Edinburgh Research Explorer

The Queens Medical Research Institute

Organisational unit: Research Institute

  1. 11 beta-hydroxysteroid dehydrogenases in the brain - Two enzymes two roles

    Holmes, M. C., Yau, J. L. W., Kotelevtsev, Y., Mullins, J. J. & Seckl, J. R., 2003, STEROIDS AND THE NERVOUS SYSTEM. Panzica, G. & Melcangi, RC. (eds.). NEW YORK: New York Academy of Sciences, p. 357-366 10 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  2. 11-Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors in type 2 diabetes mellitus and obesity

    Hughes, K. A., Webster, S. P. & Walker, B. R., Apr 2008, In: Expert opinion on investigational drugs. 17, 4, p. 481-96 16 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  3. 11Beta-hydroxysteroid dehydrogenase type 1--a role in inflammation?

    Chapman, K. E., Gilmour, J. S., Coutinho, A. E., Savill, J. S. & Seckl, J. R., 2006, In: Molecular and Cellular Endocrinology. 248, 1-2, p. 3-8 6 p.

    Research output: Contribution to journalArticlepeer-review

  4. 11Beta-hydroxysteroid dehydrogenases in human endometrium

    McDonald, S. E., Henderson, T. A., Gomez-Sanchez, C. E., Critchley, H. O. D. & Mason, J. I., 2006, In: Molecular and Cellular Endocrinology. 248, 1-2, p. 72-8 7 p.

    Research output: Contribution to journalArticlepeer-review

  5. 11beta-HSD1(-/-) mice escape severe adipose tissue fibrosis by up-regulating angiogenic responses under obesogenic conditions

    Michailidou, Z., Iredale, J., Morton, N. & Seckl, J., Oct 2010, In: Diabetes Obesity & Metabolism. 12, p. 44-44 1 p.

    Research output: Contribution to journalArticlepeer-review

  6. 11beta-HSD1, inflammation, metabolic disease and age-related cognitive (dys)function

    Chapman, K. E. & Seckl, J. R., Apr 2008, In: Neurochemical Research. 33, 4, p. 624-636 13 p.

    Research output: Contribution to journalArticlepeer-review

  7. 11beta-Hydroxysteroid dehydrogenase type 2 protects the neonatal cerebellum from deleterious effects of glucocorticoids

    Holmes, M. C., Sangra, M., French, K. L., Whittle, I. R., Paterson, J., Mullins, J. J. & Seckl, J. R., 2006, In: Neuroscience. 137, 3, p. 865-873 9 p.

    Research output: Contribution to journalArticlepeer-review

  8. 11beta-hydroxysteroid dehydrogenase-1 plays a key role in hypothalamo-pituitary arenal axis regulation.

    Holmes, M. C., Harris, H. J., Kotelevtsev, Y., Mullins, J. J. & Seckl, J. R., 2000, In: European Journal of Neuroscience. 12, p. 415-415 1 p.

    Research output: Contribution to journalArticlepeer-review

  9. 11β-HSD1 inhibitors for the treatment of type 2 diabetes and cardiovascular disease

    Anderson, A. & Walker, B. R., Sep 2013, In: Drugs. 73, 13, p. 1385-1393 9 p.

    Research output: Contribution to journalArticlepeer-review

  10. 11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

    Mylonas, K. J., Turner, N. A., Bageghni, S. A., Kenyon, C. J., White, C. I., McGregor, K., Kimmitt, R. A., Sulston, R., Kelly, V., Walker, B. R., Porter, K. E., Chapman, K. E. & Gray, G. A., 1 Jun 2017, In: Journal of Endocrinology. 233, 3, p. 315-327 13 p.

    Research output: Contribution to journalArticlepeer-review

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