Edinburgh Research Explorer

Alastair Kerr

(Former employee or visitor)

  1. Comparative proteomic analyses of the nuclear envelope and pore complex suggests a wide range of heretofore unexpected functions

    Batrakou, D. G., Kerr, A. R. W. & Schirmer, E. C., 2009, In: Journal of proteomics. 72, 1, p. 56-70 15 p.

    Research output: Contribution to journalArticlepeer-review

  2. Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

    Bikkul, M. U., Faragher, R. G. A., Worthington, G., Meinke, P., Kerr, A. R. W., Sammy, A., Riyahi, K., Horton, D., Schirmer, E. C., Hubank, M., Kill, I. R., Anderson, R. M., Slijepcevic, P., Makarov, E. & Bridger, J. M., 1 Jun 2019, In: Genes, Chromosomes and Cancer. 58, 6, p. 341-356 16 p.

    Research output: Contribution to journalArticlepeer-review

  3. The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

    Brown, K., Selfridge, J., Lagger, S., Connelly, J., De Sousa, D., Kerr, A., Webb, S., Guy, J., Merusi, C., Koerner, M. V. & Bird, A., 1 Feb 2016, In: Human Molecular Genetics. 25, 3, p. 558-570

    Research output: Contribution to journalArticlepeer-review

  4. Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells

    Clouaire, T., Webb, S., Skene, P., Illingworth, R., Kerr, A., Andrews, R., Lee, J-H., Skalnik, D. & Bird, A., 1 Aug 2012, In: Genes & Development. 26, 15, p. 1714-1728 15 p.

    Research output: Contribution to journalArticlepeer-review

  5. Co-transcriptional degradation of aberrant pre-mRNA by Xrn2

    Davidson, L., Kerr, A. & West, S., 2012, In: EMBO Journal. 31, 11, p. 2566-2578 13 p.

    Research output: Contribution to journalArticlepeer-review

  6. Cell type--specific DNA methylation at intragenic CpG islands in the immune system

    Deaton, A. M., Webb, S., Kerr, A. R. W., Illingworth, R. S., Guy, J., Andrews, R. & Bird, A., 2011, In: Genome Research. 21, 7, p. 1074-1086 13 p.

    Research output: Contribution to journalArticlepeer-review

  7. A rapid computational approach identifies SPICE1 as an Aurora kinase substrate

    Deretic, J., Kerr, A. & Welburn, J. P. I., 31 Jan 2019, In: Molecular Biology of the Cell. 30, 3, p. 312-323 12 p.

    Research output: Contribution to journalArticlepeer-review

  8. Genome-Wide Distribution of RNA-DNA Hybrids Identifies RNase H Targets in tRNA Genes, Retrotransposons and Mitochondria

    El Hage, A., Webb, S., Kerr, A. & Tollervey, D., 30 Oct 2014, In: PLoS Genetics. 10, 10, e1004716.

    Research output: Contribution to journalArticlepeer-review

  9. Structural evidence for Scc4-dependent localization of cohesin loading

    Hinshaw, S. M., Makrantoni, V., Kerr, A., Marston, A. L. & Harrison, S. C., 3 Jun 2015, In: eLIFE. 4, JUNE, 15 p., e06057.

    Research output: Contribution to journalArticlepeer-review

  10. Lin28a uses distinct mechanisms of binding to RNA and affects positively and negatively miRNA levels

    Hobor, F., Nowak, J. S., Velasco, A., Choudhurry, N., Heikel, G., Kerr, A., Ramos, A. & Michlewski, G., 1 Mar 2017, In: RNA.

    Research output: Contribution to journalArticlepeer-review

  11. Molecular and Genetic Analysis of Condensin Function in Vertebrate Cells

    Hudson, D. F., Ohta, S., Freisinger, T., MacIsaac, F., Sennels, L., Alves, F., Lai, F., Kerr, A., Rappsilber, J. & Earnshaw, W. C., 2008, In: Molecular Biology of the Cell. 19, 7, p. 3070-3079 10 p.

    Research output: Contribution to journalArticlepeer-review

  12. A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci

    Illingworth, R., Kerr, A., De Sousa, D., Jørgensen, H., Ellis, P., Stalker, J., Jackson, D., Clee, C., Plumb, R., Rogers, J. & Bird, A., Jan 2008, In: PLoS Biology. 6, 1, e22.

    Research output: Contribution to journalArticlepeer-review

  13. Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome

    Illingworth, R. S., Gruenewald-Schneider, U., De Sousa, D., Webb, S., Merusi, C., Kerr, A. R. W., James, K. D., Smith, C., Walker, R., Andrews, R. & Bird, A. P., 30 Jan 2015, In: Nucleic Acids Research. 43, 2, p. 732-744 13 p.

    Research output: Contribution to journalArticlepeer-review

  14. Orphan CpG islands identify numerous conserved promoters in the mammalian genome

    Illingworth, R. S., Gruenewald-Schneider, U., Webb, S., Kerr, A. R. W., James, K. D., Turner, D. J., Smith, C., Harrison, D. J., Andrews, R. & Bird, A. P., 2010, In: PLoS Genetics. 6, 9, e1001134.

    Research output: Contribution to journalArticlepeer-review

  15. FG repeats facilitate integral protein trafficking to the inner nuclear membrane

    Kerr, A. R. W. & Schirmer, E. C., 2011, In: Communicative and Integrative Biology . 4, 5, p. 557-559 3 p.

    Research output: Contribution to journalArticlepeer-review

  16. Systematic base composition variation around the genome of Mycoplasma genitalium, but not Mycoplasma pneumoniae

    Kerr, ARW., Peden, JF. & Sharp, PM., Sep 1997, In: Molecular Microbiology. 25, 6, p. 1177-1179 3 p.

    Research output: Contribution to journalLetterpeer-review

  17. Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

    Koerner, M. V., Fitzpatrick, L., Selfridge, J., Guy, J., De Sousa, D., Tillotson, R., Kerr, A., Sun, Z., Lazar, M. A., Lyst, M. J. & Bird, A., 1 Dec 2018, In: Genes & Development. 32, 23-24, p. 1514-1524 11 p.

    Research output: Contribution to journalArticlepeer-review

  18. The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture

    Korfali, N., Wilkie, G. S., Swanson, S. K., Srsen, V., Batrakou, D. G., Fairley, E. A. L., Malik, P., Zuleger, N., Goncharevich, A., de Las Heras, J., Kelly, D. A., Kerr, A. R. W., Florens, L. & Schirmer, E. C., 2010, In: Molecular and Cellular Proteomics. 9, 12, p. 2571-85 15 p.

    Research output: Contribution to journalArticlepeer-review

  19. A multistage sequencing strategy pinpoints many novel and candidate disease alleles for orphan Disease Emery-Dreifuss Muscular Dystrophy and Supports Gene Misregulation as its Pathomechanism

    Meinke, P., Kerr, A., Czapiewski, R., de las Heras, J., Wehnert, M., Schirmer, E., Harris, E., Kölbel, H. & Muntoni, F., 1 Jan 2020, In: EBioMedicine. 51, 102587.

    Research output: Contribution to journalArticlepeer-review

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