Edinburgh Research Explorer

The Queens Medical Research Institute

Organisational unit: Research Institute

  1. 2020
  2. Not a cute stroke: Analysis of Rule- and Neural Network-based Information Extraction Systems for Brain Radiology Reports

    Grivas, A., Alex, B., Grover, C., Tobin, RICHARD. & Whiteley, W., 20 Nov 2020, Proceedings of the 11th International Workshop on Health Text Mining and Information Analysis. Association for Computational Linguistics, p. 24–37 14 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  3. Establishment of a novel human fetal adrenal culture model that supports de novo and manipulated steroidogenesis

    Melau, C., Nielsen, J. E., Perlman, S., Lundvall, L., Thuesen, L. L., Hare, K. J., Hammerum, M. S., Frederiksen, H., Mitchell, R. T., Juul, A. & Jørgensen, A., 19 Nov 2020, In : Journal of Clinical Endocrinology & Metabolism.

    Research output: Contribution to journalArticle

  4. Target-inhibition of Galectin-3 by Inhaled TD139 in Patients with Idiopathic Pulmonary Fibrosis

    Hirani, N., Mackinnon, A., Nicol, L., Ford, P., Schambye, H., Pedersen, A., Nilsson, U. J., Leffler, H., Sethi, T., Tantawi, S., Gavelle, L., Slack, R. J., Mills, R., Karmakar, U., Humphries, D., Zetterberg, F., Keeling, L., Paul, L., Molyneaux, P. L., Li, F. & 5 others, Funston, W., Forrest, I. A., Simpson, A. J., Gibbons, M. A. & Maher, T. M., 19 Nov 2020, In : European Respiratory Journal.

    Research output: Contribution to journalArticle

  5. Comparison of Rule-based and Neural Network Models for Negation Detection in Radiology Reports

    Sykes, D., Grivas, A., Grover, C., Tobin, RICHARD., Sudlow, C., Whiteley, W., McIntosh, A., Whalley, H. & Alex, B., 18 Nov 2020, In : Natural Language Engineering. 22 p.

    Research output: Contribution to journalArticle

  6. Cognitive dispersion and ApoEe4 genotype predict dementia diagnosis in 8-year follow-up of the oldest-old

    Watermeyer, T., Goerdten, J., Johansson, B. & Muniz-terrera, G., 14 Nov 2020, In : Age and Ageing.

    Research output: Contribution to journalArticle

  7. Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta-analysis

    Hamilton, O., Backhouse, E., Janssen, E., Jochems, A., Maher, C., Ritakari, T., Stevenson, A., Xia, L., Deary, I. & Wardlaw, J., 13 Nov 2020, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  8. Economic Evaluation of GPs’ Direct Access to Computed Tomography for Identification of Brain Tumours

    Keeney, E., Mohiuddin, S., Zienius, K., Ben-shlomo, Y., Ozawa, M., Grant, R., Hamilton, W., Weller, D., Brennan, P. & Hollingworth, W., 13 Nov 2020, In : European Journal of Cancer Care.

    Research output: Contribution to journalArticle

  9. The Synapse in Traumatic Brain Injury

    Jamjoom, A., Rhodes, J. K. J., Andrews, P. & Grant, S., 13 Nov 2020, In : Brain.

    Research output: Contribution to journalArticle

  10. A systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis

    Cunniffe, N., Vuong, K. A., Ainslie, D., Baker, D., Beveridge, J., Bickley, S. R. B., Camilleri, P., Craner, M., Fitzgerald, D. C., De La Fuente, A. G., Giovannoni, G., Gray, E., Hazlehurst, L., Kapoor, R., Kaur, R., Kozlowski, D., Lumicisi, B., Mahad, D., Neumann, B., Palmer, A. & 9 others, Peruzzotti-Jametti, L., Pluchino, S., Robertson, J., Rothaul, A., Shellard, L., Smith, K. J., Wilkins, A., Williams, A. C. & Coles, A. J., 12 Nov 2020, In : Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journalArticle

  11. Artificial Intelligence, speech and language processing approaches to monitoring Alzheimer's Disease: a systematic review

    De La Fuente Garcia, S., Ritchie, C. & Luz, S., 12 Nov 2020, In : Journal of Alzheimer's Disease. 56 p.

    Research output: Contribution to journalArticle

  12. Decoding myofibroblast origins in human kidney fibrosis

    Kuppe, C., Ibrahim, M. M., Kranz, J., Zhang, X., Ziegler, S., Perales-patón, J., Jansen, J., Reimer, K. C., Smith, J. R., Dobie, R., Wilson-Kanamori, J. R., Halder, M., Xu, Y., Kabgani, N., Kaesler, N., Klaus, M., Gernhold, L., Puelles, V. G., Huber, T. B., Boor, P. & 9 others, Menzel, S., Hoogenboezem, R. M., Bindels, E. M. J., Steffens, J., Floege, J., Schneider, R. K., Saez-rodriguez, J., Henderson, N. C. & Kramann, R., 11 Nov 2020, In : Nature.

    Research output: Contribution to journalArticle

  13. Diagnostic accuracy of the 4AT for delirium detection in older adults: systematic review and meta-analysis.

    Tieges, Z., Maclullich, A. M. J., Anand, A., Brookes, C., Cassarino, M., O'Connor, M., Ryan, D., Saller, T., Arora, R. C., Chang, Y., Agarwal, K., Taffet, G., Quinn, T., Shenkin, S. D. & Galvin, R., 11 Nov 2020, In : Age and Ageing.

    Research output: Contribution to journalLiterature review

  14. “Scan-negative” cauda equina syndrome: A prospective cohort study

    Hoeritzauer, I., Carson, A., Statham, P., Panicker, J. N., Granitsiotis, V., Eugenicos, M., Summers, D., Demetriades, A. K. & Stone, J., 11 Nov 2020, In : Neurology. p. 10.1212/WNL.0000000000011154

    Research output: Contribution to journalArticle

  15. Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH): protocol for a phase II double-blind randomised controlled feasibility trial

    J R Desborough, M., Al-Shahi Salman, R., Stanworth, S. J., Havard, D., Brennan, P., Dineen, R. A., Coats, T. J., Hepburn, T., Bath, P. M. & Sprigg, N., 10 Nov 2020, In : BMJ Open.

    Research output: Contribution to journalArticle

  16. An ecological momentary assessment study of the role of emotional dysregulation in co-occurring ADHD and internalising symptoms in adulthood

    Murray, A. L., Wong, S-C., Obsuth, I., Rhodes, S., Eisner, M. & Ribeaud, D., 9 Nov 2020, (Accepted/In press) In : Journal of affective disorders.

    Research output: Contribution to journalArticle

  17. Prediction of depression symptoms in individual subjects with face and eye movement tracking

    Stolicyn, A., Steele, J. D. & Series, P., 9 Nov 2020, In : Psychological Medicine. 29 p.

    Research output: Contribution to journalArticle

  18. The UK needs a sustainable strategy for COVID-19

    Gurdasani, D., Bear, L., Bogaert, D., Burgess, R. A., Busse, R., Cacciola, R., Charpak, Y., Colbourn, T., Drury, J., Friston, K., Gallo, V., Goldman, L. R., Greenhalgh, T., Hyde, Z., Kuppalli, K., Majumder, M. S., Martin-moreno, J. M., Mckee, M., Michie, S., Mossialos, E. & 17 others, Nouri, A., Pagel, C., Pimenta, D., Popescu, S., Priesemann, V., Rasmussen, A. L., Reicher, S., Ricciardi, W., Rice, K., Silver, J., Smith, T. C., Wenham, C., West, R., Yamey, G., Yates, C., Ziauddeen, H. & Cameron, D. A., 9 Nov 2020, In : The Lancet.

    Research output: Contribution to journalLetter

  19. The impact of bilingualism on the executive functions of autistic children: A study of English-Arabic children

    Sharaan, S., Fletcher-Watson, S. & MacPherson, S. E., 9 Nov 2020, (Accepted/In press) In : Autism Research.

    Research output: Contribution to journalArticle

  20. Neuroepidemiology of human prion disease

    Urwin, P. & Molesworth, A., 7 Nov 2020, Oxford Textbook of Neurological and Neuropsychiatric Epidemiology. Brayne, C., Feigin, V., Launer, L. J. & Logroscino, G. (eds.). Oxford University Press

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  21. Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD

    Orrú, C. D., Groveman, B. R., Foutz, A., Bongianni, M., Cardone, F., Mckenzie, N., Culeux, A., Poleggi, A., Grznarova, K., Perra, D., Fiorini, M., Liu, X., Ladogana, A., Sbriccoli, M., Hughson, A. G., Haïk, S., Green, A. J., Geschwind, M. D., Pocchiari, M., Safar, J. G. & 2 others, Zanusso, G. & Caughey, B., 7 Nov 2020, In : Annals of Clinical and Translational Neurology. 7, 11, p. 2262-2271

    Research output: Contribution to journalArticle

  22. The mRNA m6A reader YTHDF2 supresses pro-inflammatory pathways and sustains hematopoietic stem cell function

    Mapperley, C., Van De Lagemaat, L., Lawson, H., Tavosanis, A., Paris, J., Campos, J., Wotherspoon, D., Durko, J., Sarapuu, A., Junho, C., Ivanova, I., Krause, D. S., von Kriegsheim, A., Much, C., Morgan, M., Gregory, R. I., Mead, A. J., O'Carroll, D. & Kranc, K., 6 Nov 2020, In : Journal of Experimental Medicine. 218, 3, 11 p., e20200829.

    Research output: Contribution to journalArticle

  23. Glioblastoma post-operative imaging in neuro-oncology: current UK practice (GIN CUP study)

    Booth, T. C., Luis, A., Brazil, L., Thompson, G., Daniel, R. A., Shuaib, H., Ashkan, K. & Pandey, A., 5 Nov 2020, In : European Radiology.

    Research output: Contribution to journalArticle

  24. Multi-layered spatial transcriptomics identify secretory factors promoting hematopoietic stem cell emergence in human development

    Crosse, E., Gordon-Keylock, S., Rybtsov, S., Binagui-Casas, A., Felchle, H., Nnadi, N., Kirschner, K., Chandra, T., Tamagno, S., Webb, D. J., Rossi, F., Anderson, R. A. & Medvinsky, A., 5 Nov 2020, In : Cell Stem Cell. 27, 5, p. 822-839.e8

    Research output: Contribution to journalArticle

  25. N-acetyl aspartate (NAA) is a marker of disability in secondary progressive multiple sclerosis: a proton magnetic resonance spectroscopic imaging study

    MS-SMART Investigators, 5 Nov 2020, In : American Journal of Neuroradiology.

    Research output: Contribution to journalArticle

  26. Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial

    Beishon, L., Woodhouse, L. J., Bereczki, D., Christensen, H. K., Collins, R., Gommans, J., Kruuse, C., Ntaios, G., Ozturk, S., Phillips, S., Pocock, S., Szatmari, S., Wardlaw, J., Sprigg, N. & Bath, P. M., 5 Nov 2020, In : Stroke and Vascular Neurology. p. svn-2020-000498

    Research output: Contribution to journalArticle

  27. Nanopore Sequencing Enables Comprehensive Transposable Element Epigenomic Profiling

    Ewing, A. D., Smits, N., Sanchez-luque, F. J., Faivre, J., Brennan, P. M., Richardson, S. R., Cheetham, S. W. & Faulkner, G. J., 4 Nov 2020, In : Molecular Cell.

    Research output: Contribution to journalArticle

  28. Reduction of environmental pollutants for prevention of cardiovascular disease: it’s time to act

    Münzel, T., Miller, M. R., Sorensen, M., Lelieveld, J., Daiber, A. & Rajagopalan, S., 3 Nov 2020, In : European Heart Journal.

    Research output: Contribution to journalArticle

  29. The association between CT biomarkers of cerebral small vessel diseases and long‐term outcome after spontaneous intracerebral hemorrhage

    Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators, 3 Nov 2020, In : Annals of Neurology.

    Research output: Contribution to journalArticle

  30. Do I lose cognitive function as fast as my twin partner? Analyses based on classes of MMSE trajectories of twins aged 80 and older

    Muniz-terrera, G., Robitaille, A., Goerdten, J., Massa, F. & Johansson, B., 31 Oct 2020, In : Age and Ageing.

    Research output: Contribution to journalArticle

  31. Polypharmacy and emergency readmission to hospital after critical illness: a population-level cohort study

    Turnbull, A., Donaghy, E., Salisbury, L., Ramsay, P., Rattray, J., Walsh, T. S. & Lone, N. I., 31 Oct 2020, In : British Journal of Anaesthesia.

    Research output: Contribution to journalArticle

  32. Spotlight on microRNAs in allergy and asthma

    Weidner, J., Bartel, S., Kılıç, A., Zissler, U. M., Renz, H., Schwarze, J., Schmidt‐weber, C. B., Maes, T., Rebane, A., Krauss‐etschmann, S. & Rådinger, M., 31 Oct 2020, In : Allergy.

    Research output: Contribution to journalReview article

  33. Conventional and Genetic Evidence on the Association between Adiposity and CKD

    Zhu, P., Herrington, W. G., Haynes, R., Emberson, J., Landray, M. J., Sudlow, C. L. M., Woodward, M., Baigent, C., Lewington, S. & Staplin, N., 30 Oct 2020, In : Journal of the American Society of Nephrology.

    Research output: Contribution to journalArticle

  34. Feasibility and diagnostic accuracy of using brain attenuation changes on CT to estimate time of ischemic stroke onset

    Mair, G., Alzahrani, A., Lindley, R. I., Sandercock, P. A. G. & Wardlaw, J. M., 30 Oct 2020, In : Neuroradiology.

    Research output: Contribution to journalArticle

  35. Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury

    MacFarlane, J. G., Dorward, D. A., Ruchaud-Sparagano, M-H., Scott, J., Lucas, C. D., Rossi, A. G. & Simpson, A. J., 30 Oct 2020, In : Journal of inflammation.

    Research output: Contribution to journalArticle

  36. Epidemiology of university American Football injuries in the United Kingdom

    Bayram, J., Hamilton, D. & Saunders, D., 29 Oct 2020, In : Orthopaedic journal of sports medicine. 24 p.

    Research output: Contribution to journalArticle

  37. Innate immune training of granulopoiesis promotes anti-tumor activity

    Kalafati, L., Kourtzelis, I., Schulte-Schrepping, J., Li, X., Hatzioannou, A., Grinenko, T., Hagag, E., Sinha, A., Has, C., Dietz, S., de Jesus Domingues, A. M., Nati, M., Sormendi, S., Neuwirth, A., Chatzigeorgiou, A., Ziogas, A., Lesche, M., Dahl, A., Henry, I., Subramanian, P. & 10 others, Wielockx, B., Murray, P., Mirtschink, P., Chung, K., Schultze, J. L., Netea, M. G., Hajishengallis, G., Verginis, P., Mitroulis, I. & Chavakis, T., 29 Oct 2020, In : Cell. 183, 3, p. 771-785

    Research output: Contribution to journalArticle

  38. Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety

    Zafeiri, A., Mitchell, R. T., Hay, D. C. & Fowler, P., 29 Oct 2020, In : Human Reproduction Update.

    Research output: Contribution to journalArticle

  39. Reporting incidental coronary, aortic valve and cardiac calcification on non-gated thoracic computed tomography, a consensus statement from the BSCI/BSCCT and BSTI

    Williams, M. C., Abbas, A., Tirr, E., Alam, S., Nicol, E., Shambrook, J., Schmitt, M., Morgan-Hughes, G. J., Stirrup, J., Holloway, B., Gopalan, D., Deshpande, A., Weir-McCall, J., Agrawal, B., Rodrigues, J. C. L., Brady, A. J. B., Roditi, G., Robinson, G. & Bull, R., 29 Oct 2020, In : British Journal of Radiology.

    Research output: Contribution to journalArticle

  40. Development of a cost effective automated platform to produce human liver spheroids for basic and applied research

    Lucendo-Villarin, B., Meseguer Ripolles, J., Drew, J., Fisher, L., Ma, E., Flint, O., Simpson, K. J., Machesky, L. M., Mountford, J. C. & Hay, D. C., 28 Oct 2020, In : Biofabrication.

    Research output: Contribution to journalArticle

  41. Risk of hospital admission with coronavirus disease 2019 in healthcare workers and their households: nationwide linkage cohort study

    Shah, A. S. V., Wood, R., Gribben, C., Caldwell, D., Bishop, J., Weir, A., Kennedy, S., Reid, M., Smith-Palmer, A., Goldberg, D., McMenamin, J., Fischbacher, C., Robertson, C., Hutchinson, S., McKeigue, P., Colhoun, H. & McAllister, D. A., 28 Oct 2020, In : BMJ (Clinical research ed.). 371, p. m3582

    Research output: Contribution to journalArticle

  42. Phosphorylation of NANOG by CASEIN KINASE I regulates embryonic stem cell self-renewal

    Mullin, N. P., Varghese, J., Colby, D., Richardson, J. M., Findlay, G. M. & Chambers, I., 26 Oct 2020, In : FEBS Letters.

    Research output: Contribution to journalArticle

  43. The Importance of Engaging in Physical Activity in Older Adulthood for Transitions between Cognitive Status Categories and Death: A Coordinated Analysis of Fourteen Longitudinal Studies

    Yoneda, T., Lewis, N. A., Knight, J. E., Rush, J., Vendittelli, R., Kleineidam, L., Hyun, J., Piccinin, A. M., Hofer, S. M., Hoogendijk, E. O., Derby, C. A., Scherer, M., Riedel-heller, S., Wagner, M., Van Den Hout, A., Wang, W., Bennett, D. A. & Muniz-terrera, G., 25 Oct 2020, In : Journals of Gerontology, Series A.

    Research output: Contribution to journalArticle

  44. Diagnosis of COVID-19 by analysis of breath with gas chromatography-ion mobility spectrometry - a feasibility study

    Ruszkiewicz, D. M., Sanders, D., O'Brien, R., Hempel, F., Reed, M. J., Riepe, A. C., Bailie, K., Brodrick, E., Darnley, K., Ellerkmann, R., Mueller, O., Skarysz, A., Truss, M., Wortelmann, T., Yordanov, S., Thomas, C. L. P., Schaaf, B. & Eddleston, M., 24 Oct 2020, In : EClinicalMedicine. p. 100609

    Research output: Contribution to journalArticle

  45. Diagnosis of COVID-19 by analysis of breath with gas chromatographyion mobility spectrometry - a feasibility study

    Ruszkiewicz, D. M., Sanders, D., O’Brien, R., Hempel, F., Reed, M. J., Riepe, A. C., Baillie, J. K., Brodrick, E., Darnley, K., Ellerkmann, R., Mueller, O., Skarysz, A., Truss, M., Wortelmann, T., Yordanov, S., Thomas, C. L. P., Schaaf, B. & Eddleston, M., 24 Oct 2020, In : EClinicalMedicine.

    Research output: Contribution to journalArticle

  46. DiCyc: GAN-based deformation invariant cross-domain information fusion for medical image synthesis

    Wang, C., Yang, G., Papanastasiou, G., Tsaftaris, S. A., Newby, D. E., Gray, C., Macnaught, G. & MacGillivray, T., 23 Oct 2020, In : International Journal of Information Fusion.

    Research output: Contribution to journalArticle

  47. Hybrid Learning based Cell Aggregate Imaging with Miniature Electrical Impedance Tomography

    Chen, Z., Yang, Y. & Bagnaninchi, P. O., 23 Oct 2020, (Accepted/In press) In : IEEE Transactions on Instrumentation and Measurement.

    Research output: Contribution to journalArticle

  48. Outcomes of COVID-19 related hospitalization among people with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): a prospective observational study

    Geretti, A. M., Stockdale, A. J., Kelly, S. H., Cevik, M., Collins, S., Waters, L., Villa, G., Docherty, A., Harrison, E. M., Turtle, L., Openshaw, P. J. M., Baillie, J. K., Sabin, C. A. & Semple, M. G., 23 Oct 2020, In : Clinical Infectious Diseases.

    Research output: Contribution to journalArticle

  49. PHOSPHO1 is a skeletal regulator of insulin resistance and obesity

    Suchacki, K., Morton, N. M., Vary, C., Huesa, C., Yadav, M., Thomas, B., Turban, S., Bungar, L., Ball, D., Barrios-Llerena, M., Guntur, A., Khavandgar, Z., Cawthorn, W. P., Ferron, M., Karsenty, G., Murshed, M., Rosen, C. J., MacRae, V., Millan, J-L. & Farquharson, C., 22 Oct 2020, In : BMC Biology.

    Research output: Contribution to journalArticle

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