Edinburgh Research Explorer

Prof Andrew Jarman

Personal Chair of Developmental Cell Biology

Profile photo

Willingness to take PhD students: Yes

A variety of projects available on gene regulation, cell biology and physiology of auditory mechanosensory cells, using fruitfly, zebrafish and mouse pluripotent cell models

Biography

Andrew Jarman graduated with a 1st class degree in Biochemistry from the University of Oxford. He completed a DPhil in human globin gene regulation at the MRC Molecular Haematology Unit, Nuffield Department of Clinical Medicine, University of Oxford, under supervision of Doug Higgs. After a short period as a postdoctoral assistant at the Institute of Molecular Medicine (Oxford), he obtained a NATO postdoctoral fellowship to join the lab of Yuh Nung and Lily Jan (University of California, San Francisco). After four years, he was recruited to establish his own group at the Wellcome Centre for Cell Biology (University of Edinburgh), where he spent 9 years as a Wellcome Senior Research Fellow. In 2003 he moved to the Centre for Integrative Physiology, initially as a Wellcome Senior Fellow and Reader, and subsequently as Professor of Developmental Cell Biology.

Research Interests

Gene regulation, cell biology and physiology of the generation and maintenance of mechanosensory cells required for hearing

My research in a nutshell

Our senses rely on sense organs that contain highly specialised cells that convert different kinds of stimuli into electrical activity that can then be sent to and processed by our brain. We are particularly interested in the auditory sensory cells of the inner ear, impairment or loss of which leads to deafness. We use zebrafish and fruitfly model organisms to determine how auditory cells are made and how they function. Understanding the gene regulatory network of auditory cell generation and maintenance is a key step in developing new therapeutic approaches to prevent or reverse deafness.

Funding: Wellcome Trust, MRC, BBSRC

CIP staff profile

Teaching

In addition to the teaching contributions to courses shown below, I am Exam Board Convener for Honours Physiology and Exam Board member for Honours Development, Regeneration and Stem Cells. I am external examiner for the undergraduate Biology programme at the University of York).

Undergraduate

Year 1: MBChB Year 1

Year 2: Cells to Organisms 2

Year 3: Mechanisms of Brain Development 3; Developmental Biology 3

Year 4: Honours Physiology; Honours Neuroscience; Honours Development, Regeneration and Stem Cells; Sensory physiology and dysfunction; Patterning in Development

Postgraduate

MSc by Research Integrative Neuroscience; MSc Biomedical Sciences (Life Sciences); MSc Biomedical Sciences (Zhejiang)

 

Qualifications

BA Biochemistry (1st class), University of Oxford

DPhil, University of Oxford

Research students

Sara Goulding (Darwin Trust PhD) 1996-2000

Emma Rawlins (Wellcome Prize PhD) 1998-2001

Eimear Holohan (Wellcome PhD) 2000-2004

Sam Maung (MRC PhD) 2000-2004

Sebastian Cachero (Darwin Trust PhD) 2003-2007

Raphaela Kitson-Pantano (UoE PhD) 2004-2008

Lina Ma (Chinese Scholarship Council PhD) 2006-2010

Fay Newton (BBSRC PhD) 2007-2011

Giuseppe Gallone (MRC PhD) 2008-2012

Daniel Moore (BBSRC PhD) 2009-2014

Katarzyna Styczynska-Soczka (UoE PhD) 2010-2014

Thomas Suslak (EPSRC/MRC Neuroinformatics DTC PhD) 2011-2015

Iain Hunter (BBSRC EASTBIO PhD) 2014-

Alexander Ahl (UoE/Zhejiang partnership PhD) 2015-

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