Edinburgh Research Explorer

Abdel Essafi

(Former employee or visitor)

  1. A Wt1-Controlled Chromatin Switching Mechanism Underpins Tissue-Specific Wnt4 Activation and Repression

    Essafi, A., Webb, A., Berry, R. L., Slight, J., Burn, S. F., Spraggon, L., Velecela, V., Martinez-Estrada, O. M., Wiltshire, J. H., Roberts, S. G. E., Brownstein, D., Davies, J. A., Hastie, N. D. & Hohenstein, P., Sep 2011, In: Developmental Cell. 21, 3, p. 559-574 16 p.

    Research output: Contribution to journalArticlepeer-review

  2. Fibroblast growth factors (FGFs) prime the limb specific Shh enhancer for chromatin changes that balance histone acetylation mediated by E26 transformation-specific (ETS) factors

    Peluso, S., Douglas, A., Hill, A., De Angelis, C., Moore, B. L., Grimes, G., Petrovich, G., Essafi, A. & Hill, R. E., 27 Oct 2017, In: eLIFE. 6, 22 p., e28590.

    Research output: Contribution to journalArticlepeer-review

  3. Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling

    Overton, I., Sims, A. H., A. Owen, J., S. E Heale, B., Ford, M. J., Lubbock, A., Pairo-Castineira, E. & Essafi, A., 30 Sep 2020, In: Cancers.

    Research output: Contribution to journalArticlepeer-review

  4. Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation

    Lauc, G., Essafi, A., Huffman, J. E., Hayward, C., Knezevic, A., Kattla, J. J., Polasek, O., Gornik, O., Vitart, V., Abrahams, J. L., Pucic, M., Novokmet, M., Redzic, I., Campbell, S., Wild, S. H., Borovecki, F., Wang, W., Kolcic, I., Zgaga, L., Gyllensten, U. & 6 others, Wilson, J. F., Wright, A. F., Hastie, N. D., Campbell, H., Rudd, P. M. & Rudan, I., Dec 2010, In: PLoS Genetics. 6, 12, p. - 14 p., e1001256.

    Research output: Contribution to journalArticlepeer-review

  5. Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence

    Benko, S., Fantes, J. A., Amiel, J., Kleinjan, D-J., Thomas, S., Ramsay, J., Jamshidi, N., Essafi, A., Heaney, S., Gordon, C. T., McBride, D., Golzio, C., Fisher, M., Perry, P., Abadie, V., Ayuso, C., Holder-Espinasse, M., Kilpatrick, N., Lees, M. M., Picard, A. & 12 others, Temple, I. K., Thomas, P., Vazquez, M-P., Vekemans, M., Roest Crollius, H., Hastie, N. D., Munnich, A., Etchevers, H. C., Pelet, A., Farlie, P. G., Fitzpatrick, D. R. & Lyonnet, S., Mar 2009, In: Nature Genetics. 41, 3, p. 359-364 6 p.

    Research output: Contribution to journalArticlepeer-review

  6. Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile

    Thanabalasingham, G., Huffman, J. E., Kattla, J. J., Novokmet, M., Rudan, I., Gloyn, A. L., Hayward, C., Adamczyk, B., Reynolds, R. M., Muzinic, A., Hassanali, N., Pucic, M., Bennett, A. J., Essafi, A., Polasek, O., Mughal, S. A., Redzic, I., Primorac, D., Zgaga, L., Kolcic, I. & 20 others, Hansen, T., Gasperikova, D., Tjora, E., Strachan, M. W. J., Nielsen, T., Stanik, J., Klimes, I., Pedersen, O. B., Njølstad, P. R., Wild, S. H., Gyllensten, U., Gornik, O., Wilson, J. F., Hastie, N. D., Campbell, H., McCarthy, M. I., Rudd, P. M., Owen, K. R., Lauc, G. & Wright, A. F., Apr 2013, In: Diabetes . 62, 4, p. 1329-1337

    Research output: Contribution to journalArticlepeer-review

  7. Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly

    Lettice, L. A., Williamson, I., Wiltshire, J. H., Peluso, S., Devenney, P. S., Hill, A. E., Essafi, A., Hagman, J., Mort, R., Grimes, G., DeAngelis, C. L. & Hill, R. E., 2012, In: Developmental Cell. 22, 2, p. 459-67 9 p.

    Research output: Contribution to journalArticlepeer-review

  8. WT1 the oncogene: a tale of death and HtrA

    Essafi, A. & Hastie, N. D., 2010, In: Molecular Cell. 37, 2, p. 153-5 3 p.

    Research output: Contribution to journalArticlepeer-review

  9. Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin

    Martínez-Estrada, O. M., Lettice, L. A., Essafi, A., Guadix, J. A., Slight, J., Velecela, V., Hall, E., Reichmann, J., Devenney, P. S., Hohenstein, P., Hosen, N., Hill, R. E., Muñoz-Chapuli, R. & Hastie, N. D., 2010, In: Nature Genetics. 42, 1, p. 89-93 5 p.

    Research output: Contribution to journalArticlepeer-review