular Pathology

    Rachmadi, M., Komura, T., Valdes Hernandez, M. & Agan, M., 22 Jun 2017, Medical Image Understanding and Analysis (MIUA 2017). Springer, Cham, p. 482-493 12 p. (Communications in Computer and Information Science; vol. 723).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  197. Improved reference tracts for unsupervised brain white matter tractography

    Muñoz Maniega, S., Bastin, M., Deary, I., Wardlaw, J. & Clayden, J. D., 22 Jun 2017, Medical Image Understanding and Analysis: 21st Annual Conference, MIUA 2017, Edinburgh, UK, July 11–13, 2017, Proceedings. p. 425-435 (Communications in Computer and Information Science).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  198. Super Resolution Convolutional Neural Networks for Increasing Spatial Resolution of 1H Magnetic Resonance Spectroscopic Imaging

    Cengiz, S., Valdes Hernandez, M. & Ozturk-Isik, E., 22 Jun 2017, Medical Image Understanding and Analysis: 21st Annual Conference, MIUA 2017, Edinburgh, UK, July 11–13, 2017, Proceedings.. p. 641-650 (Communications in Computer and Information Science).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  199. Advanced neuroimaging of cerebral small vessel disease

    Blair, G., Valdes Hernandez, M., Thrippleton, M., Doubal, F. & Wardlaw, J., 15 Jun 2017, In : Current Treatment Options in Cardiovascular Medicine.

    Research output: Contribution to journalArticle

  200. Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73-76

    Cox, S., Ritchie, S. J., Dickie, D. A., Pattie, A., Royle, N., Corley, J., Aribisala, B., Harris, S., Valdes Hernandez, M., Gow, A., Muñoz Maniega, S., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Jun 2017, In : Neurobiology of Aging. 54, p. 54-58

    Research output: Contribution to journalArticle

  201. Molecular genetic contributions to self-rated health

    Harris, S. E., Hagenaars, S. P., Davies, G., Hill, W. D., Liewald, D. CM., Ritchie, S. J., Marioni, R. E., Sudlow, C. LM., Wardlaw, J. M., McIntosh, A. M., Gale, C. R., Deary, I. J., METASTROKE consortium, International Consortium for Blood Pressure, CHARGE consortium Aging and Longevity Group & CHARGE consortium Cognitive Group, Jun 2017, In : International Journal of Epidemiology. 46, 3, p. 994-1009

    Research output: Contribution to journalArticle

  202. Continuing or Temporarily Stopping Pre-Stroke Antihypertensive Medication in Acute Stroke: An Individual Patient Data Meta-Analysis

    Woodhouse, L. J., Manning, L., Potter, J. F., Berge, E., Sprigg, N., Wardlaw, J., Lees, K. R., Bath, P. M., Robinson, T. G. & Blood Pressure in Acute Stroke Collaboration, May 2017, In : Hypertension. 69, 5, p. 933-+ 28 p.

    Research output: Contribution to journalArticle

  203. Fatigue and cognitive function in systemic lupus erythematosus: associations with white matter microstructural damage. A diffusion tensor MRI study and meta-analysis

    Wiseman, S., Bastin, M., Hamilton, I., Hunt, D., Ritchie, S. J., Amft, N., Thomson, S., Belch, J. F. F., Ralston, S. & Wardlaw, J., May 2017, In : Lupus. 26, 6, p. 588-597

    Research output: Contribution to journalArticle

  204. Lateral thinking – interocular symmetry and asymmetry in neurovascular patterning, in health and disease

    Cameron, J., Megaw, R., Tatham, A., McGrory, S., MacGillivray, T., Doubal, F., Wardlaw, J., Trucco, E., Chandran, S. & Dhillon, B., 28 Apr 2017, In : Progress in Retinal and Eye Research.

    Research output: Contribution to journalArticle

  205. Detection of interferon alpha protein reveals differential levels and cellular sources in disease

    Rodero, M. P., Decalf, J., Bondet, V., Hunt, D., Rice, G. I., Werneke, S., McGlasson, S. L., Alyanakian, M-A., Bader-Meunier, B., Barnerias, C., Bellon, N., Belot, A., Bodemer, C., Briggs, T. A., Desguerre, I., Frémond, M-L., Hully, M., van den Maagdenberg, A. MJM., Melki, I., Meyts, I. & 15 others, Musset, L., Pelzer, N., Quartier, P., Terwindt, G. M., Wardlaw, J., Wiseman, S., Rieux-Laucat, F., Rose, Y., Neven, B., Hertel, C., Hayday, A., Albert, M. L., Rozenberg, F., Crow, Y. J. & Duffy, D., 18 Apr 2017, In : Journal of Experimental Medicine.

    Research output: Contribution to journalArticle

  206. Big data and data repurposing - using existing data to answer new questions in vascular dementia research

    Doubal, F. N., Ali, M., Batty, G. D., Charidimou, A., Eriksdotter, M., Hofmann-Apitius, M., Kim, Y-H., Levine, D. A., Mead, G., Mucke, H. A. M., Ritchie, C. W., Roberts, C. J., Russ, T. C., Stewart, R., Whiteley, W. & Quinn, T. J., 17 Apr 2017, In : Bmc neurology. 17, 1, p. 72

    Research output: Contribution to journalArticle

  207. Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Cox, S., Kim, J., Royle, N., Muñoz Maniega, S., Gow, A., Anblagan, D., Bastin, M., Park, J., Starr, J., Wardlaw, J. & Deary, I., Apr 2017, In : Neurobiology of Aging. 52, p. 1-11 11 p.

    Research output: Contribution to journalArticle

  208. Cerebral white matter hypoperfusion increases with small vessel disease burden. Data from the IST-3 trial

    Arba, F., Mair, G., Carpenter, T., Sakka, E., Sandercock, P., Lindley, R., Inzitari, D. & Wardlaw, J., 15 Mar 2017, In : Journal of Stroke and Cerebrovascular Diseases.

    Research output: Contribution to journalArticle

  209. Penumbra and re-canalization acute computed tomography in ischemic stroke evaluation: PRACTISE study protocol

    El Tawil, S., Wardlaw, J., Ford, I., Mair, G., Robinson, T., Kalra, L. & Muir, K. W., 14 Mar 2017, In : International Journal of Stroke.

    Research output: Contribution to journalArticle

  210. Critical Analysis of NeuroAnatomical Software Protocols Reveals Clinically Relevant Differences in Parcellation Schemes

    Mikhael, S., Hoogendoorn, C., Valdes Hernandez, M. & Pernet, C. R., 7 Mar 2017, In : NeuroImage.

    Research output: Contribution to journalArticle

  211. Workshop on Reconstruction Schemes for MR data: Summary of Findings and Recommendations

    Ozturk-Isik, E., Marshall, I., Filipiak, P., Guerra Ones, V., Benjamin, A. J. V., Ortiz Ramón, R. & Valdes Hernandez, M., 15 Feb 2017, In : Royal Society Open Science.

    Research output: Contribution to journalArticle

  212. Improving data availability for brain image biobanking in healthy subjects: practice-based suggestions from an international multidisciplinary working group

    Shenkin, S. D., Pernet, C., Nichols, T. E., Poline, J. B., Matthews, P. M., van der Lugt, A., Mackay, C. E., Lanyon, L. J., Mazoyer, B., Boardman, J. P., Thompson, P. M., Fox, N. C., Marcus, D. S., Sheikh, A., Cox, S. R., Anblagan, D., Job, D. E., Dickie, D. A., Rodriguez, D. & Wardlaw, J. M., 14 Feb 2017, In : NeuroImage.

    Research output: Contribution to journalArticle

  213. Early life risk factors for cerebrovascular disease: A systematic review and meta-analysis

    Backhouse, E. V., McHutchison, C. A., Cvoro, V., Shenkin, S. D. & Wardlaw, J. M., 10 Feb 2017, In : Neurology.

    Research output: Contribution to journalArticle

  214. Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke

    Mair, G., von Kummer, R., Adami, A., White, P. M., Adams, M. E., Yan, B., Demchuk, A. M., Farrall, A. J., Sellar, R. J., Sakka, E., Palmer, J., Perry, D., Lindley, R. I., Sandercock, P. A. G., Wardlaw, J. M. & IST-3 Collaborative Group, 1 Feb 2017, In : Stroke. 48, 2, p. 353-360

    Research output: Contribution to journalArticle

  215. Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort

    Luciano, M., Corley, J., Cox, S., Valdes Hernandez, M., Craig, L., Dickie, D. A., Karama, S., Mcneill, G., Bastin, M., Wardlaw, J. & Deary, I., 31 Jan 2017, In : Neurology. 88, 5, p. 449-455

    Research output: Contribution to journalArticle

  216. Impact of small vessel disease in the brain on gait and balance

    Pinter, D., Ritchie, S. J., Doubal, F., Gattringer, T., Morris, Z., Bastin, M., Valdes Hernandez, M., Royle, N., Corley, J., Muñoz Maniega, S., Pattie, A., Dickie, D. A., Staals, J., Gow, A., Starr, J., Deary, I., Enzinger, C., Fazekas, F. & Wardlaw, J., 30 Jan 2017, In : Scientific Reports. 7, 41637.

    Research output: Contribution to journalArticle

  217. Novel genetic loci associated with hippocampal volume

    Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., Mckay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C., Cichon, S., Cookson, M. R., Corvin, A., Crespo-facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack Jr, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J., Mattay, V. S., Mcdonald, C., Mcintosh, A. M., Mcmahon, F. J., Mcmahon, K. L., Mecocci, P., Melle, I., Meyer-lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Valdes Hernandez, M., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van ’t Ent, D., Van Tol, M., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., 18 Jan 2017, In : Nature Communications. 8, 13624.

    Research output: Contribution to journalArticle

  218. Intensive versus guideline blood pressure and lipid lowering in patients with previous stroke: main results from the pilot ‘Prevention Of Decline in Cognition After Stroke Trial’ (PODCAST) randomised controlled trial

    Bath, P. M., Scutt, P., Blackburn, D. J., Ankolekar, S., Krishnan, K., Ballard, C., Burns, A., Mant, J., Passmore, P. A., Pocock, S. J., Reckless, J., Sprigg, N., Stewart, R., Wardlaw, J. & Ford, G. A., 17 Jan 2017, In : PLoS ONE. 12, 1, e0164608.

    Research output: Contribution to journalArticle

  219. Whole brain magnetic resonance image atlases: a systematic review of existing atlases and caveats for use in population imaging

    Dickie, D., Shenkin, S., Anblagan, D., Lee, J. Y., Blesa Cabez, M., Rodriguez, D., Boardman, J., Waldman, A., Job, D. & Wardlaw, J., 4 Jan 2017, In : Frontiers in Neuroinformatics. 11, p. 1 1 p.

    Research output: Contribution to journalArticle

  220. 21st Annual Conference on Medical Image Understanding and Analysis, MIUA 2017

    Valdes Hernandez, M. (ed.) & Gonzalez-Castro, V. (ed.), 2017, Medical Image Understanding and Analysis - 21st Annual Conference, MIUA 2017, Proceedings. Springer-Verlag, Vol. 723. p. 1-949 949 p. (Communications in Computer and Information Science; vol. 723).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  221. A Robust Matlab Tool for Gyral Measurements

    Mikhael, S., Gray, C. D., MacGillivray, T. J., Valdés Hernández, M., Hoogendoorn, C. & Pernet, C., 2017, Organization for Human Brain Mapping (OHBM) Annual Meeting. Vancouver

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  222. A Standalone and Robust Matlab Tool for Gyral Measurements

    Mikhael, S., Gray, C. D., MacGillivray, T. J., Valdés Hernández, M., Hoogendoorn, C. & Pernet, C., 2017, SINAPSE Annual Scientific Meeting. Glasgow

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  223. Brain Lesion Segmentation through Image Synthesis and Outlier Detection

    Bowles, C., Qin, C., Guerrero, R., Gunn, R., Hammers, A., Dickie, D. A., Valdes Hernandez, M., Wardlaw, J. & Rueckert, D., 2017, In : NeuroImage: Clinical. 16, p. 643-658

    Research output: Contribution to journalArticle

  224. Selected Papers from MIUA 2017

    Valdes Hernandez, M. (ed.) & Gonzalez- Castro, V. (ed.), 2017, In : Journal of Imaging .

    Research output: Contribution to journalSpecial issue

  225. The application of retinal fundus camera imaging in dementia: a systematic review

    McGrory, S., Cameron, J., Pellegrini, E., Warren, C., Doubal, F., Deary, I., Dhillon, B., Wardlaw, J., Trucco, E. & MacGillivray, T., 2017, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 6, p. 91-107

    Research output: Contribution to journalArticle

  226. 2016
  227. Developing an integrated image bank and metadata for large scale research in cerebrovascular disease: our experience from the Stroke Image Bank Project

    Danso, S., Wardlaw, J., Sandercock, P., Job, D., Dickie, D. A., Rodriguez Gonzalez, D., Palmer, J. & Bath, P., 26 Dec 2016, In : Frontiers in ICT. 3, 32.

    Research output: Contribution to journalArticle

  228. Ageing and brain white matter structure in 3513 UK Biobank participants

    Cox, S., Ritchie, S. J., Tucker-Drob, E. M., Liewald, D., Hagenaars, S., Davies, G., Wardlaw, J., Gale, C., Bastin, M. & Deary, I., 15 Dec 2016, In : Nature Communications. 7, p. 1-13 13 p., 13629.

    Research output: Contribution to journalArticle

  229. Carotid disease at age 73 and cognitive change from age 70 to 76 years. A longitudinal cohort study

    Wardlaw, J., Allerhand, M., Eadie, E., Thomas, A., Corley, J., Pattie, A., Taylor, A., Shenkin, S., Cox, S., Gow, A., Starr, J. & Deary, I., 14 Dec 2016, In : Journal of Cerebral Blood Flow and Metabolism. p. 271678X16683693

    Research output: Contribution to journalArticle

  230. Frequency and predictors of dysphagia in patients with recent small subcortical infarcts

    Fandler, S., Gattringer, T., Eppinger, S., Doppelhofer, K., Pinter, D., Niederkorn, K., Enzinger, C., Wardlaw, J. & Fazekas, F., 6 Dec 2016, In : Stroke.

    Research output: Contribution to journalArticle

  231. Mortality after thrombolysis – Authors’ reply

    Berge, E., Cohen, G. R., Whiteley, W., Wardlaw, J. & Sandercock, P., 1 Dec 2016, In : Lancet Neurology.

    Research output: Contribution to journalComment/debate

  232. Effect of Right Insular Involvement on Death and Functional Outcome after Acute Ischemic Stroke in the IST-3 Trial

    Sposato, L. A., Cohen, G., Wardlaw, J. M., Sandercock, P., Lindley, R. I., Hachinski, V., IST-3 Expert Reading Panel & IST-3 Collaborative Grp, Dec 2016, In : Stroke. 47, 12, p. 2959-2965 7 p.

    Research output: Contribution to journalArticle

  233. Endothelial function, inflammation, thrombosis and basal ganglia perivascular spaces in patients with stroke

    Wang, X., Chappell, F., Valdes Hernandez, M., Lowe, G. D. O., Rumley, A., Shuler, K., Doubal, F. & Wardlaw, J., Dec 2016, In : Journal of Stroke and Cerebrovascular Diseases. 25, 12

    Research output: Contribution to journalArticle

  234. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

    Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S-J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L-P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., Smith, A. V. & 31 others, Vojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y-D. I., Cupples, L. A., de Jong, P. A., de Koning, H., de Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Wardlaw, J. M., Deary, I. J., Wilson, J. G. & CHARGE Consortium, 21 Nov 2016, In : Circulation. Cardiovascular genetics.

    Research output: Contribution to journalArticle

  235. STROKOG (Stroke and Cognition consortium): An international consortium to examine the epidemiology, diagnosis and treatment of neurocognitive disorders in relation to cerebrovascular disease

    Sachdev, P. S., Lo, J. W., Crawford, J., Mellon, L., Hickey, A., Williams, D., Bordet, R., Mendyk, A-M., Gelé, P., Deplanque, D., Bae, H-J., Lim, J-S., Brodtmann, A., Werden, E., Cumming, T., Köhler, S., Verhey, F. R. J., Dong, Y-H., Tan, H. H., Chen, C. & 46 others, Kalaria, R. N., Allan, L. M., Akinyemi, R. O., Ogunniyi, A., Klimkowicz-Mrowiec, A., Dichgans, M., Wollenweber, F. A., Zietemann, V., Hoffmann, M., Desmond, D. W., Linden, T., Blomstrand, C., Fagerberg, B., Skoog, I., Godefroy, O., Barbay, M., Roussel, M., Lee, B-C., Yu, K-H., Wardlaw, J., Makin, S., Doubal, F., Chappell, F., Srikanth, V., Thrift, A. G., Donnan, G. A., Kandiah, N., Chander, R. J., Lin, X., Cordonnier, C., Moulin, S., Rossi, C., Sabayan, B., Stott, D. J., Jukema, J. W., Melkas, S., Jokinen, H., Erkinjuntti, T., Mok, V. C. T., Wong, A., Lam, B. Y. K., Leys, D., Hénon, H., Bombois, S., Lipnicki, D. M. & Kochan, N. A., 18 Nov 2016, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticle

  236. Inter-hemispheric characterisation of small vessel disease imaging markers after subcortical infarct

    Valdes Hernandez, M., Qiu, X., Wang, X., Wiseman, S., Sakka, E., Maconick, L. C., Doubal, F., Sudlow, C. & Wardlaw, J., 3 Nov 2016, In : Brain and Behavior.

    Research output: Contribution to journalArticle

  237. Cerebral small vessel disease burden is increased in systemic lupus erythematosus

    Wiseman, S., Bastin, M., Jardine, C., Barclay, G., Hamilton, I., Sandeman, E., Hunt, D., Amft, N., Thomson, S., Belch, J., Ralston, S. H. & Wardlaw, J., Nov 2016, In : Stroke.

    Research output: Contribution to journalArticle

  238. Automatic Generation of Synthetic Retinal Fundus Images: Vascular Network

    Menti, E., Bonaldi, L., Ballerini, L., Ruggeri, A. & Trucco, E., 21 Oct 2016, Simulation and Synthesis in Medical Imaging. Tsaftaris, S. (ed.). Springer, p. 167-186 (LNCS; no. 9968).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  239. Endovascular therapy for acute ischaemic stroke: the Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) randomised, controlled trial

    Muir, K. W., Ford, G. A., Messow, C-M., Ford, I., Murray, A., Clifton, A., Brown, M. M., Madigan, J., Lenthall, R., Robertson, F., Dixit, A., Cloud, G. C., Wardlaw, J., Freeman, J., White, P. & PISTE Investigators, 18 Oct 2016, In : Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journalArticle

  240. Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex

    Guadalupe, T., Mathias, S. R., vanErp, T. G. M., Whelan, C. D., Zwiers, M. P., Abe, Y., Abramovic, L., Agartz, I., Andreassen, O. A., Arias-Vásquez, A., Aribisala, B. S., Armstrong, N. J., Arolt, V., Artiges, E., Ayesa-Arriola, R., Baboyan, V. G., Banaschewski, T., Barker, G., Bastin, M. E., Baune, B. T. & 141 others, Blangero, J., Bokde, A. L. W., Boedhoe, P. S. W., Bose, A., Brem, S., Brodaty, H., Bromberg, U., Brooks, S., Büchel, C., Buitelaar, J., Calhoun, V. D., Cannon, D. M., Cattrell, A., Cheng, Y., Conrod, P. J., Conzelmann, A., Corvin, A., Crespo-Facorro, B., Crivello, F., Dannlowski, U., de Zubicaray, G. I., de Zwarte, S. M. C., Deary, I. J., Desrivières, S., Doan, N. T., Donohoe, G., Dørum, E. S., Ehrlich, S., Espeseth, T., Fernández, G., Flor, H., Fouche, J-P., Frouin, V., Fukunaga, M., Gallinat, J., Garavan, H., Gill, M., Suarez, A. G., Gowland, P., Grabe, H. J., Grotegerd, D., Gruber, O., Hagenaars, S., Hashimoto, R., Hauser, T. U., Heinz, A., Hibar, D. P., Hoekstra, P. J., Hoogman, M., Howells, F. M., Hu, H., Hulshoff Pol, H. E., Huyser, C., Ittermann, B., Jahanshad, N., Jönsson, E. G., Jurk, S., Kahn, R. S., Kelly, S., Kraemer, B., Kugel, H., Kwon, J. S., Lemaitre, H., Lesch, K-P., Lochner, C., Luciano, M., Marquand, A. F., Martin, N. G., Martínez-Zalacaín, I., Martinot, J-L., Mataix-Cols, D., Mather, K., McDonald, C., McMahon, K. L., Medland, S. E., Menchón, J. M., Morris, D. W., Mothersill, O., Maniega, S. M., Mwangi, B., Nakamae, T., Nakao, T., Narayanaswaamy, J. C., Nees, F., Nordvik, J. E., Onnink, A. M. H., Opel, N., Ophoff, R., Paillère Martinot, M-L., Papadopoulos Orfanos, D., Pauli, P., Paus, T., Poustka, L., Reddy, J. Y., Renteria, M. E., Roiz-Santiáñez, R., Roos, A., Royle, N. A., Sachdev, P., Sánchez-Juan, P., Schmaal, L., Schumann, G., Shumskaya, E., Smolka, M. N., Soares, J. C., Soriano-Mas, C., Stein, D. J., Strike, L. T., Toro, R., Turner, J. A., Tzourio-Mazoyer, N., Uhlmann, A., Hernández, M. V., van den Heuvel, O. A., van der Meer, D., van Haren, N. E. M., Veltman, D. J., Venkatasubramanian, G., Vetter, N. C., Vuletic, D., Walitza, S., Walter, H., Walton, E., Wang, Z., Wardlaw, J., Wen, W., Westlye, L. T., Whelan, R., Wittfeld, K., Wolfers, T., Wright, M. J., Xu, J., Xu, X., Yun, J-Y., Zhao, J., Franke, B., Thompson, P. M., Glahn, D. C., Mazoyer, B., Fisher, S. E. & Francks, C., 13 Oct 2016, In : Brain imaging and behavior.

    Research output: Contribution to journalArticle

  241. Cognitive reserve moderates long-term cognitive and functional outcome in cerebral small vessel disease

    Jokinen, H., Melkas, S., Madureira, S., Verdelho, A., Ferro, J. M., Fazekas, F., Schmidt, R., Scheltens, P., Barkhof, F., Wardlaw, J., Inzitari, D., Pantoni, L. & Erkinjuntti, T., 7 Oct 2016, In : Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journalArticle

  242. Novel genetic loci underlying human intracranial volume identified through genome-wide association

    Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van der Grond, J., Van der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C-Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., de Zubicaray, G. I., Delanty, N., Depondt, C., DeStefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B-C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J-J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jr, C. R. J., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Jr, W. T. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J-L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van der Brug, M., Van der Lugt, A., Van der Wee, N. J. A., Van Duijn, C. M., Van Haren, N. E. M., Van T Ent, D., Van Tol, M-J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., DeCarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., 3 Oct 2016, In : Nature Neuroscience.

    Research output: Contribution to journalArticle

  243. Associations between education and brain structure at age 73 years, adjusted for age 11 IQ

    Cox, S., Dickie, D. A., Ritchie, S. J., Karama, S., Pattie, A., Royle, N., Corley, J., Aribisala, B., Valdes Hernandez, M. C., Muñoz Maniega, S., Starr, J., Bastin, M., Evans, A. C., Wardlaw, J. & Deary, I., Oct 2016, In : Neurology. 87, 17, p. 1820-1826 7 p.

    Research output: Contribution to journalArticle

  244. Update on cerebral small vessel disease – a dynamic, whole-brain disease

    Shi, Y. & Wardlaw, J., 30 Sep 2016, In : Stroke and Vascular Neurology.

    Research output: Contribution to journalArticle

  245. Pseudo-Healthy Image Synthesis for White Matter Lesion Segmentation

    Bowles, C., Qin, C., Ledig, C., Moreno, R. G., Gunn, R., Hammers, A., Sakka, E., Dickie, D. A., Valdes Hernandez, M., Royle, N., Wardlaw, J., Rhodius-Meester, H., Tijms, B., Lemstra, A., van der Flier, W., Barkhof, F., Scheltens, P. & Rueckert, D., 23 Sep 2016, Simulation and Synthesis in Medical Imaging. SpringerLink, Vol. 9968. p. 87-96 (Lecture Notes in Computer Science).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  246. Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology

    Wardlaw, J. & Horsburgh, K., 22 Sep 2016, In : Clinical science.

    Research output: Contribution to journalEditorial

  247. Early life characteristics and late life burden of cerebral small vessel disease in the Lothian Birth Cohort 1936

    Field, T. S., Doubal, F., Johnson, W., Backhouse, E., McHutchison, C., Cox, S., Corley, J., Pattie, A., Gow, A., Shenkin, S., Cvoro, V., Morris, Z., Staals, J., Bastin, M., Deary, I. & Wardlaw, J., 19 Sep 2016, In : Aging. 8, 9, p. 2039-2061

    Research output: Contribution to journalArticle

  248. Multicenter Evaluation of Geometric Accuracy of MRI Protocols Used in Experimental Stroke

    Milidonis, X., Lennen, R. J., Jansen, M., Mueller, S., Boehm-Sturm, P., Holmes, W. M., Sena, E., MacLeod, M. & Marshall, I., 7 Sep 2016, In : PLoS ONE.

    Research output: Contribution to journalArticle

  249. Enlarged perivascular spaces and cognitive impairment after stroke and transient ischemic attack

    Arba, F., Quinn, T. J., Hankey, G. J., Lees, K. R., Wardlaw, J., Ali, M. & Inzitari, D., 19 Aug 2016, In : International Journal of Stroke.

    Research output: Contribution to journalArticle

  250. Effects of alteplase for acute stroke on the distribution of functional outcomes: a pooled analysis of nine trials

    Lees, K. R., Emberson, J., Blackwell, L., Bluhmki, E., Davis, S., Donnan, G. A., Grotta, J. C., Kaste, M., von Kummer, R., Lansberg, M. G., Lindley, R., Lyden, P., Murray, G., Sandercock, P., Toni, D., Toyoda, K., Wardlaw, J., Whiteley, W., Baigent, C., Hacke, W. & 1 others, Howard, G., 9 Aug 2016, In : Stroke.

    Research output: Contribution to journalArticle

  251. Cerebral blood flow in small vessel disease: a systematic review and meta-analysis

    Shi, Y., Thrippleton, M., Makin, S., Marshall, I., Geerlings, M. I., de Craen, A. J. M., Van Buchem, M. A. & Wardlaw, J., 5 Aug 2016, In : Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalArticle

  252. Application of the ordered logit model to optimising Frangi filter parameters for segmentation of perivascular spaces

    Ballerini, L., Lovreglio, R., Valdes Hernandez, M., Gonzalez-Castro, V., Muñoz Maniega, S., Pellegrini, E., Bastin, M., Deary, I. & Wardlaw, J., 25 Jul 2016, In : Procedia Computer Science. p. 61-67

    Research output: Contribution to journalArticle

  253. Automatic Generation of Synthetic Retinal Fundus Images: Vascular Network

    Bonaldi, L., Menti, E., Ballerini, L., Ruggeri, A. & Trucco, E., 25 Jul 2016, In : Procedia Computer Science. p. 54-60

    Research output: Contribution to journalArticle

  254. Texture-based classification for the automatic rating of the perivascular spaces in brain MRI

    Gonzalez-Castro, V., Valdes Hernandez, M., Armitage, P. & Wardlaw, J., 25 Jul 2016, In : Procedia Computer Science. 90, p. 9-14

    Research output: Contribution to journalArticle

  255. Effects of alteplase on survival after ischaemic stroke (IST-3): 3 year follow-up of a randomised, controlled, open-label trial

    Berge, E., Cohen, G., Roaldsen, M. B., Lundstrom, E., Isaksson, E., Rudberg, A-S., Slot, K. B., Forbes, J., Smith, J. W. S., Drever, J., Wardlaw, J., Lindley, R. I., Sandercock, P. & Whiteley, W., 19 Jul 2016, In : Lancet Neurology.

    Research output: Contribution to journalArticle

  256. Automatic rating of perivascular spaces in brain MRI using bag of visual words

    Gonzalez-Castro, V., Valdes Hernandez, M., Armitage, P. & Wardlaw, J., 1 Jul 2016, Image Analysis and Recognition. SpringerLink, Vol. 9730. (Lecture Notes in Computer Science).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  257. Do white matter hyperintensities mediate the association between brain iron deposition and cognitive abilities in older people?

    Valdes Hernandez, M., Allerhand, M., Glatz, A., Clayson, L., Munoz-Maniega, S., Gow, A., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Jul 2016, In : European Journal of Neurology. 23, p. 1202-1209

    Research output: Contribution to journalArticle

  258. Leveraging Multiscale Hessian-based Enhancement with a Novel Exudate Inpainting Technique for Retinal Vessel Segmentation

    Annunziata, R., Garzelli, A., Ballerini, L., Mecocci, A. & Trucco, E., Jul 2016, In : IEEE Journal of Biomedical and Health Informatics. 20, 4, p. 1129-1138

    Research output: Contribution to journalArticle

  259. Automatic Generation of Synthetic Retinal Fundus Images: Vascular Network

    Bonaldi, L., Menti, E., Ballerini, L., Ruggeri, A. & Trucco, E., 17 Jun 2016.

    Research output: Contribution to conferencePoster

  260. Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis

    Whiteley, W. N., Emberson, J., Lees, K. R., Blackwell, L., Albers, G., Bluhmki, E., Brott, T., Cohen, G., Davis, S., Donnan, G., Grotta, J., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Lyden, P., Olivot, J. M., Parsons, M. & 8 others, Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., del Zoppo, G. J., Sandercock, P., Hacke, W. & Baigent, C., 8 Jun 2016, In : Lancet Neurology.

    Research output: Contribution to journalArticle

  261. 3D shape analysis of the brain's third ventricle using a midplane encoded symmetric template model

    Kim, J., Valdes Hernandez, M., Royle, N., Muñoz Maniega, S., Aribisala, B., Gow, A., Bastin, M., Deary, I., Wardlaw, J. & Park, J., Jun 2016, In : Computer methods and programs in biomedicine. 129, p. 51-62

    Research output: Contribution to journalArticle

  262. Reproducibility and variability of quantitative MRI markers in cerebral small vessel disease

    De Guio, F., Jouvent, E., Biessels, G. J., Black, SE., Brayne, C., Chen, C., Cordonnier, C., de Leeuw, F-E., Dichgans, M., Doubal, F., Duering, M., Dufouil, C., Duzel, E., Fazekas, F., Hachinski, V., Ikram, M. A., Linn, J., Matthews, P. M., Mazoyer, B., Mok, V. & 21 others, Norrving, B., O'Brien, J. T., Pantoni, L., Ropele, S., Sachdev, P. S., Schmidt, R., Seshadri, S., Smith, E. E., Sposato, LA., Stephan, B., Swartz, R., Tzourio, C., van Buchem, M., van der Lugt, A., van Oostenbrugge, R., Vernooij, M. W., Viswanathan, A., Werring, D., Wollenweber, F., Wardlaw, J. & Chabriat, H., 11 May 2016, In : Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalArticle

  263. IST-3 stroke trial data available

    Sandercock, P., Wardlaw, J., Lindley, R., Whiteley, W. & Cohen, G., 7 May 2016, In : The Lancet. 387, 10031

    Research output: Contribution to journalLetter

  264. Modulation of retinal image vasculature analysis to extend utility and provide secondary value from optical coherence tomography imaging

    Cameron, J., Ballerini, L., Langan, C., Warren, C., Denholm, N., Smart, K. & MacGillivray, T., 2 May 2016, In : Journal of Medical Imaging. 3, 2

    Research output: Contribution to journalLetter

  265. Continuing versus Stopping Prestroke Antihypertensive Therapy in Acute Intracerebral Hemorrhage: A Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke Trial

    Krishnan, K., Scutt, P., Woodhouse, L., Adami, A., Becker, J. L., Cala, L. A., Casado, A. M., Chen, C., Dineen, R. A., Gommans, J., Koumellis, P., Christensen, H., Collins, R., Czlonkowska, A., Lees, K. R., Ntaios, G., Ozturk, S., Phillips, S. J., Sprigg, N., Szatmari, S. & 2 others, Wardlaw, J. M. & Bath, P. M., 1 May 2016, In : Journal of Stroke and Cerebrovascular Diseases. 25, 5, p. 1017-1026 10 p.

    Research output: Contribution to journalArticle

  266. Imaging signatures of meningioma and low-grade glioma: a diffusion tensor, magnetization transfer and quantitative longitudinal relaxation time MRI study

    Piper, R. J., Mikhael, S., Wardlaw, J., Laidlaw, D. H., Whittle, I. & Bastin, M., May 2016, In : Magnetic Resonance Imaging. 34, p. 596-602

    Research output: Contribution to journalArticle

  267. Magnetic Resonance Imaging for Assessment of Cerebrovascular Reactivity in Cerebral Small Vessel Disease. A Systematic Review.

    Blair, G., Doubal, F., Thrippleton, M., Marshall, I. & Wardlaw, J., May 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, p. 833-41

    Research output: Contribution to journalArticle

  268. Observer reliability of CT Perfusion scans

    El Tawil, S., Mair, G., Huang, X., Sakka, E., Palmer, J., Ford, I., Kalra, L., Muir, K. & Wardlaw, J., May 2016, p. 447-448. 2 p.

    Research output: Contribution to conferencePoster

  269. Visual Scoring Versus Computational Volume Measures of Perfusion Defects In Acute Ischaemic Stroke

    Mair, G., Carpenter, T., Cohen, G., Lindley, R., Sandercock, P. & Wardlaw, J., May 2016, p. 458. 1 p.

    Research output: Contribution to conferencePoster

  270. Cytomegalovirus infection is associated with an increase in systolic blood pressure in older individuals

    Firth, C., Wardlaw, J., Ritchie, S. J., Ferro, C. J., Deary, I., Starr, J. & Moss, P., 12 Apr 2016, In : QJM: An International Journal of Medicine. 109, 9, p. 595-600 hcw026.

    Research output: Contribution to journalArticle

  271. Cerebrovascular disease in rheumatic diseases. A systematic review and meta-analysis

    Wiseman, S., Ralston, S. & Wardlaw, J., Apr 2016, In : Stroke. 47, p. 943-950

    Research output: Contribution to journalArticle

  272. Trait Conscientiousness and the Personality Meta-Trait Stability are Associated with Regional White Matter Microstructure

    Lewis, G. J., Cox, S., Booth, T., Muñoz Maniega, S., Royle, N., Valdes Hernandez, M., Wardlaw, J., Bastin, M. & Deary, I., 24 Mar 2016, In : Social Cognitive and Affective Neuroscience.

    Research output: Contribution to journalArticle

  273. Polygenic risk of ischemic stroke is associated with cognitive ability

    Harris, S. E., Malik, R., Marioni, R., Campbell, A., Seshadri, S., Worrall, B. B., Sudlow, C. L. M., Hayward, C., Bastin, M. E., Starr, J. M., Porteous, D. J., Wardlaw, J. M., Deary, I. J. & METASTROKE Consortium, 16 Feb 2016, In : Neurology. 86, 7, p. 611-618

    Research output: Contribution to journalArticle

  274. A structural and functional magnetic resonance imaging dataset of brain tumour patients.

    Pernet, C., Krzysztof, G., Job, D., Rodriguez Gonzalez, D., Whittle, I. & Wardlaw, J., 2 Feb 2016, In : Scientific Data. 6 p., 160003.

    Research output: Contribution to journalArticle

  275. Cerebral small vessel disease: capillary pathways to stroke and cognitive decline

    Ostergaard, L., Sondergaard, T., Moreton, F., Hansen, MB., Wardlaw, J., Dalkara, T., Markus, H. S. & Muir, K., Feb 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 302-325

    Research output: Contribution to journalArticle

  276. Evaluation of a pre-surgical functional MRI workflow: From data acquisition to reporting

    Pernet, C., Krzysztof, G., Job, D., Rodriguez Gonzalez, D., Storkey, A., Whittle, I. & Wardlaw, J., Feb 2016, In : International journal of medical informatics. 86, p. 37-42 6 p.

    Research output: Contribution to journalArticle

  277. Identification of imaging selection patterns in acute ischemic stroke patients and the influence on treatment and clinical trial enrolment decision making

    Luby, M., Warach, S. J., Albers, G. W., Baron, JC., Cognard, C., Dávalos, A., Donnan, G. A., Fiebach, JB., Fiehler, J., Hacke, W., Lansberg, M. G., Liebeskind, DS., Mattle, H. P., Oppenheim, C., Schellinger, P. D., Wardlaw, J. & Wintermark, M., Feb 2016, In : International Journal of Stroke. 11, p. 180-190

    Research output: Contribution to journalArticle

  278. Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

    Hagenaars, S. P., Harris, S. E., Davies, G., Hill, W. D., Liewald, D. C. M., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Cullen, B., Malik, R., Worrall, B. B., Sudlow, C. L. M., Wardlaw, J. M., Gallacher, J., Pell, J., McIntosh, A. M., Smith, D. J., Gale, C. R., Deary, I. J. & METASTROKE Consortium, International Consortium for Blood Pressure GWAS, 26 Jan 2016, In : Molecular Psychiatry. 21, 11, p. 1624-1632

    Research output: Contribution to journalArticle

  279. A brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS)

    Job, D., Dickie, D. A., Rodriguez Gonzalez, D., Robson, A., Danso, S., Pernet, C., Bastin, M., Boardman, J. P., Murray, A. D., Ahearn, T. S., Waiter, G. D., Staff, R. T., Deary, I., Shenkin, S. D. & Wardlaw, J., 18 Jan 2016, In : NeuroImage.

    Research output: Contribution to journalArticle

  280. Development and initial evaluation of a semi-automatic approach to assess perivascular spaces on conventional magnetic resonance images

    Wang, X., Valdes Hernandez, M., Doubal, F., Chappell, F., Piper, R. J., Deary, I. & Wardlaw, J., 15 Jan 2016, In : Journal of Neuroscience Methods. 257, p. 34-44

    Research output: Contribution to journalArticle

  281. Effect of alteplase on the CT hyperdense artery sign and functional outcome after ischemic stroke

    Mair, G., von Kummer, R., Morris, Z., von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A., Adami, A., Potter, G., Cohen, G., Sandercock, P., Lindley, R., Wardlaw, J. & IST-3 Collaborative Group, 12 Jan 2016, In : Neurology. 86, p. 1-8

    Research output: Contribution to journalArticle

  282. Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

    Traylor, M., Zhang, CR., Adib-samii, P., Devan, WJ., Parsons, OE., Lanfranconi, S., Gregory, S., Cloonan, L., Falcone, GJ., Radmanesh, F., Fitzpatrick, K., Kanakis, A., Barrick, T. R., Moynihan, B., Lewis, CM., Boncoraglio, G., Lemmens, R., Thijs, V., Sudlow, C., Wardlaw, J. & 11 others, Rothwell, P. M., Meschia, J. F., Worrall, B. B., Levi, C., Bevan, S., Furie, K. L., Dichgans, M., Rosand, J., Markus, H. S., Rost, NS. & the International Stroke Genetics Consortium, 12 Jan 2016, In : Neurology. 86, p. 146-153

    Research output: Contribution to journalArticle

  283. Blood pressure and sodium: association with MRI markers in cerebral small vessel disease

    Heye, A. K., Thrippleton, M., Chappell, F., Valdes Hernandez, M., Armitage, P., Makin, S., Munoz-Maniega, S., Sakka, E., Flatman, P., Dennis, M. & Wardlaw, J., Jan 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, p. 264-274

    Research output: Contribution to journalArticle

  284. Consensus statement for diagnosis of subcortical small vessel disease

    Rosenberg, GA., Wallin, A., Wardlaw, J., Markus, H. S., Montaner, J., Wolfson, L., Iadecola, C., Zlokovic, BV., Joutel, A., Dichgans, M., Duering, M., Schmidt, R., Koczyn, A., Grinberg, LT., Chui, HC. & Hachinski, V., Jan 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, p. 6-25

    Research output: Contribution to journalArticle

  285. Retinal Vessel Classification Based on Maximization of Squared-Loss Mutual Information

    Relan, D., Ballerini, L., Trucco, E. & MacGillivray, T., Jan 2016, Machine Intelligence and Signal Processing. Singh, R. (ed.). Springer, p. 77 84 p. (Advances in Intelligent Systems and Computing ; vol. 390).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  286. Tracer kinetic modelling for DCE-MRI quantification of subtle blood-brain barrier permeability

    Heye, A. K., Thrippleton, M., Armitage, P., Thrippleton, M., Valdes Hernandez, M., Makin, S., Glatz, A., Sakka, E. & Wardlaw, J., Jan 2016, In : NeuroImage. 125, p. 446–455

    Research output: Contribution to journalArticle

  287. A Tool For Gyral Ground Truth Measurements

    Mikhael, S., Gray, C., MacGillivray, T., Murray, A., Hoogendoorn, C., Valdes Hernandez, M., Wardlaw, J. & Pernet, C., 2016.

    Research output: Contribution to conferencePaper

  288. Effect of treatment delay, stroke type, and thrombolysis on the effect of glyceryl trinitrate, a nitric oxide donor, on outcome after acute stroke: a systematic review and meta-analysis of individual patient from randomised trials

    Bath, P. M. W., Woodhouse, L., Krishnan, K., Anderson, C., Berge, E., Ford, G., Robinson, T., Saver, JL., Sprigg, N. & Wardlaw, J., 2016, In : Stroke research and treatment. 2016

    Research output: Contribution to journalArticle

  289. 2015
  290. Effect of X-Ray Attenuation of Arterial Obstructions on Intravenous Thrombolysis and Outcome after Ischemic Stroke

    Mair, G., von Kummer, R., Lindley, R., Sandercock, P., Wardlaw, J. & IST-3 Collaborative Group, 23 Dec 2015, In : PLoS ONE. 10, e0145683.

    Research output: Contribution to journalArticle

  291. Progression of white matter disease and cortical thinning are not related in older community-dwelling subjects

    Dickie, D. A., Karama, S., Ritchie, S. J., Cox, S. R., Sakka, E., Royle, N. A., Aribisala, B. S., Hernández, M. V., Maniega, S. M., Pattie, A., Corley, J., Starr, J. M., Bastin, M. E., Evans, A. C., Deary, I. J. & Wardlaw, J. M., 22 Dec 2015, In : Stroke. 47, 2, p. 410-6 7 p.

    Research output: Contribution to journalArticle

  292. Glyceryl Trinitrate for Acute Intracerebral Hemorrhage. Results From the Efficacy of Nitric Oxide in Stroke (ENOS) Trial, a Subgroup Analysis

    Krishnan, K., Scutt, P., Woodhouse, L., Adami, A., Becker, JL., Berge, E., Cala, L., Casado, A., Caso, V., Chen, C., Christensen, H., Collins, R., Czlonkowska, A., Lees, K. R., Ntaios, G., Ozturk, S., Phillips, S. J., Pocock, S. J., de Silva, A., Sprigg, N. & 3 others, Szatmari, S., Wardlaw, J. & Bath, P. M. W., 8 Dec 2015, In : Stroke.

    Research output: Contribution to journalArticle

  293. ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide

    Thompson, P. M., Andreassen, O. A., Arias-Vasquez, A., Bearden, C. E., Boedhoe, P. S., Brouwer, R. M., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cannon, D. M., Cohen, R. A., Conrod, P. J., Dale, A. M., Deary, I. J., Dennis, E. L., de Reus, M. A., Desrivieres, S., Dima, D., Donohoe, G., Fisher, S. E. & 31 others, Fouche, J-P., Francks, C., Frangou, S., Franke, B., Ganjgahi, H., Garavan, H., Glahn, D. C., Grabe, H. J., Guadalupe, T., Gutman, B. A., Hashimoto, R., Hibar, D. P., Holland, D., Hoogman, M., Pol, H. E. H., Hosten, N., Jahanshad, N., Kelly, S., Kochunov, P., Kremen, W. S., Lee, P. H., Mackey, S., Martin, N. G., Mazoyer, B., McDonald, C., Medland, S. E., Morey, R. A., Nichols, T. E., Paus, T., Wardlaw, J. M. & ENIGMA Consortium, 4 Dec 2015, In : NeuroImage.

    Research output: Contribution to journalArticle

  294. APOE/TOMM40 genetic loci, white matter hyperintensities and cerebral microbleeds

    Lyall, D. M., Munoz-Maniega, S., Harris, S., Bastin, M., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Valdes Hernandez, M., Royle, N., Starr, J., Porteous, D., Deary, I. & Wardlaw, J., Dec 2015, In : International Journal of Stroke. 10, 8, p. 1297-1300

    Research output: Contribution to journalArticle

  295. Brain volumetric changes and cognitive ageing during the eighth decade of life

    Ritchie, S. J., Dickie, D., Cox, S., Valdes Hernandez, M., Corley, J., Royle, N., Pattie, A., Aribisala, B., Redmond, P., Munoz-Maniega, S., Taylor, A., Sibbett, R., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Dec 2015, In : Human Brain Mapping. 36, p. 4910–4925

    Research output: Contribution to journalArticle

  296. Permutation and parametric tests for effect sizes in voxel-based morphometry of grey matter volume in brain structural MRI

    Dickie, D. A., Mikhael, S., Job, D. E., Wardlaw, J. M., Laidlaw, D. H. & Bastin, M. E., Dec 2015, In : Magnetic Resonance Imaging. 33, p. 1299-1305

    Research output: Contribution to journalArticle

  297. Acting on incidental findings in research imaging

    Wardlaw, J. M., Davies, H., Booth, T. C., Laurie, G., Compston, A., Freeman, C., Leach, M. O., Waldman, A., Lomas, D. J., Kessler, K., Crabbe, F. & Jackson, A., 10 Nov 2015, In : British Medical Journal (BMJ). 351, p. h5190

    Research output: Contribution to journalArticle

  298. Baseline characteristics, analysis plan and report on feasibility for the Prevention Of Decline in Cognition After Stroke Trial (PODCAST)

    Scutt, P., Daniel, B., Krishnan, K., Ballard, C., Burns, A., Ford, G. A., Mant, J., Passmore, P. A., Pocock, S. J., Reckless, J., Sprigg, N., Stewart, R., Wardlaw, J. & Bath, P. M. W., 7 Nov 2015, In : Trials. 16, p. 509

    Research output: Contribution to journalArticle

  299. Thrombectomy for Acute Ischemic Stroke

    Wardlaw, J. M. & Dennis, M. S., 3 Nov 2015, In : Journal of the American Medical Association (JAMA). 314, 17, p. 1803-1805 3 p.

    Research output: Contribution to journalEditorial

  300. Association between retinal vasculature and muscle mass in older people

    Sumukadas, D., McMurdo, M., Pieretti, I., Ballerini, L., Price, R., Wilson, P., Doney, A., Leese, G. & Trucco, E., Nov 2015, In : Archives of Gerontology and Geriatrics. 61, 3, p. 425-428 4 p.

    Research output: Contribution to journalArticle

  301. Effect of Hyperacute Administration (Within 6 Hours) of Transdermal Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome After Stroke: Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial

    Woodhouse, L., Scutt, P., Krishnan, K., Berge, E., Gommans, J., Ntaios, G., Wardlaw, J., Sprigg, N., Bath, P. M. & ENOS Investigators, Nov 2015, In : Stroke; a journal of cerebral circulation. 46, 11, p. 3194-201 8 p.

    Research output: Contribution to journalArticle

  302. Brain iron deposits and lifespan cognitive ability

    Valdes Hernandez, M., Ritchie, S. J., Glatz, A., Allerhand, M., Munoz-Maniega, S., Gow, A., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Oct 2015, In : AGE. 37, p. 100

    Research output: Contribution to journalArticle

  303. Morphological MRI characteristics of recent small subcortical infarcts

    Gattringer, T., Eppinger, S., Pinter, D., Pirpamer, L., Berghold, A., Wuensch, G., Ropele, S., Wardlaw, J., Enzinger, C. & Fazekas, F., Oct 2015, In : International Journal of Stroke. 10, p. 1037-1043

    Research output: Contribution to journalArticle

  304. Accuracy of Patient Self-Report of Stroke: A Systematic Review from the UK Biobank Stroke Outcomes Group

    UK Biobank Stroke Outcomes Group, UK Biobank Follow-up and Outcomes Working Group & Wardlaw, J., 10 Sep 2015, In : PLoS ONE. 10, 9, p. e0137538

    Research output: Contribution to journalArticle

  305. Post-mortem brain analyses of the Lothian Birth Cohort 1936: Extending lifetime cognitive and brain phenotyping to the level of the synapse

    Henstridge, C., JAckson, R., Kim, J., Herrmann, A., Wright, A. K., Harris, S., Bastin, M., Starr, J., Wardlaw, J., Gillingwater, T., Smith, C., McKenzie, C-A., Cox, S., Deary, I. & Spires-Jones, T., 4 Sep 2015, In : Acta neuropathologica communications. 3, 53

    Research output: Contribution to journalArticle

  306. Early life risk factors for stroke and cognitive impairment

    Backhouse, EV., McHutchison, C., Cvoro, V., Shenkin, S. & Wardlaw, J., Sep 2015, In : Current Epidemiology Reports. 2, 3, p. 172-179

    Research output: Contribution to journalArticle

  307. Phase-based Metamorphosis of Diffusion Lesion in Relation to Perfusion Values in Acute Ischemic Stroke

    Rekik, I., Allassonnière, S., Luby, M., Carpenter, T. & Wardlaw, J., Sep 2015, In : NeuroImage: Clinical. 9, p. 44-49

    Research output: Contribution to journalArticle

  308. Plasma biomarkers of inflammation, endothelial function and haemostasis in cerebral small vessel disease

    Wiseman, S., Doubal, F., Chappell, F., Valdes Hernandez, M., Wang, X., Rumley, A., Lowe, G. D. O., Dennis, M. & Wardlaw, J., Sep 2015, In : Cerebrovascular diseases. 40, 3-4, p. 157-164

    Research output: Contribution to journalArticle

  309. Consent for brain tissue donation after intracerebral haemorrhage: a community-based study

    Samarasekera, N., Lerpiniere, C., Fonville, A., Farrall, A., Wardlaw, J., White, P., Torgersen, A., Ironside, J., Smith, C., Salman, R., Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators & Reed, M. J., 24 Aug 2015, In : PLoS ONE. 10, 8, e0135043.

    Research output: Contribution to journalArticle

  310. Protocol for the perfusion and angiography imaging sub-study of the Third International Stroke Trial (IST-3) of alteplase treatment within six-hours of acute ischemic stroke

    Wardlaw, J. M., von Kummer, R., Carpenter, T., Parsons, M., Lindley, R. I., Cohen, G., Murray, V., Kobayashi, A., Peeters, A., Chappell, F. & Sandercock, P. A. G., Aug 2015, In : International Journal of Stroke. 10, 6, p. 956-968

    Research output: Contribution to journalArticle

  311. ABCD2 score and secondary stroke prevention. Meta-analysis and effect per 1000 patients triaged

    Wardlaw, J., Brazzelli, M., Chappell, F., Miranda, H., Shuler, K., Sandercock, P. & Dennis, M., 28 Jul 2015, In : Neurology. 85, p. 1-8

    Research output: Contribution to journalLiterature review

  312. Beyond a bigger brain: Multivariable structural brain imaging and intelligence

    Ritchie, S., Booth, T., Valdes Hernandez, M., Corley, J., Munoz-Maniega, S., Gow, A., Royle, N., Pattie, A., Karama, S., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Jul 2015, In : Intelligence. 51, p. 47–56 10 p.

    Research output: Contribution to journalArticle

  313. International survey of acute stroke imaging used to make revascularization treatment decisions

    Wintermark, M., Luby, M., Bornstein, N. M., Demchuk, A., Fiehler, J., Kudo, K., Lees, K. R., Liebeskind, D. S., Michel, P., Nogueira, R. G., Parsons, M. W., Sasaki, M., Wardlaw, J. M., Wu, O., Zhang, W., Zhu, G. & Warach, S. J., Jul 2015, In : International Journal of Stroke. 10, 5, p. 759-62 4 p.

    Research output: Contribution to journalArticle

  314. Effect of intravenous recombinant tissue-type plasminogen activator in patients with mild stroke in the Third International Stroke Trial-3: post hoc analysis

    Khatri, P., Tayama, D., Cohen, G., Lindley, R., Wardlaw, J., Yeatts, SD., Broderick, JP. & Sandercock, P., 23 Jun 2015, In : Stroke.

    Research output: Contribution to journalArticle

  315. What are white matter hyperintensities made of? Relevance to vascular cognitive impairment

    Wardlaw, J., Valdes Hernandez, M. & Munoz-Maniega, S., 23 Jun 2015, In : Journal of the American Heart Association. 4, p. 001140

    Research output: Contribution to journalArticle

  316. Coupled changes in brain white matter microstructure and fluid intelligence in later life

    Ritchie, S., Bastin, M., Tucker-Drob, E. M., Munoz-Maniega, S., Engelhardt, L., Cox, S. R., Royle, N., Gow, A., Corley, J., Pattie, A., Taylor, A., Valdes Hernandez, M., Starr, J., Wardlaw, J. & Deary, I., 3 Jun 2015, In : The Journal of Neuroscience. 35, 22, p. 8672-8682 11 p.

    Research output: Contribution to journalArticle

  317. Hippocampal shape modeling based on a progressive template surface deformation and its verification

    Kim, J., Valdes Hernandez, M., Royle, N., Park, J., The Lothian Birth Cohort 1936 Collaborative Group & The Alzheimer’s Disease Neuroimaging Initiative, Jun 2015, In : IEEE Transactions on Medical Imaging. 99

    Research output: Contribution to journalArticle

  318. HydroCoils Reduce Recurrence Rates in Recently Ruptured Medium-Sized Intracranial Aneurysms: A Subgroup Analysis of the HELPS Trial

    Brinjikji, W., White, P. M., Nahser, H., Wardlaw, J., Sellar, R., Cloft, H. J., Kallmes, D. F. & Sellar, R., Jun 2015, In : American Journal of Neuroradiology. 36, 6

    Research output: Contribution to journalArticle

  319. Pharmacological treatment and prevention of cerebral small vessel disease: a review of potential interventions

    Bath, P. M. W. & Wardlaw, J., Jun 2015, In : International Journal of Stroke. 10, 4, p. 469–478

    Research output: Contribution to journalLiterature review

  320. Proton spectroscopic imaging of brain metabolites in basal ganglia of healthy older adults

    Parikh, J., Thrippleton, M., Murray, C., Armitage, P., Harris, BA., Andrews, P., Wardlaw, J., Starr, J., Deary, I. & Marshall, I., Jun 2015, In : Magnetic Resonance Materials in Physics, Biology and Medicine. 28, 3, p. 251-257

    Research output: Contribution to journalArticle

  321. Use of brain MRI atlases to determine boundaries of age-related pathology: the importance of statistical method

    Dickie, D., Job, D., Rodriguez, D., Shenkin, S. & Wardlaw, J., 29 May 2015, In : PLoS ONE. 10, 5, e0127939.

    Research output: Contribution to journalArticle

  322. Suitability of UK Biobank Retinal Images for Automatic Analysis of Morphometric Properties of the Vasculature

    MacGillivray, T. J., Cameron, J. R., Zhang, Q., El-Medany, A., Mulholland, C., Sheng, Z., Dhillon, B., Doubal, F. N., Foster, P. J., Trucco, E., Sudlow, C. & UK Biobank Eye and Vision Consortium, 23 May 2015, In : PLoS ONE. 10, 5, p. e0127914

    Research output: Contribution to journalArticle

  323. Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial

    Wardlaw, J. M., Sandercock, P., Cohen, G., Farrall, A., Lindley, R. I., von Kummer, R., von Heijne, A., Bradey, N., Peeters, A., Cala, L., Adami, A., Morris, Z., Potter, G., Murray, G., Whiteley, W., Perry, D. & Sakka, E., May 2015, In : Lancet Neurology. 14, 5, p. 485-496 12 p.

    Research output: Contribution to journalArticle

  324. Intelligence in childhood and atherosclerosis of the carotid and peripheral arteries in later life: The Lothian Birth Cohort 1936

    Gale, C., Eadie, E., Thomas, A., Bastin, M., Starr, J., Wardlaw, J. & Deary, I., 27 Apr 2015, In : PLoS ONE. 10, 4, 7 p., e0125280.

    Research output: Contribution to journalArticle

  325. Common genetic variants influence human subcortical brain structures

    Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 31 others, Cuellar-Partida, G., den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., Macare, C., Liewald, D. C. M., Lopez, L. M., Royle, N. A., Bastin, M. E., Lawrie, S. M., Smith, C., Sussmann, J. E., Valdés Hernández, M. C., Deary, I. J., McIntosh, A. M., Wardlaw, J. M. & The Alzheimer’s Disease Neuroimaging Initiative, 9 Apr 2015, In : Nature. 520, 7546, p. 224-U216 21 p.

    Research output: Contribution to journalLetter

  326. Cochrane reviewers’ response to Alper and colleagues’ analysis of thrombolysis in acute ischaemic stroke

    Wardlaw, J. & Berge, E., 7 Apr 2015, In : British Medical Journal (BMJ). 350, p. h1790

    Research output: Contribution to journalLetter

  327. Cerebral lesions on 7 Tesla MRI in patients with sickle cell anemia

    van der Land, V., Zwaneburg, JJ., Fijnvandraat, K., Biemond, BJ., Hendrikse, J., Mutsaerts, HJ., Visser, F., Wardlaw, J., Nederveen, AJ., Majoie, CB. & Nederkoorn, P. J., Apr 2015, In : Cerebrovascular diseases. 39, p. 181-189

    Research output: Contribution to journalArticle

  328. Cerebral perivascular spaces visible on magnetic resonance imaging: Development of a qualitative rating scale and its observer reliability

    Potter, G., Chappell, F., Morris, Z. & Wardlaw, J., Apr 2015, In : Cerebrovascular diseases. 39, p. 224-231

    Research output: Contribution to journalArticle

  329. Enlarged perivascular spaces and cerebral small vessel disease

    Potter, G. M., Doubal, F. N., Jackson, C., Chappell, F. M., Sudlow, C., Dennis, M. S. & Wardlaw, J. M., Apr 2015, In : International Journal of Stroke. 10, 3, p. 376-381

    Research output: Contribution to journalArticle

  330. Multi-Ethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI

    Verhaaren, B. F. J., Debette, S., Bis, J. C., Smith, J. A., Ikram, M. K., Adams, H. H., Beecham, A. H., Rajan, K. B., Lopez, L. M., Barral, S., van Buchem, M. A., van der Grond, J., Smith, A. V., Hegenscheid, K., Aggarwal, N. T., de Andrade, M., Atkinson, E. J., Beekman, M., Beiser, A. S., Blanton, S. H. & 82 others, Boerwinkle, E., Brickman, A. M., Bryan, R. N., Chauhan, G., Chen, C. P. L. H., Chouraki, V., de Craen, A. J. M., Crivello, F., Deary, I. J., Deelen, J., De Jager, P. L., Dufouil, C., Elkind, M. S. V., Evans, D. A., Freudenberger, P., Gottesman, R. F., Guðnason, V., Habes, M., Heckbert, S. R., Heiss, G., Hilal, S., Hofer, E., Hofman, A., Ibrahim-Verbaas, C. A., Knopman, D. S., Lewis, C. E., Liao, J., Liewald, D. C. M., Luciano, M., van der Lugt, A., Martinez, O. O., Mayeux, R., Mazoyer, B., Nalls, M. A., Nauck, M., Niessen, W. J., Oostra, B. A., Psaty, B. M., Rice, K. M., Rotter, J. I., von Sarnowski, B., Schmidt, H., Schreiner, P. J., Schuur, M., Sidney, S. S., Sigurdsson, S., Slagboom, P. E., Stott, D. J. M., van Swieten, J. C., Teumer, A., Töglhofer, A. M., Traylor, M., Trompet, S., Turner, S. T., Tzourio, C., Uh, H-W., Uitterlinden, A. G., Vernooij, M. W., Wang, J. J., Wong, T. Y., Wardlaw, J. M., Windham, B. G., Wittfeld, K., Wolf, C., Wright, C. B., Yang, Q., Zhao, W., Zijdenbos, A., Jukema, J. W., Sacco, R. L., Kardia, S. L. R., Amouyel, P., Mosley, T. H., Longstreth, W. T., DeCarli, C. C., van Duijn, C. M., Schmidt, R., Launer, L. J., Grabe, H. J., Seshadri, S. S., Ikram, M. A. & Fornage, M., Apr 2015, In : Circulation. Cardiovascular genetics. 8, 2, p. 398-+ 54 p.

    Research output: Contribution to journalArticle

  331. Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data

    Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T. E., Wright, S. N., Hong, L. E., Patel, B., Behrens, T., Jbabdi, S., Andersson, J., Lenglet, C., Yacoub, E., Moeller, S., Auerbach, E., Ugurbil, K., Sotiropoulos, S. N., Brouwer, R. M., Landman, B. & 33 others, Lemaitre, H., den Braber, A., Zwiers, M. P., Ritchie, S., van Hulzen, K., Almasy, L., Curran, J., deZubicaray, G. I., Duggirala, R., Fox, P., Martin, N. G., McMahon, K. L., Mitchell, B., Olvera, R. L., Peterson, C., Starr, J., Sussmann, J., Wardlaw, J., Wright, M., Boomsma, D. I., Kahn, R., de Geus, E. J. C., Williamson, D. E., Hariri, A., van 't Ent, D., Bastin, M. E., McIntosh, A., Deary, I. J., Hulshoff Pol, H. E., Blangero, J., Thompson, P. M., Glahn, D. C. & Van Essen, D. C., 4 Mar 2015, In : NeuroImage. 111, p. 300-311 12 p.

    Research output: Contribution to journalArticle

  332. Alteplase for Acute Ischemic Stroke: Outcomes by Clinically Important Subgroups in the Third International Stroke Trial

    Lindley, R. I., Wardlaw, J. M., Whiteley, W. N., Cohen, G., Blackwell, L., Murray, G. D., Sandercock, P. A. G., on behalf of the IST-3 Collaborative Group, Sellar, R. & Farrall, A., Mar 2015, In : Stroke. 46, 3, p. 746-756 11 p.

    Research output: Contribution to journalArticle

  333. Association of allostatic load with brain structure and cognitive ability in later life

    Booth, T., Royle, N. A., Corley, J., Gow, A. J., Valdés Hernández, M. D. C., Munoz-Maniega, S., Ritchie, S. J., Bastin, M. E., Starr, J. M., Wardlaw, J. M. & Deary, I. J., Mar 2015, In : Neurobiology of Aging. 36, 3, p. 1390-1399 10 p.

    Research output: Contribution to journalArticle

  334. Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

    Holland, P., Searcy, L., Salvadores, N., Scullion, G., Chen, G., Lawson, G., Scott, F., Bastin, M., Ihara, M., Kalaria, R. N., Wood, E., Smith, C., Wardlaw, J. & Horsburgh, K., 21 Feb 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, 6, p. 1005-1014

    Research output: Contribution to journalArticle

  335. Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial

    Bath, P. M. W., Woodhouse, L., Scutt, P., Krishnan, K., Wardlaw, J. M., Bereczki, D., Sprigg, N., Berge, E., Beridze, M., Caso, V., Chen, C., Christensen, H., Collins, R., El Etribi, A., Laska, A. C., Lees, K. R., Ozturk, S., Phillips, S., Pocock, S., de Silva, H. A. & 4 others, Szatmari, S., Utton, S., ENOS Trial Investigators & Dennis, M., 14 Feb 2015, In : The Lancet. 385, 9968, p. 617-28 12 p.

    Research output: Contribution to journalArticle

  336. Morphometric Measurements of the Retinal Vasculature in Fundus Images with Vampire

    Trucco, E., Giachetti, A., Ballerini, L., Relan, D., Cavinato, A. & MacGillivray, T., 13 Feb 2015, Biomedical Image Understanding: Methods and Applications. Wiley, p. 91-111 21 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  337. Cigarette smoking and thinning of the brain's cortex

    Karama, S., Ducharme, S., Corley, J., Chouinard-Decorte, F., Starr, J., Wardlaw, J., Bastin, M. & Deary, I., 10 Feb 2015, In : Molecular Psychiatry. 20, p. 778–785

    Research output: Contribution to journalArticle

  338. Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

    Holland, P. R., Pannozzo, M. A., Bastin, M. E., McNeilly, A. D., Ferguson, K. J., Caughey, S., Jansen, M. A., Merrifield, G. D., Marshall, I., Mullins, J. J., Wardlaw, J. M., Sutherland, C. & Horsburgh, K., Feb 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, p. 188-192

    Research output: Contribution to journalArticle

  339. White matter hyperintensities and normal-appearing white matter integrity in the ageing brain

    Munoz-Maniega, S., Valdes Hernandez, M., Clayden, J. D., Royle, N., Murray, C., Morris, Z., Aribisala, B., Gow, A., Starr, J., Bastin, M., Deary, I. & Wardlaw, J., Feb 2015, In : Neurobiology of Aging. 36, 2, p. 909-918

    Research output: Contribution to journalArticle

  340. Automated segmentation of multifocal basal ganglia T2*-weighted MRI hypointensities

    Glatz, A., Bastin, M., Kiker, AJ., Deary, I., Wardlaw, J. & Hernandez, M. D. C. V., 15 Jan 2015, In : NeuroImage. 105, p. 332-346 15 p.

    Research output: Contribution to journalArticle

  341. Influence of Intracerebral Hemorrhage Location on Incidence, Characteristics, and Outcome: Population-Based Study

    Samarasekera, N., Fonville, A., Lerpiniere, C., Farrall, A. J., Wardlaw, J. M., White, P. M., Smith, C., Al-Shahi Salman, R. & for the Lothian Audit of the Treatment of Cerebral Haemorrhage Collaborators, 13 Jan 2015, In : Stroke. 46, p. 361-368

    Research output: Contribution to journalArticle

  342. Performance characteristics of methods for quantifying spontaneous intracerebral haemorrhage: data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial

    Krishnan, K., Mukhtar, S. F., Lingard, J., Houlton, A., Walker, E., Jones, T., Sprigg, N., Dineen, R. A., Koumellis, P., Adami, A., Casado, A., Bath, P. M. W. & Wardlaw, J., 9 Jan 2015, In : Journal of Neurology, Neurosurgery & Psychiatry. 86, p. 1258-1266

    Research output: Contribution to journalArticle

  343. Relational and conjunctive binding functions dissociate in short-term memory

    Parra, M. A., Fabi, K., Luzzi, S., Cubelli, R., Valdes Hernandez, M. & Della Sala, S., 2 Jan 2015, In : Neurocase. 21, 1, p. 56-66 11 p.

    Research output: Contribution to journalArticle

  344. Exploratory analysis of dietary intake and brain iron accumulation detected using magnetic resonance imaging in older individuals: the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Allan, J., Glatz, A., Kyle, J., Corley, J., Brett, C., Munoz-Maniega, S., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Jan 2015, In : The Journal of Nutrition, Health & Aging. 19, 1, p. 64-69

    Research output: Contribution to journalArticle

  345. Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial

    The IST-3 Collaborative Group , Jan 2015, In : Neuroradiology. 57, 1, p. 1-9 9 p.

    Research output: Contribution to journalArticle

  346. Sensitivity and specificity of the Hyperdense Artery Sign for arterial obstruction in acute ischemic stroke

    Mair, G., Boyd, E., Chappell, F., von Kummer, R., Lindley, R., Sandercock, P., Wardlaw, J. & IST-3 Collaborative Group, Jan 2015, In : Stroke. 46, 1, p. 102-107 6 p.

    Research output: Contribution to journalArticle

  347. A comparison of location of acute symptomatic versus 'silent' small vessel lesions

    Valdes Hernandez, M., Maconick, L. C., Munoz-Maniega, S., Wang, X., Wiseman, S., Armitage, P., Doubal, F., Makin, S., Sudlow, C., Dennis, M., Deary, I., Bastin, M. & Wardlaw, J., 2015, In : International Journal of Stroke. 10, p. 1044–1050

    Research output: Contribution to journalArticle

  348. Brain white matter structure and information processing speed in healthy older age

    Kuznetsova, K., Munoz-Maniega, S., Ritchie, S., Cox, S., Storkey, A., Starr, J., Wardlaw, J., Deary, I. & Bastin, M., 2015, In : Brain Structure and Function. 21, 6, p. 3323-3235

    Research output: Contribution to journalArticle

  349. Finding a small subset of relevant features for the classification of retinal vessels

    Barbieri, M., Barla, A., Relan, D., MacGillivray, T., Ballerini, L. & Trucco, E., 2015, Proc. SICSA Dundee Medical Analysis Workshop.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  350. Genes from a translational analysis support a multifactorial nature of white matter hyperintensities

    Lopez, L., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz-Maniega, S., Bastin, M., Bailey, E. L., Smith, C., McBride, M. W., Mcclure, J. D., Graham, D., Dominiczak, A. F., Yang, Q., Fornage, M., Ikfram, MA., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S. & 4 others, Porteous, D., Starr, J., Deary, I. & Wardlaw, J., 2015, In : Stroke. 46, 2, p. 341-347 7 p.

    Research output: Contribution to journalArticle

  351. Hierarchical Classification of Ten Skin Lesion Classes

    Di Leo, C., Bevilacqua, V., Ballerini, L., Fisher, R., Aldridge, B. & Rees, J., 2015, Proc. SICSA Dundee Medical Image Analysis Workshop. 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  352. Intracranial carotid calcification on cranial computed tomography: visual scoring methods, semiautomated scores, and volume measurements in patients with stroke

    Subedi, D., Zishan, U. M., Chappell, F., Gregoriades, M. L., Sudlow, C., Sellar, R. & Wardlaw, J., 2015, In : Stroke. 46, p. 2504-2509

    Research output: Contribution to journalArticle

  353. Morphometric Retinal Measurements With Ultra-Wide-Field-Of-View Imaging

    Pellegrini, E., Robertson, G., Ballerini, L., Pearson, T., MacGillivray, TJ. & Trucco, E., 2015, International Conference on Computational and Mathematical Biomedical Engineering.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  354. Neural mechanisms of Trail Making Test performance

    MacPherson, S. E., Cox, S., Aribisala, B., Bastin, M., Wardlaw, J. & Deary, I., 2015, (Unpublished).

    Research output: Contribution to conferencePaper

  355. Structural brain MRI trait polygenic score prediction of cognitive abilities

    Generation Scotland & SINAPSE Collaborative Grp, 2015, In : Twin Research and Human Genetics. 18, p. 738-745 8 p.

    Research output: Contribution to journalArticle

  356. Textural Characterization on Regions of Interest: A Useful Tool for the Study of Small Vessel Disease

    Viksne, L., Valdes Hernandez, M., Hoban, K., Heye, A. K., Gonzalez-Castro, V. & Wardlaw, J., 2015, Proceedings of the 19th Conference on Medical Image Understanding and Analysis. p. 66-71 6 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  357. Thrombectomy for acute ischaemic stroke

    Wardlaw, J. & Dennis, M., 2015, In : JAMA: the Journal of the American Medical Association. 314, p. 1803-1805

    Research output: Contribution to journalEditorial

  358. Total MRI load of cerebral small vessel disease and cognitive ability in older people

    Staals, J., Booth, T., Morris, Z., Bastin, M., Gow, A., Corley, J., Redmond, P., Starr, J., Deary, I. & Wardlaw, J., 2015, In : Neurobiology of Aging. 36, p. 2806-2811

    Research output: Contribution to journalArticle

  359. VAMPIRE: Vessel Assessment and Measurement Platform for Images of the REtina

    Trucco, E., Annunziata, R., Ballerini, L., Pellegrini, E., McKenna, S., MacGillivray, T., Pearson, T., Relan, D., Robertson, G. & Doney, A., 2015, Proc. SICSA Dundee Medical Image Analysis Workshop.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  360. 2014
  361. Cerebral small vessel disease and renal function: systematic review and meta-analysis

    Makin, S., Cook, F. A. B., Dennis, M. & Wardlaw, J., 24 Dec 2014, In : Cerebrovascular diseases. 39, 1, p. 39-52

    Research output: Contribution to journalArticle

  362. Recommendations From the International Stroke Genetics Consortium, Part 1: Standardized Phenotypic Data Collection

    Majersik, J. J., Cole, J. W., Golledge, J., Rost, N. S., Chan, Y-F. Y., Gurol, M. E., Lindgren, A. G., Woo, D., Fernandez-Cadenas, I., Chen, D. T., Thijs, V., Worrall, B. B., Kamal, A., Bentley, P., Wardlaw, J. M., Ruigrok, Y. M., Battey, T. W. K., Schmidt, R., Montaner, J., Giese, A-K. & 8 others, Roquer, J., Jiménez-Conde, J., Lee, C., Ay, H., Martin, J. J., Rosand, J., Maguire, J. & on behalf of the International Stroke Genetics Consortium, 9 Dec 2014, In : Stroke; a journal of cerebral circulation. 46, p. 279-84

    Research output: Contribution to journalArticle

  363. Effect of Alteplase Within 6 Hours of Acute Ischemic Stroke on All-Cause Mortality (Third International Stroke Trial)

    Whiteley, W. N., Thompson, D., Murray, G., Cohen, G., Lindley, R. I., Wardlaw, J., Sandercock, P. & IST-3 Collaborative Grp, Dec 2014, In : Stroke. 45, 12, p. 3612-3617 6 p.

    Research output: Contribution to journalArticle

  364. Personality, Health, and Brain Integrity: The Lothian Birth Cohort Study 1936

    Booth, T., Mõttus, R., Corley, J., Gow, A. J., Henderson, R. D., Munoz-Maniega, S., Murray, C., Royle, N. A., Sprooten, E., Hernández, M. C. V., Bastin, M. E., Penke, L., Starr, J. M., Wardlaw, J. M. & Deary, I. J., Dec 2014, In : Health Psychology. 33, 12, p. 1477-1486 10 p.

    Research output: Contribution to journalArticle

  365. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

    Emberson, J., Lees, K. R., Lyden, P., Blackwell, L., Albers, G., Bluhmki, E., Brott, T., Cohen, G., Davis, S., Donnan, G., Grotta, J., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M., Lindley, R. I., Murray, G., Olivot, J. M., Parsons, M. & 11 others, Tilley, B., Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., Whiteley, W., Del Zoppo, G. J., Baigent, C., Sandercock, P., Hacke, W. & for the Stroke Thrombolysis Trialists' Collaborative Group, 29 Nov 2014, In : The Lancet. 384, 9958, p. 1929-1935

    Research output: Contribution to journalArticle

  366. Stroke subtype, vascular risk factors and total MRI brain small vessel disease burden

    Staals, J., Makin, S., Doubal, F., Dennis, M. & Wardlaw, J., 30 Sep 2014, In : Neurology. 83, 14, p. 1228-1234

    Research output: Contribution to journalArticle

  367. Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden

    Staals, J., Makin, S. D. J., Doubal, F. N., Dennis, M. S. & Wardlaw, J. M., 30 Sep 2014, In : Neurology. 83, 14, p. 1228-1234 7 p.

    Research output: Contribution to journalArticle

  368. Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?

    Lyall, D. M., Harris, S. E., Bastin, M. E., Munoz-Maniega, S., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Valdés Hernández, M., Royle, N. A., Starr, J. M., Porteous, D. J., Wardlaw, J. M. & Deary, I. J., 23 Sep 2014, In : Translational Psychiatry. 4, 9, 7 p., e449.

    Research output: Contribution to journalArticle

  369. Assessment of blood-brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review

    Heye, A. K., Culling, R. D., Valdes Hernandez, M., Thrippleton, M. J. & Wardlaw, J. M., 10 Sep 2014, In : NeuroImage: Clinical. 6, p. 262–274

    Research output: Contribution to journalArticle

  370. Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing

    Aribisala, B. S., Royle, N. A., Valdés Hernández, M. C., Murray, C., Penke, L., Gow, A., Munoz-Maniega, S., Starr, J. M., Bastin, M., Deary, I. & Wardlaw, J., Sep 2014, In : Age and Ageing. 43, 5, p. 712-716 5 p.

    Research output: Contribution to journalArticle

  371. Alteplase for ischaemic stroke--responses

    Sandercock, P., Lindley, R., Wardlaw, J. M., Murray, G., Whiteley, W. & Cohen, G., 23 Aug 2014, In : The Lancet. 384, 9944, p. 660-1 2 p.

    Research output: Contribution to journalArticle

  372. Baseline characteristics of the 4011 patients recruited into the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial

    Bath, P. M. W., Adami, A., Bereczki, D., Berge, E., Beridze, M., Cala, L., Casado, A., Caso, V., Chang, H. M., Christensen, H., Collins, R., Czlonkowska, A., Dineen, R. A., El Etribi, A., Ghani, A. R., Gommans, J., Koumellis, P., Laska, A. C., Lees, K. R., Navarro, J. & 17 others, Ntaios, G., Ozturk, S., Phillips, S., Pocock, S., Prasad, K., Scutt, P., de Silva, H. A., Szatmari, S., Diez-Tejedor, E., Utton, S., Wang, Y-J., Wardlaw, J. M., Whynes, D., Wong, L., Woodhouse, L., Sprigg, N. & ENOS Investigators, Aug 2014, In : International Journal of Stroke. 9, 6, p. 711-720 10 p.

    Research output: Contribution to journalArticle

  373. Imaging of acute stroke prior to treatment: current practice and evolving techniques

    Mair, G. & Wardlaw, J., Aug 2014, In : British Journal of Radiology. 87, 1040, 14 p., 20140216.

    Research output: Contribution to journalLiterature review

  374. Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling

    Kochunov, P., Jahanshad, N., Sprooten, E., Nichols, T. E., Mandl, R. C., Almasy, L., Booth, T., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Dimitrova, R., Duggirala, R., Fox, P. T., Elliot Hong, L., Landman, B. A., Lemaitre, H., Lopez, L., Martin, N. G., McMahon, K. L., Mitchell, B. D. & 21 others, Olvera, R. L., Peterson, C. P., Starr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Wright, S. N., Bastin, M. E., McIntosh, A. M., Boomsma, D. I., Kahn, R. S., den Braber, A., de Geus, E. J. C., Deary, I. J., Hulshoff Pol, H. E., Williamson, D. E., Blangero, J., van 't Ent, D., Thompson, P. M. & Glahn, D. C., 15 Jul 2014, In : NeuroImage. 95, p. 136-150 15 p.

    Research output: